FR2739857B1 - Nouveaux derives amines de 2",3"-didesoxyglycosides d'epipodophyllotoxine, leur procede de preparation, leur utilisation comme medicament et leur utilisation destinee aux traitements anticancereux - Google Patents

Nouveaux derives amines de 2",3"-didesoxyglycosides d'epipodophyllotoxine, leur procede de preparation, leur utilisation comme medicament et leur utilisation destinee aux traitements anticancereux

Info

Publication number
FR2739857B1
FR2739857B1 FR9511978A FR9511978A FR2739857B1 FR 2739857 B1 FR2739857 B1 FR 2739857B1 FR 9511978 A FR9511978 A FR 9511978A FR 9511978 A FR9511978 A FR 9511978A FR 2739857 B1 FR2739857 B1 FR 2739857B1
Authority
FR
France
Prior art keywords
didesoxyglycoside
epipodophyllotoxin
medicament
novel
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9511978A
Other languages
English (en)
Other versions
FR2739857A1 (fr
Inventor
Claude Monneret
Laurent Daley
Yves Guminski
Thierry Imbert
Bridget Hill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9511978A priority Critical patent/FR2739857B1/fr
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Priority to CA002234484A priority patent/CA2234484A1/fr
Priority to PCT/FR1996/001588 priority patent/WO1997013776A2/fr
Priority to AU73040/96A priority patent/AU7304096A/en
Priority to KR1019980702647A priority patent/KR19990064166A/ko
Priority to NZ320323A priority patent/NZ320323A/xx
Priority to JP9514777A priority patent/JP2000505053A/ja
Priority to EP96934895A priority patent/EP0873347A2/fr
Priority to CN96198199A priority patent/CN1202173A/zh
Priority to BR9610851A priority patent/BR9610851A/pt
Publication of FR2739857A1 publication Critical patent/FR2739857A1/fr
Application granted granted Critical
Publication of FR2739857B1 publication Critical patent/FR2739857B1/fr
Priority to MXPA/A/1998/002933A priority patent/MXPA98002933A/xx
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FR9511978A 1995-10-12 1995-10-12 Nouveaux derives amines de 2",3"-didesoxyglycosides d'epipodophyllotoxine, leur procede de preparation, leur utilisation comme medicament et leur utilisation destinee aux traitements anticancereux Expired - Fee Related FR2739857B1 (fr)

Priority Applications (11)

Application Number Priority Date Filing Date Title
FR9511978A FR2739857B1 (fr) 1995-10-12 1995-10-12 Nouveaux derives amines de 2",3"-didesoxyglycosides d'epipodophyllotoxine, leur procede de preparation, leur utilisation comme medicament et leur utilisation destinee aux traitements anticancereux
CN96198199A CN1202173A (zh) 1995-10-12 1996-10-11 表鬼臼毒素2″,3″二脱氧糖苷的新型胺衍生物,其制备方法其作为药物的应用及其抗癌治疗的应用
AU73040/96A AU7304096A (en) 1995-10-12 1996-10-11 Novel amine derivatives of epipodophyllotoxin 2", 3"-dideoxyglycosides, preparation method therefor and use thereof as a drug and for treating cancer
KR1019980702647A KR19990064166A (ko) 1995-10-12 1996-10-11 에피포도필로톡신 2",3"-디데옥시글리코시드의 신규한 아민 유도체, 그것의 제조방법, 및 약물로서 사용하는 방법 및 암 치료에 사용하는 방법<
NZ320323A NZ320323A (en) 1995-10-12 1996-10-11 Amine derivatives of epipodophyllotoxin 2", 3"- dideoxyglycosides, preparation and use thereof as a drug and for treating cancer
JP9514777A JP2000505053A (ja) 1995-10-12 1996-10-11 エピポドフイロトキシン２”，３”−ジデオキシグリコシドの新規アミン誘導体、その調製方法、ならびに薬剤用および抗がん治療用としてのその使用
CA002234484A CA2234484A1 (fr) 1995-10-12 1996-10-11 Nouveaux derives amines de 2", 3" didesoxyglycosides d'epipodophyllotoxine, leur procede de preparation, leur utilisation comme medicament et leur utilisation destinee aux traitements anticancereux
PCT/FR1996/001588 WO1997013776A2 (fr) 1995-10-12 1996-10-11 Nouveaux derives amines de 2', 3' didesoxyglycosides d'epipodophyllotoxine, leur procede de preparation, leur utilisation comme medicament et leur utilisation destinee aux traitements anticancereux
BR9610851A BR9610851A (pt) 1995-10-12 1996-10-11 Composto processo de preparação de composto medicamento composição farmacêuticas e utilização do composto
EP96934895A EP0873347A2 (fr) 1995-10-12 1996-10-11 Nouveaux derives amines de 2", 3" didesoxyglycosides d'epipodophyllotoxine, leur procede de preparation, leur utilisation comme medicament et leur utilisation destinee aux traitements anticancereux
MXPA/A/1998/002933A MXPA98002933A (en) 1995-10-12 1998-04-13 Novedous derivatives of amina of 2", 3" -didesoxiglicosidos of epipodofilotoxina, method of preparation of the same and use of them with a drug and for treatments antican

