BE894662A - Inrichting en werkwijze voor het aantonen van de aanwezigheid van antigenen - Google Patents

Inrichting en werkwijze voor het aantonen van de aanwezigheid van antigenen

Info

Publication number
BE894662A
BE894662A BE2/59868A BE2059868A BE894662A BE 894662 A BE894662 A BE 894662A BE 2/59868 A BE2/59868 A BE 2/59868A BE 2059868 A BE2059868 A BE 2059868A BE 894662 A BE894662 A BE 894662A
Authority
BE
Belgium
Prior art keywords
antigens
demonstrating
Prior art date
Application number
BE2/59868A
Other languages
English (en)
Original Assignee
Liotta Lance A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liotta Lance A filed Critical Liotta Lance A
Publication of BE894662A publication Critical patent/BE894662A/nl

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/525—Multi-layer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/805—Test papers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/97—Test strip or test slide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/81—Tube, bottle, or dipstick
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones
    • Y10S436/818—Human chorionic gonadotropin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/82—Hepatitis associated antigens and antibodies
BE2/59868A 1981-10-13 1982-10-11 Inrichting en werkwijze voor het aantonen van de aanwezigheid van antigenen BE894662A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/310,801 US4446232A (en) 1981-10-13 1981-10-13 Enzyme immunoassay with two-zoned device having bound antigens

Publications (1)

Publication Number Publication Date
BE894662A true BE894662A (nl) 1983-04-11

Family

ID=23204169

Family Applications (1)

Application Number Title Priority Date Filing Date
BE2/59868A BE894662A (nl) 1981-10-13 1982-10-11 Inrichting en werkwijze voor het aantonen van de aanwezigheid van antigenen

Country Status (14)

Country Link
US (1) US4446232A (nl)
JP (2) JPS5876763A (nl)
BE (1) BE894662A (nl)
CA (1) CA1200483A (nl)
DE (1) DE3237046A1 (nl)
DK (1) DK159407C (nl)
FR (1) FR2514511B1 (nl)
GB (1) GB2111676B (nl)
GR (1) GR76996B (nl)
IE (1) IE53533B1 (nl)
IT (1) IT1149089B (nl)
LU (1) LU84402A1 (nl)
NL (1) NL192138C (nl)
SE (1) SE462606B (nl)

