AU762047B2 - Insulin-like growth factor (IGF) I mutant variants - Google Patents
Insulin-like growth factor (IGF) I mutant variants Download PDFInfo
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- AU762047B2 AU762047B2 AU27194/00A AU2719400A AU762047B2 AU 762047 B2 AU762047 B2 AU 762047B2 AU 27194/00 A AU27194/00 A AU 27194/00A AU 2719400 A AU2719400 A AU 2719400A AU 762047 B2 AU762047 B2 AU 762047B2
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| AUPR030900A0 (en) | 2000-09-22 | 2000-10-12 | Queensland University Of Technology | Growth factor complex |
| ES2207387B1 (es) * | 2002-02-28 | 2005-07-16 | Consejo Sup. Investig. Cientificas | Composicion quimica de igf-i para el tratamiento y prevencion de enfermedades neurodegenerativas. |
| WO2004027064A2 (en) * | 2002-09-18 | 2004-04-01 | Centre Hospitalier De L'universite De Montreal (Chum) | Ghrh analogues |
| TWI353991B (en) | 2003-05-06 | 2011-12-11 | Syntonix Pharmaceuticals Inc | Immunoglobulin chimeric monomer-dimer hybrids |
| CN1870893A (zh) | 2003-09-12 | 2006-11-29 | 特西卡股份有限公司 | 胰岛素样生长因子－1(igf－1)缺陷的治疗方法 |
| WO2005033134A2 (en) * | 2003-09-30 | 2005-04-14 | Regeneron Pharmaceuticals, Inc. | Secreted protein therapeutics and uses thereof |
| CA2545603A1 (en) | 2003-11-12 | 2005-05-26 | Biogen Idec Ma Inc. | Neonatal fc receptor (fcrn)-binding polypeptide variants, dimeric fc binding proteins and methods related thereto |
| GB0426154D0 (en) * | 2004-11-29 | 2004-12-29 | European Molecular Biology Lab Embl | IGF-1 novel peptides |
| US7833513B2 (en) | 2004-12-03 | 2010-11-16 | Rhode Island Hospital | Treatment of Alzheimer's Disease |
| EP1674113A1 (en) * | 2004-12-22 | 2006-06-28 | F. Hoffmann-La Roche Ag | Conjugates of insulin-like growth factor-1 (IGF-1) and poly(ethylene glycol) |
| EP2311880A3 (en) | 2005-01-05 | 2011-07-27 | Biogen Idec MA Inc. | Cripto binding molecules |
| EP1841443A4 (en) * | 2005-01-11 | 2012-05-02 | Heart Failure Technologies Inc | METHOD AND SYSTEM FOR TREATING HEART ERRORS |
| TWI406870B (zh) * | 2005-02-21 | 2013-09-01 | Chugai Pharmaceutical Co Ltd | A method of making a protein using hamster IGF-1 |
| FR2892174B1 (fr) | 2005-10-14 | 2007-12-28 | Vallourec Mannesmann Oil Gas F | Element filete tubulaire muni d'un revetement protecteur sec |
| CL2007002502A1 (es) | 2006-08-31 | 2008-05-30 | Hoffmann La Roche | Variantes del factor de crecimiento similar a insulina-1 humano (igf-1) pegilados en lisina; metodo de produccion; proteina de fusion que la comprende; y su uso para tratar la enfermedad de alzheimer. |
| KR101106795B1 (ko) * | 2006-08-31 | 2012-01-18 | 에프. 호프만-라 로슈 아게 | 인슐린-유사 성장 인자-ｉ의 제조 방법 |
| MX2010010495A (es) * | 2008-04-03 | 2010-10-15 | Hoffmann La Roche | Uso de variantes del factor de crecimiento similar a la insulina (igf-i) pegiladas para el tratamiento de trastornos neuromusculares. |
| CN101965516A (zh) * | 2008-04-03 | 2011-02-02 | 弗·哈夫曼-拉罗切有限公司 | 聚乙二醇化胰岛素样生长因子测定 |
| EP2341940A1 (en) * | 2008-07-16 | 2011-07-13 | Arecor Limited | The stabilisation of proteins |
| WO2010094906A1 (en) * | 2009-07-16 | 2010-08-26 | Arecor Limited | The stabilisation of proteins |
| EP2328607A1 (en) * | 2008-07-16 | 2011-06-08 | Arecor Limited | Stable formulation of a therapeutic protein |
