AU714886B2 - Powdered medication inhaler - Google Patents

Powdered medication inhaler Download PDF

Info

Publication number
AU714886B2
AU714886B2 AU18508/97A AU1850897A AU714886B2 AU 714886 B2 AU714886 B2 AU 714886B2 AU 18508/97 A AU18508/97 A AU 18508/97A AU 1850897 A AU1850897 A AU 1850897A AU 714886 B2 AU714886 B2 AU 714886B2
Authority
AU
Australia
Prior art keywords
powder
counter ring
wall
pawl
powder inhaler
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU18508/97A
Other languages
English (en)
Other versions
AU1850897A (en
Inventor
Thomas J Ambrosio
Warren A. Benson Jr.
Kim C. Dao
David J Kenyon
Walter J. Kreiseder
Theodore J. Schonebaum
Allen J. Vogel
Louis B. Walker
Tsong-Toh Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of AU1850897A publication Critical patent/AU1850897A/en
Application granted granted Critical
Publication of AU714886B2 publication Critical patent/AU714886B2/en
Assigned to MERCK SHARP & DOHME CORP. reassignment MERCK SHARP & DOHME CORP. Request to Amend Deed and Register Assignors: SCHERING CORPORATION
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001Particle size control
    • A61M11/002Particle size control by flow deviation causing inertial separation of transported particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • A61M15/0025Mouthpieces therefor with caps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007Mechanical counters
    • A61M15/0071Mechanical counters having a display or indicator
    • A61M15/0073Mechanical counters having a display or indicator on a ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/0081Locking means
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06MCOUNTING MECHANISMS; COUNTING OF OBJECTS NOT OTHERWISE PROVIDED FOR
    • G06M1/00Design features of general application
    • G06M1/14Design features of general application for transferring a condition from one stage to a higher stage
    • G06M1/16Design features of general application for transferring a condition from one stage to a higher stage self-operating, e.g. by Geneva mechanism
    • G06M1/163Design features of general application for transferring a condition from one stage to a higher stage self-operating, e.g. by Geneva mechanism with drums
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/008Electronic counters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Nozzles (AREA)
  • Coating Apparatus (AREA)
  • Filling Or Emptying Of Bunkers, Hoppers, And Tanks (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Closures For Containers (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
AU18508/97A 1996-02-21 1997-02-13 Powdered medication inhaler Expired AU714886B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60454996A 1996-02-21 1996-02-21
US08/604549 1996-02-21
PCT/US1997/001562 WO1997030743A2 (en) 1996-02-21 1997-02-13 Powdered medication inhaler

Publications (2)

Publication Number Publication Date
AU1850897A AU1850897A (en) 1997-09-10
AU714886B2 true AU714886B2 (en) 2000-01-13

Family

ID=24420048

Family Applications (1)

Application Number Title Priority Date Filing Date
AU18508/97A Expired AU714886B2 (en) 1996-02-21 1997-02-13 Powdered medication inhaler

Country Status (28)

Country Link
US (1) US6240918B1 (enExample)
EP (1) EP0883415B1 (enExample)
JP (2) JP3830972B2 (enExample)
KR (1) KR100453610B1 (enExample)
CN (1) CN1159076C (enExample)
AR (1) AR005888A1 (enExample)
AT (1) ATE216903T1 (enExample)
AU (1) AU714886B2 (enExample)
BR (1) BR9707660A (enExample)
CA (1) CA2245799C (enExample)
CZ (1) CZ298885B6 (enExample)
DE (1) DE69712324T2 (enExample)
DK (1) DK0883415T3 (enExample)
ES (1) ES2172763T3 (enExample)
HU (1) HU221033B1 (enExample)
ID (1) ID19343A (enExample)
IL (1) IL120246A (enExample)
MY (1) MY115064A (enExample)
NO (1) NO316787B1 (enExample)
NZ (1) NZ331361A (enExample)
PL (1) PL185384B1 (enExample)
PT (1) PT883415E (enExample)
RU (1) RU2195965C2 (enExample)
SK (1) SK287878B6 (enExample)
TW (1) TW333459B (enExample)
UA (1) UA49878C2 (enExample)
WO (1) WO1997030743A2 (enExample)
ZA (1) ZA971324B (enExample)