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9511978A FR2739857B1 (fr) 1995-10-12 1995-10-12 Nouveaux derives amines de 2",3"-didesoxyglycosides d'epipodophyllotoxine, leur procede de preparation, leur utilisation comme medicament et leur utilisation destinee aux traitements anticancereux

Publications (2)

Publication Number Publication Date
FR2739857A1 FR2739857A1 (fr) 1997-04-18
FR2739857B1 true FR2739857B1 (fr) 1998-01-02

Family

ID=9483465

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9511978A Expired - Fee Related FR2739857B1 (fr) 1995-10-12 1995-10-12 Nouveaux derives amines de 2",3"-didesoxyglycosides d'epipodophyllotoxine, leur procede de preparation, leur utilisation comme medicament et leur utilisation destinee aux traitements anticancereux

Country Status (10)

Country Link
EP (1) EP0873347A2 (fr)
JP (1) JP2000505053A (fr)
KR (1) KR19990064166A (fr)
CN (1) CN1202173A (fr)
AU (1) AU7304096A (fr)
BR (1) BR9610851A (fr)
CA (1) CA2234484A1 (fr)
FR (1) FR2739857B1 (fr)
NZ (1) NZ320323A (fr)
WO (1) WO1997013776A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2800374B1 (fr) * 1999-10-28 2002-06-28 Adir Nouveaux derives de 9-(3,5-dimethoxyphenyl)-5,8,8a,9- tetrahydrofuro[3',4':6,7]naphto[2,3-d] [1,3]dioxol-6(5ah)- one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
TWI307341B (en) * 2002-10-11 2009-03-11 Plantaceutica Inc Anticancer compounds
FR2859208B1 (fr) 2003-09-02 2006-01-21 Servier Lab Nouveaux derives de 9-amino-podophyllotoxine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN102115483B (zh) * 2009-12-30 2014-12-17 苏州天人合生物技术有限公司 卤代双去氧糖衍生物及其制备方法与应用
CN109369667B (zh) * 2018-12-05 2021-04-13 南通大学 2，3，6-三脱氧糖基去甲表鬼臼毒素化合物及其制备方法和用途
CN110294764B (zh) * 2019-07-15 2021-04-20 中国科学院兰州化学物理研究所 一种偶氮键连接的鬼臼毒素衍生物及其制备方法
CN112079879B (zh) * 2020-08-21 2022-01-14 华润双鹤药业股份有限公司沧州分公司 一种替尼泊苷中间体的合成新方法及替尼泊苷的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6032799A (ja) * 1983-07-29 1985-02-19 Microbial Chem Res Found 新規４′−デメチル−４−エピポドフィロトキシン誘導体
US5066645A (en) * 1989-09-01 1991-11-19 Bristol-Myers Company Epipodophyllotoxin altroside derivatives

Also Published As

Publication number Publication date
WO1997013776A2 (fr) 1997-04-17
FR2739857A1 (fr) 1997-04-18
JP2000505053A (ja) 2000-04-25
MX9802933A (es) 1998-11-29
EP0873347A2 (fr) 1998-10-28
AU7304096A (en) 1997-04-30
BR9610851A (pt) 1999-07-13
KR19990064166A (ko) 1999-07-26
CA2234484A1 (fr) 1997-04-17
NZ320323A (en) 1999-07-29
WO1997013776A3 (fr) 1997-06-05
CN1202173A (zh) 1998-12-16

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