AU774234B2 - Steroids, their preparation, pharmaceutical compositions thereof and uses of the compounds - Google Patents

Steroids, their preparation, pharmaceutical compositions thereof and uses of the compounds Download PDF

Info

Publication number
AU774234B2
AU774234B2 AU68167/00A AU6816700A AU774234B2 AU 774234 B2 AU774234 B2 AU 774234B2 AU 68167/00 A AU68167/00 A AU 68167/00A AU 6816700 A AU6816700 A AU 6816700A AU 774234 B2 AU774234 B2 AU 774234B2
Authority
AU
Australia
Prior art keywords
formula
compound
hydroxy
phenyl
propinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU68167/00A
Other languages
English (en)
Other versions
AU6816700A (en
Inventor
Lianzhi Chen
Wenliang Chen
Mingwei Wang
Zhengyu Ye
Lin Zuo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SINIWEST HOLDINGS Inc
Shanghai Zhongxi Pharmaceutical Co Ltd
Zhejiang Xianju Pharmaceutical Co Ltd
Original Assignee
SHANGHAI SINIWEST PHARMACEUTIC
Shanghai Zhongxi Pharmaceutical Co Ltd
Zhejiang Xianju Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SHANGHAI SINIWEST PHARMACEUTIC, Shanghai Zhongxi Pharmaceutical Co Ltd, Zhejiang Xianju Pharmaceutical Co Ltd filed Critical SHANGHAI SINIWEST PHARMACEUTIC
Publication of AU6816700A publication Critical patent/AU6816700A/en
Application granted granted Critical
Publication of AU774234B2 publication Critical patent/AU774234B2/en
Assigned to XIANJU PHARMACEUTICAL CO., LTD., SINIWEST HOLDINGS, INC., SHANGHAI ZHONGXI PHARMACEUTICAL CO., LTD. reassignment XIANJU PHARMACEUTICAL CO., LTD. Amend patent request/document other than specification (104) Assignors: SHANGHAI SINIWEST PHARMACEUTICAL CHEMICAL TECHNOLOGY CO., LTD., SHANGHAI ZHONGXI PHARMACEUTICAL CO., LTD., XIANJU PHARMACEUTICAL CO., LTD.
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU68167/00A 1999-09-02 2000-08-31 Steroids, their preparation, pharmaceutical compositions thereof and uses of the compounds Expired AU774234B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN99116829 1999-09-02
CN99116829A CN1117759C (zh) 1999-09-02 1999-09-02 甾体化合物,其制备方法和其药物组合物及其应用
PCT/CN2000/000255 WO2001018026A1 (en) 1999-09-02 2000-08-31 Steroids, their preparation, pharmaceutical compositions thereof and uses of the compounds

Publications (2)

Publication Number Publication Date
AU6816700A AU6816700A (en) 2001-04-10
AU774234B2 true AU774234B2 (en) 2004-06-17

Family

ID=5279500

Family Applications (1)

Application Number Title Priority Date Filing Date
AU68167/00A Expired AU774234B2 (en) 1999-09-02 2000-08-31 Steroids, their preparation, pharmaceutical compositions thereof and uses of the compounds

Country Status (15)

