|
GB0018891D0
(en)
*
|
2000-08-01 |
2000-09-20 |
Novartis Ag |
Organic compounds
|
|
WO2003057214A1
(en)
|
2001-12-28 |
2003-07-17 |
Somatocor Pharmaceuticals, Inc. |
Imidazolidin-2,4-dione derivatives as non-peptide somatostatin receptor ligands
|
|
WO2004052817A1
(en)
*
|
2002-12-12 |
2004-06-24 |
Novartis Ag |
Process for peptide synthesis of peptides containing a 4-hydroxy-proline substructure
|
|
GB0229020D0
(en)
*
|
2002-12-12 |
2003-01-15 |
Novartis Ag |
Organic compounds
|
|
GB0300095D0
(en)
*
|
2003-01-03 |
2003-02-05 |
Novartis Ag |
Organic compounds
|
|
GB0314695D0
(en)
*
|
2003-06-24 |
2003-07-30 |
Novartis Ag |
Organic compounds
|
|
AR044852A1
(es)
*
|
2003-06-24 |
2005-10-05 |
Novartis Ag |
Una composicion farmaceutica para la administracion parenteral que comprende un analogo de somatostatina
|
|
GB0318682D0
(en)
*
|
2003-08-08 |
2003-09-10 |
Novartis Ag |
Organic compounds
|
|
EP1522311A1
(fr)
|
2003-10-10 |
2005-04-13 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Utilisation de la somatostine ou d'un de ses analogues pour préparer un médicament destiné à réguler la réserve folliculaire ovarienne chez la femme non ménopausée
|
|
MY158342A
(en)
*
|
2003-11-14 |
2016-09-30 |
Novartis Ag |
Pharmaceutical composition
|
|
GB0412866D0
(en)
*
|
2004-06-09 |
2004-07-14 |
Novartis Ag |
Organic compounds
|
|
GB0428151D0
(en)
*
|
2004-12-22 |
2005-01-26 |
Novartis Ag |
Organic compounds
|
|
GB0602639D0
(en)
|
2006-02-09 |
2006-03-22 |
Novartis Ag |
Organic compounds
|
|
RU2008151727A
(ru)
*
|
2006-06-08 |
2010-07-20 |
Новартис АГ (CH) |
Комбинация аналогов соматостатина с антагонистом рецептора дофамина или рецептора гормона роста
|
|
US7697338B2
(en)
*
|
2006-11-16 |
2010-04-13 |
Sandisk Corporation |
Systems for controlled boosting in non-volatile memory soft programming
|
|
WO2008064570A1
(en)
*
|
2006-11-28 |
2008-06-05 |
The University Of Hong Kong |
The use of granulin-epithelin precursor (gep) antibodies for detection and suppression of hepatocellular carcinoma (hcc)
|
|
EP1941902A1
(en)
*
|
2007-01-02 |
2008-07-09 |
Novartis AG |
Use of Somatostatin analogs in cluster headache
|
|
JP5649825B2
(ja)
|
2007-01-31 |
2015-01-07 |
デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド |
安定化させたp53ペプチドおよびその使用法
|
|
KR101623985B1
(ko)
|
2007-03-28 |
2016-05-25 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
스티칭된 폴리펩티드
|
|
AR066677A1
(es)
|
2007-05-24 |
2009-09-02 |
Novartis Ag |
Formulacion de pasireotida. composicion farmaceutica para liberacion prolongada. microparticulas.
