BE781878A - Nouveaux esters dissymetriques d'acides 1,4-dihydropyridine-dicarboxyliques, leur procede de preparation et leur application comme medicament - Google Patents

Nouveaux esters dissymetriques d'acides 1,4-dihydropyridine-dicarboxyliques, leur procede de preparation et leur application comme medicament

Info

Publication number
BE781878A
BE781878A BE781878A BE781878A BE781878A BE 781878 A BE781878 A BE 781878A BE 781878 A BE781878 A BE 781878A BE 781878 A BE781878 A BE 781878A BE 781878 A BE781878 A BE 781878A
Authority
BE
Belgium
Prior art keywords
dissymetric
dihydropyridine
esters
new
application
Prior art date
Application number
BE781878A
Other languages
English (en)
French (fr)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=5804433&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BE781878(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of BE781878A publication Critical patent/BE781878A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring (AREA)
BE781878A 1971-04-10 1972-04-10 Nouveaux esters dissymetriques d'acides 1,4-dihydropyridine-dicarboxyliques, leur procede de preparation et leur application comme medicament BE781878A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2117571A DE2117571C3 (de) 1971-04-10 1971-04-10 Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
BE781878A true BE781878A (fr) 1972-10-10

Family

ID=5804433

Family Applications (1)

Application Number Title Priority Date Filing Date
BE781878A BE781878A (fr) 1971-04-10 1972-04-10 Nouveaux esters dissymetriques d'acides 1,4-dihydropyridine-dicarboxyliques, leur procede de preparation et leur application comme medicament

Country Status (28)

