AU6820998A - A method for extracting quantitative information relating to an influence on a cellular response - Google Patents

A method for extracting quantitative information relating to an influence on a cellular response

Info

Publication number
AU6820998A
AU6820998A AU68209/98A AU6820998A AU6820998A AU 6820998 A AU6820998 A AU 6820998A AU 68209/98 A AU68209/98 A AU 68209/98A AU 6820998 A AU6820998 A AU 6820998A AU 6820998 A AU6820998 A AU 6820998A
Authority
AU
Australia
Prior art keywords
component
influence
protein
protein kinase
luminophore
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU68209/98A
Other languages
English (en)
Inventor
Almholt Kasper
Sara Petersen Bjorn
Kurt Scudder
Ole Thastrup
Soren Tullin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BioImage AS
Original Assignee
BioImage AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8092994&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU6820998(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by BioImage AS filed Critical BioImage AS
Publication of AU6820998A publication Critical patent/AU6820998A/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5035—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on sub-cellular localization
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
    • G01N2333/43595—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205—Phosphotransferases in general
    • G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
AU68209/98A 1997-04-07 1998-04-07 A method for extracting quantitative information relating to an influence on a cellular response Abandoned AU6820998A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK392/97 1997-04-07
DK39297 1997-04-07
PCT/DK1998/000145 WO1998045704A2 (en) 1997-04-07 1998-04-07 A method for extracting quantitative information relating to an influence on a cellular response

Publications (1)

Publication Number Publication Date
AU6820998A true AU6820998A (en) 1998-10-30

Family

ID=8092994

Family Applications (1)

Application Number Title Priority Date Filing Date
AU68209/98A Abandoned AU6820998A (en) 1997-04-07 1998-04-07 A method for extracting quantitative information relating to an influence on a cellular response

Country Status (11)

