BE872585A - Nouveaux derives de 4-amino-5-alkylsufonyl ortho-anisamides, leur procedes de preparation et leur application comme agents psychotropes - Google Patents

Nouveaux derives de 4-amino-5-alkylsufonyl ortho-anisamides, leur procedes de preparation et leur application comme agents psychotropes

Info

Publication number
BE872585A
BE872585A BE1009179A BE1009179A BE872585A BE 872585 A BE872585 A BE 872585A BE 1009179 A BE1009179 A BE 1009179A BE 1009179 A BE1009179 A BE 1009179A BE 872585 A BE872585 A BE 872585A
Authority
BE
Belgium
Prior art keywords
anisamides
alkylsufonyl
ortho
amino
preparation
Prior art date
Application number
BE1009179A
Other languages
English (en)
French (fr)
Inventor
M Thominet
J Acher
J C Monier
Original Assignee
Ile De France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ile De France filed Critical Ile De France
Publication of BE872585A publication Critical patent/BE872585A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
BE1009179A 1978-01-20 1978-12-07 Nouveaux derives de 4-amino-5-alkylsufonyl ortho-anisamides, leur procedes de preparation et leur application comme agents psychotropes BE872585A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7801632A FR2415099A1 (fr) 1978-01-20 1978-01-20 Nouveaux derives de 4-amino-5-alkylsulfonyl ortho-anisamides, leurs procedes de preparation et leur application comme psychotropes

Publications (1)

Publication Number Publication Date
BE872585A true BE872585A (fr) 1979-06-07

Family

ID=9203689

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1009179A BE872585A (fr) 1978-01-20 1978-12-07 Nouveaux derives de 4-amino-5-alkylsufonyl ortho-anisamides, leur procedes de preparation et leur application comme agents psychotropes

Country Status (42)

