BE882710A - Nouveaux amides d'antibiotiques du groupe des macrolides polyeniques et leurs derives, ainsi que leur procede de preparation - Google Patents

Nouveaux amides d'antibiotiques du groupe des macrolides polyeniques et leurs derives, ainsi que leur procede de preparation

Info

Publication number
BE882710A
BE882710A BE0/200168A BE200168A BE882710A BE 882710 A BE882710 A BE 882710A BE 0/200168 A BE0/200168 A BE 0/200168A BE 200168 A BE200168 A BE 200168A BE 882710 A BE882710 A BE 882710A
Authority
BE
Belgium
Prior art keywords
antibiotics
derivatives
preparation process
novel amides
macrolide group
Prior art date
Application number
BE0/200168A
Other languages
English (en)
Inventor
L Falkowski
A Jarzebski
B Stefanska
E Troka
E Borowski
Original Assignee
Politechnika Gdanska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Politechnika Gdanska filed Critical Politechnika Gdanska
Publication of BE882710A publication Critical patent/BE882710A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BE0/200168A 1979-04-09 1980-04-09 Nouveaux amides d'antibiotiques du groupe des macrolides polyeniques et leurs derives, ainsi que leur procede de preparation BE882710A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL1979214802A PL122086B1 (en) 1979-04-09 1979-04-09 Process for preparing amides of antibiotics from the group of polyene macrolides and their derivativesvykh makrolidov i ikh proizvodnykh

Publications (1)

Publication Number Publication Date
BE882710A true BE882710A (fr) 1980-07-31

Family

ID=19995636

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/200168A BE882710A (fr) 1979-04-09 1980-04-09 Nouveaux amides d'antibiotiques du groupe des macrolides polyeniques et leurs derives, ainsi que leur procede de preparation

Country Status (12)

Country Link
US (1) US4783527A (fr)
JP (1) JPS55157598A (fr)
BE (1) BE882710A (fr)
DE (1) DE3013631C2 (fr)
FI (1) FI70226C (fr)
FR (1) FR2453645A1 (fr)
GB (1) GB2049658B (fr)
NL (1) NL8002086A (fr)
NO (1) NO800995L (fr)
PL (1) PL122086B1 (fr)
SE (1) SE450639B (fr)
SU (2) SU1017165A3 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2598434B1 (fr) * 1986-05-12 1988-09-16 Pf Medicament Nouveaux immunomodulateurs obtenus par hemisynthese a partir d'un polysaccharide bacterien isole d'une souche mutante non capsulee de klebsiella pneumoniae
FR2614306B1 (fr) * 1987-04-22 1989-07-28 Pf Medicament Nouveau derive de d.25, procede de preparation, utilisation a titre d'agent immunostimulant et compositions pharmaceutiques le contenant.
DE3836599A1 (de) * 1988-10-27 1990-05-03 Wolff Walsrode Ag Neue polysaccharide, verfahren zu ihrer herstellung und ihre verwendung
IT1237772B (it) * 1989-11-16 1993-06-17 Tiberio Bruzzese Derivati di macrolidi polienici.
IT1243404B (it) * 1990-12-03 1994-06-10 Prodotti Antibiotici Spa Derivati della partricina
WO2001051061A1 (fr) * 2000-01-14 2001-07-19 Intrabiotics Pharmaceuticals, Inc. Derives de macrolides de polyene, preparation et utilisations correspondantes
US6664241B2 (en) * 2000-05-31 2003-12-16 Micrologix Biotech Inc. Water-soluble amide derivatives of polyene macrolides and preparation and uses thereof
US20090221520A1 (en) * 2005-03-23 2009-09-03 Francisco Malpartida Romero Polyene Antibiotics, Compositions Containing Said Antibiotics, Method and Micro-Organisms Used to Obtain Same and Applications Thereof
ES2323397B1 (es) * 2005-08-03 2010-04-23 Consejo Sup. De Invest. Cientificas Macrolidos polienos metilados, procedimiento para su obtencion y sus aplicaciones.
ES2323253B1 (es) * 2005-03-23 2010-04-23 Consejo Sup. De Invest. Cientificas Nuevos polienos amidados, procedimiento para su obtencion y aplicaciones.
JP2010534688A (ja) * 2007-07-30 2010-11-11 上海医薬工業研究院 ポリエン類抗生物質ジエステル化合物
MX365184B (es) * 2010-12-21 2019-05-21 Centro De Investig Y De Estudios Avanzados Del I P N Nuevos compuestos analogos de la anfotericina y composiciones farmaceuticas que los contienen.
CN106414473B (zh) 2014-06-12 2020-03-13 盐野义制药株式会社 多烯大环内酯衍生物
JP2022523325A (ja) 2019-01-31 2022-04-22 シグマ－アルドリッチ・カンパニー・リミテッド・ライアビリティ・カンパニー 水溶性が改善された抗真菌剤
MX2022001678A (es) * 2019-08-08 2022-05-18 Univ Illinois Derivados amidas hibridas de anfotericina b.
RU2751333C1 (ru) * 2020-12-16 2021-07-13 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт по изысканию новых антибиотиков имени Г.Ф. Гаузе" Способ получения противогрибкового полусинтетического полиенового антибиотика

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4035568A (en) * 1971-06-07 1977-07-12 Rutgers Research And Educational Foundation Derivatives of polyene macrolide antibiotics
US4041232A (en) * 1976-02-23 1977-08-09 E. R. Squibb & Sons, Inc. Amphotericin B methyl ester salts
PL100966B1 (pl) * 1976-04-22 1978-11-30 Sposob otrzymywania n-glikozylowych pochodnych makrolidow polienowych oraz ich soli,zwlaszcza soli n-metyloglukaminowej

Also Published As

Publication number Publication date
SU1152954A1 (ru) 1985-04-30
SU1017165A3 (ru) 1983-05-07
JPS55157598A (en) 1980-12-08
PL214802A1 (fr) 1980-12-01
FI70226B (fi) 1986-02-28
DE3013631C2 (de) 1986-08-28
SE450639B (sv) 1987-07-13
PL122086B1 (en) 1982-06-30
US4783527A (en) 1988-11-08
NL8002086A (nl) 1980-10-13
JPS5728715B2 (fr) 1982-06-18
FR2453645B1 (fr) 1982-11-19
SE8002627L (sv) 1980-10-10
FR2453645A1 (fr) 1980-11-07
NO800995L (no) 1980-10-10
GB2049658B (en) 1983-08-03
FI70226C (fi) 1986-09-15
FI801099A (fi) 1980-10-10
DE3013631A1 (de) 1980-10-23
GB2049658A (en) 1980-12-31

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: POLITECHNIKA GDANSKA

Effective date: 19920430