BE1006834A3 - Solution de perfusion, de conservation et de reperfusion d'organes. - Google Patents

Solution de perfusion, de conservation et de reperfusion d'organes. Download PDF

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Publication number
BE1006834A3
BE1006834A3 BE9101067A BE9101067A BE1006834A3 BE 1006834 A3 BE1006834 A3 BE 1006834A3 BE 9101067 A BE9101067 A BE 9101067A BE 9101067 A BE9101067 A BE 9101067A BE 1006834 A3 BE1006834 A3 BE 1006834A3
Authority
BE
Belgium
Prior art keywords
sep
solution
reperfusion
solutions
solutions according
Prior art date
Application number
BE9101067A
Other languages
English (en)
French (fr)
Inventor
Philippe Menasche
Original Assignee
Pasteur Merieux Serums Vacc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9014424A external-priority patent/FR2669189B1/fr
Priority claimed from FR9109027A external-priority patent/FR2679107B1/fr
Application filed by Pasteur Merieux Serums Vacc filed Critical Pasteur Merieux Serums Vacc
Application granted granted Critical
Publication of BE1006834A3 publication Critical patent/BE1006834A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A61K31/175—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A61K38/063—Glutathione

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
BE9101067A 1990-11-20 1991-11-19 Solution de perfusion, de conservation et de reperfusion d'organes. BE1006834A3 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9014424A FR2669189B1 (fr) 1990-11-20 1990-11-20 Solutions de perfusion et de stockage pour transplantations cardiaques.
FR9109027A FR2679107B1 (fr) 1991-07-17 1991-07-17 Solutions de perfusion, de conservation et de reperfusion d'organes.

Publications (1)

Publication Number Publication Date
BE1006834A3 true BE1006834A3 (fr) 1995-01-03

Family

ID=26228338

Family Applications (1)

Application Number Title Priority Date Filing Date
BE9101067A BE1006834A3 (fr) 1990-11-20 1991-11-19 Solution de perfusion, de conservation et de reperfusion d'organes.

Country Status (8)

Country Link
AT (1) AT399440B (it)
BE (1) BE1006834A3 (it)
CA (1) CA2055827C (it)
CH (1) CH683485A5 (it)
DE (1) DE4138040A1 (it)
ES (1) ES2050580B1 (it)
GB (1) GB2249937B (it)
IT (1) IT1251995B (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1007500A3 (fr) * 1992-09-18 1995-07-18 Pasteur Merieux Serums Vacc Solution de perfusion, de conservation et de reperfusion d'organes.
ATE197530T1 (de) * 1993-05-07 2000-12-15 Chugai Pharmaceutical Co Ltd Organkonservierungsmittel
DE4325547C2 (de) * 1993-07-29 1997-11-27 Max Planck Gesellschaft Verwendung von Thiolverbindungen zur Therapie von Hepatitis-_Viren-induzierten Erkrankungen
JPH07215801A (ja) * 1994-01-28 1995-08-15 Senju Pharmaceut Co Ltd 肺保存剤および肺保存方法
JPH07330501A (ja) * 1994-06-14 1995-12-19 Senju Pharmaceut Co Ltd 肝保存剤および肝保存方法
DE4439477C2 (de) * 1994-11-08 1999-10-21 Asta Medica Ag Verwendung von R,S-(+/-)-alpha-Liponsäure, R-(+)-alpha-Liponäure, S-(-)-alpha-Liponsäure in reduzierter oder oxidierter Form oder der Metabolite sowie deren Salze, Ester, Amide zur Behandlung der diabetischen Mikroangiopathie
DE19706111C2 (de) * 1997-02-17 1999-02-18 Fresenius Medical Care De Gmbh Lösung zur Aufbewahrung von Organen
US5990153A (en) * 1997-05-05 1999-11-23 Wood; John G. Ultrasonicated α-lipoic acid solutions for attenuating microvascular injury
US6045990A (en) * 1998-07-09 2000-04-04 Baust; John M. Inclusion of apoptotic regulators in solutions for cell storage at low temperature
DE19834087C1 (de) * 1998-07-29 2000-03-30 Mirzaie Sedaposhteh Massoud Wäßrige Konservierungslösung und Verfahren zur Aufbewahrung tierischen Gewebes
GB0028414D0 (en) 2000-11-22 2001-01-03 Univ Leeds Flush preservation solution
DE102007026392A1 (de) 2007-06-06 2008-12-11 Bayer Healthcare Ag Lösungen für die Perfusion und Konservierung von Organen und Geweben
GR20180100514A (el) * 2018-11-07 2020-06-15 Πανεπιστημιο Πατρων Φαρμακευτικοι συνδυασμοι και κιτ για την προληψη ή την θεραπεια του πονου και αλλων επιπλοκων της ορθοπαιδικης ή αγγειακης χειρουργικης και του πολλαπλου τραυματος