Country Link
US (1) US3799934A (es)
JP (1) JPS5529989B1 (es)
AT (1) AT316551B (es)
AU (1) AU464663B2 (es)
BE (1) BE781878A (es)
BG (1) BG22818A3 (es)
CA (1) CA921035A (es)
CH (1) CH567472A5 (es)
CS (1) CS175429B2 (es)
DD (2) DD102077A5 (es)
DE (1) DE2117571C3 (es)
DK (1) DK132496C (es)
ES (1) ES401614A1 (es)
FI (1) FI55186C (es)
FR (1) FR2132830B1 (es)
GB (1) GB1358951A (es)
HK (1) HK18877A (es)
HU (1) HU164705B (es)
IE (1) IE36265B1 (es)
IL (1) IL39171A (es)
LU (1) LU65138A1 (es)
NL (1) NL164031C (es)
NO (1) NO135589C (es)
PL (1) PL84499B1 (es)
RO (2) RO60479A (es)
SE (1) SE371823B (es)
SU (1) SU435612A3 (es)
ZA (1) ZA722348B (es)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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US4001258A (en) * 1972-03-06 1977-01-04 Bayer Aktiengesellschaft 2-amino-1,4-dihydropyridine derivatives
US3917622A (en) * 1972-03-06 1975-11-04 Bayer Ag 2-Amino-1,4-dihydropyridine derivatives
US3917619A (en) * 1972-03-06 1975-11-04 Bayer Ag 2-Amino-4,5-dihydropyridine derivatives
DE2210674C3 (de) * 1972-03-06 1981-09-24 Bayer Ag, 5090 Leverkusen 2-Amino-6-methyl-1,4-dihydropyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
US3919246A (en) * 1972-03-06 1975-11-11 Bayer Ag Process for preparing 2-amino-1,4-dihydropyridine derivates
DD106832A5 (es) * 1972-03-06 1974-07-05
DE2218644C3 (de) * 1972-04-18 1982-08-19 Bayer Ag, 5090 Leverkusen Basische Ester von 1,4-Dihydropyridinen, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
US3989708A (en) * 1972-08-31 1976-11-02 Bayer Aktiengesellschaft 2-Amino-1,4-dihydropyridine derivatives
DE2242786A1 (de) * 1972-08-31 1974-03-14 Bayer Ag Verfahren zur herstellung von neuen 2-amino-1,4-dihydropyridinen mit einer carbonylfunktion sowie ihre verwendung als arzneimittel
DE2248150A1 (de) * 1972-09-30 1974-04-04 Bayer Ag Dihydropyridinpolyester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
GB1409865A (en) * 1973-02-13 1975-10-15 Science Union & Cie Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them
CH607848A5 (es) * 1974-06-04 1978-11-30 Bayer Ag
DE2508181A1 (de) * 1975-02-26 1976-09-09 Bayer Ag 1,4-dihydropyridincarbonsaeurearal- kylester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
FR2320750A1 (fr) * 1975-08-12 1977-03-11 Hexachimie Dihydro-1,4 pyridines et leur application therapeutique
US4154839A (en) * 1975-11-05 1979-05-15 Bayer Aktiengesellschaft 2,6-Dimethyl-3-carboxymethoxy-4-(2-nitrophenyl)-5-carbisobutoxy-1,4-dihydropyridine
DE2549568C3 (de) * 1975-11-05 1981-10-29 Bayer Ag, 5090 Leverkusen 2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel
DE2650013C3 (de) * 1976-10-30 1981-04-02 Bayer Ag, 5090 Leverkusen 1.4-Dihydro-2.6-dimethyl-4-(3-nitrophenyl)-3.5-pyridindicarbonsäureisopropyl-(2-propoxy-äthyl)-ester, Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel
DE2658183A1 (de) * 1976-12-22 1978-07-06 Bayer Ag In 2-position substituierte 1,4- dihydropyridin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
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DE2815578C2 (de) * 1978-04-11 1986-01-16 Bayer Ag, 5090 Leverkusen Neue pharmazeutische Verwendung von Nimodipin
SE429652B (sv) * 1978-06-30 1983-09-19 Haessle Ab 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester
DE2837477A1 (de) * 1978-08-28 1980-03-13 Bayer Ag Sila-substituierte 1,4-dihydropyridin- derivate
DE2841667A1 (de) * 1978-09-25 1980-04-10 Bayer Ag Fluorhaltige 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2949464A1 (de) * 1978-12-18 1980-06-26 Sandoz Ag Benzoxadiazole und benzothiadiazole, ihre herstellung und verwendung
DE2927933A1 (de) * 1979-07-11 1981-02-05 Hoechst Ag Acetylacetoxyalkyl-allyl-ether, ihre herstellung und verwendung
DE2935451A1 (de) * 1979-09-01 1981-03-19 Bayer Ag, 5090 Leverkusen Optisch aktive 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arneimittel
DE3023820A1 (de) * 1980-06-25 1982-01-14 Bayer Ag, 5090 Leverkusen 4,4-disubstituierte spiro-1,4-dihydropyridine, ein verfahren zu ihrer herstellung, sowie ihre verwendung als zwischenprodukt
DE3042769A1 (de) * 1980-11-13 1982-06-09 Bayer Ag, 5090 Leverkusen C-3 verknuepfte 1,4-dihydropyridine, ihre verwendung in arzneimitteln und verfahren zu ihrer herstellung
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US4321384A (en) * 1981-02-27 1982-03-23 American Home Products Corporation Antihypertensive agents
DE3130041A1 (de) * 1981-07-30 1983-02-17 Bayer Ag, 5090 Leverkusen Dihydropyridine mit positiv inotroper wirkung, neue verbindungen, ihre verwendung in arzneimitteln und verfahren zu ihrer herstellung
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
MX7567E (es) * 1981-12-23 1989-10-27 Yamanouchi Pharma Co Ltd Procedimiento para recubrir nicardipina de accion prolongada
JPS58159490A (ja) * 1982-02-23 1983-09-21 Nikken Kagaku Kk １，４−ジヒドロピリジン化合物
DE3208628A1 (de) * 1982-03-10 1983-09-22 Bayer Ag, 5090 Leverkusen Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3212736A1 (de) * 1982-04-06 1983-10-13 Bayer Ag, 5090 Leverkusen Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung
DE3222367A1 (de) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung
US4656181A (en) * 1982-11-24 1987-04-07 Cermol S.A. Esters of 1,4-dihydropyridines, processes for the preparation of the new esters, and medicaments containing the same
DE3248548A1 (de) * 1982-12-29 1984-07-05 Heinrich Mack Nachf., 7918 Illertissen Acylderivate von 1,4:3,6-dianhydro-hexiten, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3316510A1 (de) * 1983-05-06 1984-11-08 Bayer Ag Parenterale formulierung von nimodipin, ein verfahren zu ihrer herstellung sowie ihre verwendung bei der bekaempfung von erkrankungen
GB8314744D0 (en) * 1983-05-27 1983-07-06 Fujisawa Pharmaceutical Co 2 6-disubstituted-1 4-dihydropyridine derivative
IE57810B1 (en) * 1984-03-27 1993-04-21 Delagrange Lab 1,4-dihydropyridine derivatives,their preparation and their use
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US4794111A (en) * 1984-05-23 1988-12-27 Bayer Aktiengesellschaft Dihydropyridine preparations containing β-blockers
DE3419131A1 (de) * 1984-05-23 1985-11-28 Bayer Ag, 5090 Leverkusen Dihydropyridinkombinationspraeparate und verfahren zu ihrer herstellung
US4757071A (en) * 1984-12-14 1988-07-12 Nisshin Flour Milling Co., Ltd. 1,4-dihydropyridine derivatives, and pharmaceutical compositions containing same, useful for treating cardiovascular diseases
DE3542794A1 (de) * 1985-12-04 1987-06-11 Bayer Ag Antihypertensives kombinationspraeparat
US4771057A (en) * 1986-02-03 1988-09-13 University Of Alberta Reduced pyridyl derivatives with cardiovascular regulating properties
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DE3741540A1 (de) * 1987-12-08 1989-06-22 Bayer Ag Verfahren zur herstellung von unsymmetrischen dihydropyridinen
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Also Published As

