AU6928794A - Carbazole derivatives with 17,20-lyase-inhibiting activity - Google Patents
Carbazole derivatives with 17,20-lyase-inhibiting activityInfo
- Publication number
- AU6928794A AU6928794A AU69287/94A AU6928794A AU6928794A AU 6928794 A AU6928794 A AU 6928794A AU 69287/94 A AU69287/94 A AU 69287/94A AU 6928794 A AU6928794 A AU 6928794A AU 6928794 A AU6928794 A AU 6928794A
- Authority
- AU
- Australia
- Prior art keywords
- compound
- formula
- group
- carbazole
- fluoro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939310635A GB9310635D0 (en) | 1993-05-21 | 1993-05-21 | Chemical compounds |
| GB9310635 | 1993-05-21 | ||
| PCT/EP1994/001613 WO1994027989A1 (en) | 1993-05-21 | 1994-05-19 | Carbazole derivatives with 17,20-lyase-inhibiting activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU6928794A true AU6928794A (en) | 1994-12-20 |
Family
ID=10736007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU69287/94A Abandoned AU6928794A (en) | 1993-05-21 | 1994-05-19 | Carbazole derivatives with 17,20-lyase-inhibiting activity |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0699196A1 (fi) |
| JP (1) | JPH08510455A (fi) |
| CN (1) | CN1126473A (fi) |
| AU (1) | AU6928794A (fi) |
| BG (1) | BG100154A (fi) |
| CA (1) | CA2162921A1 (fi) |
| CZ (1) | CZ305195A3 (fi) |
| FI (1) | FI955587A0 (fi) |
| GB (1) | GB9310635D0 (fi) |
| HU (1) | HUT73790A (fi) |
| IL (1) | IL109703A0 (fi) |
| NO (1) | NO954681D0 (fi) |
| OA (1) | OA10195A (fi) |
| PE (1) | PE31195A1 (fi) |
| PL (1) | PL311702A1 (fi) |
| SK (1) | SK142495A3 (fi) |
| TW (1) | TW279866B (fi) |
| WO (1) | WO1994027989A1 (fi) |
| ZA (1) | ZA943494B (fi) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0721943A4 (en) * | 1993-09-30 | 1996-09-04 | Yamanouchi Pharma Co Ltd | AZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME |
| AU3846395A (en) * | 1994-11-07 | 1996-05-31 | Janssen Pharmaceutica N.V. | Compositions comprising carbazoles and cyclodextrins |
| HUP9801158A3 (en) * | 1995-03-01 | 1999-11-29 | Yamanouchi Pharma Co Ltd | Imidazole derivatives and medicinal composition thereof |
| DE69810760T2 (de) * | 1997-02-21 | 2003-11-20 | Takeda Chemical Industries Ltd | Verbindungen mit kondensierten ringen, verfahren zu ihrer herstellung und ihre anwendung |
| NZ526387A (en) | 2000-11-17 | 2004-02-27 | Takeda Chemical Industries Ltd | Imidazole derivatives having a steroid C17,20-lyase- inhibitory activity, their production process and use thereof |
| CA2429437A1 (en) | 2000-11-20 | 2002-05-23 | Takeda Chemical Industries, Ltd. | Imidazole derivatives, process for their preparation and their use |
| AU2002221080A1 (en) | 2000-12-08 | 2002-06-18 | Masami Kusaka | Substituted thiazole derivatives bearing 3-pyridyl groups, process for preparingthe same and use thereof |
| JP5204650B2 (ja) | 2005-06-24 | 2013-06-05 | イーライ リリー アンド カンパニー | アンドロゲン受容体調節物質として有用なテトラヒドロカルバゾール誘導体 |
| GB0525323D0 (en) | 2005-12-13 | 2006-01-18 | Sterix Ltd | Compound |