Families Citing this family (141)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU219117B (hu) * 1994-09-16 2001-02-28 Laboratoire Glaxo Wellcome S.A. Inhalálóeszköz
US7131441B1 (en) 1995-12-07 2006-11-07 Skyepharma Ag Inhaler for multiple dosed administration of a pharmacological dry powder
ES2148812T3 (es) 1995-12-07 2000-10-16 Jago Res Ag Inhalador para la administracion de dosis multiples de un polvo seco farmacologico.
GB9626263D0 (en) * 1996-12-18 1997-02-05 Innovata Biomed Ltd Powder inhaler
SE9700938D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler II and a method of construction thereof
TW469832U (en) 1997-03-14 2001-12-21 Astra Ab Inhalation device
US7143764B1 (en) * 1998-03-13 2006-12-05 Astrazeneca Ab Inhalation device
DE29814647U1 (de) * 1998-08-14 1999-12-23 Josef Wischerath Gmbh & Co. Kg, 50259 Pulheim Inhalator mit einer Dosierzähleinrichtung
DE29908593U1 (de) 1999-05-14 1999-07-22 Jago Research AG, Hergiswil Mundstück für einen Inhalator zur Abgabe eines Medikaments
MXPA01012533A (es) * 1999-06-05 2003-10-14 Innovata Biomed Ltd Sistema de suministro.
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
GB9920839D0 (en) * 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
AU3400501A (en) * 2000-02-28 2001-09-12 Vectura Ltd Improvements in or relating to the delivery of oral drugs
US6626171B2 (en) * 2000-05-12 2003-09-30 Iep Pharmaceutical Devices Inc. Powder/liquid metering valve
GB2364649A (en) 2000-05-17 2002-02-06 Orion Corp Inhaler with Dose Counter
PE20020075A1 (es) 2000-06-23 2002-02-05 Norton Healthcare Ltd Dispositivo contador de dosis para inhalador de medicamento
FR2811576B1 (fr) * 2000-07-13 2003-01-24 Henri Bocquee Disposits ou appareils d'administration de produits actifs pulverurents du type medicaments ou vaccins, par voie pulmonaire
US6595210B2 (en) * 2000-11-27 2003-07-22 Unisia Jecs Corporation Inhalator for administering powder composition
WO2002062317A2 (en) * 2001-02-06 2002-08-15 Innovata Biomed Limited Bimodal dry powder formulation for inhalation
SE518397C2 (sv) * 2001-04-05 2002-10-01 Microdrug Ag Förfarande och anordning för frigörande av pulver och inhalatoranordning för administrering av medicinskt pulver
US6766799B2 (en) * 2001-04-16 2004-07-27 Advanced Inhalation Research, Inc. Inhalation device
GB0128148D0 (en) * 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
US6772756B2 (en) 2002-02-09 2004-08-10 Advanced Inhalation Revolutions Inc. Method and system for vaporization of a substance
GB0204829D0 (en) * 2002-03-01 2002-04-17 Glaxo Group Ltd A fluid dispensing device
ES2300568T3 (es) * 2002-03-20 2008-06-16 Mannkind Corporation Aparato de inhalacion.
DK1487523T3 (en) 2002-03-22 2017-08-28 Clinical Designs Ltd FIXING FOR A BOX
EP2497514B8 (de) * 2002-09-16 2015-12-16 Sanofi SA Inhalator für pulverförmige, insbesondere medizinische Substanzen
GB0222023D0 (en) * 2002-09-21 2002-10-30 Aventis Pharma Ltd Inhaler
US7322352B2 (en) 2002-09-21 2008-01-29 Aventis Pharma Limited Inhaler
AU2003272935C1 (en) * 2002-10-11 2009-06-25 Otsuka Pharmaceutical Co., Ltd. Powder inhalation device
US20040187869A1 (en) 2003-01-17 2004-09-30 Schering Corporation Training device for medicament inhalers
GB0304000D0 (en) 2003-02-21 2003-03-26 Clinical Designs Ltd Dispenser
US20040177848A1 (en) * 2003-03-12 2004-09-16 Alley Kenneth A. Multi-compartment inhaler