Country Link
US (3) US6518021B1 (enExample)
EP (3) EP1435519B1 (enExample)
JP (1) JP2001522454A (enExample)
AT (3) ATE354089T1 (enExample)
AU (1) AU6820998A (enExample)
CA (1) CA2286293C (enExample)
DE (4) DE69837118T2 (enExample)
DK (2) DK1435519T3 (enExample)
ES (2) ES2191575T3 (enExample)
PT (2) PT986753E (enExample)
WO (1) WO1998045704A2 (enExample)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU226203B1 (en) 1996-01-26 2008-06-30 Virco B V B A Method for determining of the chemotherapy of patients who are hiv positive based on the phenotypic drug sensitivity of human hiv strains
US7062219B2 (en) 1997-01-31 2006-06-13 Odyssey Thera Inc. Protein fragment complementation assays for high-throughput and high-content screening
US6416959B1 (en) 1997-02-27 2002-07-09 Kenneth Giuliano System for cell-based screening
US6759206B1 (en) 1997-02-27 2004-07-06 Cellomics, Inc. System for cell-based screening
US7853411B2 (en) 1997-02-27 2010-12-14 Cellomics, Inc. System for cell-based screening
WO1998045704A2 (en) * 1997-04-07 1998-10-15 Bioimage A/S A method for extracting quantitative information relating to an influence on a cellular response
US7160687B1 (en) 1997-05-29 2007-01-09 Cellomics, Inc. Miniaturized cell array methods and apparatus for cell-based screening
US6235512B1 (en) * 1997-07-01 2001-05-22 Tularik Inc. IKK-α proteins, nucleic acids and methods
US20050221280A1 (en) 1998-02-02 2005-10-06 Odyssey Thera, Inc. Protein-protein interactions for pharmacological profiling
US6388788B1 (en) 1998-03-16 2002-05-14 Praelux, Inc. Method and apparatus for screening chemical compounds
US20030036855A1 (en) 1998-03-16 2003-02-20 Praelux Incorporated, A Corporation Of New Jersey Method and apparatus for screening chemical compounds
AU765703B2 (en) * 1998-03-27 2003-09-25 Bruce J. Bryan Luciferases, fluorescent proteins, nucleic acids encoding the luciferases and fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items
US6037133A (en) * 1998-04-17 2000-03-14 Clontech Laboratories, Inc. IκBEGFP constructs, cell lines and methods of use
US6844315B2 (en) * 1998-05-20 2005-01-18 Erasmus Universiteit Rotterdam Immunoregulator
US8680059B2 (en) * 1998-05-20 2014-03-25 Biotempt B.V. Oligopeptide acetate and formulations thereof
US20030220258A1 (en) 2001-12-21 2003-11-27 Robbert Benner Treatment of ischemic events
AU6189999A (en) * 1998-10-15 2000-05-08 Bioimage A/S Specific therapeutic interventions obtained by interference with redistribution and/or targetting
EP1121593A2 (en) * 1998-10-15 2001-08-08 BioImage A/S Method for extracting quantitative information relating to an influence on a cellular response
GB9901072D0 (en) * 1999-01-19 1999-03-10 Imp Cancer Res Tech Methods for detecting changes to a macromolecular component of a cell
JP3576491B2 (ja) * 1999-02-26 2004-10-13 セロミックス インコーポレイテッド 細胞ベースのスクリーニング用のシステム
DE19915310A1 (de) * 1999-04-03 2000-10-05 Bayer Ag Diffusionskontrollierende Sensorschicht
EP1048952B1 (en) * 1999-04-29 2003-03-26 Erasmus Universiteit Rotterdam Determining analyte mobility
WO2000070528A2 (en) * 1999-05-14 2000-11-23 Cytokinetics, Inc. Method and apparatus for predictive cellular bioinformatics
US6651008B1 (en) 1999-05-14 2003-11-18 Cytokinetics, Inc. Database system including computer code for predictive cellular bioinformatics
US6743576B1 (en) 1999-05-14 2004-06-01 Cytokinetics, Inc. Database system for predictive cellular bioinformatics
US7151847B2 (en) 2001-02-20 2006-12-19 Cytokinetics, Inc. Image analysis of the golgi complex
US20030228565A1 (en) * 2000-04-26 2003-12-11 Cytokinetics, Inc. Method and apparatus for predictive cellular bioinformatics
