FR2344286A1 - Nouveaux derives 17-spirosultines, les g-hydroxy acides correspondants, leur procede de preparation et leur application comme medicament - Google Patents

Nouveaux derives 17-spirosultines, les g-hydroxy acides correspondants, leur procede de preparation et leur application comme medicament

Info

Publication number
FR2344286A1
FR2344286A1 FR7607476A FR7607476A FR2344286A1 FR 2344286 A1 FR2344286 A1 FR 2344286A1 FR 7607476 A FR7607476 A FR 7607476A FR 7607476 A FR7607476 A FR 7607476A FR 2344286 A1 FR2344286 A1 FR 2344286A1
Authority
FR
France
Prior art keywords
spirosultines
application
preparation process
hydroxy acids
medicinal product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7607476A
Other languages
English (en)
Other versions
FR2344286B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7607476A priority Critical patent/FR2344286A1/fr
Priority to US05/776,942 priority patent/US4093720A/en
Priority to BE175786A priority patent/BE852457A/fr
Priority to JP2767577A priority patent/JPS52136156A/ja
Priority to CH321077A priority patent/CH619718A5/fr
Priority to CA273,988A priority patent/CA1096857A/fr
Priority to DK112277AA priority patent/DK142681B/da
Priority to NL7702757A priority patent/NL7702757A/xx
Priority to DE19772711516 priority patent/DE2711516A1/de
Priority to GB11177/77A priority patent/GB1532734A/en
Publication of FR2344286A1 publication Critical patent/FR2344286A1/fr
Application granted granted Critical
Publication of FR2344286B1 publication Critical patent/FR2344286B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/007—3 membered carbocyclic rings in position 6-7
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/005—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
FR7607476A 1976-03-16 1976-03-16 Nouveaux derives 17-spirosultines, les g-hydroxy acides correspondants, leur procede de preparation et leur application comme medicament Granted FR2344286A1 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
FR7607476A FR2344286A1 (fr) 1976-03-16 1976-03-16 Nouveaux derives 17-spirosultines, les g-hydroxy acides correspondants, leur procede de preparation et leur application comme medicament
US05/776,942 US4093720A (en) 1976-03-16 1977-03-14 Novel-17-spirosultines their corresponding hydroxy acids and compositions thereof
JP2767577A JPS52136156A (en) 1976-03-16 1977-03-15 Production of novel 177 spirosultine derivatives and corresponding gammaa hydroxylic acid and pharmaceutical composition
CH321077A CH619718A5 (fr) 1976-03-16 1977-03-15
BE175786A BE852457A (fr) 1976-03-16 1977-03-15 Nouveaux derives 17-spirosultines
CA273,988A CA1096857A (fr) 1976-03-16 1977-03-15 PROCEDE DE PREPARATION DE NOUVEAUX DERIVES 17- SPIROSULTINES ET DES.gamma.-HYDROXY ACIDES
DK112277AA DK142681B (da) 1976-03-16 1977-03-15 Analogifremgangsmåde til fremstilling af 3-oxo-androst-4-en-17-spirosultiner.
NL7702757A NL7702757A (nl) 1976-03-16 1977-03-15 Werkwijze voor de bereiding van nieuwe 17-spirosultineverbindingen en overeenkomstige gam- ma-hydroxyzuren daarvan, werkwijze voor de bereiding van farmaceutische preparaten die deze stoffen bevat- ten, alsmede farmaceutische preparaten verkregen volgens deze werkwijze.
DE19772711516 DE2711516A1 (de) 1976-03-16 1977-03-16 Neue 17-spirosultin-derivate, die entsprechenden gamma-hydroxysaeuren, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
GB11177/77A GB1532734A (en) 1976-03-16 1977-03-16 17-spirosultine derivatives and the corresponding ypsilon-hydroxy-acid derivatives of androst-4-en-3-one processes for preparing them and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7607476A FR2344286A1 (fr) 1976-03-16 1976-03-16 Nouveaux derives 17-spirosultines, les g-hydroxy acides correspondants, leur procede de preparation et leur application comme medicament

Publications (2)

Publication Number Publication Date
FR2344286A1 true FR2344286A1 (fr) 1977-10-14
FR2344286B1 FR2344286B1 (fr) 1978-11-17

Family

ID=9170470

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7607476A Granted FR2344286A1 (fr) 1976-03-16 1976-03-16 Nouveaux derives 17-spirosultines, les g-hydroxy acides correspondants, leur procede de preparation et leur application comme medicament

Country Status (10)

Country Link
US (1) US4093720A (fr)
JP (1) JPS52136156A (fr)
BE (1) BE852457A (fr)
CA (1) CA1096857A (fr)
CH (1) CH619718A5 (fr)
DE (1) DE2711516A1 (fr)
DK (1) DK142681B (fr)
FR (1) FR2344286A1 (fr)
GB (1) GB1532734A (fr)
NL (1) NL7702757A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0176399A1 (fr) * 1984-08-24 1986-04-02 Roussel-Uclaf Nouveaux stéroides substitués en position 10 par un radical comportant une double ou triple liaison, leur procédé de préparation, leur application comme médicaments, les compositions pharmaceutiques les renfermant

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63193059U (fr) * 1987-05-30 1988-12-13
JPH02106265U (fr) * 1989-02-10 1990-08-23
FR2681069B1 (fr) * 1991-09-06 1995-04-28 Roussel Uclaf Nouveau procede de preparation de l'hydrocortisone et nouveaux intermediaires.
US6043235A (en) * 1999-07-21 2000-03-28 Research Triangle Institute 11β-aryl-17, 17-spirothiolane-substituted steroids

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2285137A1 (fr) * 1974-09-18 1976-04-16 Roussel Uclaf Nouveaux derives steroides 17-spirosultines, les g-hydroxyacides correspondants, leur procede de preparation et leur application comme medicament

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD80023A (fr) *
DE2264189C3 (de) * 1972-12-29 1979-05-31 Merck & Co., Inc., Rahway, N.J. (V.St.A.) 3'-(3-Oxo-17beta-hydroxy-6,7-methylen-androst-4en-bzw.-l,4-dien-17 a-yl) -propionsäureverbindungen, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Mittel

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2285137A1 (fr) * 1974-09-18 1976-04-16 Roussel Uclaf Nouveaux derives steroides 17-spirosultines, les g-hydroxyacides correspondants, leur procede de preparation et leur application comme medicament

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0176399A1 (fr) * 1984-08-24 1986-04-02 Roussel-Uclaf Nouveaux stéroides substitués en position 10 par un radical comportant une double ou triple liaison, leur procédé de préparation, leur application comme médicaments, les compositions pharmaceutiques les renfermant

Also Published As

Publication number Publication date
DK142681C (fr) 1981-08-03
FR2344286B1 (fr) 1978-11-17
JPS6126557B2 (fr) 1986-06-20
DK112277A (fr) 1977-09-17
DE2711516A1 (de) 1977-09-22
BE852457A (fr) 1977-09-15
DK142681B (da) 1980-12-15
CA1096857A (fr) 1981-03-03
JPS52136156A (en) 1977-11-14
GB1532734A (en) 1978-11-22
NL7702757A (nl) 1977-09-20
US4093720A (en) 1978-06-06
CH619718A5 (fr) 1980-10-15
DE2711516C2 (fr) 1987-03-05

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