|
|
WO2009009035A1
(en)
*
|
2007-07-06 |
2009-01-15 |
Ipsen Pharma S.A.S. |
Somatostatin analog and uses thereof
|
|
GB0719818D0
(en)
*
|
2007-10-11 |
2007-11-21 |
Asterion Ltd |
Growth hormone fusion polypeptides
|
|
US20100273719A1
(en)
*
|
2007-11-28 |
2010-10-28 |
Novartis Ag |
Use of somatostatin analogs in meningioma
|
|
EP2067786A1
(en)
|
2007-12-07 |
2009-06-10 |
ITALFARMACO S.p.A. |
Novel non selective analogs of somatostatin
|
|
EP2225271B1
(en)
|
2007-12-03 |
2013-07-31 |
ITALFARMACO S.p.A. |
New non-selective somatostatin analogues
|
|
US20090325863A1
(en)
*
|
2008-06-13 |
2009-12-31 |
Kleinberg David L |
Somatostatin analogs and IGF-I inhibition for breast cancer prevention
|
|
JP5721624B2
(ja)
|
2008-07-08 |
2015-05-20 |
ノバルティス アーゲー |
内因性高インスリン血症性低血糖症の治療のためのパシレオチドの使用
|
|
EP2172189A1
(en)
|
2008-10-01 |
2010-04-07 |
Novartis AG |
Pharmaceutical Compositions
|
|
EP2213307A1
(en)
|
2009-02-03 |
2010-08-04 |
Novartis AG |
Injectable depot formulations
|
|
CN106974888B
(zh)
|
2008-09-17 |
2019-08-02 |
克艾思马有限公司 |
药物组合物和相关的给药方法
|
|
UY33236A
(es)
|
2010-02-25 |
2011-09-30 |
Novartis Ag |
Inhibidores dimericos de las iap
|
|
WO2012021874A1
(en)
|
2010-08-13 |
2012-02-16 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles with thioether linkers
|
|
US8629103B2
(en)
|
2010-12-02 |
2014-01-14 |
New York University |
Treatment of non-proliferative cystic disease of the breast
|
|
JP2014501235A
(ja)
|
2010-12-13 |
2014-01-20 |
ノバルティス アーゲー |
二量体iap阻害剤
|
|
UY33794A
(es)
|
2010-12-13 |
2012-07-31 |
Novartis Ag |
Inhibidores diméricos de las iap
|
|
US20130035054A1
(en)
*
|
2011-07-14 |
2013-02-07 |
Faceon Mobile |
Phone with multi-portal access for display during incoming and outgoing call
|
|
WO2013019923A2
(en)
|
2011-08-02 |
2013-02-07 |
New York University |
Methods for detecting progenitor cells and uses thereof
|
|
SG11201400989TA
(en)
|
2011-09-27 |
2014-04-28 |
Novartis Ag |
3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant idh
|
|
US9096684B2
(en)
|
2011-10-18 |
2015-08-04 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles
|
|
EP2787974B1
(en)
|
2011-12-05 |
2017-05-24 |
Camurus Ab |
Robust controlled-release peptide formulations
|
|
BR112014013411A2
(pt)
|
2011-12-05 |
2017-06-13 |
Novartis Ag |
derivados de ureia cíclica como antagonistas de receptores androgênicos
|
|
US10023862B2
(en)
|
2012-01-09 |
2018-07-17 |
Arrowhead Pharmaceuticals, Inc. |
Organic compositions to treat beta-catenin-related diseases
|
|
US8815926B2
(en)
|
2012-01-26 |
2014-08-26 |
Novartis Ag |
Substituted pyrrolo[3,4-D]imidazoles for the treatment of MDM2/4 mediated diseases
|
|
CN104159595A
(zh)
|
2012-02-15 |
2014-11-19 |
爱勒让治疗公司 |
拟肽大环化合物
|
|
CA2864120A1
(en)
|
2012-02-15 |
2013-08-22 |
Aileron Therapeutics, Inc. |
Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
|
|
BR112014029425A2
(pt)
*
|
2012-05-25 |
2017-06-27 |
Camurus Ab |
pré-formulação, dispositivo de administração pré-cheio, kit, processo para a formação de uma pré-formulação, usos de mistura e de um solvente polar, e, método para o tratamento de um sujeito
|
|
TWI704919B
(zh)
|
2012-05-31 |
2020-09-21 |
日商大塚製藥股份有限公司 |
用於預防及/或治療多囊性腎臟病之藥物
|
|
MX2015005244A
(es)
|
2012-11-01 |
2015-07-14 |
Aileron Therapeutics Inc |
Aminoacidos disustituidos y metodos de preparacion y el uso de los mismos.