EP1055929A1 (en) * 1999-05-26 2000-11-29 Tibotec N.V. Means and methods for drug discovery and the phenotypic characterisation of cells
US6573059B1 (en) * 1999-06-04 2003-06-03 Rmf Dictagene S.A. Use of the regulatory subunit of the camp dependent protein kinase (PKA) from dictyostelium for camp measurements
EP1101113A4 (en) * 1999-06-09 2002-05-08 Ljl Biosystems Inc CELL SIGNALING TESTS
US6673554B1 (en) 1999-06-14 2004-01-06 Trellie Bioinformatics, Inc. Protein localization assays for toxicity and antidotes thereto
AU7131900A (en) * 1999-06-21 2001-01-09 Cellomics, Inc. A system for cell-based screening
US6121047A (en) * 1999-07-21 2000-09-19 Isis Pharmaceuticals Inc. Antisense modulation of SHP-1 expression
US6489151B1 (en) * 2000-03-27 2002-12-03 The Research Foundation Of State University Of New York Biologically active alternative form of the IKKα IκB kinase
EP1300418A1 (en) * 2001-10-04 2003-04-09 Erasmus Universiteit Rotterdam Gene regulation by oligopeptides
KR100414641B1 (ko) * 2000-04-07 2004-01-13 동부한농화학 주식회사 형질전환식물체의 생체분석방법 및 그를 이용한 시스템
EP1276897A2 (en) * 2000-04-17 2003-01-22 BioImage A/S Live cell procedures to identify compounds modulating intracellular distribution of phosphodiesterase (pde) enzymes
US20030162165A1 (en) * 2000-04-26 2003-08-28 Arkhammer Per O.G. Chemical signal enhancement of dynamic intensity-based intracellular protein-and fluorophore-based redistribution assays for drug-screening
US20020049544A1 (en) * 2000-06-23 2002-04-25 Cytokinetics, Inc. Image analysis for phenotyping sets of mutant cells
JP2004502434A (ja) 2000-07-04 2004-01-29 バイオイメージ　エイ／エス 細胞成分間の相互作用に関する量的情報の抽出方法
US7625951B2 (en) 2000-07-13 2009-12-01 University Of Kentucky Research Foundation Stimuli-responsive hydrogel microdomes integrated with genetically engineered proteins for high-throughput screening of pharmaceuticals
DE10037759A1 (de) * 2000-08-03 2002-07-04 Gruenenthal Gmbh Screeningverfahren
KR100414781B1 (ko) * 2000-11-24 2004-01-13 재단법인서울대학교산학협력재단 ＮＦ-κＢ 발현을 인간 피부세포에서 정량적으로 측정하기위한 안정한 분석시스템 및 그의 용도
US7218764B2 (en) 2000-12-04 2007-05-15 Cytokinetics, Inc. Ploidy classification method
US6956961B2 (en) 2001-02-20 2005-10-18 Cytokinetics, Inc. Extracting shape information contained in cell images
US7016787B2 (en) 2001-02-20 2006-03-21 Cytokinetics, Inc. Characterizing biological stimuli by response curves
US7033790B2 (en) 2001-04-03 2006-04-25 Curagen Corporation Proteins and nucleic acids encoding same
EP1499885B1 (en) 2001-08-01 2009-10-21 Cellomics, Inc. Novel fusion proteins and assays for molecular binding
AU2002358657A1 (en) * 2001-12-10 2003-06-23 Evotec Oai Ag Method for determining the influence of non-physiological compounds the derivatives and decomposition products thereof on organisms organs and cells
US7176303B2 (en) * 2003-11-06 2007-02-13 Isis Pharmaceuticals, Inc. Modulation of STAT5 expression
US20080318871A1 (en) * 2001-12-21 2008-12-25 Khan Nisar A Treatment of neurological disorders
US20030220257A1 (en) * 2001-12-21 2003-11-27 Robbert Benner Treatment of trauma
US20080242837A1 (en) * 2001-12-21 2008-10-02 Khan Nisar A Peptide compositions
US7560433B2 (en) 2001-12-21 2009-07-14 Biotempt B.V. Treatment of multiple sclerosis (MS)
US7786084B2 (en) * 2001-12-21 2010-08-31 Biotempt B.V. Treatment of burns
CA2413475C (en) 2002-04-25 2010-07-27 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Zap-70 expression as a marker for chronic lymphocytic leukemia/small lymphocytic lymphoma (cll/sll)
GB0216674D0 (en) * 2002-07-18 2002-08-28 Amersham Biosciences Uk Ltd Functional screening method
