BE865182A - Derives de la morphine, leur procede de preparation et leur application comme medicament - Google Patents
Derives de la morphine, leur procede de preparation et leur application comme medicamentInfo
- Publication number
- BE865182A BE865182A BE186173A BE186173A BE865182A BE 865182 A BE865182 A BE 865182A BE 186173 A BE186173 A BE 186173A BE 186173 A BE186173 A BE 186173A BE 865182 A BE865182 A BE 865182A
- Authority
- BE
- Belgium
- Prior art keywords
- preparation
- application
- medicinal product
- morphine derivatives
- morphine
- Prior art date
Links
- 229940126601 medicinal product Drugs 0.000 title 1
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical class O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB12342/77A GB1587831A (en) | 1977-03-23 | 1977-03-23 | Morphine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE865182A true BE865182A (fr) | 1978-09-22 |
Family
ID=10002756
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE186173A BE865182A (fr) | 1977-03-23 | 1978-03-22 | Derives de la morphine, leur procede de preparation et leur application comme medicament |
Country Status (25)
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4362870A (en) * | 1980-01-16 | 1982-12-07 | Regents Of The University Of Minnesota | Selective opioid receptor alkylating agents |
| US4401672A (en) * | 1981-10-13 | 1983-08-30 | Regents Of The University Of Minnesota | Non-addictive narcotic antitussive preparation |
| EP0103636B1 (en) * | 1982-03-16 | 1990-09-12 | Rockefeller University | Use of opium antagonists for the manufacture of medicaments for controlling gastrointestinal dysmotility |
| GB8711558D0 (en) * | 1987-05-15 | 1987-06-17 | Reckitt & Colmann Prod Ltd | Derivative of codeine |
| AU666702B2 (en) * | 1992-01-23 | 1996-02-22 | Toray Industries, Inc. | Morphinan derivative and medicinal use |
| DE69414085T2 (de) * | 1993-07-19 | 1999-03-18 | Toray Industries, Inc., Tokio/Tokyo | Wirkstoff zum schutze von gehirnzellen |
| NZ268969A (en) * | 1993-07-23 | 1997-06-24 | Toray Industries | Morphinan derivatives and pharmaceutical compositions |
| US20060063792A1 (en) * | 2004-09-17 | 2006-03-23 | Adolor Corporation | Substituted morphinans and methods of their use |
| CN101198612A (zh) | 2005-06-16 | 2008-06-11 | 马林克罗特公司 | 通过1-卤代-蒂巴因或类似物制备14-羟基阿片类的合成路线 |
| US9969746B2 (en) | 2013-12-05 | 2018-05-15 | The University Of Bath | Opioid compounds and their uses |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3332950A (en) * | 1963-03-23 | 1967-07-25 | Endo Lab | 14-hydroxydihydronormorphinone derivatives |
| IL26896A (en) * | 1966-01-19 | 1970-11-30 | Endo Lab | 14 - Hydroxynormorphinins and 14 - Hydroxynormorphinones |
| BE788478A (fr) * | 1971-09-08 | 1973-03-06 | Bristol Myers Co | Procede de preparation de composes analgesiques |
| US4017497A (en) * | 1975-11-18 | 1977-04-12 | Bristol-Myers Company | Process for the preparation of 14-hydroxymorphinan derivatives |
-
1977
- 1977-03-23 GB GB12342/77A patent/GB1587831A/en not_active Expired
-
1978
- 1978-03-14 NZ NZ186693A patent/NZ186693A/xx unknown
- 1978-03-14 IE IE514/78A patent/IE46442B1/en not_active IP Right Cessation
- 1978-03-15 ZA ZA00781525A patent/ZA781525B/xx unknown
- 1978-03-15 US US05/886,834 patent/US4241067A/en not_active Expired - Lifetime
- 1978-03-21 HU HU78RE627A patent/HU177722B/hu unknown
- 1978-03-21 AU AU34356/78A patent/AU518614B2/en not_active Expired
- 1978-03-21 SU SU782595495A patent/SU856381A3/ru active
- 1978-03-22 JP JP3354578A patent/JPS53121798A/ja active Granted
- 1978-03-22 SE SE7803329A patent/SE436132B/sv not_active IP Right Cessation
- 1978-03-22 DD DD204355A patent/DD135081A5/xx unknown
- 1978-03-22 AT AT204378A patent/AT360664B/de not_active IP Right Cessation
- 1978-03-22 BE BE186173A patent/BE865182A/xx not_active IP Right Cessation
- 1978-03-22 CH CH315978A patent/CH630629A5/fr not_active IP Right Cessation
- 1978-03-22 NL NL7803084A patent/NL7803084A/xx not_active Application Discontinuation
- 1978-03-22 DE DE19782812581 patent/DE2812581A1/de not_active Ceased
- 1978-03-22 ES ES468170A patent/ES468170A1/es not_active Expired
- 1978-03-22 AR AR271520A patent/AR218296A1/es active
- 1978-03-22 CA CA299,533A patent/CA1089455A/en not_active Expired
- 1978-03-22 CS CS781847A patent/CS199522B2/cs unknown
- 1978-03-22 IT IT48545/78A patent/IT1105172B/it active
- 1978-03-22 PL PL1978205497A patent/PL111722B1/pl unknown
- 1978-03-22 FR FR7808405A patent/FR2384775A1/fr active Granted
- 1978-03-22 DK DK129978A patent/DK149753C/da not_active IP Right Cessation
- 1978-03-22 LU LU79295A patent/LU79295A1/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: RECKITT & COLMAN PRODUCTS LTD Effective date: 19930331 |