Publication number Publication date
IE36265B1 (en) 1976-09-29
HK18877A (en) 1977-04-29
CS175429B2 (es) 1977-05-31
ES401614A1 (es) 1975-11-01
JPS5529989B1 (es) 1980-08-07
NO135589C (es) 1977-04-27
PL84499B1 (es) 1976-04-30
FR2132830B1 (es) 1975-12-26
HU164705B (es) 1974-04-11
ZA722348B (en) 1972-12-27
FI55186C (fi) 1979-06-11
IL39171A0 (en) 1972-07-26
BG22818A3 (es) 1977-04-20
DD102077A5 (es) 1973-12-05
IE36265L (en) 1972-10-10
FI55186B (fi) 1979-02-28
SU435612A3 (ru) 1974-07-05
AU464663B2 (en) 1975-08-18
NL164031B (nl) 1980-06-16
LU65138A1 (es) 1972-07-12
DK132496B (da) 1975-12-15
DK132496C (da) 1976-05-24
DD99371A5 (es) 1973-08-05
RO62643A (fr) 1978-05-15
IL39171A (en) 1975-04-25
GB1358951A (en) 1974-07-03
US3799934A (en) 1974-03-26
AU4045572A (en) 1973-10-04
NO135589B (es) 1977-01-17
NL164031C (nl) 1980-11-17
DE2117571C3 (de) 1979-10-11
FR2132830A1 (es) 1972-11-24
AT316551B (de) 1974-07-25
DE2117571A1 (de) 1972-10-19
SE371823B (es) 1974-12-02
DE2117571B2 (de) 1979-01-11
NL7204693A (es) 1972-10-12
RO60479A (es) 1976-08-15
CA921035A (en) 1973-02-13
CH567472A5 (es) 1975-10-15

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