JPS52136156A - Production of novel 177 spirosultine derivatives and corresponding gammaa hydroxylic acid and pharmaceutical composition - Google Patents

Production of novel 177 spirosultine derivatives and corresponding gammaa hydroxylic acid and pharmaceutical composition

Info

Publication number
JPS52136156A
JPS52136156A JP2767577A JP2767577A JPS52136156A JP S52136156 A JPS52136156 A JP S52136156A JP 2767577 A JP2767577 A JP 2767577A JP 2767577 A JP2767577 A JP 2767577A JP S52136156 A JPS52136156 A JP S52136156A
Authority
JP
Japan
Prior art keywords
spirosultine
gammaa
derivatives
novel
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2767577A
Other languages
English (en)
Other versions
JPS6126557B2 (ja
Inventor
Rusoo Jiyunubieebu
Toreri Besuberuto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of JPS52136156A publication Critical patent/JPS52136156A/ja
Publication of JPS6126557B2 publication Critical patent/JPS6126557B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/007—3 membered carbocyclic rings in position 6-7
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/005—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
JP2767577A 1976-03-16 1977-03-15 Production of novel 177 spirosultine derivatives and corresponding gammaa hydroxylic acid and pharmaceutical composition Granted JPS52136156A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7607476A FR2344286A1 (fr) 1976-03-16 1976-03-16 Nouveaux derives 17-spirosultines, les g-hydroxy acides correspondants, leur procede de preparation et leur application comme medicament

Publications (2)

Publication Number Publication Date
JPS52136156A true JPS52136156A (en) 1977-11-14
JPS6126557B2 JPS6126557B2 (ja) 1986-06-20

Family

ID=9170470

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2767577A Granted JPS52136156A (en) 1976-03-16 1977-03-15 Production of novel 177 spirosultine derivatives and corresponding gammaa hydroxylic acid and pharmaceutical composition

Country Status (10)

Country Link
US (1) US4093720A (ja)
JP (1) JPS52136156A (ja)
BE (1) BE852457A (ja)
CA (1) CA1096857A (ja)
CH (1) CH619718A5 (ja)
DE (1) DE2711516A1 (ja)
DK (1) DK142681B (ja)
FR (1) FR2344286A1 (ja)
GB (1) GB1532734A (ja)
NL (1) NL7702757A (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003531815A (ja) * 1999-07-21 2003-10-28 リサーチ・トライアングル・インスティチュート １１β−アリール−１７，１７−スピロチオラン置換ステロイド

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2569408B1 (fr) * 1984-08-24 1986-10-03 Roussel Uclaf Nouveaux steroides substitues en position 10 par un radical comportant une double ou triple liaison, leur procede de preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant
JPS63193059U (ja) * 1987-05-30 1988-12-13
JPH02106265U (ja) * 1989-02-10 1990-08-23
FR2681069B1 (fr) * 1991-09-06 1995-04-28 Roussel Uclaf Nouveau procede de preparation de l'hydrocortisone et nouveaux intermediaires.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD80023A (ja) *
DE2264189C3 (de) * 1972-12-29 1979-05-31 Merck & Co., Inc., Rahway, N.J. (V.St.A.) 3'-(3-Oxo-17beta-hydroxy-6,7-methylen-androst-4en-bzw.-l,4-dien-17 a-yl) -propionsäureverbindungen, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Mittel
FR2285137A1 (fr) * 1974-09-18 1976-04-16 Roussel Uclaf Nouveaux derives steroides 17-spirosultines, les g-hydroxyacides correspondants, leur procede de preparation et leur application comme medicament

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003531815A (ja) * 1999-07-21 2003-10-28 リサーチ・トライアングル・インスティチュート １１β−アリール−１７，１７−スピロチオラン置換ステロイド
JP4768181B2 (ja) * 1999-07-21 2011-09-07 リサーチ・トライアングル・インスティチュート １１β−アリール−１７，１７−スピロチオラン置換ステロイド

Also Published As

Publication number Publication date
DK142681C (ja) 1981-08-03
FR2344286B1 (ja) 1978-11-17
JPS6126557B2 (ja) 1986-06-20
DK112277A (ja) 1977-09-17
DE2711516A1 (de) 1977-09-22
BE852457A (fr) 1977-09-15
DK142681B (da) 1980-12-15
CA1096857A (fr) 1981-03-03
GB1532734A (en) 1978-11-22
NL7702757A (nl) 1977-09-20
FR2344286A1 (fr) 1977-10-14
US4093720A (en) 1978-06-06
CH619718A5 (ja) 1980-10-15
DE2711516C2 (ja) 1987-03-05

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