Families Citing this family (211)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622871A (en) * 1987-04-27 1997-04-22 Unilever Patent Holdings B.V. Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
US4446232A (en) * 1981-10-13 1984-05-01 Liotta Lance A Enzyme immunoassay with two-zoned device having bound antigens
US4604348A (en) * 1981-11-19 1986-08-05 New York Blood Center, Inc. Composition for use in immunoassays
US5073484A (en) * 1982-03-09 1991-12-17 Bio-Metric Systems, Inc. Quantitative analysis apparatus and method
GB8305197D0 (en) * 1983-02-24 1983-03-30 Amersham Int Plc Assay methods
JPS59170768A (ja) * 1983-03-17 1984-09-27 Fuji Photo Film Co Ltd 非アイソト−プアツセイ用多層分析要素およびそれを用いるアツセイ方法
US4549655A (en) * 1983-12-05 1985-10-29 E. I. Du Pont De Nemours And Company Container for a layered chemical analysis system
CA1261743A (en) * 1984-07-23 1989-09-26 Shai Inbar Biological diagnostic assay product, and process utilizing labeled fab fragments
US4617265A (en) * 1984-09-19 1986-10-14 Board Of Regents, University Of Texas System Colony blot assay for enterotoxigenic bacteria
US4826759A (en) * 1984-10-04 1989-05-02 Bio-Metric Systems, Inc. Field assay for ligands
DE3445816C1 (de) * 1984-12-15 1986-06-12 Behringwerke Ag, 3550 Marburg Flaechenfoermiges diagnostisches Mittel
US4764459A (en) * 1984-12-28 1988-08-16 The United States Of America As Represented By The Department Of Health And Human Services Enzyme-linked immunosorbent assay (ELISA) for determining anti-bodies against herpes simplex virus (HSV) types 1 and 2 in human sera
IT1200382B (it) * 1985-02-08 1989-01-18 Boehringer Biochemia Srl Sistema di rilevazione e/o dosaggio di parametri clinici per via immuno enzimatica
US4740468A (en) * 1985-02-14 1988-04-26 Syntex (U.S.A.) Inc. Concentrating immunochemical test device and method
US4859583A (en) * 1985-02-25 1989-08-22 Amoco Corporation Chemiluminescent immunochemical technique for low molecular weight antigens
US5879881A (en) * 1985-04-04 1999-03-09 Hybritech, Incorporated Solid phase system for use in ligand-receptor assays
US4824784A (en) * 1985-04-08 1989-04-25 Hygeia Sciences, Incorporated Chromogenic solution for immunoassay
JPS62502495A (ja) * 1985-04-10 1987-09-24 イムニコン・コ−ポレ−ション 直接均質検定
US4803170A (en) * 1985-05-09 1989-02-07 Ultra Diagnostics Corporation Competitive immunoassay method, device and test kit
US4746631A (en) * 1985-05-09 1988-05-24 Ultra Diagnostics Corporation Immunoassay method, device, and test kit
US4931385A (en) * 1985-06-24 1990-06-05 Hygeia Sciences, Incorporated Enzyme immunoassays and immunologic reagents
US4774177A (en) * 1985-07-15 1988-09-27 Vet-Test Partners Immunoassay method for detection of antibodies and antigens
US4806312A (en) * 1985-08-28 1989-02-21 Miles Inc. Multizone analytical element having detectable signal concentrating zone
US4806311A (en) * 1985-08-28 1989-02-21 Miles Inc. Multizone analytical element having labeled reagent concentration zone
TW203120B (nl) * 1985-10-04 1993-04-01 Abbott Lab
US4868106A (en) * 1985-10-17 1989-09-19 Konishiroku Photo Industry Co., Ltd. Analytical element and method for determining a component in a test sample
US5500350A (en) * 1985-10-30 1996-03-19 Celltech Limited Binding assay device
GB8526741D0 (en) * 1985-10-30 1985-12-04 Boots Celltech Diagnostics Binding assay device
AU6839587A (en) * 1985-12-10 1987-06-30 Murex Corp. Particle-bound binding component immunoassay
US5501949A (en) * 1985-12-10 1996-03-26 Murex Diagnostics Corporation Particle bound binding component immunoassay
US5236826A (en) * 1985-12-10 1993-08-17 Murex Corporation Immunoassay for the detection or quantitation of an analyte
US4868108A (en) * 1985-12-12 1989-09-19 Hygeia Sciences, Incorporated Multiple-antibody detection of antigen
JPH0814582B2 (ja) * 1986-02-20 1996-02-14 富士写真フイルム株式会社 免疫反応物定量用多層分析要素
JPH0750114B2 (ja) * 1986-03-17 1995-05-31 富士写真フイルム株式会社 免疫分析器具を用いる分析方法
US5190864A (en) * 1986-04-15 1993-03-02 Northeastern University Enzyme amplification by using free enzyme to release enzyme from an immobilized enzyme material
US4801726A (en) * 1986-04-15 1989-01-31 Northeastern University Repetitive hit-and-run immunoassay and stable support-analyte conjugates; applied to T-2 toxin
US4937188A (en) * 1986-04-15 1990-06-26 Northeastern University Enzyme activity amplification method for increasing assay sensitivity
US4837145A (en) * 1986-06-09 1989-06-06 Liotta Lance A Layered immunoassay using antibodies bound to transport particles to determine the presence of an antigen
CA1289872C (en) * 1986-06-18 1991-10-01 David L. Woodrum Reversible immobilization of assay reagents in a multizone test device
CA1289876C (en) * 1986-07-15 1991-10-01 Richard R. Anderson Solid phase system incorporating tetrazolium salts for use in ligand-receptor assays
US20010023075A1 (en) * 1992-04-03 2001-09-20 Siu-Yin Wong A immunodiagnositc device having a dessicant incorporated therein
US5763262A (en) * 1986-09-18 1998-06-09 Quidel Corporation Immunodiagnostic device
DE3640318A1 (de) * 1986-11-26 1988-06-09 Boehringer Mannheim Gmbh Verfahren und testtraeger zur bestimmung eines analyten
US4822747A (en) * 1986-12-09 1989-04-18 Miles Inc. Polyacrylamide gel particles having hapten moieties bound thereto as immunoassay reagent
