DK129978A - Fremgangsmaade til fremstilling af morfinderivater - Google Patents

Fremgangsmaade til fremstilling af morfinderivater

Info

Publication number
DK129978A
DK129978A DK129978A DK129978A DK129978A DK 129978 A DK129978 A DK 129978A DK 129978 A DK129978 A DK 129978A DK 129978 A DK129978 A DK 129978A DK 129978 A DK129978 A DK 129978A
Authority
DK
Denmark
Prior art keywords
procedure
morphine derivatives
preparing
preparing morphine
derivatives
Prior art date
Application number
DK129978A
Other languages
English (en)
Other versions
DK149753C (da
DK149753B (da
Inventor
R J Kobylecki
G W Kirby
I G Guest
J W Lewis
Original Assignee
Reckitt & Colmann Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reckitt & Colmann Prod Ltd filed Critical Reckitt & Colmann Prod Ltd
Publication of DK129978A publication Critical patent/DK129978A/da
Publication of DK149753B publication Critical patent/DK149753B/da
Application granted granted Critical
Publication of DK149753C publication Critical patent/DK149753C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
DK129978A 1977-03-23 1978-03-22 Analogifremgangsmaade til fremstilling af morfinderivater DK149753C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1234277 1977-03-23
GB12342/77A GB1587831A (en) 1977-03-23 1977-03-23 Morphine derivatives

Publications (3)

Publication Number Publication Date
DK129978A true DK129978A (da) 1978-09-24
DK149753B DK149753B (da) 1986-09-22
DK149753C DK149753C (da) 1987-07-06

Family

ID=10002756

Family Applications (1)

Application Number Title Priority Date Filing Date
DK129978A DK149753C (da) 1977-03-23 1978-03-22 Analogifremgangsmaade til fremstilling af morfinderivater

Country Status (25)

Country Link
US (1) US4241067A (da)
JP (1) JPS53121798A (da)
AR (1) AR218296A1 (da)
AT (1) AT360664B (da)
AU (1) AU518614B2 (da)
BE (1) BE865182A (da)
CA (1) CA1089455A (da)
CH (1) CH630629A5 (da)
CS (1) CS199522B2 (da)
DD (1) DD135081A5 (da)
DE (1) DE2812581A1 (da)
DK (1) DK149753C (da)
ES (1) ES468170A1 (da)
FR (1) FR2384775A1 (da)
GB (1) GB1587831A (da)
HU (1) HU177722B (da)
IE (1) IE46442B1 (da)
IT (1) IT1105172B (da)
LU (1) LU79295A1 (da)
NL (1) NL7803084A (da)
NZ (1) NZ186693A (da)
PL (1) PL111722B1 (da)
SE (1) SE436132B (da)
SU (1) SU856381A3 (da)
ZA (1) ZA781525B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4362870A (en) * 1980-01-16 1982-12-07 Regents Of The University Of Minnesota Selective opioid receptor alkylating agents
US4401672A (en) * 1981-10-13 1983-08-30 Regents Of The University Of Minnesota Non-addictive narcotic antitussive preparation
EP0103636B1 (en) * 1982-03-16 1990-09-12 Rockefeller University Use of opium antagonists for the manufacture of medicaments for controlling gastrointestinal dysmotility
GB8711558D0 (en) * 1987-05-15 1987-06-17 Reckitt & Colmann Prod Ltd Derivative of codeine
WO1993015081A1 (fr) 1992-01-23 1993-08-05 Toray Industries, Inc. Derive de morphinane et utilisation en medicine
JP3948026B2 (ja) * 1993-07-19 2007-07-25 東レ株式会社 脳細胞保護剤
JP3843456B2 (ja) * 1993-07-23 2006-11-08 東レ株式会社 モルヒナン誘導体および医薬用途
US20060063792A1 (en) * 2004-09-17 2006-03-23 Adolor Corporation Substituted morphinans and methods of their use
CA2610859C (en) 2005-06-16 2013-11-12 Peter Xianqi Wang A synthetic route to 14-hydroxyl opiates through 1-halo-thebaine or analogs
ES2784690T3 (es) 2013-12-05 2020-09-29 Univ Bath Nuevos compuestos opioides y sus usos

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3332950A (en) * 1963-03-23 1967-07-25 Endo Lab 14-hydroxydihydronormorphinone derivatives
IL26896A (en) * 1966-01-19 1970-11-30 Endo Lab 14 - Hydroxynormorphinins and 14 - Hydroxynormorphinones
BE788478A (fr) * 1971-09-08 1973-03-06 Bristol Myers Co Procede de preparation de composes analgesiques
US4017497A (en) * 1975-11-18 1977-04-12 Bristol-Myers Company Process for the preparation of 14-hydroxymorphinan derivatives

Also Published As

Publication number Publication date
AT360664B (de) 1981-01-26
BE865182A (fr) 1978-09-22
US4241067A (en) 1980-12-23
HU177722B (en) 1981-12-28
PL111722B1 (en) 1980-09-30
AU3435678A (en) 1979-09-27
NZ186693A (en) 1979-10-25
IT1105172B (it) 1985-10-28
GB1587831A (en) 1981-04-08
SE436132B (sv) 1984-11-12
FR2384775A1 (fr) 1978-10-20
IE46442B1 (en) 1983-06-15
NL7803084A (nl) 1978-09-26
CS199522B2 (en) 1980-07-31
CA1089455A (en) 1980-11-11
SU856381A3 (ru) 1981-08-15
AU518614B2 (en) 1981-10-08
PL205497A1 (pl) 1979-06-04
ATA204378A (de) 1980-06-15
IE780514L (en) 1978-09-23
JPS53121798A (en) 1978-10-24
DD135081A5 (de) 1979-04-11
AR218296A1 (es) 1980-05-30
ZA781525B (en) 1979-04-25
ES468170A1 (es) 1979-01-01
DK149753C (da) 1987-07-06
DE2812581A1 (de) 1978-09-28
IT7848545A0 (it) 1978-03-22
SE7803329L (sv) 1978-09-24
FR2384775B1 (da) 1981-04-30
CH630629A5 (fr) 1982-06-30
JPS6259112B2 (da) 1987-12-09
LU79295A1 (fr) 1979-10-29
DK149753B (da) 1986-09-22

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