CH619718A5 - - Google Patents

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Publication number
CH619718A5
CH619718A5 CH321077A CH321077A CH619718A5 CH 619718 A5 CH619718 A5 CH 619718A5 CH 321077 A CH321077 A CH 321077A CH 321077 A CH321077 A CH 321077A CH 619718 A5 CH619718 A5 CH 619718A5
Authority
CH
Switzerland
Prior art keywords
formula
compound
action
diastereoisomers
subjects
Prior art date
Application number
CH321077A
Other languages
English (en)
French (fr)
Inventor
Genevieve Rousseau
Vesperto Torelli
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of CH619718A5 publication Critical patent/CH619718A5/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/007—3 membered carbocyclic rings in position 6-7
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/005—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
CH321077A 1976-03-16 1977-03-15 CH619718A5 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7607476A FR2344286A1 (fr) 1976-03-16 1976-03-16 Nouveaux derives 17-spirosultines, les g-hydroxy acides correspondants, leur procede de preparation et leur application comme medicament

Publications (1)

Publication Number Publication Date
CH619718A5 true CH619718A5 (ja) 1980-10-15

Family

ID=9170470

Family Applications (1)

Application Number Title Priority Date Filing Date
CH321077A CH619718A5 (ja) 1976-03-16 1977-03-15

Country Status (10)

Country Link
US (1) US4093720A (ja)
JP (1) JPS52136156A (ja)
BE (1) BE852457A (ja)
CA (1) CA1096857A (ja)
CH (1) CH619718A5 (ja)
DE (1) DE2711516C2 (ja)
DK (1) DK142681B (ja)
FR (1) FR2344286A1 (ja)
GB (1) GB1532734A (ja)
NL (1) NL7702757A (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2569408B1 (fr) * 1984-08-24 1986-10-03 Roussel Uclaf Nouveaux steroides substitues en position 10 par un radical comportant une double ou triple liaison, leur procede de preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant
JPS63193059U (ja) * 1987-05-30 1988-12-13
JPH02106265U (ja) * 1989-02-10 1990-08-23
FR2681069B1 (fr) * 1991-09-06 1995-04-28 Roussel Uclaf Nouveau procede de preparation de l'hydrocortisone et nouveaux intermediaires.
US6043235A (en) * 1999-07-21 2000-03-28 Research Triangle Institute 11β-aryl-17, 17-spirothiolane-substituted steroids
CN116925169A (zh) * 2023-07-20 2023-10-24 浙江朗华制药有限公司 一种甾体化合物及其制备方法以及在坎利酮和螺内酯杂质研究中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD80023A (ja) *
US3383282A (en) 1965-04-07 1968-05-14 Upjohn Co 7alpha-methyl-3, 5-androstadiene-3, 17-diols and pharmaceutically active compositions thereof
DE2264189C3 (de) * 1972-12-29 1979-05-31 Merck & Co., Inc., Rahway, N.J. (V.St.A.) 3'-(3-Oxo-17beta-hydroxy-6,7-methylen-androst-4en-bzw.-l,4-dien-17 a-yl) -propionsäureverbindungen, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Mittel
FR2216276B1 (ja) 1973-02-06 1976-11-05 Roussel Uclaf
FR2285137A1 (fr) * 1974-09-18 1976-04-16 Roussel Uclaf Nouveaux derives steroides 17-spirosultines, les g-hydroxyacides correspondants, leur procede de preparation et leur application comme medicament

Also Published As

Publication number Publication date
DE2711516C2 (de) 1987-03-05
DK142681B (da) 1980-12-15
CA1096857A (fr) 1981-03-03
FR2344286B1 (ja) 1978-11-17
US4093720A (en) 1978-06-06
JPS52136156A (en) 1977-11-14
BE852457A (fr) 1977-09-15
DE2711516A1 (de) 1977-09-22
NL7702757A (nl) 1977-09-20
DK142681C (ja) 1981-08-03
DK112277A (ja) 1977-09-17
JPS6126557B2 (ja) 1986-06-20
FR2344286A1 (fr) 1977-10-14
GB1532734A (en) 1978-11-22

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Legal Events

Date Code Title Description
PL Patent ceased