GB8629740D0 (en) * 1986-12-12 1987-01-21 Iq Bio Ltd Immunoassay
ES2004066A6 (es) * 1987-01-21 1988-12-01 Euro Fassel Aktiebolag Metodo para analisis cualitativo y-o cuantitativo de antigenos,anticuerpos yno microorganismos u otras celulas y su correspondiente equipo
AU592174B2 (en) * 1987-02-17 1990-01-04 Genesis Labs, Inc. Immunoassay test strip
AU586552B2 (en) * 1987-02-25 1989-07-13 Genesis Labs, Inc. Dry test strip for devices using oxygen demanding detection system
AU590071B2 (en) * 1987-02-25 1989-10-26 Genesis Labs, Inc. Dry test strips having a red blood cell exclusion layer preventing interference by red blood cells in analyte detection visualization
USRE38430E1 (en) * 1987-03-27 2004-02-17 Becton, Dickinson And Company Solid phase chromatographic immunoassay
CA1303983C (en) * 1987-03-27 1992-06-23 Robert W. Rosenstein Solid phase assay
US4857453A (en) * 1987-04-07 1989-08-15 Syntex (U.S.A.) Inc. Immunoassay device
US4956275A (en) * 1987-04-14 1990-09-11 Molecular Devices Corporation Migratory detection immunoassay
EP1248112A3 (en) 1987-04-27 2004-08-25 Inverness Medical Switzerland GmbH Immunochromatographic specific binding assay device
US4855240A (en) * 1987-05-13 1989-08-08 Becton Dickinson And Company Solid phase assay employing capillary flow
US5238847A (en) * 1987-05-20 1993-08-24 Boehringer Mannheim Gmbh Test kit and process for the determination of an analyte in a pasty sample
DE3716891A1 (de) * 1987-05-20 1988-12-15 Boehringer Mannheim Gmbh Testkit zur bestimmung eines analyten im stuhl
US4883764A (en) * 1987-07-20 1989-11-28 Kloepfer Mary A Blood test strip
IT1223295B (it) * 1987-08-14 1990-09-19 Boehringer Biochemia Srl Dispositivo e metodo immunodiagnostico
FR2621393B1 (fr) * 1987-10-05 1991-12-13 Toledano Jacques Dispositif de detection immunoenzymatique de substances a partir d'une goutte de sang ou de liquide provenant d'un quelconque milieu biologique
DE3740471A1 (de) * 1987-11-28 1989-06-08 Boehringer Mannheim Gmbh Testtraeger zur analyse einer probenfluessigkeit und verfahren zu seiner herstellung
AU2828889A (en) * 1987-12-14 1989-07-19 Lance A. Liotta Layered immunoassay device containing fluid flow barrier
US4870007A (en) * 1987-12-18 1989-09-26 Eastman Kodak Company Immobilized biotinylated receptor in test device, kit and method for determining a ligand
ES2050697T3 (es) * 1987-12-21 1994-06-01 Abbott Lab Metodos y dispositivos de ensayo de fijacion cromatografico.
WO1989006791A1 (en) * 1988-01-21 1989-07-27 Boehringer Mannheim Corporation Apparatus for determining an analyte and method therefor
EP0389563A4 (en) * 1988-01-21 1991-01-23 Boehringer Mannheim Corporation Method and apparatus for analyte determination
WO1989007643A1 (en) * 1988-02-16 1989-08-24 Boehringer Mannheim Corporation Analytical element which avoids premature reaction
USH1664H (en) * 1988-03-09 1997-07-01 Fuji Photo Film Co., Ltd. Analytical element for immunoassay and method for its preparation
FR2630827B1 (fr) * 1988-04-28 1994-06-03 Oris Ind Dispositif et procede pour la determination qualitative et quantitative rapide de la presence d'un ligand reactif dans un fluide
DE3814370A1 (de) * 1988-04-28 1989-11-09 Boehringer Mannheim Gmbh Testtraeger fuer die analyse einer probenfluessigkeit, verfahren zur durchfuehrung einer solchen analyse und herstellungsverfahren
US5013669A (en) * 1988-06-01 1991-05-07 Smithkline Diagnostics, Inc. Mass producible biologically active solid phase devices
US4981785A (en) * 1988-06-06 1991-01-01 Ventrex Laboratories, Inc. Apparatus and method for performing immunoassays
EP0345460B1 (en) * 1988-06-09 1995-09-06 Abbott Laboratories Method and device employing covalently immobilized colored dyes
US5094962A (en) * 1988-06-13 1992-03-10 Eastman Kodak Company Microporous article having a stabilized specific binding reagent, a method for its use and a diagnostic test kit
AU2684488A (en) * 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
FR2634891B1 (fr) * 1988-08-01 1994-05-06 Biotrol Laboratoires Procede et dispositif pour la determination qualitative et/ou quantitative d'un ligand dans un fluide
US5030555A (en) * 1988-09-12 1991-07-09 University Of Florida Membrane-strip reagent serodiagnostic apparatus and method
US5102788A (en) * 1988-11-21 1992-04-07 Hygeia Sciences, Inc. Immunoassay including lyophilized reactant mixture
DE3842702A1 (de) * 1988-12-19 1990-06-21 Boehringer Mannheim Gmbh Testtraeger zur analytischen untersuchung einer probenfluessigkeit mit hilfe einer spezifischen bindungsreaktion zweier bioaffiner bindungspartner und entsprechendes testverfahren
US5028535A (en) * 1989-01-10 1991-07-02 Biosite Diagnostics, Inc. Threshold ligand-receptor assay
US5939272A (en) * 1989-01-10 1999-08-17 Biosite Diagnostics Incorporated Non-competitive threshold ligand-receptor assays
US5200317A (en) * 1989-02-02 1993-04-06 Abbott Laboratories Method and device for quantitative chromatography
US5045480A (en) * 1989-02-09 1991-09-03 Miles Inc. Gel particles having hapten moieties bound thereto as immunoassay reagent
US6352862B1 (en) 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
US5766933A (en) * 1989-04-26 1998-06-16 Diagnostic Products Corporation Method and element for measuring analytes in biological fluids using immobilized binder--analyte labeled complex
