GB9124488D0 - Solutions for the perfusion,preservation and reperfusion of organs - Google Patents

Solutions for the perfusion,preservation and reperfusion of organs

Info

Publication number
GB9124488D0
GB9124488D0 GB919124488A GB9124488A GB9124488D0 GB 9124488 D0 GB9124488 D0 GB 9124488D0 GB 919124488 A GB919124488 A GB 919124488A GB 9124488 A GB9124488 A GB 9124488A GB 9124488 D0 GB9124488 D0 GB 9124488D0
Authority
GB
United Kingdom
Prior art keywords
reperfusion
perfusion
organs
preservation
solutions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB919124488A
Other versions
GB2249937A (en
GB2249937B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur SA
Original Assignee
Pasteur Merieux Serum et Vaccines SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9014424A external-priority patent/FR2669189B1/en
Priority claimed from FR9109027A external-priority patent/FR2679107B1/en
Application filed by Pasteur Merieux Serum et Vaccines SA filed Critical Pasteur Merieux Serum et Vaccines SA
Publication of GB9124488D0 publication Critical patent/GB9124488D0/en
Publication of GB2249937A publication Critical patent/GB2249937A/en
Application granted granted Critical
Publication of GB2249937B publication Critical patent/GB2249937B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0205Chemical aspects
    • A01N1/021Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/14Quaternary ammonium compounds, e.g. edrophonium, choline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A61K31/175Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • A61K38/063Glutathione

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
GB9124488A 1990-11-20 1991-11-18 Solutions for the perfusion, preservation and reperfusion of organs Expired - Lifetime GB2249937B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9014424A FR2669189B1 (en) 1990-11-20 1990-11-20 PERFUSION AND STORAGE SOLUTIONS FOR CARDIAC TRANSPLANTATIONS.
FR9109027A FR2679107B1 (en) 1991-07-17 1991-07-17 ORGANIC PERFUSION, PRESERVATION AND REPERFUSION SOLUTIONS.

Publications (3)

Publication Number Publication Date
GB9124488D0 true GB9124488D0 (en) 1992-01-08
GB2249937A GB2249937A (en) 1992-05-27
GB2249937B GB2249937B (en) 1994-02-16

Family

ID=26228338

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9124488A Expired - Lifetime GB2249937B (en) 1990-11-20 1991-11-18 Solutions for the perfusion, preservation and reperfusion of organs

Country Status (8)

Country Link
AT (1) AT399440B (en)
BE (1) BE1006834A3 (en)
CA (1) CA2055827C (en)
CH (1) CH683485A5 (en)
DE (1) DE4138040A1 (en)
ES (1) ES2050580B1 (en)
GB (1) GB2249937B (en)
IT (1) IT1251995B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1007500A3 (en) * 1992-09-18 1995-07-18 Pasteur Merieux Serums Vacc Solution infusion, conservation and organ reperfusion.
WO1994026103A1 (en) * 1993-05-07 1994-11-24 Chugai Seiyaku Kabushiki Kaisha Organ preservative
DE4325547C2 (en) * 1993-07-29 1997-11-27 Max Planck Gesellschaft Use of thiol compounds for the therapy of hepatitis-virus-induced diseases
JPH07215801A (en) * 1994-01-28 1995-08-15 Senju Pharmaceut Co Ltd Preservative for lung and method for preserving lung
JPH07330501A (en) * 1994-06-14 1995-12-19 Senju Pharmaceut Co Ltd Liver-preserving agent and liver preserving method
DE4439477C2 (en) * 1994-11-08 1999-10-21 Asta Medica Ag Use of R, S - (+/-) - alpha-lipoic acid, R - (+) - alpha-lipoic acid, S - (-) - alpha-lipoic acid in reduced or oxidized form or the metabolites and their salts, esters, amides for the treatment of diabetic microangiopathy
DE19706111C2 (en) * 1997-02-17 1999-02-18 Fresenius Medical Care De Gmbh Solution for storage of organs
US5990153A (en) * 1997-05-05 1999-11-23 Wood; John G. Ultrasonicated α-lipoic acid solutions for attenuating microvascular injury
US6045990A (en) * 1998-07-09 2000-04-04 Baust; John M. Inclusion of apoptotic regulators in solutions for cell storage at low temperature
DE19834087C1 (en) * 1998-07-29 2000-03-30 Mirzaie Sedaposhteh Massoud Aqueous preservative solution for storage of animal tissue, especially porcine heart valves, contains sodium, potassium, magnesium and calcium salts, glucose and chelate former
GB0028414D0 (en) 2000-11-22 2001-01-03 Univ Leeds Flush preservation solution
DE102007026392A1 (en) 2007-06-06 2008-12-11 Bayer Healthcare Ag Solutions for the perfusion and preservation of organs and tissues
GR20180100514A (en) * 2018-11-07 2020-06-15 Πανεπιστημιο Πατρων Pharmaceutical combinations and kits for the prevention or therapy of pain and other complications of orthopedic or vascular surgery and multiple trauma

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186253A (en) * 1978-10-10 1980-01-29 The Green Cross Corporation Perfusate for preserving organ to be transplanted and preserving method
US4473552A (en) * 1981-03-16 1984-09-25 Jost Leonora I Anaerobic method for preserving whole blood, tissue and components containing living mammalian cells
US4423600A (en) * 1982-12-10 1984-01-03 Mckenna Joan J Method for preservation of living organic tissue by freezing
SE8403912D0 (en) * 1984-07-30 1984-07-30 Pharmacia Ab PHARMACEUTICAL KIT OR COMPOSITION
DE3581407D1 (en) * 1985-09-06 1991-02-21 Nestle Sa STORAGE OF LIVING TISSUE.
US4879283A (en) * 1985-10-03 1989-11-07 Wisconsin Alumni Research Foundation Solution for the preservation of organs
US4798824A (en) * 1985-10-03 1989-01-17 Wisconsin Alumni Research Foundation Perfusate for the preservation of organs
ES2007994A6 (en) * 1988-08-16 1989-07-01 Grino Boira Jose Maria Liquid medium for infusion and preservation of organs.
US4920044A (en) * 1988-11-08 1990-04-24 The Cleveland Clinic Foundation Intracellular flush solution for preserving organs
US4938961A (en) * 1989-04-28 1990-07-03 Geoffrey Collins Organ preservation solution containing pokyethylene gycol and method of performing cardioplegia

Also Published As

Publication number Publication date
ITMI912991A1 (en) 1993-05-11
ITMI912991A0 (en) 1991-11-11
CA2055827C (en) 1999-06-15
BE1006834A3 (en) 1995-01-03
GB2249937A (en) 1992-05-27
AT399440B (en) 1995-05-26
GB2249937B (en) 1994-02-16
DE4138040A1 (en) 1992-05-21
ES2050580B1 (en) 1994-12-16
CH683485A5 (en) 1994-03-31
IT1251995B (en) 1995-05-27
CA2055827A1 (en) 1992-05-21
ES2050580A1 (en) 1994-05-16
ATA228791A (en) 1994-10-15

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Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
PE20 Patent expired after termination of 20 years

Expiry date: 20111117