US8168568B1 (en) 2003-03-10 2012-05-01 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Combinatorial therapy for protein signaling diseases
GB2423988A (en) 2003-07-18 2006-09-13 Cytokinetics Inc Characterizing biological stimuli by response curves
US20050014217A1 (en) 2003-07-18 2005-01-20 Cytokinetics, Inc. Predicting hepatotoxicity using cell based assays
US7235353B2 (en) 2003-07-18 2007-06-26 Cytokinetics, Inc. Predicting hepatotoxicity using cell based assays
US20050060100A1 (en) * 2003-09-15 2005-03-17 Becton Dickinson And Company Computer software and algorithms for systems biologically linked to cellular phenotype
US20050059083A1 (en) * 2003-09-15 2005-03-17 Becton Dickinson And Company High throughput method to identify ligands for cell attachment
US20090227505A1 (en) * 2004-01-07 2009-09-10 Biotempt B.V. Methods and uses for protein breakdown products
US8586294B2 (en) 2004-05-18 2013-11-19 The Board Of Trustees Of The Leland Stanford Junior University Detection of protein translocation by beta-galactosidase reporter fragment complementation
US7323318B2 (en) 2004-07-15 2008-01-29 Cytokinetics, Inc. Assay for distinguishing live and dead cells
US8084260B2 (en) * 2004-11-24 2011-12-27 Applied Biosystems, Llc Spectral calibration method and system for multiple instruments
WO2007004869A2 (en) * 2005-07-05 2007-01-11 Biotempt B.V. Treatment of tumors
US20080227131A1 (en) * 2005-10-28 2008-09-18 Ge Healthcare Uk Limited Signalling Assay and Cell Line
US20090170091A1 (en) * 2006-01-17 2009-07-02 Kenneth Giuliano Method For Predicting Biological Systems Responses
EP1864692A1 (en) * 2006-06-07 2007-12-12 Biotempt B.V. Use of peptides for the control of radiation injury
CN101484806A (zh) 2006-05-17 2009-07-15 协乐民公司 一种对组织进行自动分析的方法
EP2095119A2 (en) * 2006-11-10 2009-09-02 Cellumen, Inc. Protein-protein interaction biosensors and methods of use thereof
US20100178652A1 (en) * 2007-01-05 2010-07-15 Litherland Sally A Materials and Methods for the Detection, Prevention and Treatment of Autoimmune Disease
DK2120991T3 (da) * 2007-02-12 2014-04-28 Biotempt Bv Behandling af traumatisk blødning med korte oligopeptider
US20080217002A1 (en) * 2007-03-07 2008-09-11 Floyd Randolph Simonds Sand control screen having a micro-perforated filtration layer
JP5438962B2 (ja) * 2008-12-25 2014-03-12 シスメックス株式会社 細胞画像表示装置
WO2010078290A2 (en) * 2008-12-29 2010-07-08 President And Fellows Of Harvard College System for screening agonists/antagonists of cellular signaling pathways
KR101088605B1 (ko) 2009-06-30 2011-11-30 한국산업기술대학교산학협력단 2대의 카메라를 이용한 세포 조작 방법
JP5089713B2 (ja) * 2010-01-18 2012-12-05 シャープ株式会社 画像圧縮装置、圧縮画像出力装置、画像圧縮方法、コンピュータプログラム及び記録媒体
ES2739623T3 (es) 2011-03-17 2020-02-03 Cernostics Inc Sistemas y composiciones para diagnosticar el esófago de Barrett y métodos para usarlos
WO2013138684A1 (en) 2012-03-15 2013-09-19 Montana Molecular Llc Genetically encoded fluorescent sensors for detecting intracellular signalling through diacylglycerol pathways
EP2682187B1 (en) * 2012-07-02 2017-09-13 Molecular Devices, LLC Selection method and apparatus
EP3738971B1 (en) 2013-11-04 2024-07-17 Montana Molecular LLC Genetically encoded fluorescent sensors for detecting ligand bias and intracellular signaling through camp pathways
DE102014012130B3 (de) 2014-08-13 2015-03-05 Alfred-Wegener-Institut, Helmholtz-Zentrum für Polar- und Meeresforschung Nachweisverfahren unter Verwendung von rekombinanten lebenden Zellen zum Nachweis von xenobiotischen Stoffen sowie Anordnung und Testkit zur Durchführung des Nachweisverfahrens
WO2022146025A1 (ko) * 2020-12-30 2022-07-07 한국과학기술원 암전이 억제 및 항암제 감수성 증진용 조성물