Country Link
US (1) US6514956B1 (enExample)
EP (1) EP1219632B1 (enExample)
JP (2) JP4002438B2 (enExample)
CN (1) CN1117759C (enExample)
AT (1) ATE343585T1 (enExample)
AU (1) AU774234B2 (enExample)
CA (1) CA2382106C (enExample)
CY (1) CY1105798T1 (enExample)
DE (1) DE60031557T2 (enExample)
DK (1) DK1219632T3 (enExample)
ES (1) ES2273724T3 (enExample)
GB (1) GB2358398B8 (enExample)
IL (2) IL147927A0 (enExample)
PT (1) PT1219632E (enExample)
WO (1) WO2001018026A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6064445A (en) * 1996-11-28 2000-05-16 Samsung Electronics Co., Ltd. Automatic picture size control method for semiwide-screen television receiver
CN100588393C (zh) * 2004-12-15 2010-02-10 上海三合生物技术有限公司 赛米司酮类用于治疗抑郁症的用途
CN1899289A (zh) 2005-07-22 2007-01-24 上海三合生物技术有限公司 赛米司酮类化合物用于治疗艾滋病的用途
CN103110590B (zh) * 2009-12-29 2015-07-01 上海中西制药有限公司 赛米司酮固体制剂及其制备方法
CN103083324B (zh) * 2011-11-01 2016-03-02 贾力 干预循环肿瘤细胞粘附和浸润到外周组织的药物和新方法
CN111040013A (zh) * 2019-12-21 2020-04-21 长沙霍滋生物科技有限公司 一种类固醇衍生物及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA8231B (en) * 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
DE3625315A1 (de) * 1986-07-25 1988-01-28 Schering Ag 11ss-(4-isopropenylphenyl)-estra-4,9-diene, deren herstellung und diese enthaltende pharmazeutische praeparate
US5272140A (en) * 1987-01-23 1993-12-21 Akzo N.V. 11-aryl steroid derivatives
EP0289073B1 (en) * 1987-04-24 1991-11-27 Akzo N.V. Novel 11-aryloestrane and 11-arylpregnane derivatives

Also Published As

Publication number Publication date
GB2358398B8 (en) 2005-11-11
GB2358398B (en) 2004-12-15
DE60031557T2 (de) 2007-08-30
ATE343585T1 (de) 2006-11-15
EP1219632A4 (en) 2003-01-02
CN1287123A (zh) 2001-03-14
CA2382106C (en) 2007-10-30
AU6816700A (en) 2001-04-10
GB2358398A (en) 2001-07-25
EP1219632B1 (en) 2006-10-25
GB0110793D0 (en) 2001-06-27
IL147927A (en) 2006-08-01
JP4002438B2 (ja) 2007-10-31
IL147927A0 (en) 2002-08-14
PT1219632E (pt) 2006-12-29
JP2003523946A (ja) 2003-08-12
DK1219632T3 (da) 2006-12-04
US6514956B1 (en) 2003-02-04
EP1219632A1 (en) 2002-07-03
WO2001018026A1 (en) 2001-03-15
DE60031557D1 (de) 2006-12-07
JP2007210994A (ja) 2007-08-23
CN1117759C (zh) 2003-08-13
CY1105798T1 (el) 2011-02-02
ES2273724T3 (es) 2007-05-16
CA2382106A1 (en) 2001-03-15

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase
TH Corrigenda

Free format text: IN VOL 15, NO 26, PAGE(S) 5475-5478 UNDER THE HEADING APPLICATIONS LAPSED, REFUSED OR WITHDRAWN PLEASE DELETE ALL REFERENCE TO APPLICATION NO. 68167/00

FGA Letters patent sealed or granted (standard patent)
SREP Specification republished
TC Change of applicant's name (sec. 104)

Owner name: SHANGHAI ZHONGXI PHARMACEUTICAL CO., LTD., XIANJU

Free format text: FORMER NAME: SHANGHAI ZHONGXI PHARMACEUTICAL CO., LTD., XIANJU PHARMACEUTICAL CO., LTD., SHANGHAI SINIWEST PHARMACEUTICAL CHEMICAL TECHNOLOGY CO., LTD.

TH Corrigenda

Free format text: IN VOL 18, NO 23, PAGE(S) 671 UNDER THE HEADING APPLICATIONS ACCEPTED - NAME INDEX IN THE NAME OF SHANGHAI ZHONGXI PHARMACEUTICAL CO., LTD., XIANJU PHARMACEUTICAL CO., LTD., SHANGHAI SINIWEST PHARMACEUTICAL CHEMICAL TECHNOLOGY CO., LTD., SERIAL NO. 774234, INID (71), AMEND THE THIRD NAMED APPLICANT TO READ SINIWEST HOLDINGS, INC.

MK14 Patent ceased section 143(a) (annual fees not paid) or expired