DK2836241T3 - Fremgangsmåde til syntese af radioaktivt lægemiddel - Google Patents
Fremgangsmåde til syntese af radioaktivt lægemiddel Download PDFInfo
- Publication number
- DK2836241T3 DK2836241T3 DK13790824.0T DK13790824T DK2836241T3 DK 2836241 T3 DK2836241 T3 DK 2836241T3 DK 13790824 T DK13790824 T DK 13790824T DK 2836241 T3 DK2836241 T3 DK 2836241T3
- Authority
- DK
- Denmark
- Prior art keywords
- synthesis
- medicinal product
- radioactive
- radioactive medicinal
- product
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/121—Solutions, i.e. homogeneous liquid formulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0404—Lipids, e.g. triglycerides; Polycationic carriers
- A61K51/0406—Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0453—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Dispersion Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261622515P | 2012-04-10 | 2012-04-10 | |
| US201361785623P | 2013-03-14 | 2013-03-14 | |
| PCT/US2013/036027 WO2013173004A2 (en) | 2012-04-10 | 2013-04-10 | Radiopharmaceutical synthesis methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2836241T3 true DK2836241T3 (da) | 2019-05-13 |
Family
ID=49584432
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13790824.0T DK2836241T3 (da) | 2012-04-10 | 2013-04-10 | Fremgangsmåde til syntese af radioaktivt lægemiddel |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10568978B2 (da) |
| EP (1) | EP2836241B1 (da) |
| JP (1) | JP6207588B2 (da) |
| KR (1) | KR101930124B1 (da) |
| CN (2) | CN104244991A (da) |
| AU (2) | AU2013263297B2 (da) |
| BR (1) | BR112014024997B1 (da) |
| CA (1) | CA2869398C (da) |
| DK (1) | DK2836241T3 (da) |
| ES (1) | ES2725314T3 (da) |
| PT (1) | PT2836241T (da) |
| SG (2) | SG11201406206RA (da) |
| WO (1) | WO2013173004A2 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2016008466A (es) * | 2016-06-24 | 2017-12-25 | Instituto Nac De Investigaciones Nucleares | 99mtc-edda/hynic-ipsma como un radiofarmaco para la deteccion de la sobre-expresion del antigeno prostatico de membrana. |
| US10695450B2 (en) | 2016-07-26 | 2020-06-30 | Laboratoires Cyclopharma | Synthesis of a radioactive agent composition |
| FR3054445B1 (fr) * | 2016-07-26 | 2019-07-05 | Laboratoires Cyclopharma | Synthese d'une composition d'agent radioactif |
| JPWO2020202831A1 (da) * | 2019-03-29 | 2020-10-08 | ||
| AR125188A1 (es) | 2021-03-22 | 2023-06-21 | Neurocrine Biosciences Inc | Inhibidores del vmat2 y métodos de uso |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7344702B2 (en) | 2004-02-13 | 2008-03-18 | Bristol-Myers Squibb Pharma Company | Contrast agents for myocardial perfusion imaging |
| AU2005316421B2 (en) | 2004-12-17 | 2012-04-05 | The Trustees Of The University Of Pennsylvania | Stilbene derivatives and their use for binding and imaging amyloid plaques |
| PT1999109E (pt) | 2006-03-30 | 2012-03-16 | Univ Pennsylvania | Derivados de estirilpiridina e sua utilização para ligação e obtenção de imagens de placas amilóides |
| PT2114873E (pt) | 2006-12-26 | 2013-05-06 | Lantheus Medical Imaging Inc | Ligandos para imagiologia de inervação cardíaca |
| AU2008292201B2 (en) | 2007-08-30 | 2014-09-04 | Ge Healthcare Limited | Radiopharmaceutical composition |
| CA2967254C (en) | 2008-02-29 | 2019-03-26 | Lantheus Medical Imaging, Inc. | Contrast agents for applications including imaging cancer |
| EP2110367A1 (en) | 2008-04-14 | 2009-10-21 | Bayer Schering Pharma Aktiengesellschaft | Purification strategy for direct nucleophilic procedures |