GB0313604D0 (en) * 2003-06-12 2003-07-16 Britannia Pharmaceuticals Ltd Delivery device for powdered medicament
GB0327112D0 (en) 2003-11-21 2003-12-24 Clincial Designs Ltd Dispenser and reservoir
GB0328859D0 (en) 2003-12-12 2004-01-14 Clinical Designs Ltd Dispenser and counter
GB0403394D0 (en) * 2004-02-16 2004-03-17 Glaxo Group Ltd Counter for use with a medicament dispenser
EP1730676B1 (en) * 2004-02-16 2013-08-28 Glaxo Group Limited Counter for use with a medicament dispenser
ES2936138T3 (es) * 2004-03-10 2023-03-14 Glaxo Group Ltd Un dispositivo dispensador
CA2561666C (en) * 2004-03-31 2010-12-07 The Sherwin-Williams Company Paint container and lid assembly
EP1744800B1 (en) * 2004-04-21 2016-06-22 Innovata Biomed Limited Inhaler
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
GB0410712D0 (en) * 2004-05-13 2004-06-16 Novartis Ag Organic compounds
PL1616592T3 (pl) * 2004-07-16 2011-03-31 Astrazeneca Ab Inhalator do podawania sproszkowanych środków farmaceutycznych i proszkowa kaseta do użycia z tym inhalatorem
CN101039714B (zh) * 2004-08-12 2012-07-11 帝人制药株式会社 供给装置的计数器机构及具备计数器机构的供给装置
WO2006023849A2 (en) 2004-08-20 2006-03-02 Mannkind Corporation Catalysis of diketopiperazine synthesis
KR20150039211A (ko) 2004-08-23 2015-04-09 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
GB0425518D0 (en) 2004-11-19 2004-12-22 Clinical Designs Ltd Substance source
GB0428204D0 (en) 2004-12-23 2005-01-26 Clinical Designs Ltd Medicament container
TWI372749B (en) 2005-03-10 2012-09-21 Theravance Inc Crystalline forms of a biphenyl compound
FR2883400B1 (fr) 2005-03-16 2007-06-15 Valois Sas Dispositif d'indication de doses pour distribuer des produits fluides ou pulverulents
EP2484382A1 (en) 2005-03-30 2012-08-08 Schering Corporation Medicament comprising a phosphodiesterase IV inhibitor in an inhalable form
USD550835S1 (en) * 2005-07-22 2007-09-11 Omron Healthcare Co., Ltd. Atomizer for inhaler
GB0518400D0 (en) * 2005-09-09 2005-10-19 Clinical Designs Ltd Dispenser
WO2007033372A2 (en) 2005-09-14 2007-03-22 Mannkind Corporation Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
GB0519151D0 (en) 2005-09-20 2005-10-26 Aventis Pharma Ltd Inhaler
KR100709270B1 (ko) 2005-09-28 2007-04-19 문찬식 휴대가 가능한 액상향료 흡입 장치
US20070099883A1 (en) * 2005-10-07 2007-05-03 Cheryl Lynn Calis Anhydrous mometasone furoate formulation
MX339072B (es) 2005-11-21 2016-05-09 Mannkind Corp Aparato y metodos para suministrar y detectar polvo.
AU2007216966C1 (en) 2006-02-22 2014-03-20 Mannkind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
GB0605150D0 (en) * 2006-03-14 2006-04-26 Glaxo Group Ltd Counter For Use With A Medicament Dispenser
RU2456026C2 (ru) * 2006-06-16 2012-07-20 Сипла Лимитед Усовершенствованный ингалятор для сухого порошкообразного препарата
DE102006045788A1 (de) * 2006-09-26 2008-03-27 Alfred Von Schuckmann Spender für pulverförmige Massen
JP5099722B2 (ja) * 2006-12-11 2012-12-19 アプター フランス エスアーエス 流体ディスペンサ装置
WO2008091355A2 (en) * 2007-01-24 2008-07-31 Breathe Pharmaceuticals, Inc. Drug transfer device
AP2007000277S (en) * 2007-03-28 2007-10-04 Xerxes Rao Cartridge for multidose inhaler
GB2448183A (en) 2007-04-05 2008-10-08 Optinose As Nasal powder delivery device
GB0713876D0 (en) * 2007-07-18 2007-08-29 3M Innovative Properties Co Manufacture of components for medicinal dispensers
US8367662B2 (en) 2007-10-17 2013-02-05 Novartis Ag Organic compounds