| US8093279B2 (en) | 2005-12-13 | 2012-01-10 | Gillian Reed, legal representative | Compound |
| CN100586932C (zh) * | 2007-01-26 | 2010-02-03 | 中国医学科学院医药生物技术研究所 | 抗肿瘤化合物及其制备方法 |
| EA021011B1 (ru) | 2009-06-26 | 2015-03-31 | Новартис Аг | 1,3-ДИЗАМЕЩЕННЫЕ ПРОИЗВОДНЫЕ ИМИДАЗОЛИДИН-2-ОНА В КАЧЕСТВЕ ИНГИБИТОРОВ Cyp 17 |
| EP2531029B1 (en) | 2010-02-04 | 2016-10-19 | Radius Health, Inc. | Selective androgen receptor modulators |
| PT2568806T (pt) | 2010-05-12 | 2016-08-05 | Radius Health Inc | Regimes terapêuticos |
| KR101823275B1 (ko) | 2010-08-04 | 2018-03-08 | 펠피큐어 파마슈티걸즈 아이엔씨 | 전립선 암종의 치료를 위한 병용 요법 |
| EP2627648A1 (en) | 2010-09-16 | 2013-08-21 | Novartis AG | 17aHYDROXYLASE/C17,20-LYASE INHIBITORS |
| JP5965909B2 (ja) | 2010-09-28 | 2016-08-10 | ラジウス ヘルス，インコーポレイテッド | 選択的アンドロゲン受容体モジュレーター |
| KR20140025492A (ko) | 2011-04-28 | 2014-03-04 | 노파르티스 아게 | 17α-히드록실라제/C17,20-리아제 억제제 |
| US9492460B2 (en) * | 2013-02-27 | 2016-11-15 | Bristol-Myers Squibb Company | Carbazole compounds useful as bromodomain inhibitors |
| WO2014158875A1 (en) | 2013-03-14 | 2014-10-02 | Pellficure Pharmaceuticals Inc. | Novel therapy for prostate carcinoma |
| US9421264B2 (en) | 2014-03-28 | 2016-08-23 | Duke University | Method of treating cancer using selective estrogen receptor modulators |
| DK3122426T3 (da) | 2014-03-28 | 2023-04-03 | Univ Duke | Behandling af brystcancer ved anvendelse af selektive østrogenreceptormodulatorer |
| CA2960750A1 (en) | 2014-09-12 | 2016-03-17 | Pellficure Pharmaceuticals, Inc. | Compositions and methods for treatment of prostate carcinoma |
| KR102397890B1 (ko) | 2016-06-22 | 2022-05-12 | 일립시스 파마 리미티드 | Ar+ 유방암 치료 방법 |
| EP3528799A1 (en) | 2016-10-24 | 2019-08-28 | Pellficure Pharmaceuticals, Inc. | Pharmaceutical compositions of 5-hydroxy-2-methylnaphthalene-1, 4-dione |
| EP3565542B1 (en) | 2017-01-05 | 2024-04-10 | Radius Pharmaceuticals, Inc. | Polymorphic forms of rad1901-2hcl |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CS229934B2 (en) * | 1981-07-07 | 1984-07-16 | Pfizer | Production method subst.indolylacryte acid derivative |
| GB8518743D0 (en) * | 1985-07-24 | 1985-08-29 | Glaxo Group Ltd | Heterocyclic compounds |
-
1993
- 1993-05-21 GB GB939310635A patent/GB9310635D0/en active Pending
-
1994
- 1994-05-02 ZA ZA943494A patent/ZA943494B/xx unknown
- 1994-05-17 TW TW083104441A patent/TW279866B/zh active
- 1994-05-19 PL PL94311702A patent/PL311702A1/xx unknown
- 1994-05-19 SK SK1424-95A patent/SK142495A3/sk unknown
- 1994-05-19 CN CN94192683A patent/CN1126473A/zh active Pending
- 1994-05-19 HU HU9503321A patent/HUT73790A/hu unknown
- 1994-05-19 CA CA002162921A patent/CA2162921A1/en not_active Abandoned
- 1994-05-19 CZ CZ953051A patent/CZ305195A3/cs unknown
- 1994-05-19 AU AU69287/94A patent/AU6928794A/en not_active Abandoned
- 1994-05-19 EP EP94917647A patent/EP0699196A1/en not_active Withdrawn
- 1994-05-19 JP JP7500181A patent/JPH08510455A/ja active Pending
- 1994-05-19 WO PCT/EP1994/001613 patent/WO1994027989A1/en not_active Application Discontinuation
- 1994-05-20 IL IL10970394A patent/IL109703A0/xx unknown
