BE870709A - Derives nouveaux de 7-azabenzimidazol a chaines laterales basiques, procede pour leur preparation et application comme medicaments - Google Patents
Derives nouveaux de 7-azabenzimidazol a chaines laterales basiques, procede pour leur preparation et application comme medicamentsInfo
- Publication number
- BE870709A BE870709A BE6046611A BE6046611A BE870709A BE 870709 A BE870709 A BE 870709A BE 6046611 A BE6046611 A BE 6046611A BE 6046611 A BE6046611 A BE 6046611A BE 870709 A BE870709 A BE 870709A
- Authority
- BE
- Belgium
- Prior art keywords
- azabenzimidazol
- preparation
- application
- side chain
- basic side
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3991977 | 1977-09-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE870709A true BE870709A (fr) | 1979-03-22 |
Family
ID=10412196
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE6046611A BE870709A (fr) | 1977-09-26 | 1978-09-22 | Derives nouveaux de 7-azabenzimidazol a chaines laterales basiques, procede pour leur preparation et application comme medicaments |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4247556A (fr) |
| JP (1) | JPS5455595A (fr) |
| AR (1) | AR219948A1 (fr) |
| AT (1) | AT365188B (fr) |
| BE (1) | BE870709A (fr) |
| CA (1) | CA1103673A (fr) |
| DD (1) | DD139579A5 (fr) |
| DE (1) | DE2841209A1 (fr) |
| DK (1) | DK424678A (fr) |
| EG (1) | EG13604A (fr) |
| ES (1) | ES473201A1 (fr) |
| FI (1) | FI782909A (fr) |
| FR (1) | FR2404009A1 (fr) |
| IT (1) | IT7851230A0 (fr) |
| NL (1) | NL7809713A (fr) |
| NO (1) | NO783239L (fr) |
| PT (1) | PT68584A (fr) |
| SE (1) | SE7810050L (fr) |
| SU (1) | SU795478A3 (fr) |
| ZA (1) | ZA785430B (fr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR950001015B1 (ko) * | 1986-01-10 | 1995-02-07 | 닛뽕 케미화 가부시끼가이샤 | 술폭시드 유도체의 제조방법 |
| US4772600A (en) * | 1986-06-09 | 1988-09-20 | A. H. Robins Company, Inc. | Fused imidazoheterocyclic compounds and pharmaceutical compositions |
| CA2305370C (fr) | 1997-09-26 | 2006-11-28 | Gerald Mcmahon | Composes a base d'azabenzimidazole destines a la modulation d'une fonction de proteine kinase de serine/threonine |
| FR2832148B1 (fr) * | 2001-11-14 | 2004-05-21 | Oreal | Nouvelles bases d'oxydation 2,5-diaminopyridine utiles pour la teinture des fibres keratiniques |
| US20090281075A1 (en) * | 2006-02-17 | 2009-11-12 | Pharmacopeia, Inc. | Isomeric purinones and 1h-imidazopyridinones as pkc-theta inhibitors |
| US7989459B2 (en) | 2006-02-17 | 2011-08-02 | Pharmacopeia, Llc | Purinones and 1H-imidazopyridinones as PKC-theta inhibitors |
| US7902187B2 (en) | 2006-10-04 | 2011-03-08 | Wyeth Llc | 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression |
| US7915268B2 (en) | 2006-10-04 | 2011-03-29 | Wyeth Llc | 8-substituted 2-(benzimidazolyl)purine derivatives for immunosuppression |
| TW200831104A (en) | 2006-10-04 | 2008-08-01 | Pharmacopeia Inc | 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression |
| EP2970277B1 (fr) | 2013-03-15 | 2021-07-28 | Knopp Biosciences LLC | Imidazo(4,5-b) pyridine-2-yl amides en tant que d'activateurs du canal kv7 |
