BE2015C015I2 - - Google Patents
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- Publication number
- BE2015C015I2 BE2015C015I2 BE2015C015C BE2015C015C BE2015C015I2 BE 2015C015 I2 BE2015C015 I2 BE 2015C015I2 BE 2015C015 C BE2015C015 C BE 2015C015C BE 2015C015 C BE2015C015 C BE 2015C015C BE 2015C015 I2 BE2015C015 I2 BE 2015C015I2
- Authority
- BE
- Belgium
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C15/00—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts
- C07C15/02—Monocyclic hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/11—Aldehydes
- A61K31/115—Formaldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/001—Acyclic or carbocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/78—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C217/80—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63669604P | 2004-12-17 | 2004-12-17 | |
| US68639505P | 2005-06-02 | 2005-06-02 | |
| EP05854410A EP1841465A4 (en) | 2004-12-17 | 2005-12-19 | STYLENE DERIVATIVES AND THEIR USE OF THE BINDING AND IMAGE DISPLAY OF AMYLOID PLAQUE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE2015C015I2 true BE2015C015I2 (pm) | 2025-04-29 |
Family
ID=36588603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE2015C015C BE2015C015I2 (pm) | 2004-12-17 | 2015-03-10 |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US7807135B2 (pm) |
| EP (3) | EP2213652B1 (pm) |
| JP (1) | JP5128956B2 (pm) |
| KR (1) | KR101321619B1 (pm) |
| AU (1) | AU2005316421B2 (pm) |
| BE (1) | BE2015C015I2 (pm) |
| BR (1) | BRPI0516408B8 (pm) |
| CA (1) | CA2591534C (pm) |
| DK (1) | DK2213652T3 (pm) |
| EA (1) | EA012334B1 (pm) |
| ES (1) | ES2526655T3 (pm) |
| FR (1) | FR15C0012I2 (pm) |
| HU (1) | HUS1500014I1 (pm) |
| IL (2) | IL183946A (pm) |
| LT (1) | LTC2213652I2 (pm) |
| LU (1) | LU92647I2 (pm) |
| MX (1) | MX2007007380A (pm) |
| NL (1) | NL300719I1 (pm) |
| NO (1) | NO339195B1 (pm) |
| NZ (1) | NZ555942A (pm) |
| PL (1) | PL2213652T3 (pm) |
| PT (1) | PT2213652E (pm) |
| SG (1) | SG194363A1 (pm) |
| SI (1) | SI2213652T1 (pm) |
| WO (1) | WO2006066104A2 (pm) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2456411C (en) * | 2001-08-27 | 2011-02-15 | The Trustees Of The University Of Pennsylvania | Stilbene derivatives and their use for binding and imaging amyloid plaques |
| SI2213652T1 (sl) * | 2004-12-17 | 2015-03-31 | The Trustees Of The University Of Pennsylvania | Derivati stilbena in njihova uporaba za vezavo in prikaz amiloidnih plakov |
| US7858072B2 (en) * | 2004-12-17 | 2010-12-28 | The Trustees Of The University Of Pennsylvania | Stilbene derivatives and their use for binding and imaging amyloid plaques |
| US20070031328A1 (en) * | 2005-06-24 | 2007-02-08 | Kung Hank F | Radiolabeled-pegylation of ligands for use as imaging agents |
| LT2363392T (lt) | 2006-03-30 | 2017-07-25 | The Trustees Of The University Of Pennsylvania | Stirilpiridino dariniai ir jų panaudojimas amiloido plokštelių surišimui ir vizualizavimui |