|
|
US9480759B2
(en)
|
2012-11-21 |
2016-11-01 |
Serene, Llc |
Tin-117m somatostatin receptor binding compounds and methods
|
|
LT2958907T
(lt)
|
2013-02-19 |
2018-04-25 |
Novartis Ag |
Benzotiofeno dariniai ir jų kompozicijos, kaip selektyvūs estrogeno receptorių degradavimo agentai
|
|
KR20150131224A
(ko)
|
2013-03-14 |
2015-11-24 |
노파르티스 아게 |
돌연변이 idh의 억제제로서의 3-피리미딘-4-일-옥사졸리딘-2-온
|
|
BR112015022483A2
(pt)
|
2013-03-14 |
2017-07-18 |
Novartis Ag |
3-pirimidin-4-il-oxazolidin-2-onas como inibidores de idh mutante
|
|
WO2014147586A1
(en)
|
2013-03-22 |
2014-09-25 |
Novartis Ag |
1-(2-(ethylamino)pyrimidin-4-yl)pyrrolidin-2-ones as inhibitors of mutant idh
|
|
CN103467575B
(zh)
*
|
2013-08-22 |
2016-03-02 |
深圳翰宇药业股份有限公司 |
一种帕西瑞肽的制备方法
|
|
CN103641894B
(zh)
*
|
2013-12-06 |
2015-10-28 |
深圳翰宇药业股份有限公司 |
一种治疗库欣病的多肽药物的制备方法
|
|
WO2015092634A1
(en)
|
2013-12-16 |
2015-06-25 |
Novartis Ag |
1,2,3,4-tetrahydroisoquinoline compounds and compositions as selective estrogen receptor antagonists and degraders
|
|
EP3082765B1
(en)
|
2013-12-19 |
2018-08-01 |
Novartis AG |
Drug delivery systems
|
|
CN105899493B
(zh)
|
2014-01-17 |
2019-03-29 |
诺华股份有限公司 |
用于抑制shp2活性的1-(三嗪-3-基/哒嗪-3-基)-哌(-嗪)啶衍生物及其组合物
|
|
CN105899491B
(zh)
|
2014-01-17 |
2019-04-02 |
诺华股份有限公司 |
用于抑制shp2活性的1-哒嗪-/三嗪-3-基-哌(-嗪)/啶/吡咯烷衍生物及其组合物
|
|
JO3517B1
(ar)
|
2014-01-17 |
2020-07-05 |
Novartis Ag |
ان-ازاسبيرو الكان حلقي كبديل مركبات اريل-ان مغايرة وتركيبات لتثبيط نشاط shp2
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
HRP20192346T1
(hr)
|
2014-03-14 |
2020-03-20 |
Novartis Ag |
Molekule anti-lag-3 antitijela i njihove uporabe
|
|
JP2017516779A
(ja)
|
2014-05-28 |
2017-06-22 |
アイデニクス・ファーマシューティカルズ・エルエルシー |
癌治療のためのヌクレオシド誘導体
|
|
MX2017003797A
(es)
|
2014-09-24 |
2017-06-15 |
Aileron Therapeutics Inc |
Macrociclos peptidomimeticos y usos de los mismos.
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
CN114920840A
(zh)
|
2014-10-14 |
2022-08-19 |
诺华股份有限公司 |
针对pd-l1的抗体分子及其用途
|
|
WO2016089797A1
(en)
|
2014-12-05 |
2016-06-09 |
Merck Sharp & Dohme Corp. |
Novel tricyclic compounds as inhibitors of mutant idh enzymes
|
|
EP3226689B1
(en)
|
2014-12-05 |
2020-01-15 |
Merck Sharp & Dohme Corp. |
Novel tricyclic compounds as inhibitors of mutant idh enzymes
|
|
EP3226690B1
(en)
|
2014-12-05 |
2020-05-20 |
Merck Sharp & Dohme Corp. |
Novel tricyclic compounds as inhibitors of mutant idh enzymes
|
|
AU2015360485B2
(en)
|
2014-12-10 |
2020-06-25 |
Amryt Endo, Inc. |
Oral octreotide administered in combination with other therapeutic agents
|
|
US20170340733A1
(en)
|
2014-12-19 |
2017-11-30 |
Novartis Ag |
Combination therapies
|
|
US20210317161A1
(en)
|
2014-12-19 |
2021-10-14 |
Auro Peptides Ltd |
A process for the preparation of pasireotide
|
|
FI3253401T3
(fi)
|
2015-02-03 |
2025-07-09 |
Amryt Endo Inc |
Akromegallian hoitaminen suun kautta annettavalla oktreotidilla
|
|
MY190404A
(en)
|
2015-03-10 |
2022-04-21 |
Aduro Biotech Inc |