| WO2016040952A2 (fr) | 2014-09-12 | 2016-03-17 | Knopp Biosciences Llc | Benzoimidazol-1,2-yl amides en tant qu'activateurs du canal kv7 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3004978A (en) * | 1961-10-17 | Certain i-tert-amino lower alkyl | ||
| US2987518A (en) * | 1958-12-10 | 1961-06-06 | Ciba Pharmacentical Products I | Certain 1h [4, 5-c]-imidazopyridines |
| CH386438A (de) * | 1959-03-18 | 1965-01-15 | Ciba Geigy | Verfahren zur Herstellung neuer 7-Aza-benzimidazole |
| US3719683A (en) * | 1970-11-20 | 1973-03-06 | Ciba Geigy Corp | Imidazo(4,5-b)pyridines |
| US4002623A (en) * | 1974-08-07 | 1977-01-11 | Pfizer Inc. | Anti-inflammatory 1-[3-(dialkylamino)propyl]-2-acylaminobenzimidazoles and 2-acylamino-3-[3-(dialkylamino)-propyl]imidazo[4,5-b]pyridines |
| US4059584A (en) * | 1974-08-07 | 1977-11-22 | Pfizer | 2-Acylamino-3-[3-(dialkylamino)propyl]imidazo[4,5-b]pyridines |
| SE422799B (sv) * | 1975-05-28 | 1982-03-29 | Merck & Co Inc | Analogiforfarande for framstellning av 1,3-dihydroimidazo (4,5-b)pyridin-2-oner |
-
1978
- 1978-09-08 ES ES473201A patent/ES473201A1/es not_active Expired
- 1978-09-13 FR FR7826249A patent/FR2404009A1/fr active Granted
- 1978-09-19 SU SU782664732A patent/SU795478A3/ru active
- 1978-09-20 DD DD78207957A patent/DD139579A5/de unknown
- 1978-09-22 BE BE6046611A patent/BE870709A/fr unknown
- 1978-09-22 PT PT68584A patent/PT68584A/pt unknown
- 1978-09-22 DE DE19782841209 patent/DE2841209A1/de not_active Withdrawn
- 1978-09-25 CA CA312,055A patent/CA1103673A/fr not_active Expired
- 1978-09-25 NL NL7809713A patent/NL7809713A/xx not_active Application Discontinuation
- 1978-09-25 NO NO783239A patent/NO783239L/no unknown
- 1978-09-25 AT AT0690278A patent/AT365188B/de not_active IP Right Cessation
- 1978-09-25 AR AR273835A patent/AR219948A1/es active
- 1978-09-25 IT IT7851230A patent/IT7851230A0/it unknown
- 1978-09-25 ZA ZA00785430A patent/ZA785430B/xx unknown
- 1978-09-25 SE SE7810050A patent/SE7810050L/xx unknown
- 1978-09-25 DK DK424678A patent/DK424678A/da unknown
- 1978-09-25 FI FI782909A patent/FI782909A/fi unknown
- 1978-09-26 JP JP11753778A patent/JPS5455595A/ja active Pending
- 1978-09-26 EG EG576/78A patent/EG13604A/xx active
-
1979
- 1979-01-15 US US06/003,385 patent/US4247556A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DD139579A5 (de) | 1980-01-09 |
| US4247556A (en) | 1981-01-27 |
| CA1103673A (fr) | 1981-06-23 |
| DE2841209A1 (de) | 1979-04-05 |
| AT365188B (de) | 1981-12-28 |
| DK424678A (da) | 1979-03-27 |
| ZA785430B (en) | 1979-09-26 |
| FR2404009A1 (fr) | 1979-04-20 |
| IT7851230A0 (it) | 1978-09-25 |
| PT68584A (de) | 1978-10-01 |
| SU795478A3 (ru) | 1981-01-07 |
| ATA690278A (de) | 1981-05-15 |
| JPS5455595A (en) | 1979-05-02 |
| NL7809713A (nl) | 1979-03-28 |
| FR2404009B1 (fr) | 1981-09-18 |
| NO783239L (no) | 1979-03-27 |
| ES473201A1 (es) | 1979-03-16 |
| SE7810050L (sv) | 1979-03-27 |
| FI782909A (fi) | 1979-03-27 |
| AR219948A1 (es) | 1980-09-30 |
| EG13604A (en) | 1982-03-31 |
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