AU755944B2 - Use of epothilones for the treatment of cancer - Google Patents

Use of epothilones for the treatment of cancer Download PDF

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Publication number
AU755944B2
AU755944B2 AU29279/99A AU2927999A AU755944B2 AU 755944 B2 AU755944 B2 AU 755944B2 AU 29279/99 A AU29279/99 A AU 29279/99A AU 2927999 A AU2927999 A AU 2927999A AU 755944 B2 AU755944 B2 AU 755944B2
Authority
AU
Australia
Prior art keywords
epothilone
tumor
treatment
dose
administered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU29279/99A
Other languages
English (en)
Other versions
AU2927999A (en
Inventor
Pamela Cohen
Manuel Litchman
Terence O'reilly
Markus Wartmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9803905.0A external-priority patent/GB9803905D0/en
Priority claimed from GBGB9803907.6A external-priority patent/GB9803907D0/en
Priority claimed from GBGB9805936.3A external-priority patent/GB9805936D0/en
Priority claimed from GBGB9805937.1A external-priority patent/GB9805937D0/en
Priority claimed from US09/233,993 external-priority patent/US6302838B1/en
Application filed by Novartis AG filed Critical Novartis AG
Publication of AU2927999A publication Critical patent/AU2927999A/en
Application granted granted Critical
Publication of AU755944B2 publication Critical patent/AU755944B2/en
Priority to AU2003202508A priority Critical patent/AU2003202508B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AU29279/99A 1998-02-25 1999-02-23 Use of epothilones for the treatment of cancer Ceased AU755944B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003202508A AU2003202508B2 (en) 1998-02-25 2003-03-26 Use of epothilones for the treatment of cancer

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
GB9803907 1998-02-25
GBGB9803905.0A GB9803905D0 (en) 1998-02-25 1998-02-25 Organic compounds
GBGB9803907.6A GB9803907D0 (en) 1998-02-25 1998-02-25 Organic compounds
GB9803905 1998-02-25
GBGB9805936.3A GB9805936D0 (en) 1998-03-19 1998-03-19 Organic compounds
GB9805936 1998-03-19
GBGB9805937.1A GB9805937D0 (en) 1998-03-19 1998-03-19 Organic compounds
GB9805937 1998-03-19
US09/233,993 US6302838B1 (en) 1998-02-25 1999-01-19 Cancer treatment with epothilones
US09/233993 1999-01-19
PCT/EP1999/001147 WO1999043320A1 (en) 1998-02-25 1999-02-23 Use of epothilones for the treatment of cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2003202508A Division AU2003202508B2 (en) 1998-02-25 2003-03-26 Use of epothilones for the treatment of cancer

Publications (2)

Publication Number Publication Date
AU2927999A AU2927999A (en) 1999-09-15
AU755944B2 true AU755944B2 (en) 2003-01-02

Family

ID=27517450

Family Applications (1)

Application Number Title Priority Date Filing Date
AU29279/99A Ceased AU755944B2 (en) 1998-02-25 1999-02-23 Use of epothilones for the treatment of cancer

Country Status (10)

Country Link
US (4) US6635666B2 (enExample)
EP (1) EP1056453B1 (enExample)
JP (1) JP2002504511A (enExample)
AU (1) AU755944B2 (enExample)
BE (1) BE1011980A5 (enExample)
CA (1) CA2319752A1 (enExample)
FR (1) FR2775187B1 (enExample)
IT (1) ITMI990375A1 (enExample)
NZ (1) NZ506187A (enExample)
WO (1) WO1999043320A1 (enExample)

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US6498257B1 (en) 1998-04-21 2002-12-24 Bristol-Myers Squibb Company 2,3-olefinic epothilone derivatives
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JP5384777B2 (ja) * 2001-12-18 2014-01-08 有限会社大長企画 強筋肉剤、抗炎症剤
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US7649006B2 (en) 2002-08-23 2010-01-19 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
US6921769B2 (en) 2002-08-23 2005-07-26 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
WO2004018478A2 (en) * 2002-08-23 2004-03-04 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto, analogues and uses thereof
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EP1824458A1 (en) * 2004-11-18 2007-08-29 Bristol-Myers Squibb Company Enteric coated bead comprising epothilone or an epothilone analog, and preparation and administration thereof
BRPI0518286A2 (pt) * 2004-11-18 2008-11-11 Bristol Myers Squibb Co microesfera com revestimento entÉrico contendo ixabepilona e sua preparaÇço
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JP2010510236A (ja) * 2006-11-15 2010-04-02 ダナ−ファーバー キャンサー インスティテュート インク． 安定化させたｍａｍｌペプチドおよびその使用法
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Also Published As

Publication number Publication date
US7875601B2 (en) 2011-01-25
FR2775187B1 (fr) 2003-02-21
US20060223867A1 (en) 2006-10-05
US20020028839A1 (en) 2002-03-07
FR2775187A1 (fr) 1999-08-27
BE1011980A5 (fr) 2000-03-07
US20050165071A1 (en) 2005-07-28
US7091226B2 (en) 2006-08-15
NZ506187A (en) 2003-11-28
US20040024033A1 (en) 2004-02-05
JP2002504511A (ja) 2002-02-12
EP1056453A1 (en) 2000-12-06
EP1056453B1 (en) 2010-10-06
US6635666B2 (en) 2003-10-21
ITMI990375A1 (it) 1999-08-25
WO1999043320A1 (en) 1999-09-02
AU2927999A (en) 1999-09-15
CA2319752A1 (en) 1999-09-02

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