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT321257B (de) 1971-05-26 1975-03-25 Koreska Gmbh W Anlage zur Rückgewinnung flüchtiger Lösungsmittel
JPS57198544A (en) 1981-05-28 1982-12-06 Sony Corp Manufacture of magnetic recording medium
DE3240063A1 (de) 1981-11-02 1983-05-26 Basf Ag, 6700 Ludwigshafen Vorrichtung zur herstellung eines magnetogrammtraegers
JPS5880136A (ja) 1981-11-02 1983-05-14 Fuji Photo Film Co Ltd 磁気記録材料の製造方法
JPH0656656B2 (ja) 1983-10-03 1994-07-27 富士写真フイルム株式会社 磁気記録媒体の製造方法
JPS6292132A (ja) 1985-10-18 1987-04-27 Fuji Photo Film Co Ltd 磁気記録媒体の製造方法
US4923766A (en) 1988-03-29 1990-05-08 Canon Kabushiki Kaisha Process for preparing magnetic recording
GB8916806D0 (en) * 1989-07-22 1989-09-06 Univ Wales Medicine Modified proteins
DE4009797A1 (de) 1990-03-27 1991-10-02 Pagendarm Gmbh Verfahren und anordnung zum kondensieren von dampffoermigen substanzen
WO1994023039A1 (en) * 1993-04-07 1994-10-13 The Institute Of Cancer Research: Royal Cancer Hospital Methods for screening of substances for therapeutic activity and yeast for use therein
CA2169298A1 (en) * 1993-09-10 1995-03-16 Martin Chalfie Uses of green fluorescent protein
JP4215274B2 (ja) * 1994-07-22 2009-01-28 ザ ユニバーシティー オブ ノースカロライナ アット チャペル ヒル Ｓｒｃ ＳＨ３結合性ペプチドとその分離法と利用法
US6184205B1 (en) * 1994-07-22 2001-02-06 University Of North Carolina At Chapel Hill GRB2 SH3 binding peptides and methods of isolating and using same
US5874231A (en) * 1994-08-22 1999-02-23 Mcgill University Methods of screening for non-hormone compounds which effect modulation of polypeptide translation
US5958713A (en) 1995-01-31 1999-09-28 Novo Nordisk A/S Method of detecting biologically active substances by using green fluorescent protein
ATE211506T1 (de) * 1995-01-31 2002-01-15 Bioimage As Ein verfahren zum nachweis biologisch aktiver substanzen
DE69604298T2 (de) * 1995-09-22 2000-05-18 Bioimage A/S, Soeborg Varianten des grünen fluoreszenzproteins, gfp
CA2239951A1 (en) * 1995-12-08 1997-06-12 The Government Of The United States, Represented By The Secretary, Depar Tment Of Health And Human Services Method and compositions for monitoring dna binding molecules in living cells
US5874304A (en) * 1996-01-18 1999-02-23 University Of Florida Research Foundation, Inc. Humanized green fluorescent protein genes and methods
US5989835A (en) * 1997-02-27 1999-11-23 Cellomics, Inc. System for cell-based screening
AU3801997A (en) * 1996-07-16 1998-02-09 Regents Of The University Of California, The Assays for protein kinases using fluorescent protein substrates
AU5090498A (en) * 1997-01-07 1998-08-03 California Institute Of Technology Optical sensors of cell signaling
DE69839501D1 (de) * 1997-02-27 2008-06-26 Cellomics Inc System für Screening biologischer Zellen
US6416959B1 (en) * 1997-02-27 2002-07-09 Kenneth Giuliano System for cell-based screening
WO1998045704A2 (en) * 1997-04-07 1998-10-15 Bioimage A/S A method for extracting quantitative information relating to an influence on a cellular response
WO2000049183A1 (en) * 1999-02-17 2000-08-24 Clontech Laboratories, Inc. FLUORESCENCE RESONANCE ENERGY TRANSFER DETECTION OF cAMP IN LIVING CELLS USING GFP VARIANTS
US6573059B1 (en) * 1999-06-04 2003-06-03 Rmf Dictagene S.A. Use of the regulatory subunit of the camp dependent protein kinase (PKA) from dictyostelium for camp measurements

