IT7819616A0 - 9-deossi-9a-metilene-isosteri della pgi 2. - Google Patents
9-deossi-9a-metilene-isosteri della pgi 2.Info
- Publication number
- IT7819616A0 IT7819616A0 IT7819616A IT1961678A IT7819616A0 IT 7819616 A0 IT7819616 A0 IT 7819616A0 IT 7819616 A IT7819616 A IT 7819616A IT 1961678 A IT1961678 A IT 1961678A IT 7819616 A0 IT7819616 A0 IT 7819616A0
- Authority
- IT
- Italy
- Prior art keywords
- isosteres
- pgi
- deoxy
- methylene
- Prior art date
Links
- 101710129448 Glucose-6-phosphate isomerase 2 Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
- C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
- C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/02—Five-membered rings
- C07D339/06—Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (49)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT7819616A IT7819616A0 (it) | 1978-01-26 | 1978-01-26 | 9-deossi-9a-metilene-isosteri della pgi 2. |
GB7944136A GB2038333B (en) | 1978-01-26 | 1979-01-15 | 12 -formyl- (20 12)octanor-9-deoxy-9 -methylene pgi derivatives |
GB7901474A GB2013661B (en) | 1978-01-26 | 1979-01-15 | 9-deoxy-9 -methylene isosteres of pgi2 |
GB7944137A GB2040928B (en) | 1978-01-26 | 1979-01-15 | Bicycloalkane derivatives useful as intermediates in preparing pg1 isosteres |
AU43438/79A AU530571B2 (en) | 1978-01-26 | 1979-01-17 | 9-deoxy-9a-methylene-isosteres of pgi2 |
NL7900369A NL7900369A (nl) | 1978-01-26 | 1979-01-17 | 9-deoxy-9a-methyleen-isosteren van pgi2 en werkwijzen ter bereiding ervan. |
FI790178A FI72509C (fi) | 1978-01-26 | 1979-01-19 | Foerfarande foer framstaellning av 9-deoxi-9a-metylen-isosterer av pgi2. |
IL56468A IL56468A (en) | 1978-01-26 | 1979-01-19 | 9-deoxy-9a-methylene isosteres of pgi2,process for their preparation and pharmaceutical and veterinary compositions containing them |
AT0045279A AT374165B (de) | 1978-01-26 | 1979-01-22 | Verfahren zum herstellen von neuen 9-deoxy-9a -methylen-isosteren von pgl2 |
DE19792902442 DE2902442A1 (de) | 1978-01-26 | 1979-01-23 | 9-deoxy-9a-methylen-isostere von pgi tief 2 , verfahren zu ihrer herstellung und sie enthaltende pharmazeutische und veterinaermedizinische mittel |
ZA79268A ZA79268B (en) | 1978-01-26 | 1979-01-23 | 9-deoxy-9a-methylene isosteres of pgi2 and process for their preparation |
CS804928A CS215150B2 (en) | 1978-01-26 | 1979-01-23 | Method of making the 9-deoxy-9a-methylenisosters of the prostacycline pgi2 |
CS79513A CS215149B2 (en) | 1978-01-26 | 1979-01-23 | Method of making the 9-deoxy-9a-methylenisosters of the prostacycline |
YU00155/79A YU15579A (en) | 1978-01-26 | 1979-01-24 | Process for obtaining 9-deoxy-9a-methylene-isoesters pgi2 |
NZ189461A NZ189461A (en) | 1978-01-26 | 1979-01-24 | 9-deoxy-9a-methylene-isoteres of pgi2 and pharmaceutical compositions intermediates |
NZ194253A NZ194253A (en) | 1978-01-26 | 1979-01-24 | 9-deoxy-9a-methylene isosteres |
GR58188A GR73109B (it) | 1978-01-26 | 1979-01-25 | |
SE7900685A SE453291B (sv) | 1978-01-26 | 1979-01-25 | 9-deoxi-9a-metylenisosterer av pgi?712, forfarande for framstellning av dem och en farmaceutisk eller veterinermedicinsk komposition |
