AU7304096A - Novel amine derivatives of epipodophyllotoxin 2", 3"-dideoxyglycosides, preparation method therefor and use thereof as a drug and for treating cancer - Google Patents

Novel amine derivatives of epipodophyllotoxin 2", 3"-dideoxyglycosides, preparation method therefor and use thereof as a drug and for treating cancer Download PDF

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Publication number
AU7304096A
AU7304096A AU73040/96A AU7304096A AU7304096A AU 7304096 A AU7304096 A AU 7304096A AU 73040/96 A AU73040/96 A AU 73040/96A AU 7304096 A AU7304096 A AU 7304096A AU 7304096 A AU7304096 A AU 7304096A
Authority
AU
Australia
Prior art keywords
compound
demethyl
ethylidene
epipodophyllotoxin
dideoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU73040/96A
Other languages
English (en)
Inventor
Laurent Daley
Yves Guminski
Bridget Hill
Thierry Imbert
Claude Monneret
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Publication of AU7304096A publication Critical patent/AU7304096A/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AU73040/96A 1995-10-12 1996-10-11 Novel amine derivatives of epipodophyllotoxin 2", 3"-dideoxyglycosides, preparation method therefor and use thereof as a drug and for treating cancer Abandoned AU7304096A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9511978A FR2739857B1 (fr) 1995-10-12 1995-10-12 Nouveaux derives amines de 2",3"-didesoxyglycosides d'epipodophyllotoxine, leur procede de preparation, leur utilisation comme medicament et leur utilisation destinee aux traitements anticancereux
FR9511978 1995-10-12
PCT/FR1996/001588 WO1997013776A2 (fr) 1995-10-12 1996-10-11 Nouveaux derives amines de 2', 3' didesoxyglycosides d'epipodophyllotoxine, leur procede de preparation, leur utilisation comme medicament et leur utilisation destinee aux traitements anticancereux

Publications (1)

Publication Number Publication Date
AU7304096A true AU7304096A (en) 1997-04-30

Family

ID=9483465

Family Applications (1)

Application Number Title Priority Date Filing Date
AU73040/96A Abandoned AU7304096A (en) 1995-10-12 1996-10-11 Novel amine derivatives of epipodophyllotoxin 2", 3"-dideoxyglycosides, preparation method therefor and use thereof as a drug and for treating cancer

Country Status (10)

Country Link
EP (1) EP0873347A2 (ja)
JP (1) JP2000505053A (ja)
KR (1) KR19990064166A (ja)
CN (1) CN1202173A (ja)
AU (1) AU7304096A (ja)
BR (1) BR9610851A (ja)
CA (1) CA2234484A1 (ja)
FR (1) FR2739857B1 (ja)
NZ (1) NZ320323A (ja)
WO (1) WO1997013776A2 (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2800374B1 (fr) * 1999-10-28 2002-06-28 Adir Nouveaux derives de 9-(3,5-dimethoxyphenyl)-5,8,8a,9- tetrahydrofuro[3',4':6,7]naphto[2,3-d] [1,3]dioxol-6(5ah)- one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
TWI307341B (en) * 2002-10-11 2009-03-11 Plantaceutica Inc Anticancer compounds
FR2859208B1 (fr) 2003-09-02 2006-01-21 Servier Lab Nouveaux derives de 9-amino-podophyllotoxine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN102115483B (zh) * 2009-12-30 2014-12-17 苏州天人合生物技术有限公司 卤代双去氧糖衍生物及其制备方法与应用
CN109369667B (zh) * 2018-12-05 2021-04-13 南通大学 2,3,6-三脱氧糖基去甲表鬼臼毒素化合物及其制备方法和用途
CN110294764B (zh) * 2019-07-15 2021-04-20 中国科学院兰州化学物理研究所 一种偶氮键连接的鬼臼毒素衍生物及其制备方法
CN112079879B (zh) * 2020-08-21 2022-01-14 华润双鹤药业股份有限公司沧州分公司 一种替尼泊苷中间体的合成新方法及替尼泊苷的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6032799A (ja) * 1983-07-29 1985-02-19 Microbial Chem Res Found 新規4′−デメチル−4−エピポドフィロトキシン誘導体
US5066645A (en) * 1989-09-01 1991-11-19 Bristol-Myers Company Epipodophyllotoxin altroside derivatives

Also Published As

Publication number Publication date
WO1997013776A2 (fr) 1997-04-17
CN1202173A (zh) 1998-12-16
JP2000505053A (ja) 2000-04-25
MX9802933A (es) 1998-11-29
FR2739857A1 (fr) 1997-04-18
KR19990064166A (ko) 1999-07-26
CA2234484A1 (fr) 1997-04-17
EP0873347A2 (fr) 1998-10-28
WO1997013776A3 (fr) 1997-06-05
BR9610851A (pt) 1999-07-13
NZ320323A (en) 1999-07-29
FR2739857B1 (fr) 1998-01-02

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted