EA201270403A1 - Способ и система для очистки полипептидов - Google Patents
Способ и система для очистки полипептидовInfo
- Publication number
- EA201270403A1 EA201270403A1 EA201270403A EA201270403A EA201270403A1 EA 201270403 A1 EA201270403 A1 EA 201270403A1 EA 201270403 A EA201270403 A EA 201270403A EA 201270403 A EA201270403 A EA 201270403A EA 201270403 A1 EA201270403 A1 EA 201270403A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- polypeptides
- cleaning
- purification
- relates
- solutions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/16—Feed pretreatment
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Water Supply & Treatment (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Peptides Or Proteins (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Изобретение относится к способу и автоматизированной системе очистки полипептидов, которые включают прямое фильтрование растворов, содержащих полипептиды, после очистки.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09169911 | 2009-09-10 | ||
PCT/EP2010/063295 WO2011029898A1 (en) | 2009-09-10 | 2010-09-10 | Method and system for polypeptide purification |
Publications (1)
Publication Number | Publication Date |
---|---|
EA201270403A1 true EA201270403A1 (ru) | 2012-08-30 |
Family
ID=41786140
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201270403A EA201270403A1 (ru) | 2009-09-10 | 2010-09-10 | Способ и система для очистки полипептидов |
Country Status (17)
Country | Link |
---|---|
US (2) | US8906231B2 (ru) |
EP (1) | EP2475678B1 (ru) |
JP (1) | JP5570600B2 (ru) |
KR (1) | KR20120065383A (ru) |
CN (2) | CN104774242A (ru) |
AU (1) | AU2010294192A1 (ru) |
BR (1) | BR112012005485A2 (ru) |
CA (1) | CA2773428A1 (ru) |
EA (1) | EA201270403A1 (ru) |
ES (1) | ES2526876T3 (ru) |
HK (1) | HK1211954A1 (ru) |
IL (1) | IL218244A0 (ru) |
MX (1) | MX2012002901A (ru) |
NZ (1) | NZ598381A (ru) |
SG (1) | SG178483A1 (ru) |
WO (1) | WO2011029898A1 (ru) |
ZA (1) | ZA201201436B (ru) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2012002901A (es) * | 2009-09-10 | 2012-06-27 | Lonza Biologics Plc | Metodo y sistema para purificacion de polipeptidos. |
CN108226317B (zh) * | 2016-12-21 | 2020-10-20 | 复旦大学 | 一种基于细胞层面进行全蛋白质组学分析的方法 |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL76360A0 (en) | 1984-09-26 | 1986-01-31 | Takeda Chemical Industries Ltd | Mutual separation of proteins |
WO1986007063A1 (en) * | 1985-05-21 | 1986-12-04 | Takeda Chemical Industries, Ltd. | Mutual separation of proteins |
WO1986002068A1 (en) * | 1984-09-26 | 1986-04-10 | Takeda Chemical Industries, Ltd. | Mutual separation of proteins |
GB2173125B (en) * | 1985-04-04 | 1989-04-19 | Mueszeripari Muevek Lab | Apparatus for overpressured thin-layer chromatographic technique |
US4721572A (en) * | 1985-07-12 | 1988-01-26 | Miles Laboratories, Inc. | Purfication of blood clotting factors and other blood proteins on non-carbohydrate sulfated matrices |
US4980130A (en) * | 1986-12-16 | 1990-12-25 | Ciba-Geigy Corporation | System for preparation of samples for analysis |
US5091092A (en) * | 1989-05-03 | 1992-02-25 | Analytical Bio-Chemistry Laboratories, Inc. | Single-loop chromatography system and method |
US5228989A (en) * | 1989-07-06 | 1993-07-20 | Perseptive Biosystems, Inc. | Perfusive chromatography |
US5252296A (en) * | 1990-05-15 | 1993-10-12 | Chiron Corporation | Method and apparatus for biopolymer synthesis |
US5250660A (en) * | 1991-11-12 | 1993-10-05 | Eli Lilly And Company | Peptide purification process |
IT1258959B (it) * | 1992-06-09 | 1996-03-11 | Impianto a moduli mobili per lo sviluppo e la produzione di prodotti biotecnologici su scala pilota | |
US5366620A (en) * | 1993-04-01 | 1994-11-22 | Upchurch Scientific, Inc. | Inlet filter |
US6372425B1 (en) * | 1994-10-26 | 2002-04-16 | Merck & Co., Inc. | Large scale affinity chromatography of macromolecules |
EP0814900B1 (en) * | 1995-03-07 | 2001-09-12 | B.B.I. Bioseq, Inc. | Method of controlling enzymatic reactions |
US6168948B1 (en) * | 1995-06-29 | 2001-01-02 | Affymetrix, Inc. | Miniaturized genetic analysis systems and methods |
US5856174A (en) * | 1995-06-29 | 1999-01-05 | Affymetrix, Inc. | Integrated nucleic acid diagnostic device |
US20020068357A1 (en) * | 1995-09-28 | 2002-06-06 | Mathies Richard A. | Miniaturized integrated nucleic acid processing and analysis device and method |
US5906747A (en) * | 1995-11-13 | 1999-05-25 | Biosepra Inc. | Separation of molecules from dilute solutions using composite chromatography media having high dynamic sorptive capacity at high flow rates |