Country Link
US (2) US4294828A (no)
JP (1) JPS6049192B2 (no)
AR (2) AR221354A1 (no)
AT (1) AT377977B (no)
AU (1) AU528561B2 (no)
BE (1) BE872585A (no)
BG (2) BG31497A3 (no)
CA (1) CA1101430A (no)
CH (1) CH637927A5 (no)
CS (1) CS226181B2 (no)
CY (1) CY1201A (no)
DD (1) DD141520A5 (no)
DE (1) DE2901181C2 (no)
DK (1) DK158346C (no)
EG (1) EG14045A (no)
ES (2) ES476755A1 (no)
FI (1) FI71126C (no)
FR (1) FR2415099A1 (no)
GB (2) GB2012765B (no)
GR (1) GR64431B (no)
HK (1) HK12184A (no)
HU (1) HU179793B (no)
IE (1) IE47798B1 (no)
IL (1) IL56411A (no)
IN (1) IN150226B (no)
IT (1) IT1164655B (no)
LU (1) LU80786A1 (no)
MC (1) MC1232A1 (no)
MX (2) MX5793E (no)
NL (1) NL191707C (no)
NO (1) NO151320C (no)
NZ (1) NZ189378A (no)
OA (1) OA06156A (no)
PH (2) PH15725A (no)
PL (2) PL116532B1 (no)
PT (1) PT69068A (no)
RO (2) RO76393A (no)
SE (2) SE448874B (no)
SU (1) SU820659A3 (no)
YU (2) YU42172B (no)
ZA (1) ZA79219B (no)
ZM (1) ZM579A1 (no)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2440946A2 (fr) * 1978-01-20 1980-06-06 Ile De France Nouveaux benzamides heterocycliques substitues, leurs procedes de preparation et leur application comme modificateurs du comportement
NZ199080A (en) * 1980-12-12 1984-07-31 Beecham Group Ltd 2-alkoxy-4-amino-5-alkylsulphonyl-n-(3beta-(8-hydrocarbyl-8-azabicyclo (3,2,1)octyl))benzamides
FR2550447B1 (fr) * 1983-08-10 1986-01-17 Ile De France Application du n-(ally-2-pyrrolidinylmethyl) 2-methoxy 4-amino 5-methylsulfamoyl benzamide comme antiagregant plaquettaire
FR2574795B1 (fr) * 1984-12-18 1987-11-20 Ile De France Nouveau procede industriel de synthese du n-((1'-allyl 2'-pyrrolidinyl) methyl) 2-methoxy 4,5-azimido benzamide
FR2584401B1 (fr) * 1985-07-04 1987-11-20 Ile De France Nouveau benzamide, son procede de preparation et son application dans le domaine therapeutique
US5227388A (en) * 1989-12-26 1993-07-13 Hoechst-Roussel Pharmaceuticals Incorporated Thienobenzoxepins and naphthothiophenes
US5260319A (en) * 1989-12-26 1993-11-09 Hoechst-Roussel Pharmaceuticals Incorporated Thienobenzoxepins and naphthothiophenes
FR2678266A1 (fr) * 1991-06-28 1992-12-31 Delagrange Laboratoires Nouveaux derives de 2-hydroxy 4-amino 5-ethylsulfonyl benzamide utiles comme anxiolytiques.
FR2699533A1 (fr) * 1992-12-21 1994-06-24 Mouhtaram Mohamed Dérivés de N-((1,4-dialkyl-6-arylpipérazine-2-yl)méthyl)benzamides. (Isomères cis et trans) Propriétés pharmacologiques et applications.
FR2753376B1 (fr) * 1996-09-18 1998-10-16 Synthelabo Compositions pharmaceutiques comprenant de l'amisulpride et leurs applications therapeutiques
FR2762213B1 (fr) * 1997-04-18 1999-05-14 Synthelabo Composition pharmaceutique a retention gastrique
US6169094B1 (en) * 1998-07-14 2001-01-02 Sanofi-Synthelabo Compositions of (S) (-)-amisulpride
ATE445838T1 (de) 2001-07-25 2009-10-15 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
CA2525366A1 (en) * 2003-05-16 2004-11-25 Pfizer Products Inc. Therapeutic combinations of atypical antipsychotics with gaba modulators, anticonvulsants or benzodiazapines
FR2857263B1 (fr) * 2003-07-09 2005-09-09 Sanofi Synthelabo Nouvelle composition pharmaceutique solide comprenant de l'amisulpride
MXPA06013163A (es) * 2004-05-11 2007-02-13 Pfizer Prod Inc Combinacion de antipsicoticos atipicos y antagonistas del receptor 5-ht1b.
EP1879569A2 (en) * 2005-04-22 2008-01-23 Wyeth Therapeutic combinations for the treatment or prevention of psychotic disorders
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
WO2008036682A2 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
US7825156B2 (en) * 2007-02-02 2010-11-02 Copharms Method of treating bipolar depression with a benzamide derivative
JP2011526881A (ja) * 2008-06-25 2011-10-20 ファイザー・インク ジアリール化合物およびそれらの使用
US20100105755A1 (en) * 2008-09-12 2010-04-29 Auspex Pharmaceuticals, Inc. Substituted benzamide modulators of dopamine receptor
ES2728225T3 (es) 2009-02-20 2019-10-23 2 Bbb Medicines B V Sistema de administración de fármacos a base de glutatión
US8445002B2 (en) 2009-05-06 2013-05-21 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
CN101898991B (zh) * 2009-05-31 2013-09-25 江苏天士力帝益药业有限公司 一种(s)(-)-氨磺必利d-(-)-酒石酸盐的合成方法
CN101628886B (zh) * 2009-08-25 2012-12-12 北京紫萌同达科技有限公司 一种2-甲氧基-4-氨基-5-乙砜基苯甲酸的合成方法
GB201004020D0 (en) 2010-03-11 2010-04-21 Acacia Pharma Ltd New therapeutic use
AU2014202535B2 (en) * 2010-03-11 2016-05-26 Acacia Pharma Limited The use of amisulpride as an anti-emetic
AU2016216578B2 (en) * 2010-03-11 2017-11-23 Acacia Pharma Limited The use of amisulpride as an anti-emetic
US20130096319A1 (en) 2010-06-17 2013-04-18 Lupin Limited Process for preparation of amisulpride
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN103304453A (zh) * 2013-06-18 2013-09-18 苏州诚和医药化学有限公司 两步法合成2-甲氧基-4-氨基-5-乙砜基苯甲酸
CN103319384A (zh) * 2013-06-18 2013-09-25 苏州诚和医药化学有限公司 制备2-甲氧基-4-氨基-5-乙砜基苯甲酸的方法
CN103450058B (zh) * 2013-09-18 2015-10-14 广安凯特医药化工有限公司 一种氨磺必利酸的制备方法
CN104725292B (zh) * 2015-03-23 2017-07-25 湖北荆江源制药股份有限公司 一种(s)(‑)‑氨磺必利的制备方法
GB201618425D0 (en) * 2016-11-01 2016-12-14 Acacia Pharma Ltd method
JP6968899B2 (ja) * 2016-11-28 2021-11-17 エルビー・ファーマシューティカルズ・インコーポレイテッド 向精神薬およびその使用
US11377421B2 (en) 2016-11-28 2022-07-05 Lb Pharmaceuticals Inc. Psychotropic agents and uses thereof
CN106995397B (zh) * 2016-12-12 2020-01-14 河北医科大学 R-氨磺必利药用盐、制备方法、晶型及其用途
GB201702250D0 (en) 2017-02-10 2017-03-29 Acacia Pharma Ltd Method
MX2020005518A (es) 2017-12-05 2020-11-06 Sunovion Pharmaceuticals Inc Mezclas no racemicas y usos de las mismas.
JP2021505595A (ja) 2017-12-05 2021-02-18 サノビオン ファーマシューティカルズ インクＳｕｎｏｖｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． 結晶形およびその製造方法
CN110790693A (zh) * 2018-08-02 2020-02-14 北京万全德众医药生物技术有限公司 一种(s)(-)-氨磺必利的制备方法
JP2022535893A (ja) 2019-06-04 2022-08-10 サノビオン ファーマシューティカルズ インク 放出調節製剤およびその使用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
FR2313935A1 (fr) * 1975-06-10 1977-01-07 Ile De France Nouveaux benzamides substitues, leurs derives et leur procede de preparation
US3862139A (en) * 1972-06-23 1975-01-21 Delmar Chem Heterocyclic benzamide compounds
FR2244760B1 (no) * 1973-09-25 1980-06-27 Ile De France
FR2299862B1 (fr) * 1975-02-07 1978-07-21 Ile De France Nouveau
FR2294698A1 (fr) * 1974-12-18 1976-07-16 Synthelabo Nouveaux derives des methoxy-2 benzamides substitues, leurs sels, leur preparation et les medicaments qui en renferment
SE412908B (sv) * 1974-12-18 1980-03-24 Synthelabo Forfarande for framstellning av terapeutiskt aktiva 2-metoxibensamider innehallande en pyrrolidin- eller en piperidinrest