DE3941150A1 (de) * 1989-12-13 1991-06-20 Boehringer Mannheim Gmbh Verfahren zur bestimmung eines analyten
US5252496A (en) 1989-12-18 1993-10-12 Princeton Biomeditech Corporation Carbon black immunochemical label
WO1991011714A1 (en) * 1990-01-26 1991-08-08 The United States Of America, Represented By The Secretary, United States Department Of Commerce A method for quantitatively measuring collagenase
US5922615A (en) 1990-03-12 1999-07-13 Biosite Diagnostics Incorporated Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
US5468622A (en) * 1990-04-03 1995-11-21 Immunomatrix, Inc. Salt stabilization of antibody-enzyme conjugates heat-dried into paper
DE4013004C2 (de) * 1990-04-24 1993-10-21 Elvira Schecklies Verfahren zur quantitativen Bestimmung von niedermolekularen organischen Substanzen
US5212060A (en) * 1990-04-27 1993-05-18 Genesis Labs, Inc. Dry test strip comprising a dextran barrier for excluding erythrocytes
US5139934A (en) * 1990-05-25 1992-08-18 Becton, Dickinson And Company Substrate composition and method for solid phase urease immunoassay
ES2089057T3 (es) * 1990-07-18 1996-10-01 Abbott Lab Un reactivo sustituto de un analito para uso en metodos de ensayo de fijacion especifica, dispositivos y kits.
US5166051A (en) * 1990-08-08 1992-11-24 Genesis Labs, Inc. Membranes, membrane overlays for exclusion of erythrocytes, and method for immunoassay of whole blood analytes
US5200321A (en) * 1990-09-07 1993-04-06 The United States Of America As Represented By The Secretary Of The Navy Microassay on a card
US5143852A (en) 1990-09-14 1992-09-01 Biosite Diagnostics, Inc. Antibodies to ligand analogues and their utility in ligand-receptor assays
AU658374B2 (en) * 1990-09-14 1995-04-13 Biosite Diagnostics Incorporated Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
FR2667943B1 (fr) * 1990-10-11 1994-05-13 Jacques Toledano Dispositif et procede pour la determination qualitative et quantitative rapide d'un ligand dans un fluide.
US5166054A (en) * 1991-01-02 1992-11-24 Becton, Dickinson And Company Method for immunoassay using lactoperoxidase, starch and iodine
CA2065719A1 (en) 1991-04-30 1992-10-31 John B. Findlay Nucleic acid amplification and detection methods using rapid polymerase chain reaction cycle
US5607863A (en) * 1991-05-29 1997-03-04 Smithkline Diagnostics, Inc. Barrier-controlled assay device
US5877028A (en) 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
US5869345A (en) * 1991-05-29 1999-02-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing conductive barrier
US5998220A (en) 1991-05-29 1999-12-07 Beckman Coulter, Inc. Opposable-element assay devices, kits, and methods employing them
US6168956B1 (en) 1991-05-29 2001-01-02 Beckman Coulter, Inc. Multiple component chromatographic assay device
US5468648A (en) * 1991-05-29 1995-11-21 Smithkline Diagnostics, Inc. Interrupted-flow assay device
DE4121493A1 (de) * 1991-06-28 1993-01-07 Draegerwerk Ag Analysevorrichtung zur quantitativen, immunologischen bestimmung von schadstoffen
EP0525723B1 (en) * 1991-07-29 1997-05-14 Mochida Pharmaceutical Co., Ltd. Process and device for specific binding assay
WO1993021530A1 (de) * 1992-04-10 1993-10-28 Messerschmitt-Bölkow-Blohm Gmbh Verfahren und vorrichtung zur empfindlichkeits- und selektivitätssteigerung bei immuno-assays, molekül-rezeptor-, dna-komplementär-dna- und gast-wirtsmolekül-wechselwirkungs-assays
DE4217474A1 (de) * 1992-05-27 1993-12-02 Boehringer Mannheim Gmbh Verfahren und Mittel zur Bestimmung eines Analyts
FR2702841B1 (fr) * 1993-03-19 1996-01-26 Toledano Jacques Dispositif et procédé immunologique peptide-anti-peptide.
US5837546A (en) * 1993-08-24 1998-11-17 Metrika, Inc. Electronic assay device and method
FR2709349B1 (fr) 1993-08-25 1995-10-27 Stago Diagnostica Procédé d'identification d'une substance immunologique au moyen d'un système multimembranaire.
US5512448A (en) * 1994-04-28 1996-04-30 Yamazaki; Hiroshi Stabilization of peroxidase conjugates in solution
US5589344A (en) 1994-06-15 1996-12-31 Johnson & Johnson Clinical Diagnostics, Inc. Test kit and method for competitive specific binding assay
US6653066B1 (en) 1994-06-17 2003-11-25 Trinity Biotech Device and method for detecting polyvalent substances
US6686170B1 (en) 1994-08-17 2004-02-03 Abbott Laboratories Assay devices with mobile control reagents
US5597532A (en) * 1994-10-20 1997-01-28 Connolly; James Apparatus for determining substances contained in a body fluid
US5780239A (en) * 1994-11-23 1998-07-14 Carter; Jesse M. Method for the determination of cast in urine
US5569608A (en) * 1995-01-30 1996-10-29 Bayer Corporation Quantitative detection of analytes on immunochromatographic strips
US5739041A (en) * 1995-05-02 1998-04-14 Carter Wallace, Inc. Diagnostic detection device
US20010051350A1 (en) * 1995-05-02 2001-12-13 Albert Nazareth Diagnostic detection device and method
WO1997001759A1 (fr) * 1995-06-28 1997-01-16 Popbb Snc Dispositif de test immunologique perfectionne
US5741714A (en) * 1995-07-18 1998-04-21 Immunivest Corporation Detection of bound analyte by magnetic partitioning and masking