Compositions and methods for activating "stimulator of interferon gene"-dependent signalling
|
|
EP3294318A4
(en)
|
2015-03-20 |
2019-04-03 |
Aileron Therapeutics, Inc. |
PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF
|
|
EP3280723B1
(en)
*
|
2015-04-08 |
2021-01-06 |
Polyphor AG |
Backbone-cyclized peptidomimetics
|
|
HK1252245A1
(zh)
|
2015-05-27 |
2019-05-24 |
Idenix Pharmaceuticals Llc |
用於治疗癌症的核苷酸
|
|
ES2741746T3
(es)
|
2015-06-19 |
2020-02-12 |
Novartis Ag |
Compuestos y composiciones para inhibir la actividad de SHP2
|
|
CN107787323B
(zh)
|
2015-06-19 |
2020-09-01 |
诺华股份有限公司 |
用于抑制shp2活性的化合物和组合物
|
|
JP6718889B2
(ja)
|
2015-06-19 |
2020-07-08 |
ノバルティス アーゲー |
Shp2の活性を阻害するための化合物および組成物
|
|
US10556924B2
(en)
|
2015-06-22 |
2020-02-11 |
Biophore India Pharmaceuticals Pvt. Ltd. |
Process for the preparation of pasireotide
|
|
GB201511790D0
(en)
|
2015-07-06 |
2015-08-19 |
Iomet Pharma Ltd |
Pharmaceutical compound
|
|
HUE055469T2
(hu)
|
2015-07-29 |
2021-11-29 |
Novartis Ag |
A LAG-3 elleni antitest molekulákat tartalmazó kombinált terápiák
|
|
US20180222982A1
(en)
|
2015-07-29 |
2018-08-09 |
Novartis Ag |
Combination therapies comprising antibody molecules to pd-1
|
|
EP3316902A1
(en)
|
2015-07-29 |
2018-05-09 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
|
US11453697B1
(en)
|
2015-08-13 |
2022-09-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
|
CR20180101A
(es)
|
2015-08-13 |
2018-04-12 |
Merck Sharp & Dohme |
Compuestos di-nucleóticos cíclicos como agonistas de sting
|
|
AU2016348391A1
(en)
|
2015-11-03 |
2018-05-17 |
Janssen Biotech, Inc. |
Antibodies specifically binding TIM-3 and their uses
|
|
US10538497B2
(en)
|
2015-12-15 |
2020-01-21 |
Merck Sharp & Dohme Corp. |
Compounds as indoleamine 2,3-dioxygenase inhibitors
|
|
JP2019503349A
(ja)
|
2015-12-17 |
2019-02-07 |
ノバルティス アーゲー |
Pd−1に対する抗体分子およびその使用
|
|
DK3452465T3
(da)
|
2016-05-04 |
2021-02-08 |
Genoscience Pharma |
Substituerede 2,4-diaminoquinolinderivater til anvendelse til behandling af proliferative sygdomme
|
|
MX383856B
(es)
|
2016-06-14 |
2025-03-14 |
Novartis Ag |
Compuestos y composiciones para inhibir la actividad de shp2.
|
|
WO2018009466A1
(en)
|
2016-07-05 |
2018-01-11 |
Aduro Biotech, Inc. |
Locked nucleic acid cyclic dinucleotide compounds and uses thereof
|
|
KR102312721B1
(ko)
|
2016-10-04 |
2021-10-13 |
머크 샤프 앤드 돔 코포레이션 |
STING 효능제로서의 벤조[b]티오펜 화합물
|
|
WO2018091542A1
(en)
|
2016-11-21 |
2018-05-24 |
Idenix Pharmaceuticals Llc |
Cyclic phosphate substituted nucleoside derivatives for the treatment of liver diseases
|
|
CN110234404A
(zh)
|
2017-01-27 |
2019-09-13 |
詹森生物科技公司 |
作为sting激动剂的环状二核苷酸
|
|
AU2018212788A1
(en)
|
2017-01-27 |
2019-07-25 |
Janssen Biotech, Inc. |
Cyclic dinucleotides as STING agonists
|
|
UY37695A
(es)
|
2017-04-28 |
2018-11-30 |
Novartis Ag |
Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
|
|
US11466047B2
(en)
|
2017-05-12 |
2022-10-11 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
|