CN201337727Y (zh) * 2007-12-28 2009-11-04 国家纳米技术与工程研究院 一种肺部给药的干粉吸入器装置
CA2711637A1 (en) 2008-01-11 2009-07-16 Novartis Ag Pyrimidines as kinase inhibitors
WO2009093969A1 (en) * 2008-01-23 2009-07-30 Astrazeneca Ab A medicament-containing dispenser provided with a display for presenting indicia to a user
EP2285440B2 (en) 2008-05-02 2018-10-24 Boehringer Ingelheim International GmbH Inhaler
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
SG10201507036TA (en) 2008-06-13 2015-10-29 Mannkind Corp A dry powder inhaler and system for drug delivery
US9364619B2 (en) 2008-06-20 2016-06-14 Mannkind Corporation Interactive apparatus and method for real-time profiling of inhalation efforts
PL2334560T3 (pl) * 2008-08-05 2014-04-30 Mannkind Corp Moduły dozownika proszku i zespoły dozownika proszku
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
GB0904059D0 (en) 2009-03-10 2009-04-22 Euro Celtique Sa Counter
GB0904040D0 (en) 2009-03-10 2009-04-22 Euro Celtique Sa Counter
EP2676695A3 (en) 2009-03-11 2017-03-01 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
MX344153B (es) 2009-04-09 2016-12-07 Novartis Ag Proceso para la preparación de sales de pirrolidinio.
SG176738A1 (en) 2009-06-12 2012-01-30 Mannkind Corp Diketopiperazine microparticles with defined specific surface areas
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
AU2010319696B2 (en) * 2009-11-13 2014-07-31 Merck Sharp & Dohme Corp. Drug products and dry powder inhalers with multiple reservoirs
USD665073S1 (en) * 2010-02-26 2012-08-07 Omron Healthcare Co., Ltd. Atomizer for inhaler
EP2582421A1 (en) 2010-06-21 2013-04-24 MannKind Corporation Dry powder drug delivery system and methods
US8372845B2 (en) 2010-09-17 2013-02-12 Novartis Ag Pyrazine derivatives as enac blockers
JOP20120023B1 (ar) 2011-02-04 2022-03-14 Novartis Ag صياغات مساحيق جافة من جسيمات تحتوي على واحد أو اثنين من المواد الفعالة لعلاج امراض ممرات الهواء الانسدادية او الالتهابية
CA3078334C (en) 2011-04-01 2022-08-09 Mannkind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
UY34305A (es) 2011-09-01 2013-04-30 Novartis Ag Derivados de heterociclos bicíclicos para el tratamiento de la hipertensión arterial pulmonar
US9202164B2 (en) 2011-09-26 2015-12-01 Trudell Medical International Dose counter and medication delivery device
AU2012328885B2 (en) 2011-10-24 2017-08-31 Mannkind Corporation Methods and compositions for treating pain
GB201118842D0 (en) 2011-11-01 2011-12-14 Euro Celtique Sa Dispenser cap arrangement
JP6058698B2 (ja) 2012-01-13 2017-01-11 ノバルティス アーゲー Ip受容体アゴニストの塩
US8809340B2 (en) 2012-03-19 2014-08-19 Novartis Ag Crystalline form
CN104245150B (zh) * 2012-04-26 2017-12-15 皇家飞利浦有限公司 雾化器和制造雾化器的方法
EP2872205B1 (en) 2012-07-12 2017-02-08 MannKind Corporation Dry powder drug delivery systems
KR20150030256A (ko) * 2012-07-31 2015-03-19 사노피 에스에이 약물 전달 기구를 위한 배열
CN103656811B (zh) * 2012-09-19 2015-06-17 上海理工大学 粉剂定量给药装置
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
USD727492S1 (en) * 2012-12-06 2015-04-21 Koninklijke Philips N.V. Disposable airway adapter for respiratory gas monitoring
KR20150095888A (ko) 2012-12-19 2015-08-21 노파르티스 아게 오토탁신 억제제
US9073921B2 (en) 2013-03-01 2015-07-07 Novartis Ag Salt forms of bicyclic heterocyclic derivatives
US9452139B2 (en) 2013-03-14 2016-09-27 Novartis Ag Respirable agglomerates of porous carrier particles and micronized drug
