DK424678A - Fremgangsmaade til fremstilling af 7-azabenzimidazoler med basiske sidekaeder - Google Patents
Fremgangsmaade til fremstilling af 7-azabenzimidazoler med basiske sidekaederInfo
- Publication number
- DK424678A DK424678A DK424678A DK424678A DK424678A DK 424678 A DK424678 A DK 424678A DK 424678 A DK424678 A DK 424678A DK 424678 A DK424678 A DK 424678A DK 424678 A DK424678 A DK 424678A
- Authority
- DK
- Denmark
- Prior art keywords
- azabenzimidazoles
- procedure
- preparation
- side chains
- basic side
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3991977 | 1977-09-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK424678A true DK424678A (da) | 1979-03-27 |
Family
ID=10412196
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK424678A DK424678A (da) | 1977-09-26 | 1978-09-25 | Fremgangsmaade til fremstilling af 7-azabenzimidazoler med basiske sidekaeder |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4247556A (da) |
| JP (1) | JPS5455595A (da) |
| AR (1) | AR219948A1 (da) |
| AT (1) | AT365188B (da) |
| BE (1) | BE870709A (da) |
| CA (1) | CA1103673A (da) |
| DD (1) | DD139579A5 (da) |
| DE (1) | DE2841209A1 (da) |
| DK (1) | DK424678A (da) |
| EG (1) | EG13604A (da) |
| ES (1) | ES473201A1 (da) |
| FI (1) | FI782909A (da) |
| FR (1) | FR2404009A1 (da) |
| IT (1) | IT7851230A0 (da) |
| NL (1) | NL7809713A (da) |
| NO (1) | NO783239L (da) |
| PT (1) | PT68584A (da) |
| SE (1) | SE7810050L (da) |
| SU (1) | SU795478A3 (da) |
| ZA (1) | ZA785430B (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR950001015B1 (ko) * | 1986-01-10 | 1995-02-07 | 닛뽕 케미화 가부시끼가이샤 | 술폭시드 유도체의 제조방법 |
| US4772600A (en) * | 1986-06-09 | 1988-09-20 | A. H. Robins Company, Inc. | Fused imidazoheterocyclic compounds and pharmaceutical compositions |
| US6093728A (en) * | 1997-09-26 | 2000-07-25 | Asta Medica Aktiengesellschaft | Methods of modulating serine/threonine protein kinase function with azabenzimidazole-based compounds |
| FR2832148B1 (fr) * | 2001-11-14 | 2004-05-21 | Oreal | Nouvelles bases d'oxydation 2,5-diaminopyridine utiles pour la teinture des fibres keratiniques |
| US20090281075A1 (en) * | 2006-02-17 | 2009-11-12 | Pharmacopeia, Inc. | Isomeric purinones and 1h-imidazopyridinones as pkc-theta inhibitors |
| US7989459B2 (en) | 2006-02-17 | 2011-08-02 | Pharmacopeia, Llc | Purinones and 1H-imidazopyridinones as PKC-theta inhibitors |
| US7902187B2 (en) | 2006-10-04 | 2011-03-08 | Wyeth Llc | 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression |
| AR063142A1 (es) | 2006-10-04 | 2008-12-30 | Pharmacopeia Inc | Derivados de 2-(bencimidazolil) purina y purinonas 6-sustituidas utiles como inmunosupresores,y composiciones farmaceuticas que los contienen. |
| US7915268B2 (en) | 2006-10-04 | 2011-03-29 | Wyeth Llc | 8-substituted 2-(benzimidazolyl)purine derivatives for immunosuppression |
| ES2885424T3 (es) | 2013-03-15 | 2021-12-13 | Knopp Biosciences Llc | Imidazo(4,5-B)piridin-2-il amidas como activadores del canal Kv7 |