WO2018237173A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
MA49772A
(fr)
|
2017-08-04 |
2021-04-21 |
Merck Sharp & Dohme |
Agonistes benzo[b]thiophène de sting pour le traitement du cancer
|
|
US11312772B2
(en)
|
2017-08-04 |
2022-04-26 |
Merck Sharp & Dohme Corp. |
Combinations of PD-1 antagonists and benzo [b] thiophene STING agonists for cancer treatment
|
|
CA3074304A1
(en)
|
2017-09-11 |
2019-03-14 |
Krouzon Pharmaceuticals, Inc. |
Octahydrocyclopenta[c]pyrrole allosteric inhibitors of shp2
|
|
WO2019067332A1
(en)
|
2017-09-27 |
2019-04-04 |
Merck Sharp & Dohme Corp. |
COMPOSITIONS AND METHODS FOR TREATING CANCER THROUGH A COMBINATION OF PROGRAMMED DEATH ANTIBODY ANTIBODIES (PD-1) AND A CXCR2 ANTAGONIST
|
|
US11180497B2
(en)
*
|
2017-10-18 |
2021-11-23 |
Angex Pharmaceutical, Inc. |
Cyclic compounds as immunomodulating agents
|
|
EP3703692B1
(en)
|
2017-11-01 |
2025-07-23 |
Merck Sharp & Dohme LLC |
Novel substituted tetrahydroquinolin compounds as indoleamine 2,3-dioxygenase (ido) inhibitors
|
|
CN111344287B
(zh)
|
2017-11-14 |
2023-12-19 |
默沙东有限责任公司 |
作为吲哚胺2,3-双加氧酶(ido)抑制剂的新型取代的联芳基化合物
|
|
WO2019099294A1
(en)
|
2017-11-14 |
2019-05-23 |
Merck Sharp & Dohme Corp. |
Novel substituted biaryl compounds as indoleamine 2,3-dioxygenase (ido) inhibitors
|
|
US20210009630A1
(en)
|
2017-12-15 |
2021-01-14 |
Janssen Biotech, Inc. |
Cyclic dinucleotides as sting agonists
|
|
EP3727401A4
(en)
|
2017-12-20 |
2022-04-06 |
Merck Sharp & Dohme Corp. |
CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS
|
|
US12398209B2
(en)
|
2018-01-22 |
2025-08-26 |
Janssen Biotech, Inc. |
Methods of treating cancers with antagonistic anti-PD-1 antibodies
|
|
US12215116B2
(en)
|
2018-03-13 |
2025-02-04 |
Merck Sharp & Dohme Llc |
Arginase inhibitors and methods of use
|
|
WO2019195063A1
(en)
|
2018-04-03 |
2019-10-10 |
Merck Sharp & Dohme Corp. |
Aza-benzothiophene compounds as sting agonists
|
|
MX2020010407A
(es)
|
2018-04-03 |
2020-10-22 |
Merck Sharp & Dohme |
Benzotiofenos y compuestos relacionados como agonistas de sting.
|
|
EP3781687A4
(en)
|
2018-04-20 |
2022-02-09 |
Merck Sharp & Dohme Corp. |
NEW RIG-I SUBSTITUTED AGONISTS: COMPOSITIONS AND METHODS THEREOF
|
|
TWI869346B
(zh)
|
2018-05-30 |
2025-01-11 |
瑞士商諾華公司 |
Entpd2抗體、組合療法、及使用該等抗體和組合療法之方法
|
|
WO2019231870A1
(en)
|
2018-05-31 |
2019-12-05 |
Merck Sharp & Dohme Corp. |
Novel substituted [1.1.1] bicyclo compounds as indoleamine 2,3-dioxygenase inhibitors
|
|
WO2019245890A1
(en)
|
2018-06-20 |
2019-12-26 |
Merck Sharp & Dohme Corp. |
Arginase inhibitors and methods of use
|
|
US10596276B2
(en)
|
2018-07-25 |
2020-03-24 |
Advanced Accelerator Applications (Italy) S.R.L. |
Stable, concentrated radionuclide complex solutions
|
|
TW202517302A
(zh)
|
2018-07-25 |
2025-05-01 |
法商高級催化劑應用品有限公司 |
穩定的、濃縮的放射性核種錯合物溶液
|
|
US10596278B2
(en)
|
2018-07-25 |
2020-03-24 |
Advanced Accelerator Applications (Italy) S.R.L. |
Stable, concentrated radionuclide complex solutions