| US20080253967A1 (en) * | 2007-04-13 | 2008-10-16 | Kung Hank F | Halo-Stilbene Derivatives And Their Use For Binding And Imaging Of Amyloid Plaques |
| WO2009001046A2 (en) * | 2007-06-22 | 2008-12-31 | The University Court Of The University Of Aberdeen | [11c]methoxy-radiolabelled 2,3',4,5'-tetramethylstilbene (tms) and its preparation and use |
| CA2699965A1 (en) * | 2007-07-04 | 2009-01-08 | Tohoku University | Pet probe having an alkoxy group substituted by fluorine and hydroxy group |
| ES2447940T3 (es) * | 2007-10-15 | 2014-03-13 | The Salk Institute For Biological Studies | Métodos para el tratamiento de varias enfermedades y afecciones, y compuestos útiles para los mismos |
| US8932557B2 (en) | 2008-02-14 | 2015-01-13 | Eli Lilly And Company | Imaging agents for detecting neurological dysfunction |
| LT2247558T (lt) * | 2008-02-14 | 2022-04-11 | Eli Lilly And Company | Nauji vizualizavimo agentai neurologinės disfunkcijos aptikimui |
| AU2009219406A1 (en) * | 2008-02-27 | 2009-09-03 | Avid Radiopharmaceuticals, Inc. | Gamma probe detection of amyloid plaque using radiolabeled A-beta binding compounds |
| US8557222B2 (en) | 2008-04-04 | 2013-10-15 | Avid Radiopharmaceuticals, Inc. | Radiopharmaceutical imaging of neurodegenerative diseases |
| US20100145194A1 (en) * | 2008-11-13 | 2010-06-10 | Avid Radiopharmaceuticals, Inc. | Histogram-based analysis method for the detection and diagnosis of neurodegenerative diseases |
| WO2010072342A2 (en) | 2008-12-22 | 2010-07-01 | Bayer Schering Pharma Aktiengesellschaft | A method for the synthesis of a radionuclide-labeled compound |
| UA105914C2 (uk) * | 2008-12-31 | 2014-07-10 | Евід Рейдіофармасьютікалз, Інк. | Синтез стирилпіридину, міченого радіоізотопом 18f, з тозилатного прекурсора та стабільна фармацевтична композиція на його основі |
| CU23844B1 (es) | 2009-04-17 | 2012-10-15 | Ct De Neurociencias De Cuba | Procedimiento de obtención de nuevos derivados de naftaleno para el diagnóstico in vivo de la enfermedad de alzheimer |
| CN102471177A (zh) * | 2009-07-10 | 2012-05-23 | 拜耳医药股份有限公司 | 低至中压液相色谱在放射性示踪剂纯化中的应用 |
| UY33152A (es) * | 2009-12-23 | 2011-07-29 | Bayer Schering Pharma Ag | Formulaciones adecuadas para el diagnostico por imagenes con pet |
| SG185783A1 (en) | 2010-06-04 | 2013-01-30 | Piramal Imaging Sa | Method for production of f-18 labeled amyloid beta ligands |
| TWI504414B (zh) * | 2010-06-04 | 2015-10-21 | Bayer Schering Pharma Ag | 生產Ｆ－１８標記之Ａβ配位體之方法 |
| KR20130088117A (ko) * | 2010-06-04 | 2013-08-07 | 피라말 이미징 에스에이 | Ｆ-18 표지된 아밀로이드 베타 리간드의 제조 방법 |
| ES2642086T5 (es) | 2010-06-04 | 2020-04-13 | Life Molecular Imaging Sa | Procedimiento para la producción de ligandos de beta amiloide marcados con F-18 |
| US9259495B2 (en) * | 2010-10-12 | 2016-02-16 | Mayo Foundation For Medical Education And Research | Imaging of meningiomas using phenylbenzothiazole, stilbene, or biphenylalkyne derivatives |