| JP5571186B2 (ja) * | 2009-07-22 | 2014-08-13 | イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ | ５９位にアミノ酸置換を有するインスリン様増殖因子−１（ｉｇｆ−１）の類似体 |
| CN102906104B (zh) * | 2009-09-10 | 2015-04-22 | 朗萨生物制剂有限公司 | 用于多肽纯化的方法和系统 |
| US20110152188A1 (en) * | 2009-12-23 | 2011-06-23 | Hanns-Christian Mahler | Pharmaceutical compositions of igf/i proteins |
| JP6200806B2 (ja) | 2010-05-21 | 2017-09-20 | メリマック ファーマシューティカルズ インコーポレーティッド | 二重特異的融合タンパク質 |
| WO2012006635A1 (en) | 2010-07-09 | 2012-01-12 | Biogen Idec Hemophilia Inc. | Processable single chain molecules and polypeptides made using same |
| WO2013012733A1 (en) | 2011-07-15 | 2013-01-24 | Biogen Idec Ma Inc. | Heterodimeric fc regions, binding molecules comprising same, and methods relating thereto |
| DK2802606T3 (en) | 2012-01-10 | 2018-06-25 | Biogen Ma Inc | INCREASE TRANSPORT OF THERAPEUTIC MOLECULES OVER THE BLOOD-BRAIN BARRIER |
| EP3626735A1 (en) * | 2012-12-18 | 2020-03-25 | Novartis AG | Stabilized insulin-like growth factor polypeptides |
| EA037906B1 (ru) | 2013-03-15 | 2021-06-04 | Биовератив Терапьютикс Инк. | Препараты полипептида фактора ix |
| PE20171766A1 (es) | 2015-02-04 | 2017-12-21 | Hoffmann La Roche | Oligomeros antisentido de tau y usos de estos |
| WO2016127000A1 (en) | 2015-02-04 | 2016-08-11 | Bristol-Myers Squibb Company | Methods of selecting therapeutic molecules |
| US10040840B2 (en) | 2015-10-02 | 2018-08-07 | Silver Creek Pharmaceuticals, Inc. | Bi-specific annexin A5/IGF-1 proteins and methods of use thereof to promote regeneration and survival of tissue |
| EP3453722A1 (en) * | 2017-09-06 | 2019-03-13 | Julius-Maximilians-Universität Würzburg | Pharmaceuticals and devices for the covalent immobilization to the extracellular matrix by transglutaminase |
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2001
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2003
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2005
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2007
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2009
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989005822A1 (en) * | 1987-12-24 | 1989-06-29 | Gropep Pty. Ltd. | Peptide analogues of insulin-like growth factor 1 (igf-1) or factor 2 (igf-2) |
Non-Patent Citations (2)
| Title |
|---|
| BIOCHEMISTRY 36: 4108-4117 * |
| J.MOL.ENDOCRINOLOGY 8: 29-41 * |
Also Published As
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| ES2329220T3 (es) | 2009-11-24 |
| US20030191065A1 (en) | 2003-10-09 |
| JP2007045829A (ja) | 2007-02-22 |
| US20040033952A1 (en) | 2004-02-19 |
| IL186608A (en) | 2014-06-30 |
| WO2000040612A9 (en) | 2001-03-22 |
| AU2719400A (en) | 2000-07-24 |
| CA2356257A1 (en) | 2000-07-13 |
| JP2005139203A (ja) | 2005-06-02 |
| US6506874B1 (en) | 2003-01-14 |
| IL186608A0 (en) | 2008-01-20 |
| PT1141015E (pt) | 2009-10-13 |
| JP4467549B2 (ja) | 2010-05-26 |
| JP2002535967A (ja) | 2002-10-29 |
| US6509443B1 (en) | 2003-01-21 |
| DK1141015T3 (da) | 2010-01-25 |
| IL143834A0 (en) | 2002-04-21 |
| DE60042550D1 (de) | 2009-08-27 |
| WO2000040612A1 (en) | 2000-07-13 |
| US20040023883A1 (en) | 2004-02-05 |
| IL143834A (en) | 2008-07-08 |
| CY1109452T1 (el) | 2014-08-13 |
| CA2356257C (en) | 2012-10-16 |
| US20040033951A1 (en) | 2004-02-19 |
| EP1141015A1 (en) | 2001-10-10 |
| EP1141015B1 (en) | 2009-07-15 |
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