|
|
CR20210175A
(es)
|
2018-09-18 |
2021-06-01 |
Nikang Therapeutics Inc |
Derivados de anillo tricíclico condensado como inhibidores de la fosfatasa de homología a src 2 (shp2)
|
|
EP3856349A1
(en)
|
2018-09-25 |
2021-08-04 |
Black Diamond Therapeutics, Inc. |
Tyrosine kinase inhibitor compositions, methods of making and methods of use
|
|
BR112021005513A2
(pt)
|
2018-09-25 |
2021-06-22 |
Black Diamond Therapeutics, Inc. |
derivados de quinazolina como inibidor de tirosina quinase, composições, métodos de fabricação e uso dos mesmos
|
|
JP2022502385A
(ja)
|
2018-09-29 |
2022-01-11 |
ノバルティス アーゲー |
Shp2の活性を阻害するための化合物の製造方法
|
|
US12091405B2
(en)
|
2018-11-01 |
2024-09-17 |
Merck Sharp & Dohme Llc |
Substituted pyrazole compounds as indoleamine 2,3-dioxygenase inhibitors
|
|
WO2020096871A1
(en)
|
2018-11-06 |
2020-05-14 |
Merck Sharp & Dohme Corp. |
Novel substituted tricyclic compounds as indoleamine 2,3-dioxygenase inhibitors
|
|
WO2020112581A1
(en)
|
2018-11-28 |
2020-06-04 |
Merck Sharp & Dohme Corp. |
Novel substituted piperazine amide compounds as indoleamine 2, 3-dioxygenase (ido) inhibitors
|
|
US12240867B2
(en)
|
2018-12-18 |
2025-03-04 |
Merck Sharp & Dohme Llc |
Arginase inhibitors and methods of use
|
|
WO2020205688A1
(en)
|
2019-04-04 |
2020-10-08 |
Merck Sharp & Dohme Corp. |
Inhibitors of histone deacetylase-3 useful for the treatment of cancer, inflammation, neurodegeneration diseases and diabetes
|
|
WO2020260547A1
(en)
|
2019-06-27 |
2020-12-30 |
Rigontec Gmbh |
Design method for optimized rig-i ligands
|
|
MX2022001407A
(es)
|
2019-08-02 |
2022-04-27 |
Mersana Therapeutics Inc |
Compuestos derivados y relacionados de bis-[n-((5-carbamoil)-1h be nzo[d]imidazol-2-yl)-pyrazol-5-carboxamida] como agonistas de sting (estimulador de genes de interferón) para el tratamiento de cáncer.
|
|
EP4013749A1
(en)
|
2019-08-15 |
2022-06-22 |
Black Diamond Therapeutics, Inc. |
Alkynyl quinazoline compounds
|
|
JP2022548881A
(ja)
|
2019-09-18 |
2022-11-22 |
ノバルティス アーゲー |
Entpd2抗体、組合せ療法並びに抗体及び組合せ療法を使用する方法
|
|
KR20220100607A
(ko)
|
2019-10-28 |
2022-07-15 |
상하이 인스티튜트 오브 마테리아 메디카 차이니즈 아카데미 오브 싸이언시즈 |
5원 헤테로사이클릭 옥소카르복실산 화합물 및 이의 의약 용도
|
|
US20230074558A1
(en)
|
2019-12-06 |
2023-03-09 |
Mersana Therapeutics, Inc. |
Dimeric compounds as sting agonists
|
|
US20220396577A1
(en)
|
2019-12-17 |
2022-12-15 |
Merck Sharp & Dohme Llc |
Novel substituted 1,3-8-triazaspiro[4,5] decane-2,4-dione compounds as indoleamine 2,3-dioxygenase (ido) and/or tryptophan 2,3-dioxygenase (tdo) inhibitors
|
|
EP4087583A4
(en)
|
2020-01-07 |
2024-01-24 |
Merck Sharp & Dohme LLC |
Arginase inhibitors and methods of use
|
|
WO2021195206A1
(en)
|
2020-03-24 |
2021-09-30 |
Black Diamond Therapeutics, Inc. |
Polymorphic forms and related uses
|
|
EP4218826A3
(en)
|
2020-04-02 |
2023-10-25 |
Mersana Therapeutics, Inc. |
Antibody drug conjugates comprising sting agonists
|
|
PE20230680A1
(es)
|
2020-05-06 |
2023-04-21 |