- 1994-11-18 PE PE1994255110A patent/PE31195A1/es not_active Application Discontinuation
-
1995
- 1995-11-17 OA OA60742A patent/OA10195A/en unknown
- 1995-11-20 FI FI955587A patent/FI955587A0/fi not_active Application Discontinuation
- 1995-11-20 NO NO954681A patent/NO954681D0/no unknown
- 1995-11-21 BG BG100154A patent/BG100154A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CZ305195A3 (en) | 1996-06-12 |
| SK142495A3 (en) | 1996-06-05 |
| PE31195A1 (es) | 1995-10-18 |
| IL109703A0 (en) | 1994-08-26 |
| HUT73790A (en) | 1996-09-30 |
| HU9503321D0 (en) | 1996-01-29 |
| FI955587A (fi) | 1995-11-20 |
| GB9310635D0 (en) | 1993-07-07 |
| CA2162921A1 (en) | 1994-12-08 |
| NO954681L (no) | 1995-11-20 |
| BG100154A (en) | 1996-07-31 |
| OA10195A (en) | 1996-12-18 |
| EP0699196A1 (en) | 1996-03-06 |
| TW279866B (fi) | 1996-07-01 |
| FI955587A0 (fi) | 1995-11-20 |
| PL311702A1 (en) | 1996-03-04 |
| JPH08510455A (ja) | 1996-11-05 |
| NO954681D0 (no) | 1995-11-20 |
| CN1126473A (zh) | 1996-07-10 |
| WO1994027989A1 (en) | 1994-12-08 |
| ZA943494B (en) | 1995-01-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU6928794A (en) | Carbazole derivatives with 17,20-lyase-inhibiting activity | |
| SU1574178A3 (ru) | Способ получени производных 4-замещенного андростендиона, или их фармацевтически приемлемых солей | |
| ES2424395T3 (es) | Derivados de estratrieno y sus usos como inhibidores de la 17-beta-hidroxiesteroide-deshidrogenasa | |
| IE904146A1 (en) | Indole Derivatives | |
| IE57809B1 (en) | 1,2,3,9-tetrahydro-3-(imidazol-1-ylmethyl)-4h-carbazol-4 one derivatives | |
| EP0430709A2 (en) | Benzthiophen derivatives | |
| EP3064498A1 (en) | Pyrazolopyrimidone or pyrrolotriazone derivatives, method of preparing same, and pharmaceutical applications thereof | |
| WO2023069884A1 (en) | Kdm1a inhibitors for the treatment of disease | |
| US5578630A (en) | Heterocyclic compounds which inhibit aromatase | |
| CA2214744C (en) | 3-(bis-substituted phenylmethylene)oxindole derivatives | |
| KR910002228B1 (ko) | 스테로이도[3, 2-c] 피라졸 및 그의 제조방법 | |
| EP0240263B1 (en) | Indenopyrimidine derivatives | |
| ZA200210201B (en) | Benzofuran Derivatives. | |
| EP0574992A1 (en) | 5-(1,2,4-Triazol-1-ylmethyl)-3H-isobenzofuran-1-one derivatives, their preparation and use as aromatase inhibitors | |
| JP3252189B2 (ja) | ピラゾロ〔１，５−ａ〕ピリミジン誘導体 | |
| US5726196A (en) | Aromatase-inhibiting composition containing azole derivative | |
| EP1000060A1 (en) | Novel compounds | |
| KR102591329B1 (ko) | 셀레탈리십의 결정형 | |
| CN117940430A (zh) | 作为Wee-1抑制剂的1,2-二氢-3H-吡唑[3,4-d]嘧啶-3-酮化合物 | |
| WO1994011369A1 (en) | ANTIHYPERTENSIVE 5-[(IMIDAZO[4,5-b]PYRIDIN-3-YL)METHYL]BENZOFURAN DERIVATIVES | |
| JPS6256471A (ja) | 含窒素四環式化合物 | |
| SK286757B6 (sk) | 17-Metylénsteroidy, spôsob ich prípravy, farmaceutické kompozície, ktoré ich obsahujú, a ich použitie | |
| JPS63119467A (ja) | カルボスチリル誘導体 | |
| KR20160008306A (ko) | 구굴스테론 유도체, 그 제조방법 및 그를 포함하는 조성물 | |
| JPS6172763A (ja) | プレニルベンズイミダゾ−ル誘導体および抗潰瘍剤 |