Also Published As

Publication number Publication date
CS226181B2 (en) 1984-03-19
RO80311A (ro) 1982-12-06
RO76393A (ro) 1981-03-30
NO151320C (no) 1985-04-17
GB2012765B (en) 1982-09-08
AU4337379A (en) 1979-07-26
AR221354A1 (es) 1981-01-30
YU5079A (en) 1983-06-30
US4294828A (en) 1981-10-13
MC1232A1 (fr) 1979-10-26
JPS6049192B2 (ja) 1985-10-31
ATA39879A (de) 1983-12-15
NL191707C (nl) 1996-04-02
PL212899A1 (no) 1980-01-14
IL56411A (en) 1982-09-30
US4401822A (en) 1983-08-30
SE460968B (sv) 1989-12-11
DE2901181A1 (de) 1979-07-26
NO790180L (no) 1979-07-23
SE8603773D0 (sv) 1986-09-09
SE448874B (sv) 1987-03-23
BG31496A3 (en) 1982-01-15
IT7947706A0 (it) 1979-01-18
HU179793B (en) 1982-12-28
FR2415099A1 (fr) 1979-08-17
EG14045A (en) 1983-09-30
FI790182A (fi) 1979-07-21
CY1201A (en) 1983-12-31
NZ189378A (en) 1983-03-15
ZA79219B (en) 1980-01-30
CA1101430A (en) 1981-05-19
FI71126B (fi) 1986-08-14
DK20979A (da) 1979-07-21
SE7900380L (sv) 1979-07-21
LU80786A1 (fr) 1979-09-07
NO151320B (no) 1984-12-10
NL191707B (nl) 1995-12-01
ZM579A1 (en) 1979-12-21
FR2415099B1 (no) 1981-02-20
GB2012765A (en) 1979-08-01
PH22287A (en) 1988-07-22
DK158346C (da) 1990-10-08
AU528561B2 (en) 1983-05-05
PL118151B1 (en) 1981-09-30
SE8603773L (sv) 1986-09-09
PT69068A (fr) 1979-02-01
HK12184A (en) 1984-02-24
CH637927A5 (fr) 1983-08-31
NL7900457A (nl) 1979-07-24
SU820659A3 (ru) 1981-04-07
BG31497A3 (en) 1982-01-15
JPS54145658A (en) 1979-11-14
YU41278B (en) 1986-12-31
DD141520A5 (de) 1980-05-07
AR220574A1 (es) 1980-11-14
DK158346B (da) 1990-05-07
PH15725A (en) 1983-03-18
GB2083458B (en) 1983-03-09
IE47798B1 (en) 1984-06-27
IL56411A0 (en) 1979-03-12
YU25483A (en) 1983-10-31
IT1164655B (it) 1987-04-15
MX5793E (es) 1984-07-19
MX7623E (es) 1990-03-27
FI71126C (fi) 1986-11-24
IN150226B (no) 1982-08-21
DE2901181C2 (de) 1984-07-19
OA06156A (fr) 1981-06-30
IE790092L (en) 1979-07-20
AT377977B (de) 1985-05-28
GR64431B (en) 1980-03-21
PL116532B1 (en) 1981-06-30
ES477782A1 (es) 1979-09-16
YU42172B (en) 1988-06-30
ES476755A1 (es) 1979-06-01
GB2083458A (en) 1982-03-24