ES477172A ES477172A1 (es) | 1978-01-26 | 1979-01-25 | Procedimiento para la preparacion de 9-deoxi-9a-metilen isosteros de pgi2. |
KR7900219A KR840000948B1 (ko) | 1978-01-26 | 1979-01-25 | PGI_2의 9-데옥시-9a-메틸렌 등배전자체의 제조방법 |
HU79EA191A HU182726B (en) | 1978-01-26 | 1979-01-25 | Process for producing the 9-desoxy-9a-methylene-isosteres of pgi2/prostacyclin/ |
CH764/79A CH647222A5 (de) | 1978-01-26 | 1979-01-25 | 9-desoxy-9a-methylen-isostere von pgi-2 und verfahren zu deren herstellung. |
PT7969129A PT69129A (en) | 1978-01-26 | 1979-01-25 | Process for the preparation of 9-deoxy-9a-methylene isosteres of pgi2 |
SU792719752A SU1053745A3 (ru) | 1978-01-26 | 1979-01-25 | Способ получени 9-дезокси-9 @ -метиленизостеров @ или их лактонов или их солей |
NO790257A NO153926C (no) | 1978-01-26 | 1979-01-25 | Fremgangsmaate ved fremstilling av 9-desoksy-9a-metylen-isotere av pgi2. |
CA000320354A CA1209133A (en) | 1978-01-26 | 1979-01-26 | 9-deoxy-9a-methylene isosteres of pgi.sub.2 and process for their preparation |
DK35779A DK35779A (da) | 1978-01-26 | 1979-01-26 | 9-deoxy-9a-methylen-isostere af pg12 og fremgangsmaade til fremstilling deraf |
BE193094A BE873731A (fr) | 1978-01-26 | 1979-01-26 | 9-deoxy-9a-methylene isosteres de pg12 et procede pour les preparer |
JP864479A JPS54119444A (en) | 1978-01-26 | 1979-01-26 | 99deoxyy9aamethylene isostere of pg12 and its manufacture |
FR7902082A FR2422634A1 (fr) | 1978-01-26 | 1979-01-26 | Isosteres de type 9-desoxy-9a-methylene de pgi2, utiles comme medicaments, et leur procede de preparation |
IE145/79A IE48311B1 (en) | 1978-01-26 | 1979-01-30 | 9-deoxy-9a-methylene isosteres of pg12 and process for their preparation |
FR7923143A FR2466445A1 (fr) | 1978-01-26 | 1979-09-17 | Formyl-2 bicyclo-alcanes, intermediaires de synthese d'isosteres de type 9-desoxy-9a-methylene de pgi2 |
FR7923142A FR2466446A1 (fr) | 1978-01-26 | 1979-09-17 | Bicyclo-alcanones, intermediaires de la preparation d'isosteres de type 9-desoxy-9a-methylene de pgi2 |
US06/124,715 US4307112A (en) | 1978-01-26 | 1980-02-26 | 9-Deoxy-9A-methylene isosteres of PGI2 and process for their preparation |
SU802930648A SU1360582A3 (ru) | 1978-01-26 | 1980-06-05 | Способ получени 9-деокси-9а-метилен-изостеров ПГJ @ или их лактонов |
AT0550081A AT375633B (de) | 1978-01-26 | 1981-12-21 | Verfahren zum herstellen von neuen 9-deoxy-9a-methylen-isosteren von pgi2 |
CA000401255A CA1209134A (en) | 1978-01-26 | 1982-04-19 | 9-deoxy-9a-methylene isosteres of pgi.sub.2 and process for their preparation |
CA000401256A CA1198417A (en) | 1978-01-26 | 1982-04-19 | 9-deoxy-9a-methylene isosteres of pgi.sub.2 and process for their preparation |
CA000416724A CA1198418A (en) | 1978-01-26 | 1982-11-30 | 9-deoxy-9a-methylene isosters of pgi.sub.2 and process for their preparation |
CA000416725A CA1198419A (en) | 1978-01-26 | 1982-11-30 | 9-deoxy-9a-methylene isosteres of pgi.sub.2 and process for their preparation |
CA000416726A CA1198420A (en) | 1978-01-26 | 1982-11-30 | 9-deoxy-9a-methylene isosteres of pgi.sub.2 and process for their preparation |
SG40/83A SG4083G (en) | 1978-01-26 | 1983-01-24 | 9-deoxy-9a-methylene isosteres of pg12 |