US7635597B2 (en) 1995-08-09 2009-12-22 Bayer Healthcare Llc Dry reagent particle assay and device having multiple test zones and method therefor
US5660990A (en) * 1995-08-18 1997-08-26 Immunivest Corporation Surface immobilization of magnetically collected materials
DE19540541A1 (de) * 1995-10-31 1997-05-07 Human Ges Fuer Biochemica Und Testvorrichtung und Testverfahren
DK0799894T3 (da) * 1996-02-09 2004-08-09 Degussa Fremgangsmåde til fremstilling af (S)-cyanhydriner
US5968839A (en) * 1996-05-13 1999-10-19 Metrika, Inc. Method and device producing a predetermined distribution of detectable change in assays
US5942407A (en) * 1996-06-25 1999-08-24 Immunomatrix, Inc. Light-emitting immunoassay
US5945345A (en) * 1996-08-27 1999-08-31 Metrika, Inc. Device for preventing assay interference using silver or lead to remove the interferant
US6001658A (en) * 1996-09-13 1999-12-14 Diagnostic Chemicals Limited Test strip apparatus and method for determining presence of analyte in a fluid sample
US5879951A (en) * 1997-01-29 1999-03-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing unidirectional flow
US20050101032A1 (en) * 1997-02-10 2005-05-12 Metrika, Inc. Assay device, composition, and method of optimizing assay sensitivity
US5939252A (en) * 1997-05-09 1999-08-17 Lennon; Donald J. Detachable-element assay device
US5895765A (en) * 1997-06-30 1999-04-20 Bayer Corporation Method for the detection of an analyte by immunochromatography
US6436721B1 (en) 1997-07-25 2002-08-20 Bayer Corporation Device and method for obtaining clinically significant analyte ratios
US6824985B1 (en) * 1997-09-09 2004-11-30 Bayer Corporation Formulation for reducing urea effect for immunochromatography assays using urine samples
US5972595A (en) * 1997-12-19 1999-10-26 Nen Life Science Products, Inc. Enzyme assay using a solid phase substrate
US6066446A (en) * 1997-12-19 2000-05-23 Nen Life Science Products, Inc. Assay member and method for its manufacture
US8062908B2 (en) * 1999-03-29 2011-11-22 Orasure Technologies, Inc. Device for collection and assay of oral fluids
US6303081B1 (en) * 1998-03-30 2001-10-16 Orasure Technologies, Inc. Device for collection and assay of oral fluids
ES2501241T3 (es) * 1998-03-30 2014-10-01 Orasure Technologies, Inc. Dispositivo de recolección para análisis de fluidos orales
US20060019404A1 (en) * 1998-05-06 2006-01-26 Blatt Joel M Quantitative assay with extended dynamic range
US7799521B2 (en) * 1998-06-24 2010-09-21 Chen & Chen, Llc Thermal cycling
US6780617B2 (en) 2000-12-29 2004-08-24 Chen & Chen, Llc Sample processing device and method
JP3395673B2 (ja) 1998-11-18 2003-04-14 株式会社豊田中央研究所 微小酸素電極を利用した特異的結合対測定方法
US6171295B1 (en) * 1999-01-20 2001-01-09 Scimed Life Systems, Inc. Intravascular catheter with composite reinforcement
US7577469B1 (en) * 1999-03-11 2009-08-18 Jack L. Aronowitz Noninvasive transdermal systems for detecting an analyte in a biological fluid and methods
DE10003734A1 (de) * 2000-01-28 2001-08-02 Bosch Gmbh Robert Detektionsverfahren und -vorrichtung
US6998273B1 (en) 2000-02-09 2006-02-14 A-Fem Medical Corporation Collection device for lateral flow chromatography
US6365417B1 (en) 2000-02-09 2002-04-02 A-Fem Medical Corporation Collection device for lateral flow chromatography
CA2437298A1 (en) * 2000-02-23 2001-08-30 Besst-Test Aps Method for correlating blood coagulation activity with markers in body fluids, e.g. urine
US6699722B2 (en) 2000-04-14 2004-03-02 A-Fem Medical Corporation Positive detection lateral-flow apparatus and method for small and large analytes
RU2278612C2 (ru) * 2000-07-14 2006-06-27 Лайфскен, Инк. Иммуносенсор
US8124348B2 (en) * 2000-08-23 2012-02-28 Jonathan Zmuda Oral fluid rapid assay for hepatitis C virus (HCV) antibodies using non-antibody labeling of IgA molecules recognizing HCV peptide epitopes
US6584781B2 (en) 2000-09-05 2003-07-01 Enersea Transport, Llc Methods and apparatus for compressed gas
US7087389B2 (en) * 2001-02-09 2006-08-08 Council Of Scientific & Industrial Research Highly cost-effective analytical device for performing immunoassays with ultra high sensitivity
DE10108680A1 (de) * 2001-02-23 2002-09-26 Biognostic Ag Affinitätsassay zur schnellen Untersuchung biologischer Materialien
US20050266499A1 (en) * 2001-04-25 2005-12-01 Rockeby Biomed Corporation, Ltd. Method and apparatus for testing for presence or absence of select biological substances
AT5044U1 (de) * 2001-05-10 2002-02-25 Medsystems Diagnostics Gmbh Quantitativer einschritt immuntest in lyophilisierter form
US7531362B2 (en) * 2001-06-07 2009-05-12 Medmira Inc. Rapid diagnostic assay
US7300633B2 (en) 2001-07-25 2007-11-27 Oakville Hong Kong Company Limited Specimen collection container
US7270959B2 (en) 2001-07-25 2007-09-18 Oakville Hong Kong Company Limited Specimen collection container
EP1427531B1 (en) 2001-09-11 2016-10-19 Iquum, Inc. Sample vessels
US20030124618A1 (en) * 2001-12-04 2003-07-03 Lattec I/S Device for analysing analyte compounds and use hereof
US7459127B2 (en) * 2002-02-26 2008-12-02 Siemens Healthcare Diagnostics Inc. Method and apparatus for precise transfer and manipulation of fluids by centrifugal and/or capillary forces
US20030180814A1 (en) * 2002-03-21 2003-09-25 Alastair Hodges Direct immunosensor assay