| US9481653B2 (en) | 2014-09-12 | 2016-11-01 | Knopp Biosciences Llc | Benzoimidazol-1,2-yl amides as Kv7 channel activators |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3004978A (en) * | 1961-10-17 | Certain i-tert-amino lower alkyl | ||
| US2987518A (en) * | 1958-12-10 | 1961-06-06 | Ciba Pharmacentical Products I | Certain 1h [4, 5-c]-imidazopyridines |
| CH386438A (de) * | 1959-03-18 | 1965-01-15 | Ciba Geigy | Verfahren zur Herstellung neuer 7-Aza-benzimidazole |
| US3719683A (en) * | 1970-11-20 | 1973-03-06 | Ciba Geigy Corp | Imidazo(4,5-b)pyridines |
| US4002623A (en) * | 1974-08-07 | 1977-01-11 | Pfizer Inc. | Anti-inflammatory 1-[3-(dialkylamino)propyl]-2-acylaminobenzimidazoles and 2-acylamino-3-[3-(dialkylamino)-propyl]imidazo[4,5-b]pyridines |
| US4059584A (en) * | 1974-08-07 | 1977-11-22 | Pfizer | 2-Acylamino-3-[3-(dialkylamino)propyl]imidazo[4,5-b]pyridines |
| SE422799B (sv) * | 1975-05-28 | 1982-03-29 | Merck & Co Inc | Analogiforfarande for framstellning av 1,3-dihydroimidazo (4,5-b)pyridin-2-oner |
-
1978
- 1978-09-08 ES ES473201A patent/ES473201A1/es not_active Expired
- 1978-09-13 FR FR7826249A patent/FR2404009A1/fr active Granted
- 1978-09-19 SU SU782664732A patent/SU795478A3/ru active
- 1978-09-20 DD DD78207957A patent/DD139579A5/de unknown
- 1978-09-22 BE BE6046611A patent/BE870709A/xx unknown
- 1978-09-22 DE DE19782841209 patent/DE2841209A1/de not_active Withdrawn
- 1978-09-22 PT PT68584A patent/PT68584A/pt unknown
- 1978-09-25 SE SE7810050A patent/SE7810050L/xx unknown
- 1978-09-25 IT IT7851230A patent/IT7851230A0/it unknown
- 1978-09-25 FI FI782909A patent/FI782909A/fi unknown
- 1978-09-25 NO NO783239A patent/NO783239L/no unknown
- 1978-09-25 AR AR273835A patent/AR219948A1/es active
- 1978-09-25 CA CA312,055A patent/CA1103673A/en not_active Expired
- 1978-09-25 AT AT0690278A patent/AT365188B/de not_active IP Right Cessation
- 1978-09-25 DK DK424678A patent/DK424678A/da unknown
- 1978-09-25 ZA ZA00785430A patent/ZA785430B/xx unknown
- 1978-09-25 NL NL7809713A patent/NL7809713A/xx not_active Application Discontinuation
- 1978-09-26 JP JP11753778A patent/JPS5455595A/ja active Pending
- 1978-09-26 EG EG576/78A patent/EG13604A/xx active
-
1979
- 1979-01-15 US US06/003,385 patent/US4247556A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NO783239L (no) | 1979-03-27 |
| EG13604A (en) | 1982-03-31 |
| FR2404009B1 (da) | 1981-09-18 |
| SU795478A3 (ru) | 1981-01-07 |
| NL7809713A (nl) | 1979-03-28 |
| PT68584A (de) | 1978-10-01 |
| SE7810050L (sv) | 1979-03-27 |
| AR219948A1 (es) | 1980-09-30 |
| DD139579A5 (de) | 1980-01-09 |
| ZA785430B (en) | 1979-09-26 |
| AT365188B (de) | 1981-12-28 |
| US4247556A (en) | 1981-01-27 |
| DE2841209A1 (de) | 1979-04-05 |
| ES473201A1 (es) | 1979-03-16 |
| FI782909A (fi) | 1979-03-27 |
| IT7851230A0 (it) | 1978-09-25 |
| BE870709A (fr) | 1979-03-22 |
| CA1103673A (en) | 1981-06-23 |
| JPS5455595A (en) | 1979-05-02 |
| ATA690278A (de) | 1981-05-15 |
| FR2404009A1 (fr) | 1979-04-20 |
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