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987001940A1 (en) * 1985-10-03 1987-04-09 Wisconsin Alumni Research Foundation Perfusate for the preservation of organs

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186253A (en) * 1978-10-10 1980-01-29 The Green Cross Corporation Perfusate for preserving organ to be transplanted and preserving method
US4473552A (en) * 1981-03-16 1984-09-25 Jost Leonora I Anaerobic method for preserving whole blood, tissue and components containing living mammalian cells
US4423600A (en) * 1982-12-10 1984-01-03 Mckenna Joan J Method for preservation of living organic tissue by freezing
SE8403912D0 (sv) * 1984-07-30 1984-07-30 Pharmacia Ab Lekemedelssats eller -komposition
EP0215138B1 (fr) * 1985-09-06 1991-01-16 Societe Des Produits Nestle S.A. Préservation des tissus vivants
US4879283A (en) * 1985-10-03 1989-11-07 Wisconsin Alumni Research Foundation Solution for the preservation of organs
ES2007994A6 (es) * 1988-08-16 1989-07-01 Grino Boira Jose Maria Medio liquido para perfusion y preservacion de organos.
US4920044A (en) * 1988-11-08 1990-04-24 The Cleveland Clinic Foundation Intracellular flush solution for preserving organs
US4938961A (en) * 1989-04-28 1990-07-03 Geoffrey Collins Organ preservation solution containing pokyethylene gycol and method of performing cardioplegia

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987001940A1 (en) * 1985-10-03 1987-04-09 Wisconsin Alumni Research Foundation Perfusate for the preservation of organs

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
A.BLAUSTEIN ET. AL.: "Myocardial glutathione depletion impairs recovery after short periods of ischemia", CIRCULATION, vol. 80, no. 5, October 1989 (1989-10-01), pages 1449 - 1457 *
C.CECONI ET. AL.: "The role of glutathione status in the protection against ischaemic and reperfusion damage: effects of N-acetylcysteine", JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, vol. 20, no. 1, January 1988 (1988-01-01), LONDRES,GB, pages 5 - 13 *
H.TANIGUCHI: "Experimental study on active oxygen species to warm ischaemic lung: Availability of GSH, SOD and allopurinol", ACTA MEDICA NAGASAKI, vol. 34, no. 2-4, 1989, pages 177 - 187 *
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, vol. 22, suppl. V, 1990, abrégé no. P82, Academic Press, Londres, GB; W.N.WICOMB et. al.: *
M.BERNIER ET AL.: "Reperfusion-induced arrhythmias and oxygen-derived free radicals. Studies with", CIRCULATION RESEARCH, vol. 58, no. 3, March 1988 (1988-03-01), pages 331 - 340 *

Also Published As

Publication number Publication date
GB2249937B (en) 1994-02-16
ITMI912991A1 (it) 1993-05-11
DE4138040A1 (de) 1992-05-21
ES2050580A1 (es) 1994-05-16
IT1251995B (it) 1995-05-27
GB9124488D0 (en) 1992-01-08
ES2050580B1 (es) 1994-12-16
CA2055827A1 (en) 1992-05-21
CH683485A5 (fr) 1994-03-31
ATA228791A (de) 1994-10-15
ITMI912991A0 (it) 1991-11-11
AT399440B (de) 1995-05-26
CA2055827C (en) 1999-06-15
GB2249937A (en) 1992-05-27

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Effective date: 20061130