US20060134713A1 (en) * 2002-03-21 2006-06-22 Lifescan, Inc. Biosensor apparatus and methods of use
JP3637392B2 (ja) * 2002-04-08 2005-04-13 独立行政法人産業技術総合研究所 燃料電池
US20030232401A1 (en) * 2002-06-12 2003-12-18 Pugia Michael J. Bacterial test method by glycated label binding
US7108993B2 (en) * 2002-07-19 2006-09-19 Bayer Healthcare Llc Use of dual conjugated labels in the elimination of serum interference in immunochromatographic assays
US20040038197A1 (en) * 2002-08-22 2004-02-26 Usda Ars Ott Extraction and concentration method
US20040092036A1 (en) * 2002-09-11 2004-05-13 Lattec I/S Device for analysing analyte compounds and use hereof
US7093166B2 (en) * 2002-10-08 2006-08-15 Dell Products L.P. Method and apparatus for testing physical memory in an information handling system under conventional operating systems
US7094354B2 (en) * 2002-12-19 2006-08-22 Bayer Healthcare Llc Method and apparatus for separation of particles in a microfluidic device
US7125711B2 (en) * 2002-12-19 2006-10-24 Bayer Healthcare Llc Method and apparatus for splitting of specimens into multiple channels of a microfluidic device
CA2511372C (en) * 2002-12-26 2014-07-08 Jeff D. Debad Methods, compositions and kits for biomarker extraction
US7560272B2 (en) 2003-01-04 2009-07-14 Inverness Medical Switzerland Gmbh Specimen collection and assay container
US7718421B2 (en) 2003-02-05 2010-05-18 Iquum, Inc. Sample processing
US8101429B2 (en) * 2003-06-03 2012-01-24 Siemens Healthcare Diagnostics Inc. Native analyte as a reference in lateral flow assays
US20040265172A1 (en) * 2003-06-27 2004-12-30 Pugia Michael J. Method and apparatus for entry and storage of specimens into a microfluidic device
US20080257754A1 (en) * 2003-06-27 2008-10-23 Pugia Michael J Method and apparatus for entry of specimens into a microfluidic device
US20040265171A1 (en) * 2003-06-27 2004-12-30 Pugia Michael J. Method for uniform application of fluid into a reactive reagent area
US7347617B2 (en) * 2003-08-19 2008-03-25 Siemens Healthcare Diagnostics Inc. Mixing in microfluidic devices
US7517495B2 (en) 2003-08-25 2009-04-14 Inverness Medical Switzerland Gmbh Biological specimen collection and analysis system
US7943395B2 (en) * 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US7150995B2 (en) * 2004-01-16 2006-12-19 Metrika, Inc. Methods and systems for point of care bodily fluid analysis
US20050227370A1 (en) * 2004-03-08 2005-10-13 Ramel Urs A Body fluid analyte meter & cartridge system for performing combined general chemical and specific binding assays
US7319032B2 (en) * 2004-04-22 2008-01-15 Medtox Non-sugar sweeteners for use in test devices
DE102006058374A1 (de) * 2006-12-08 2008-07-03 Biosensor Gmbh Analyseverfahren und portables Analysegerät
EP2304437A4 (en) * 2008-07-22 2012-06-20 Siemens Healthcare Diagnostics DIAGNOSTIC AID SPECIFIC TO A DISEASE
US8012770B2 (en) 2009-07-31 2011-09-06 Invisible Sentinel, Inc. Device for detection of antigens and uses thereof
MX2012004105A (es) 2009-10-09 2012-09-07 Invisible Sentinel Inc Dispositivo para deteccion de antigenos y usos del mismo.
KR101271022B1 (ko) * 2009-11-24 2013-06-04 주식회사 인포피아 다공성 필름이 부착되어 있는 멤브레인 바이오센서 및 이를 이용한 면역반응 또는 효소반응 측정방법
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
EP2668501B1 (en) 2011-01-27 2019-06-12 Invisible Sentinel, Inc. Analyte detection devices, multiplex and tabletop devices for detection of analytes, and uses thereof
WO2013088429A1 (en) * 2011-12-13 2013-06-20 Kieran Gerard Walshe A homogeneous competitive lateral flow assay
US8293487B1 (en) * 2012-01-06 2012-10-23 Jiandi Zhang Zestern, a simple, fast, specific and quantifiable improvement of immunodetection process
EP2823308B1 (en) 2012-03-09 2019-05-22 Invisible Sentinel, Inc. Methods and compositions for detecting multiple analytes with a single signal
US20130280696A1 (en) 2012-04-23 2013-10-24 Elliott Millenson Devices and methods for detecting analyte in bodily fluid
US9528941B2 (en) 2012-08-08 2016-12-27 Scanadu Incorporated Method and apparatus for determining analyte concentration by quantifying and interpreting color information captured in a continuous or periodic manner
US9311520B2 (en) 2012-08-08 2016-04-12 Scanadu Incorporated Method and apparatus for performing and quantifying color changes induced by specific concentrations of biological analytes in an automatically calibrated environment
US9285323B2 (en) 2012-08-08 2016-03-15 Scanadu Incorporated Quantifying color changes of chemical test pads induced concentrations of biological analytes under different lighting conditions
WO2015085209A1 (en) * 2013-12-06 2015-06-11 President And Fellows Of Harvard College Paper-based synthetic gene networks
US9863811B2 (en) 2014-08-15 2018-01-09 Scanadu Incorporated Precision luxmeter methods for digital cameras to quantify colors in uncontrolled lighting environments
US9927443B2 (en) 2015-04-10 2018-03-27 Conquerab Inc. Risk assessment for therapeutic drugs
WO2017079653A2 (en) 2015-11-06 2017-05-11 Vetica Labs, Inc. Methods of detecting inflammatory markers and treating inflammatory conditions in companion animals
US9903866B2 (en) 2016-04-05 2018-02-27 Conquerab Inc. Portable devices for detection of antibodies against therapeutic drugs
WO2020241871A1 (ja) * 2019-05-30 2020-12-03 国立大学法人北海道大学 物質検出装置