JP6232079B2 (ja) 2013-03-14 2017-11-15 ノバルティス アーゲー スプレーブレンディングによるスプレー乾燥製剤の脱アモルファス化
KR102246914B1 (ko) 2013-03-15 2021-04-30 맨카인드 코포레이션 미세결정성 디케토피페라진 조성물 및 방법
EP3022202B1 (en) 2013-07-18 2019-05-15 Novartis AG Autotaxin inhibitors comprising a heteroaromatic ring-benzyl-amide-cycle core
US9925144B2 (en) 2013-07-18 2018-03-27 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
WO2015008229A1 (en) 2013-07-18 2015-01-22 Novartis Ag Autotaxin inhibitors
US11446127B2 (en) 2013-08-05 2022-09-20 Mannkind Corporation Insufflation apparatus and methods
GB201319265D0 (en) * 2013-10-31 2013-12-18 Norton Waterford Ltd Medicament inhaler
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
AU2014391608A1 (en) 2014-04-24 2016-10-27 Novartis Ag Amino pyrazine derivatives as phosphatidylinositol 3-kinase inhibitors
WO2015162558A1 (en) 2014-04-24 2015-10-29 Novartis Ag Autotaxin inhibitors
PT3134396T (pt) 2014-04-24 2019-12-16 Novartis Ag Derivados de amino piridina como inibidores da fosfatidilinositol 3-quinase
PL3134395T3 (pl) 2014-04-24 2018-07-31 Novartis Ag Pochodne pirazyny jako inhibitory 3-kinazy fosfatydyloinozytolu
WO2015173656A1 (en) 2014-05-14 2015-11-19 Novartis Ag Carboxamide derivatives
WO2015173659A2 (en) 2014-05-14 2015-11-19 Novartis Ag Carboxamide derivatives
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
TW201636068A (zh) * 2015-01-13 2016-10-16 賽諾菲股份有限公司 藥物輸送裝置之組件
EP3294389B1 (en) * 2015-05-08 2020-07-22 Iconovo AB Dry powder inhaler comprising a locking mechanism
WO2016180753A1 (en) * 2015-05-08 2016-11-17 Iconovo Ab Dry powder inhaler
CA2997352A1 (en) * 2015-09-02 2017-03-09 Mylan Inc. Medication packaging and dose regimen system
EP3393562B1 (en) 2015-12-21 2021-08-11 Kindeva Drug Delivery L.P. Medicinal inhalers
US11071837B2 (en) 2015-12-21 2021-07-27 Kindeva Drug Delivery L.P. Dose release firing systems and medicinal inhalers comprising same
WO2017112451A1 (en) 2015-12-21 2017-06-29 3M Innovative Properties Company Auto-reset dose release firing systems, medicinal inhalers comprising same, and methods of using same
AU2017361383B2 (en) 2016-11-21 2023-10-05 Ecolab Usa Inc. Material supply system with a valve assembly and a base assembly provided with an actuator
AU2017361381B2 (en) 2016-11-21 2023-09-28 Ecolab Usa Inc. Material supply system with valve assembly with improved sealing capabilities
CA3083591A1 (en) 2017-12-04 2019-06-13 Ecolab Usa Inc. Material wetting system with shroud assembly
MX2020005768A (es) 2017-12-04 2020-08-20 Ecolab Usa Inc Sistema de tolva de material en polvo con carga desplazada.
WO2019122361A1 (en) 2017-12-22 2019-06-27 Dr. August Wolff Gmbh & Co. Kg Arzneimittel Asimadoline for use in treating pulmonary diseases, vascular diseases, and sepsis
US11206864B2 (en) * 2018-03-26 2021-12-28 Rai Strategic Holdings, Inc. Aerosol delivery device providing flavor control
CN108741239B (zh) * 2018-09-17 2021-01-12 杭州清大科瑞生物科技有限公司 一种电子烟式烟弹可替换的干细胞吸入装置
FR3098420B1 (fr) * 2019-07-10 2021-07-09 Aptar France Sas Dispositif de distribution nasale de poudre
WO2021152119A1 (en) 2020-01-31 2021-08-05 Advita Lifescience Gmbh Human anti-inflammatory peptides for the inhalatory treatment of inflammatory pulmonary diseases
CN113262365B (zh) * 2021-05-19 2023-06-23 西安交通大学医学院第二附属医院 一种急诊科雾化装置
CN114432546B (zh) * 2021-12-31 2024-04-16 上海成煜医疗科技有限公司 吸入式给药器的计数装置
US20230372646A1 (en) * 2022-05-19 2023-11-23 Willie Tsang Inhaling device