| CA3058702C (en) * | 2011-04-21 | 2023-11-07 | Massoud Akhtari | Functionalized magnetic nanoparticles and use in imaging amyloid deposits and neurofibrillary tangles |
| EP2723394B1 (en) | 2011-06-21 | 2018-05-23 | Piramal Imaging SA | Formulations of fluorinated stilbene suitable for pet imaging |
| KR101291037B1 (ko) * | 2011-10-12 | 2013-08-01 | 사회복지법인 삼성생명공익재단 | 레스베라트롤 유도체와 스티릴-오각형 방향족 화합물 및 이들의 베타-아밀로이드 플라그에 대한 결합제 및 진단영상제의 용도 |
| RU2477726C1 (ru) * | 2011-10-18 | 2013-03-20 | Общество С Ограниченной Ответственностью "Ньювак" (Ооо "Ньювак") | Замещенные феноксиуксусные кислоты, их эфиры и амиды, включающие 2,6-диоксо-2,3,6,7-тетрагидро-1н-пурин-8-иловый фрагмент, - антагонисты аденозинового a2a рецептора и их применение |
| AU2012324940A1 (en) | 2011-10-19 | 2014-04-17 | Piramal Imaging Sa | Improved method for production of F-18 labeled Abeta ligands |
| KR101930124B1 (ko) | 2012-04-10 | 2018-12-17 | 랜티우스 메디컬 이메징, 인크. | 방사성제약 합성 방법 |
| US9180212B2 (en) * | 2012-05-22 | 2015-11-10 | The Regents Of The University Of California | β-amyloid plaque imaging agents |
| CU20130027A7 (es) | 2013-02-28 | 2014-10-30 | Ct De Neurociencias De Cuba | Chaperoninas químicas como nuevos moduladores moleculares de la beta agregación proteica presente en las enfermedades conformacionales |
| JP6041751B2 (ja) * | 2013-05-07 | 2016-12-14 | 日本メジフィジックス株式会社 | スチリルピリジン誘導体化合物 |
| JP2014218454A (ja) * | 2013-05-07 | 2014-11-20 | 日本メジフィジックス株式会社 | スチリルピリジン誘導体化合物 |
| KR101891404B1 (ko) | 2015-12-18 | 2018-08-24 | 주식회사 엘지화학 | 변성 단량체, 이를 포함하는 변성 중합체 및 이들의 제조방법 |
| CN109790184B (zh) | 2016-09-29 | 2021-06-29 | 韩国原子力研究院 | 姜黄素衍生物、其制备方法、以及用于检测β-淀粉样蛋白斑的包含该姜黄素衍生物的光声成像剂 |
| JOP20190077A1 (ar) | 2016-10-10 | 2019-04-09 | Array Biopharma Inc | مركبات بيرازولو [1، 5-a]بيريدين بها استبدال كمثبطات كيناز ret |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4500507A (en) * | 1981-10-30 | 1985-02-19 | Wong Dennis W | Diagnostic composition for radiologic imaging of neoplasms in the body and method of preparation |
| JPS60247244A (ja) * | 1984-05-22 | 1985-12-06 | Mitsubishi Paper Mills Ltd | 電子写真感光体 |
| DD234666A1 (de) | 1984-11-01 | 1986-04-09 | Univ Leipzig | Verfahren zur herstellung von einfachen und substituierten 4-dimethylamino-alpha-halogenstilbenen |
| DD231432A1 (de) | 1984-11-01 | 1985-12-24 | Univ Leipzig | Material zur silberfreien bildaufzeichnung |
| JPH06329566A (ja) | 1993-05-21 | 1994-11-29 | Asahi Glass Co Ltd | ジフルオロスチルベン誘導体化合物およびそれを含有する液晶組成物 |
| TW325458B (en) * | 1993-09-08 | 1998-01-21 | Ajinomoto Kk | Stilbene derivatives and pharmaceutical compositions comprising the same for anti-cancer |
| US5601801A (en) * | 1994-08-02 | 1997-02-11 | Merck Frosst Canada, Inc. | Radiolabelled angiotensin converting enzyme inhibitors |
| US5521213A (en) * | 1994-08-29 | 1996-05-28 | Merck Frosst Canada, Inc. | Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2 |
| JP4022951B2 (ja) | 1997-08-06 | 2007-12-19 | 大日本インキ化学工業株式会社 | ジフルオロスチルベン誘導体の製造方法 |