Also Published As

Publication number Publication date
DE69804446D1 (de) 2002-05-02
US20090023598A1 (en) 2009-01-22
WO1998045704A3 (en) 1999-04-22
ES2173573T3 (es) 2002-10-16
EP1199564A2 (en) 2002-04-24
EP0986753A2 (en) 2000-03-22
ATE354089T1 (de) 2007-03-15
US6518021B1 (en) 2003-02-11
CA2286293C (en) 2004-04-06
DE69837118T2 (de) 2007-12-27
US8058008B2 (en) 2011-11-15
DK1435519T3 (da) 2007-06-11
DE69804446T3 (de) 2006-08-24
DK0986753T4 (da) 2005-12-19
JP2001522454A (ja) 2001-11-13
EP0986753B1 (en) 2002-03-27
EP1435519A1 (en) 2004-07-07
EP1199564B1 (en) 2004-06-23
PT986753E (pt) 2002-09-30
EP1199564A3 (en) 2002-05-08
WO1998045704A2 (en) 1998-10-15
ES2173573T5 (es) 2006-03-01
ATE269975T1 (de) 2004-07-15
DK0986753T3 (da) 2002-07-22
DE69824763T2 (de) 2005-07-07
DE69837118D1 (de) 2007-03-29
ES2191575T1 (es) 2003-09-16
DE69824763D1 (de) 2004-07-29
ES2191575T3 (es) 2005-02-01
CA2286293A1 (en) 1998-10-15
DE1199564T1 (de) 2003-11-27
DE69804446T2 (de) 2002-11-07
EP1435519B1 (en) 2007-02-14
EP0986753B2 (en) 2005-08-10
US20030082564A1 (en) 2003-05-01
ATE215227T1 (de) 2002-04-15
PT1199564E (pt) 2004-10-29

Similar Documents

Publication Publication Date Title
DK0986753T4 (da) Fremgangsmåde til uddragning af kvantitativ information, hvad angår en påvirkning af et cellulært respons
Turkowyd et al. A general mechanism of photoconversion of green‐to‐red fluorescent proteins based on blue and infrared light reduces phototoxicity in live‐cell single‐molecule imaging
Garcia-Parajo et al. The nature of fluorescence emission in the red fluorescent protein DsRed, revealed by single-molecule detection
Yu et al. In vitro and intracellular production of peptide-encapsulated fluorescent silver nanoclusters
Arcese et al. The form and function of song in female song sparrows
Ando et al. An optical marker based on the UV-induced green-to-red photoconversion of a fluorescent protein
Chen et al. Characterization of spectral FRET imaging microscopy for monitoring nuclear protein interactions
Lippincott-Schwartz et al. Development and use of fluorescent protein markers in living cells
Slater et al. Global record of “ghost” nannofossils reveals plankton resilience to high CO2 and warming
EP1653220A3 (en) Biochip reader
DE50210457D1 (de) Vorrichtung zur referenzierung von fluoreszenzsignalen
Modenutti et al. Mixotrophic ciliates in an Andean lake: dependence on light and prey of an Ophrydium naumanni population
Rodionova et al. Progress in the study of bioluminescent earthworms
Smit et al. Reverse intersystem crossing of single deuterated perylene molecules in a dibenzothiophene matrix
Gay et al. Alignment of EphA4 and ephrin‐B2 expression patterns with developing modularity in the lateral cortex of the inferior colliculus
Vánská et al. Photosystem II supercomplexes lacking light‐harvesting antenna protein LHCB5 and their organization in the thylakoid membrane
Gronauer et al. A photocrosslinking probe to capture the substrates of caseinolytic protease P
EP0990896A3 (en) Large area image analysing apparatus
Tuson et al. Addressing the Requirements of High‐Sensitivity Single‐Molecule Imaging of Low‐Copy‐Number Proteins in Bacteria
Wallrabe et al. IQGAP1 interactome analysis by in vitro reconstitution and live cell 3‐color FRET microscopy
Krauchunas et al. C. elegans CYLC-2 localizes to sperm
Teranishi Identification of possible light emitters in the gills of a bioluminescent fungus Mycena chlorophos
Lin et al. Superior robustness of ExEm‐spFRET to IIem‐spFRET method in live‐cell FRET measurement
Takatsu et al. Detection of pretreated fingerprint fluorescence using an LED‐based excitation system
Coulson et al. On the Collembola, Araneae and Gamasida from the Kinnvika region of Nordaustlandet, Svalbard