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3654090A (en) * 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
NL154600B (nl) * 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
US3723064A (en) * 1971-07-26 1973-03-27 L Liotta Method and device for determining the concentration of a material in a liquid
FI49086C (fi) * 1973-01-25 1975-03-10 Matti Antero Reunanen Radioimmunologinen määritysmenetelmä.
US3926732A (en) * 1973-02-16 1975-12-16 Alfa Laval Ab Method for assaying catalase in milk and other liquids
US3992158A (en) * 1973-08-16 1976-11-16 Eastman Kodak Company Integral analytical element
US4039652A (en) * 1973-10-11 1977-08-02 Miles Laboratories, Inc. Column method of immunoassay employing an immobilized binding partner
SE388694B (sv) * 1975-01-27 1976-10-11 Kabi Ab Sett att pavisa ett antigen exv i prov av kroppvetskor, med utnyttjande av till porost berarmaterial bundna eller adsorberande antikroppar
CA1054034A (en) * 1975-06-20 1979-05-08 Barbara J. Bruschi Multilayer analytical element
US4042335A (en) * 1975-07-23 1977-08-16 Eastman Kodak Company Integral element for analysis of liquids
US4016043A (en) * 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
US4059407A (en) * 1976-04-14 1977-11-22 Becton, Dickinson And Company Disposable chemical indicators
US4094647A (en) * 1976-07-02 1978-06-13 Thyroid Diagnostics, Inc. Test device
JPS5344622A (en) * 1976-09-30 1978-04-21 Mochida Pharm Co Ltd Immunologically measuring method
US4200690A (en) * 1976-12-16 1980-04-29 Millipore Corporation Immunoassay with membrane immobilized antibody
CA1095819A (en) * 1977-01-14 1981-02-17 Eastman Kodak Company Element for analysis of liquids
US4277560A (en) * 1978-10-24 1981-07-07 Technicon Instruments Corporation Enzyme immunoassays using immobilized reagents in a flowing stream
JPH0142041Y2 (nl) * 1978-12-11 1989-12-11
US4258001A (en) * 1978-12-27 1981-03-24 Eastman Kodak Company Element, structure and method for the analysis or transport of liquids
US4181501A (en) * 1979-03-26 1980-01-01 General Electric Company Method and apparatus for measuring antibody levels
US4264560A (en) * 1979-12-26 1981-04-28 Samuel Natelson Clinical analytical system
JPS5767860A (en) * 1980-10-15 1982-04-24 Fuji Photo Film Co Ltd Material for multilayer analysis
US4446232A (en) * 1981-10-13 1984-05-01 Liotta Lance A Enzyme immunoassay with two-zoned device having bound antigens