| AU5822301A (en) * | 2000-05-08 | 2001-11-20 | Novozymes A/S | Oxidoreductase mediated antimicrobial activity |
| CA2456411C (en) * | 2001-08-27 | 2011-02-15 | The Trustees Of The University Of Pennsylvania | Stilbene derivatives and their use for binding and imaging amyloid plaques |
| KR100789847B1 (ko) * | 2004-12-15 | 2007-12-28 | (주)퓨쳐켐 | 알코올 용매하에서 유기플루오로 화합물의 제조방법 |
| SI2213652T1 (sl) * | 2004-12-17 | 2015-03-31 | The Trustees Of The University Of Pennsylvania | Derivati stilbena in njihova uporaba za vezavo in prikaz amiloidnih plakov |
| US7858072B2 (en) * | 2004-12-17 | 2010-12-28 | The Trustees Of The University Of Pennsylvania | Stilbene derivatives and their use for binding and imaging amyloid plaques |
| US20070031328A1 (en) * | 2005-06-24 | 2007-02-08 | Kung Hank F | Radiolabeled-pegylation of ligands for use as imaging agents |
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2005
- 2005-12-19 SI SI200531929T patent/SI2213652T1/sl unknown
- 2005-12-19 PL PL10161604T patent/PL2213652T3/pl unknown
- 2005-12-19 JP JP2007546948A patent/JP5128956B2/ja active Active
- 2005-12-19 NZ NZ555942A patent/NZ555942A/en unknown
- 2005-12-19 WO PCT/US2005/045682 patent/WO2006066104A2/en active Application Filing
- 2005-12-19 EP EP10161604.3A patent/EP2213652B1/en active Active
- 2005-12-19 PT PT101616043T patent/PT2213652E/pt unknown
- 2005-12-19 EA EA200701299A patent/EA012334B1/ru not_active IP Right Cessation
- 2005-12-19 MX MX2007007380A patent/MX2007007380A/es active IP Right Grant
- 2005-12-19 US US11/305,333 patent/US7807135B2/en active Active
- 2005-12-19 SG SG2013070958A patent/SG194363A1/en unknown
- 2005-12-19 DK DK10161604.3T patent/DK2213652T3/en active
- 2005-12-19 AU AU2005316421A patent/AU2005316421B2/en active Active
- 2005-12-19 BR BRPI0516408A patent/BRPI0516408B8/pt active IP Right Grant
- 2005-12-19 CA CA2591534A patent/CA2591534C/en active Active
- 2005-12-19 EP EP05857100A patent/EP1838298A4/en not_active Withdrawn
- 2005-12-19 KR KR1020077016290A patent/KR101321619B1/ko active Active
- 2005-12-19 EP EP05854410A patent/EP1841465A4/en not_active Withdrawn
- 2005-12-19 ES ES10161604.3T patent/ES2526655T3/es active Active
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2007
- 2007-06-14 IL IL183946A patent/IL183946A/en active IP Right Grant
- 2007-07-16 NO NO20073650A patent/NO339195B1/no unknown
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2010
- 2010-04-22 US US12/765,397 patent/US8465726B2/en active Active
- 2010-05-31 IL IL206091A patent/IL206091A/en active IP Right Grant
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2015
- 2015-02-02 LT LTPA2015005C patent/LTC2213652I2/lt unknown
- 2015-02-04 LU LU92647C patent/LU92647I2/xx unknown
- 2015-02-11 FR FR15C0012C patent/FR15C0012I2/fr active Active
- 2015-02-12 NL NL300719C patent/NL300719I1/nl unknown
- 2015-03-10 BE BE2015C015C patent/BE2015C015I2/nl unknown
- 2015-03-18 HU HUS1500014C patent/HUS1500014I1/hu unknown