FR2314714A1 - Acides et esters thenoylacetiques substitues, leur procede de preparation et leur utilisation comme medicaments hypolipidemiants - Google Patents

Acides et esters thenoylacetiques substitues, leur procede de preparation et leur utilisation comme medicaments hypolipidemiants

Info

Publication number
FR2314714A1
FR2314714A1 FR7618133A FR7618133A FR2314714A1 FR 2314714 A1 FR2314714 A1 FR 2314714A1 FR 7618133 A FR7618133 A FR 7618133A FR 7618133 A FR7618133 A FR 7618133A FR 2314714 A1 FR2314714 A1 FR 2314714A1
Authority
FR
France
Prior art keywords
thenoylacetic
hypolipidemating
substitute
esters
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7618133A
Other languages
English (en)
Other versions
FR2314714B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richardson Vicks Inc
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of FR2314714A1 publication Critical patent/FR2314714A1/fr
Application granted granted Critical
Publication of FR2314714B1 publication Critical patent/FR2314714B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/32—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
FR7618133A 1975-06-16 1976-06-15 Acides et esters thenoylacetiques substitues, leur procede de preparation et leur utilisation comme medicaments hypolipidemiants Granted FR2314714A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/587,117 US4032647A (en) 1975-06-16 1975-06-16 Substituted thenoylacetic acid and esters

Publications (2)

Publication Number Publication Date
FR2314714A1 true FR2314714A1 (fr) 1977-01-14
FR2314714B1 FR2314714B1 (fr) 1978-10-20

Family

ID=24348430

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7618133A Granted FR2314714A1 (fr) 1975-06-16 1976-06-15 Acides et esters thenoylacetiques substitues, leur procede de preparation et leur utilisation comme medicaments hypolipidemiants

Country Status (13)

Country Link
US (1) US4032647A (fr)
JP (1) JPS52258A (fr)
AU (1) AU497833B2 (fr)
BE (1) BE842969A (fr)
CA (1) CA1078853A (fr)
DE (1) DE2626385A1 (fr)
ES (1) ES448667A1 (fr)
FR (1) FR2314714A1 (fr)
GB (1) GB1496307A (fr)
NL (1) NL7605837A (fr)
PH (1) PH13873A (fr)
PT (1) PT65104B (fr)
ZA (1) ZA762789B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8525356D0 (en) * 1985-10-15 1985-11-20 Black & Decker Inc Obtaining fixing in wall
US5665874A (en) * 1989-01-17 1997-09-09 John Hopkins University Cancer related antigen
US5759837A (en) * 1989-01-17 1998-06-02 John Hopkins University Chemotherapy for cancer by inhibiting the fatty acid biosynthetic pathway
US5759791A (en) * 1989-01-17 1998-06-02 The Johns Hopkins University Cancer related antigen
US5614551A (en) * 1994-01-24 1997-03-25 The Johns Hopkins University Inhibitors of fatty acid synthesis as antimicrobial agents
US5981575A (en) * 1996-11-15 1999-11-09 Johns Hopkins University, The Inhibition of fatty acid synthase as a means to reduce adipocyte mass

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2223031A1 (fr) * 1973-04-02 1974-10-25 Richardson Merrell Inc

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2126597A1 (de) * 1971-05-28 1972-12-14 Farbwerke Hoechst AG, vormals, Meister Lucius & Brüning, 6000 Frankfurt Aminothiophencarbonsäureester und Verfahren zu ihrer Herstellung

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2223031A1 (fr) * 1973-04-02 1974-10-25 Richardson Merrell Inc

Also Published As

Publication number Publication date
ES448667A1 (es) 1977-07-01
BE842969A (fr) 1976-10-01
PT65104B (en) 1977-09-14
AU1368676A (en) 1977-11-10
GB1496307A (en) 1977-12-30
PT65104A (en) 1976-06-01
US4032647A (en) 1977-06-28
PH13873A (en) 1980-10-24
ZA762789B (en) 1977-04-27
AU497833B2 (en) 1979-01-11
CA1078853A (fr) 1980-06-03
FR2314714B1 (fr) 1978-10-20
DE2626385A1 (de) 1976-12-30
JPS52258A (en) 1977-01-05
NL7605837A (nl) 1976-12-20

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Legal Events

Date Code Title Description
ST Notification of lapse