| GB0819293D0 (en) * | 2008-10-21 | 2008-11-26 | Hammersmith Imanet Ltd | Radiofluorination |
| EP2419096B1 (en) * | 2009-04-15 | 2019-11-13 | Lantheus Medical Imaging, Inc. | Stabilization of radiopharmaceutical compositions using ascorbic acid |
| EP2454216A1 (en) | 2009-07-11 | 2012-05-23 | Bayer Pharma Aktiengesellschaft | Non-polar and polar leaving groups |
| CN102762229B9 (zh) * | 2009-12-23 | 2020-12-01 | 皮拉马影像股份公司 | 适用于用疏水pet试剂pet成像的配方 |
| SG10201500929XA (en) | 2010-02-08 | 2015-04-29 | Lantheus Medical Imaging Inc | Methods and apparatus for synthesizing imaging agents, and intermediates thereof |
| KR102008635B1 (ko) | 2010-05-11 | 2019-08-07 | 랜티우스 메디컬 이메징, 인크. | 영상화제의 합성 및 사용을 위한 조성물, 방법 및 시스템 |
| WO2012021882A2 (en) | 2010-08-13 | 2012-02-16 | Siemens Medical Solutions Usa, Inc. | Formulation, apparatus and method for stabilizing radiopharmaceuticals |
| JP2013542187A (ja) | 2010-09-21 | 2013-11-21 | ジーイー・ヘルスケア・リミテッド | 新規放射性トレーサー |
| JP6081997B2 (ja) | 2011-06-21 | 2017-02-15 | ピラマル イメージング ソシエテ アノニム | Ｐｅｔイメージングに適したフッ素化スチルベンの製剤 |
| EP2753605B1 (en) | 2011-09-09 | 2019-03-27 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
| AU2013203000B9 (en) | 2012-08-10 | 2017-02-02 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
-
2013
- 2013-04-10 CA CA2869398A patent/CA2869398C/en active Active
- 2013-04-10 SG SG11201406206RA patent/SG11201406206RA/en unknown
- 2013-04-10 JP JP2015505884A patent/JP6207588B2/ja active Active
- 2013-04-10 EP EP13790824.0A patent/EP2836241B1/en active Active
- 2013-04-10 ES ES13790824T patent/ES2725314T3/es active Active
- 2013-04-10 US US14/390,425 patent/US10568978B2/en active Active
- 2013-04-10 DK DK13790824.0T patent/DK2836241T3/da active
- 2013-04-10 CN CN201380019259.4A patent/CN104244991A/zh active Pending
- 2013-04-10 PT PT13790824T patent/PT2836241T/pt unknown
- 2013-04-10 SG SG10201608370TA patent/SG10201608370TA/en unknown
- 2013-04-10 KR KR1020147031107A patent/KR101930124B1/ko active IP Right Grant
- 2013-04-10 AU AU2013263297A patent/AU2013263297B2/en active Active
- 2013-04-10 CN CN201811050819.3A patent/CN109125745B/zh active Active
- 2013-04-10 WO PCT/US2013/036027 patent/WO2013173004A2/en active Application Filing
- 2013-04-10 BR BR112014024997-0A patent/BR112014024997B1/pt active IP Right Grant
-
2018
- 2018-02-27 AU AU2018201405A patent/AU2018201405B2/en active Active
-
2020
- 2020-01-17 US US16/745,446 patent/US20200324002A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2869398A1 (en) | 2013-11-21 |
| WO2013173004A2 (en) | 2013-11-21 |
| SG10201608370TA (en) | 2016-11-29 |
| EP2836241A2 (en) | 2015-02-18 |
| WO2013173004A8 (en) | 2014-01-23 |
| US20200324002A1 (en) | 2020-10-15 |
| ES2725314T3 (es) | 2019-09-23 |
| CN109125745A (zh) | 2019-01-04 |
| JP6207588B2 (ja) | 2017-10-04 |
| WO2013173004A3 (en) | 2014-03-13 |
| CN109125745B (zh) | 2022-07-26 |
| JP2015514133A (ja) | 2015-05-18 |
| AU2018201405A1 (en) | 2018-03-15 |
| KR20140144731A (ko) | 2014-12-19 |
| EP2836241A4 (en) | 2015-11-11 |
| KR101930124B1 (ko) | 2018-12-17 |
| AU2013263297A1 (en) | 2014-10-23 |
| AU2018201405B2 (en) | 2019-05-02 |
| PT2836241T (pt) | 2019-05-30 |
| CN104244991A (zh) | 2014-12-24 |
| US10568978B2 (en) | 2020-02-25 |
| US20150056136A1 (en) | 2015-02-26 |
| CA2869398C (en) | 2019-10-22 |
| AU2013263297B2 (en) | 2017-11-30 |
| BR112014024997B1 (pt) | 2021-03-09 |
| SG11201406206RA (en) | 2014-10-30 |
| EP2836241B1 (en) | 2019-02-20 |
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