Merck Sharp And Dohme Llc |
Inhibidores de il4i1 y metodos de uso
|
|
US20250018049A1
(en)
|
2020-12-22 |
2025-01-16 |
Nikang Therapeutics, Inc. |
Compounds for degrading cyclin-dependent kinase 2 via ubiquitin proteosome pathway
|
|
US11141457B1
(en)
|
2020-12-28 |
2021-10-12 |
Amryt Endo, Inc. |
Oral octreotide therapy and contraceptive methods
|
|
JP2024504932A
(ja)
|
2021-01-13 |
2024-02-02 |
モンテ ローザ セラピューティクス, インコーポレイテッド |
イソインドリノン化合物
|
|
WO2022170052A1
(en)
|
2021-02-05 |
2022-08-11 |
Black Diamond Therapeutics, Inc. |
Quinazoline derivatives, pyridopyrimidine derivatives, pyrimidopyrimidine derivatives, and uses thereof
|
|
EP4323350A1
(en)
|
2021-04-14 |
2024-02-21 |
Monte Rosa Therapeutics AG |
Isoindolinone compounds
|
|
WO2022219412A1
(en)
|
2021-04-14 |
2022-10-20 |
Monte Rosa Therapeutics Ag |
Isoindolinone amide compounds useful to treat diseases associated with gspt1
|
|
WO2022227015A1
(en)
|
2021-04-30 |
2022-11-03 |
Merck Sharp & Dohme Corp. |
Il4i1 inhibitors and methods of use
|
|
TW202317589A
(zh)
|
2021-07-14 |
2023-05-01 |
美商尼坎醫療公司 |
作為kras抑制劑的伸烷基衍生物
|
|
EP4499634A1
(en)
|
2022-03-28 |
2025-02-05 |
Nikang Therapeutics, Inc. |
Sulfonamido derivatives as cyclin-dependent kinase 2 inhibitors
|
|
CN119790053A
(zh)
|
2022-06-08 |
2025-04-08 |
霖康疗法公司 |
作为细胞周期蛋白依赖性激酶2抑制剂的磺酰胺衍生物
|
|
WO2024047112A1
(en)
*
|
2022-08-30 |
2024-03-07 |
Somtheranostics Sarl |
Halogenated somatostatin analogs with multiple somatostatin receptor subtype selectivity
|
|
KR20250103630A
(ko)
|
2022-11-11 |
2025-07-07 |
니캉 테라퓨틱스 인코포레이티드 |
유비퀴틴 프로테아좀 경로를 통해 사이클린-의존성 키나제 2를 분해하기 위한 2,5-치환된 피리미딘 유도체를 함유하는 이작용성 화합물
|
|
AR132248A1
(es)
|
2023-03-29 |
2025-06-11 |
Merck Sharp & Dohme Llc |
Inhibidores de il4i1 y métodos para su uso
|
|
WO2025002263A1
(zh)
|
2023-06-30 |
2025-01-02 |
默沙东有限责任公司 |
治疗组合及其用途和治疗方法
|
|
WO2025072462A1
(en)
|
2023-09-27 |
2025-04-03 |
Nikang Therapeutics, Inc. |
Sulfonamide derivatives as cyclin-dependent kinase 2 inhibitors
|
|
WO2025117616A1
(en)
|
2023-11-27 |
2025-06-05 |
Nikang Therapeutics, Inc. |
Bifunctional compounds containing 2,5-substituted pyrimidine derivatives for degrading cyclin-dependent kinase 2 and cyclin-dependent kinase 4 via ubiquitin proteasome pathway
|
|
WO2025117981A1
(en)
|
2023-12-02 |
2025-06-05 |
Nikang Therapeutics, Inc. |
Bifunctional compounds containing 2,5-substituted pyrimidine derivatives for degrading cyclin-dependent kinase 2 via ubiquitin proteasome pathway
|
|
WO2025212828A1
(en)
|
2024-04-03 |
2025-10-09 |
Nikang Therapeutics, Inc. |
Bifunctional compounds containing 2,5-substituted pyrimidine derivatives for degrading cyclin-dependent kinase 2 and cyclin-dependent kinase 4 via ubiquitin proteasome pathway
|
|
WO2025240536A1
(en)
|
2024-05-15 |
2025-11-20 |
Nikang Therapeutics, Inc. |
Bifunctional compounds containing 2,5-substituted pyrimidine derivatives for degrading cyclin-dependent kinase 2 and/or cyclin-dependent kinase 4 via ubiquitin proteasome pathway
|