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4907583A (en) * 1986-03-07 1990-03-13 Aktiebolaget Draco Device in powder inhalators
WO1994014492A2 (en) * 1992-12-18 1994-07-07 Schering Corporation Inhaler for powdered medications

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2432641A (en) * 1944-06-20 1947-12-16 Wilsons Sons Inc William M Dispensing nozzle or faucet
US2456451A (en) * 1946-05-31 1948-12-14 Scovill Manufacturing Co Inhaler
US2604094A (en) 1949-06-25 1952-07-22 Schenley Ind Inc Inhaler
US3024787A (en) * 1957-03-20 1962-03-13 Herbert M Birch Means for administering pressurized medicaments, gases, combination thereof and liquids into body cavities
US3587573A (en) * 1969-06-20 1971-06-28 John Gene Flack Inhalation device with rupturable microscopic capsules
GB1283205A (en) * 1969-09-30 1972-07-26 Griffiths Fuel Injection Dev L Improvements relating to fuel injection apparatus for internal combustion engines
SE448277B (sv) 1985-04-12 1987-02-09 Draco Ab Indikeringsanordning vid en doseringsanordning for lekemedel
DK479189D0 (da) 1989-01-06 1989-09-28 Hans Gernot Schenk Inhalator
SE466684B (sv) * 1989-03-07 1992-03-23 Draco Ab Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator
IT1237118B (it) 1989-10-27 1993-05-18 Miat Spa Inalatore multidose per farmaci in polvere.
US5113855A (en) * 1990-02-14 1992-05-19 Newhouse Michael T Powder inhaler
DE4004904A1 (de) * 1990-02-16 1990-09-13 Gerhard Brendel Trommel-applikator
IT1240750B (it) 1990-04-12 1993-12-17 Chiesi Farma Spa Dispositivo per la somministrazione di sostanze medicamentose in polvere
US5429122A (en) * 1990-09-26 1995-07-04 Zanen; Pieter Inhaler devices provided with a reservoir for several doses of medium for inhaling, transporting device, whirl chamber
GB9027234D0 (en) * 1990-12-15 1991-02-06 Harris Pharma Ltd An inhalation device
US5129582A (en) * 1990-12-26 1992-07-14 General Turbine Systems, Inc. Turbine injector device and method
DE4142238A1 (de) * 1991-12-20 1993-06-24 Boehringer Ingelheim Kg Pulverinhalator mit pulvertraeger aus regelmaessigen mikrostrukturen
SE9201411D0 (sv) 1992-05-05 1992-05-05 Astra Ab Dosage inhalator with indicating/interupting means
US5394868A (en) * 1992-06-25 1995-03-07 Schering Corporation Inhalation device for powdered medicaments
US5785049A (en) * 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
SE9203570D0 (sv) 1992-11-27 1992-11-27 Astra Ab Inhaler for multiple use
JP3132830B2 (ja) * 1993-05-12 2001-02-05 帝人株式会社 粉末状薬剤マルチドース施薬装置
US5415162A (en) * 1994-01-18 1995-05-16 Glaxo Inc. Multi-dose dry powder inhalation device

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4907583A (en) * 1986-03-07 1990-03-13 Aktiebolaget Draco Device in powder inhalators
WO1994014492A2 (en) * 1992-12-18 1994-07-07 Schering Corporation Inhaler for powdered medications

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