Similar Documents

Publication Publication Date Title
BE872585A (fr) Nouveaux derives de 4-amino-5-alkylsufonyl ortho-anisamides, leur procedes de preparation et leur application comme agents psychotropes
FR2498188B1 (fr) Nouveaux derives de l'indole, leur preparation et leur application comme medicaments
BE873656A (fr) Nouveaux derives de la pyridine, leur preparation et leur utilisation
BE864632A (fr) Nouveaux derives d'acides phenoxy-alpha-phenoxy-alcanecarboxyliques, leur preparation et leur application comme herbicides
BE873766A (fr) Derives de la 2-pyrrolidone et leur preparation
MC1231A1 (fr) Nouveaux benzamides heterocycliques substitues,leurs procedes de preparation et leur application comme modificateurs du comportement
BE875846A (fr) Derives heterocycliques et leur preparation
BE865173A (fr) Nouvelles 1,3,4-thiadiazol-2-ylurées leur procédé de préparation et leur application comme fongicides
BE838244A (fr) Nouveaux derives du 4,4'-divinyl-stilbene utilisables comme azurants optiques et leur preparation
BE869261A (fr) Nouveaux derives de la pepstatine, leur preparation et les compositions qui les contiennent
BE853304A (fr) Nouveaux derives de 1,3,4,-thiadiazolyle, leur procede de preparation et leur application comme herbicides
FR2318153A1 (fr) Nouveaux ethers de 2',3,6'-trichloro-4-cyano-4'-benzoylureido-diphenyle, leur procede de preparation et leur application comme insecticides
BE869133A (fr) Nouveaux derives de l'indole, leur preparation et leur application comme medicaments
BE862663A (fr) Nouvelles phenylcarbamoyl-2-pyrazolines substituees, leur procede de preparation et leur application comme insecticides
BE857522A (fr) Nouveaux derives de 1-azolyl-4-hydroxybutane, leur procede de preparation et leur application comme fongicides et bactericides
BE878442A (fr) Derives de la n-phenyl-indoline, leur preparation et leur application comme medicaments
BE859480A (fr) Nouveaux derives de (1-phenyl-2-triazolyl-ethyl)-thioethers leur procede de preparation et leur application comme fongicides et substances de croissance
BE862097A (fr) Nouveaux benzothiophenes, leurs procedes de preparation et leur application notamment comme hypolipemiants et hypocholesterolemiants
BE869177A (fr) Derives halogenomethyles d'aminoacides, leur preparation et leur utilisation
BE875592A (fr) Derives de pyrrolidinecarboxaldehyde et de piperidinecarboxaldehyde et leur preparation
BE839711A (fr) Nouvelles 2,3-dihalogeno-alcanoyl-urees, leur procede de preparation et leur application comme fongicides
BE875013A (fr) Nouveaux derives de 2-hydroxymethyl-pyrazine, utiles notamment comme hypolipemiants, et leur procede de preparation
FR2337128A1 (fr) Nouveaux derives n-aminothio de n-methylcarbamates, leur procede de preparation et leur application comme pesticides
BE866718A (fr) Nouveaux derives d'acides azolylalcane-carboxyliques, leur procede de preparation et leur application comme fongicides
BE863802A (fr) Nouveaux derives d'everninomicine, leur procedes de preparation et compositions pharmaceutiques contenant lesdits derives

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SOC. D ETUDES SCIENTIFIQUES ET INDUSTRIELLES D

Effective date: 19891231

RR Patent reestablished after lapse

Free format text: 901001 *SOC. D *ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L ILE DEFRANCE

RE20 Patent expired

Owner name: SOC. D ETUDES SCIENTIFIQUES ET INDUSTRIELLES D

Effective date: 19981207