YU217/83A YU42835B (en) | 1978-01-26 | 1983-02-01 | Process for obtaining 9-deoxy-9a-methylene-isoesters pgi2 |
KE3262A KE3262A (en) | 1978-01-26 | 1983-02-05 | 9-deoxy-9a-methylene isosteres of pgi2 |
AU14048/83A AU556110B2 (en) | 1978-01-26 | 1983-04-28 | 9-deoxy-9a-methylene isoesters of pg12 |
HK184/83A HK18483A (en) | 1978-01-26 | 1983-06-02 | 9-deoxy-9a-methylene isosteres of pg12 |
SE8303479A SE453289B (sv) | 1978-01-26 | 1983-06-17 | Mellanprodukter for framstellning av 9-deoxi-9a-metylenisosterer av pgi?712 samt forfarande for framstellning av dem |
FI833908A FI73963C (fi) | 1978-01-26 | 1983-10-26 | Nya 9-deoxi-9a-metylen-isosterer och foerfarande foer deras framstaellning. |
MY104/84A MY8400104A (en) | 1978-01-26 | 1984-12-30 | 9-deoxy-9a-methylene isosteres of pg12 |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT7819616A IT7819616A0 (it) | 1978-01-26 | 1978-01-26 | 9-deossi-9a-metilene-isosteri della pgi 2. |
KR7900219A KR840000948B1 (ko) | 1978-01-26 | 1979-01-25 | PGI_2의 9-데옥시-9a-메틸렌 등배전자체의 제조방법 |
AU14048/83A AU556110B2 (en) | 1978-01-26 | 1983-04-28 | 9-deoxy-9a-methylene isoesters of pg12 |
Publications (1)
Publication Number | Publication Date |
---|---|
IT7819616A0 true IT7819616A0 (it) | 1978-01-26 |
Family
ID=36794902
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT7819616A IT7819616A0 (it) | 1978-01-26 | 1978-01-26 | 9-deossi-9a-metilene-isosteri della pgi 2. |
Country Status (8)
Country | Link |
---|---|
KR (1) | KR840000948B1 (it) |
AU (1) | AU556110B2 (it) |
BE (1) | BE873731A (it) |
CS (2) | CS215150B2 (it) |
HU (1) | HU182726B (it) |
IT (1) | IT7819616A0 (it) |
SU (1) | SU1360582A3 (it) |
ZA (1) | ZA79268B (it) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56145239A (en) * | 1980-04-11 | 1981-11-11 | Sumitomo Chem Co Ltd | Novel bicyclooctane derivative and its preparation |
JPS61280294A (ja) * | 1985-06-04 | 1986-12-10 | Nisshin Flour Milling Co Ltd | 光学活性カルバサイクリン中間体の製造方法 |
US4837342A (en) * | 1986-02-28 | 1989-06-06 | Sagami Chemical Research Center | Prostacyclin analogue, and blood circulation improving agent and anti-ulcer composition containing it as active ingredient |
-
1978
- 1978-01-26 IT IT7819616A patent/IT7819616A0/it unknown
-
1979
- 1979-01-23 ZA ZA79268A patent/ZA79268B/xx unknown
- 1979-01-23 CS CS804928A patent/CS215150B2/cs unknown
- 1979-01-23 CS CS79513A patent/CS215149B2/cs unknown
- 1979-01-25 HU HU79EA191A patent/HU182726B/hu not_active IP Right Cessation
- 1979-01-25 KR KR7900219A patent/KR840000948B1/ko active
- 1979-01-26 BE BE193094A patent/BE873731A/fr not_active IP Right Cessation
-
1980
- 1980-06-05 SU SU802930648A patent/SU1360582A3/ru active
-
1983
- 1983-04-28 AU AU14048/83A patent/AU556110B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
CS215149B2 (en) | 1982-07-30 |
KR830000687A (ko) | 1983-04-18 |
ZA79268B (en) | 1980-01-30 |
AU1404883A (en) | 1984-01-12 |
BE873731A (fr) | 1979-07-26 |
KR840000948B1 (ko) | 1984-07-01 |
SU1360582A3 (ru) | 1987-12-15 |
HU182726B (en) | 1984-03-28 |
AU556110B2 (en) | 1986-10-23 |
CS215150B2 (en) | 1982-07-30 |
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