Also Published As

Publication number Publication date
DK159407B (da) 1990-10-08
IE822464L (en) 1983-04-13
JPH0416745B2 (nl) 1992-03-25
JPH0464062A (ja) 1992-02-28
NL8203946A (nl) 1983-05-02
FR2514511B1 (fr) 1986-02-21
IT8249171A0 (it) 1982-09-27
JPS5876763A (ja) 1983-05-09
SE8205751D0 (sv) 1982-10-08
NL192138B (nl) 1996-10-01
GR76996B (nl) 1984-09-04
GB2111676A (en) 1983-07-06
US4446232A (en) 1984-05-01
IE53533B1 (en) 1988-12-07
IT1149089B (it) 1986-12-03
NL192138C (nl) 1997-02-04
DE3237046C2 (nl) 1988-08-04
LU84402A1 (fr) 1983-06-13
FR2514511A1 (fr) 1983-04-15
DK159407C (da) 1991-04-02
GB2111676B (en) 1985-08-21
DK451982A (da) 1983-04-14
CA1200483A (en) 1986-02-11
DE3237046A1 (de) 1983-04-21
SE462606B (sv) 1990-07-23
SE8205751L (sv) 1983-04-14

Similar Documents

Publication Publication Date Title
BE894662A (nl) Inrichting en werkwijze voor het aantonen van de aanwezigheid van antigenen
BE886332A (nl) Werkwijze en inrichting voor het uitvoeren van elektrolyses
NL190967C (nl) Werkwijze voor het verbergen of camoufleren van zichtbare en infrarode straling en inrichting daarvoor.
BE888883A (nl) Werkwijze en inrichting voor het verpakken van lasten
NL7902774A (nl) Werkwijze en inrichting voor het verstuiven van vloeistof.
BE881457A (nl) Werkwijze en inrichting voor het detecteren van bewegende en elektrisch afhankelijke domeinen
NL7806290A (nl) Werkwijze en stelsel voor het op ultrasone wijze onder- zoeken van voorwerpen.
NL7712634A (nl) Werkwijze en inrichting voor het vroegtijdig vaststellen van scheuren.
NL193037B (nl) Werkwijze en inrichting voor het bewerken van spraak.
BE873779A (nl) Werkwijze en inrichting voor het compenseren van aftastinrichting
BE892601A (nl) Inrichting voor het verwijderen van de nek van een slachtkuiken
NL7803047A (nl) Werkwijze en inrichting voor het pneumatisch verstuiven van vloeistoffen.
NL7904529A (nl) Werkwijze en inrichting voor het vervaardigen van glas- panelen.
NL188962C (nl) Werkwijze voor het bepalen van antigenen en antilichamen.
NL187936C (nl) Werkwijze en inrichting voor het bepalen van de alcoholconcentratie van bloed.
BE854881A (nl) Werkwijze en inrichting voor het afscheiden van deeltjes
NL7801748A (nl) Werkwijze en inrichting voor het verdelen van glasvezels.
BE872517A (nl) Werkwijze en inrichting voor het doorlopend bereiden van fotografische emulsies
NL193942B (nl) Inrichting en werkwijze voor het coaten van glas.
BE894317A (nl) Werkwijze en inrichting voor het vervaardigen van glasflessen
NL189179C (nl) Werkwijze en inrichting voor het bewerken van oppervlakken.
BE892259A (nl) Condensator en werkwijze en inrichting voor het vervaardigen daarvan
NL7803396A (nl) Werkwijze en inrichting voor het overdragen van beelden.
NL188480C (nl) Werkwijze en inrichting voor het automatisch controleren op vervormingen van een constructie.
NL7809855A (nl) Werkwijze en inrichting voor het indentificeren van voorwerpen.