BE873731A - 9-deoxy-9a-methylene isosteres de pg12 et procede pour les preparer - Google Patents

9-deoxy-9a-methylene isosteres de pg12 et procede pour les preparer

Info

Publication number
BE873731A
BE873731A BE193094A BE193094A BE873731A BE 873731 A BE873731 A BE 873731A BE 193094 A BE193094 A BE 193094A BE 193094 A BE193094 A BE 193094A BE 873731 A BE873731 A BE 873731A
Authority
BE
Belgium
Prior art keywords
emi
formula
compound
compounds
group
Prior art date
Application number
BE193094A
Other languages
English (en)
French (fr)
Inventor
C Gandolfi
C Passarotti
W Fava
A Fumagalli
F Faustini
R Ceserani
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of BE873731A publication Critical patent/BE873731A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/06—Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BE193094A 1978-01-26 1979-01-26 9-deoxy-9a-methylene isosteres de pg12 et procede pour les preparer BE873731A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT7819616A IT7819616A0 (it) 1978-01-26 1978-01-26 9-deossi-9a-metilene-isosteri della pgi 2.
KR7900219A KR840000948B1 (ko) 1978-01-26 1979-01-25 PGI_2의 9-데옥시-9a-메틸렌 등배전자체의 제조방법
AU14048/83A AU556110B2 (en) 1978-01-26 1983-04-28 9-deoxy-9a-methylene isoesters of pg12

Publications (1)

Publication Number Publication Date
BE873731A true BE873731A (fr) 1979-07-26

Family

ID=36794902

Family Applications (1)

Application Number Title Priority Date Filing Date
BE193094A BE873731A (fr) 1978-01-26 1979-01-26 9-deoxy-9a-methylene isosteres de pg12 et procede pour les preparer

Country Status (8)

Country Link
KR (1) KR840000948B1 (cs)
AU (1) AU556110B2 (cs)
BE (1) BE873731A (cs)
CS (2) CS215150B2 (cs)
HU (1) HU182726B (cs)
IT (1) IT7819616A0 (cs)
SU (1) SU1360582A3 (cs)
ZA (1) ZA79268B (cs)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0038131A3 (en) * 1980-04-11 1982-02-03 Sumitomo Chemical Company, Limited Bicyclooctane compounds, their production, compositions containing them and their pharmaceutical use
DE3618538A1 (de) * 1985-06-04 1986-12-18 Nisshin Flour Milling Co., Ltd., Tokio/Tokyo Optisch aktive carbacyclin-zwischenprodukte und verfahren zu ihrer herstellung
US4837342A (en) * 1986-02-28 1989-06-06 Sagami Chemical Research Center Prostacyclin analogue, and blood circulation improving agent and anti-ulcer composition containing it as active ingredient

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0038131A3 (en) * 1980-04-11 1982-02-03 Sumitomo Chemical Company, Limited Bicyclooctane compounds, their production, compositions containing them and their pharmaceutical use
DE3618538A1 (de) * 1985-06-04 1986-12-18 Nisshin Flour Milling Co., Ltd., Tokio/Tokyo Optisch aktive carbacyclin-zwischenprodukte und verfahren zu ihrer herstellung
US4837342A (en) * 1986-02-28 1989-06-06 Sagami Chemical Research Center Prostacyclin analogue, and blood circulation improving agent and anti-ulcer composition containing it as active ingredient

Also Published As

Publication number Publication date
CS215150B2 (en) 1982-07-30
AU1404883A (en) 1984-01-12
ZA79268B (en) 1980-01-30
KR840000948B1 (ko) 1984-07-01
HU182726B (en) 1984-03-28
AU556110B2 (en) 1986-10-23
KR830000687A (ko) 1983-04-18
CS215149B2 (en) 1982-07-30
IT7819616A0 (it) 1978-01-26
SU1360582A3 (ru) 1987-12-15

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: FARMITALIA CARLO ERBA S.P.A.

Effective date: 19900131