GB9703369D0 (en) * | 1997-02-18 | 1997-04-09 | Lindqvist Bjorn H | Process |
NZ337795A (en) * | 1997-03-17 | 2001-06-29 | Human Genome Sciences Inc | Death domain containing receptor 5 and it's use in the treatment of DR5 related disease |
EP0998486B2 (en) * | 1997-06-13 | 2012-02-01 | Genentech, Inc. | Protein recovery by chromatography followed by filtration upon a charged layer |
WO2000040612A1 (en) * | 1999-01-06 | 2000-07-13 | Genentech, Inc. | Insulin-like growth factor (igf) i mutant variants |
DK1141014T3 (da) | 1999-01-06 | 2005-04-11 | Genentech Inc | Insulinlignende vækstfaktor (IGF) i mutantvariant |
JP4063671B2 (ja) * | 2001-02-16 | 2008-03-19 | ピードモント・レナル・クリニクス・ピー・エイ | 透析液のイン・ライン滅菌を用いる自動腹膜透析システムおよび方法 |
AU784808B2 (en) * | 2001-04-02 | 2006-06-29 | Kedrion Melville Inc. | Prion and viral clearance process |
US20030153729A1 (en) * | 2001-12-28 | 2003-08-14 | Duewel Henry S. | Enzyme/chemical reactor based protein processing method for proteomics analysis by mass spectrometry |
US7074327B2 (en) * | 2003-05-08 | 2006-07-11 | Nanostream, Inc. | Sample preparation for parallel chromatography |
US7790025B2 (en) * | 2003-05-16 | 2010-09-07 | Cryobiophysica, Inc. | External gradient chromatofocusing |
ATE465172T1 (de) * | 2004-03-05 | 2010-05-15 | Univ Illinois | Peptidträger für die verabreichung von arzneimitteln |
DE102005028897A1 (de) * | 2005-06-17 | 2006-12-28 | Eckert & Ziegler Eurotope Gmbh | Anordnung und Verfahren zur Verarbeitung von chemischen Stoffen, Computerprogramm zur Steuerung einer solchen Anordnung sowie ein entsprechendes computerlesbares Speichermedium |
WO2008085988A1 (en) * | 2007-01-05 | 2008-07-17 | Amgen Inc. | Methods of purifying proteins |
US7999084B2 (en) * | 2007-05-16 | 2011-08-16 | Agilent Technologies, Inc. | Devices and methods for reducing matrix effects |
EP3006934B1 (en) * | 2008-08-01 | 2017-02-01 | BioVentures, Inc., | Device for the purification, isolation, desalting or buffer/solvent exchange of substances |
WO2011028753A1 (en) * | 2009-09-01 | 2011-03-10 | Genentech, Inc. | Enhanced protein purification through a modified protein a elution |
MX2012002901A (es) * | 2009-09-10 | 2012-06-27 | Lonza Biologics Plc | Metodo y sistema para purificacion de polipeptidos. |
-
2010
- 2010-09-10 MX MX2012002901A patent/MX2012002901A/es not_active Application Discontinuation
- 2010-09-10 NZ NZ598381A patent/NZ598381A/xx not_active IP Right Cessation
- 2010-09-10 WO PCT/EP2010/063295 patent/WO2011029898A1/en active Application Filing
- 2010-09-10 SG SG2012011268A patent/SG178483A1/en unknown
- 2010-09-10 CA CA2773428A patent/CA2773428A1/en not_active Abandoned
- 2010-09-10 JP JP2012528368A patent/JP5570600B2/ja not_active Expired - Fee Related
- 2010-09-10 EP EP10751950.6A patent/EP2475678B1/en not_active Not-in-force
- 2010-09-10 BR BR112012005485A patent/BR112012005485A2/pt not_active Application Discontinuation
- 2010-09-10 US US13/394,560 patent/US8906231B2/en not_active Expired - Fee Related
- 2010-09-10 AU AU2010294192A patent/AU2010294192A1/en not_active Abandoned
- 2010-09-10 ES ES10751950.6T patent/ES2526876T3/es active Active
- 2010-09-10 EA EA201270403A patent/EA201270403A1/ru unknown
- 2010-09-10 CN CN201510105706.9A patent/CN104774242A/zh active Pending
- 2010-09-10 CN CN201080040450.3A patent/CN102906104B/zh not_active Expired - Fee Related
- 2010-09-10 KR KR1020127009031A patent/KR20120065383A/ko not_active Application Discontinuation
-
2012
- 2012-02-22 IL IL218244A patent/IL218244A0/en unknown
- 2012-02-27 ZA ZA2012/01436A patent/ZA201201436B/en unknown
-
2014
- 2014-10-28 US US14/525,561 patent/US10221209B2/en not_active Expired - Fee Related
-
2015
- 2015-12-30 HK HK15112814.2A patent/HK1211954A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
HK1211954A1 (en) | 2016-06-03 |
SG178483A1 (en) | 2012-04-27 |
WO2011029898A1 (en) | 2011-03-17 |
MX2012002901A (es) | 2012-06-27 |
US20150105542A1 (en) | 2015-04-16 |
NZ598381A (en) | 2013-10-25 |
BR112012005485A2 (pt) | 2016-04-19 |
EP2475678A1 (en) | 2012-07-18 |
EP2475678B1 (en) | 2014-10-08 |
ES2526876T3 (es) | 2015-01-16 |
US20120253024A1 (en) | 2012-10-04 |
JP5570600B2 (ja) | 2014-08-13 |
US8906231B2 (en) | 2014-12-09 |
JP2013504750A (ja) | 2013-02-07 |
CA2773428A1 (en) | 2011-03-17 |
US10221209B2 (en) | 2019-03-05 |
CN102906104A (zh) | 2013-01-30 |
KR20120065383A (ko) | 2012-06-20 |
IL218244A0 (en) | 2012-04-30 |
AU2010294192A1 (en) | 2012-04-05 |
CN104774242A (zh) | 2015-07-15 |
ZA201201436B (en) | 2013-05-29 |
CN102906104B (zh) | 2015-04-22 |
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