AU640449B2 - Condensed thiazole compounds, their production and use - Google Patents

Condensed thiazole compounds, their production and use Download PDF

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Publication number
AU640449B2
AU640449B2 AU71243/91A AU7124391A AU640449B2 AU 640449 B2 AU640449 B2 AU 640449B2 AU 71243/91 A AU71243/91 A AU 71243/91A AU 7124391 A AU7124391 A AU 7124391A AU 640449 B2 AU640449 B2 AU 640449B2
Authority
AU
Australia
Prior art keywords
compound
group
salt
compound according
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU71243/91A
Other languages
English (en)
Other versions
AU7124391A (en
Inventor
Tetsuya Aona
Go Kito
Masahiro Suno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of AU7124391A publication Critical patent/AU7124391A/en
Application granted granted Critical
Publication of AU640449B2 publication Critical patent/AU640449B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AU71243/91A 1990-02-23 1991-02-20 Condensed thiazole compounds, their production and use Ceased AU640449B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2-44095 1990-02-23
JP4409590 1990-02-23
JP25965690 1990-09-27
JP2-259656 1990-09-27

Publications (2)

Publication Number Publication Date
AU7124391A AU7124391A (en) 1991-08-29
AU640449B2 true AU640449B2 (en) 1993-08-26

Family

ID=26383943

Family Applications (1)

Application Number Title Priority Date Filing Date
AU71243/91A Ceased AU640449B2 (en) 1990-02-23 1991-02-20 Condensed thiazole compounds, their production and use

Country Status (11)

Country Link
US (1) US5153201A (enExample)
EP (1) EP0443588B1 (enExample)
KR (1) KR910021406A (enExample)
AT (1) ATE181553T1 (enExample)
AU (1) AU640449B2 (enExample)
CA (1) CA2036905C (enExample)
DE (1) DE69131359T2 (enExample)
IE (1) IE910570A1 (enExample)
IL (1) IL97249A (enExample)
NZ (1) NZ237187A (enExample)
TW (1) TW206970B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5857296A (en) * 1995-05-17 1996-11-29 Eli Lilly And Company Use of leukotriene antagonists for alzheimer's disease
US5653903A (en) * 1995-06-27 1997-08-05 Ppg Industries, Inc. L-shaped heating element with radiused end for a windshield
US5886321A (en) * 1996-12-19 1999-03-23 Ppg Industries, Inc. Arrangement for heating the wiper rest area of a vehicle windshield
GB2418427A (en) 2004-09-02 2006-03-29 Univ Cambridge Tech Ligands for G-protein coupled receptors
WO2006076569A2 (en) * 2005-01-12 2006-07-20 Bristol-Myers Squibb Company Bicyclic heterocycles as cannabinoid receptor modulators
GB2452696B (en) 2007-08-02 2009-09-23 Cambridge Entpr Ltd 3-(2',2'-dimethylpropanoylamino)-tetrahydropyridin-2-one and its use in pharmaceutical compositions
US7662967B2 (en) 2007-08-02 2010-02-16 Cambridge Enterprise Limited Anti-inflammatory compounds and compositions
US8513230B2 (en) 2010-03-05 2013-08-20 Karyopharm Therapeutics, Inc. Nuclear transport modulators and uses thereof
CN103402359B (zh) 2011-01-17 2016-08-24 卡尔约药物治疗公司 含烯烃核运输调节剂及其用途
EP2736883B1 (en) * 2011-07-29 2019-09-04 Karyopharm Therapeutics, Inc. Nuclear transport modulators and uses thereof
EP2736887B1 (en) 2011-07-29 2017-10-18 Karyopharm Therapeutics, Inc. Hydrazide containing nuclear transport modulators and uses thereof
IN2014DN09434A (enExample) 2012-05-09 2015-07-17 Karyopharm Therapeutics Inc
WO2014144772A1 (en) 2013-03-15 2014-09-18 Karyopharm Therapeutics Inc. Methods of promoting wound healing using crm1 inhibitors
CN110386919B (zh) 2013-06-21 2023-07-14 卡尔约药物治疗公司 核转运调节剂及其用途
CN111484483B (zh) 2014-08-15 2023-05-26 卡尔约药物治疗公司 赛灵克斯的多晶型物
US10526295B2 (en) 2015-12-31 2020-01-07 Karyopharm Therapeutics Inc. Nuclear transport modulators and uses thereof
EP3397634A1 (en) 2015-12-31 2018-11-07 Karyopharm Therapeutics, Inc. Nuclear transport modulators and uses thereof
US11602530B2 (en) 2016-11-28 2023-03-14 Biogen Ma Inc. CRM1 inhibitors for treating epilepsy
CN109134510A (zh) * 2018-11-13 2019-01-04 井冈山大学 制备2-氨基-5-cbz-4,5,6,7-四氢噻唑并[5，4-c]吡啶的新方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3714175A (en) * 1970-08-14 1973-01-30 Tanabe Seiyaku Co Certain-1-aryl-3-substituted benzamido-2-pyrrolidinones
DE3211973A1 (de) * 1981-04-24 1982-11-11 CRC Compagnia di Ricerca Chimica S.p.A., S. Giovanni al Natisone, Udine Verfahren zur herstellung eines pyrido-(2,3-b)-(1,4)benzodiazepins

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3545097A1 (de) * 1985-12-19 1987-07-02 Bayer Ag 1-h-pyrido-(3,2-b)(1,4)-thiazine
DE3701737A1 (de) * 1987-01-22 1988-08-04 Bayer Ag 1h-pyrido-(2,3-b)(1,4)-thiazine zur therapeutischen behandlung
DK196688A (da) * 1987-04-28 1988-10-29 Fujisawa Pharmaceutical Co Bicykliske forbindelser og fremgangsmaade til fremstilling deraf
FI91859C (fi) * 1987-06-17 1994-08-25 Eisai Co Ltd Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi
MX13484A (es) * 1987-10-19 1993-05-01 Pfizer Procedimiento para la obtencion de tetralinas, cromanos y compuestos relacionados, sustituidos
US4859776A (en) * 1988-03-11 1989-08-22 Abbott Laboratories (S)-7-(3-aminopyrrolidin-1-yl)-1-(ortho, para-difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid and method for its preparation
JP3054738B2 (ja) * 1988-07-22 2000-06-19 武田薬品工業株式会社 チアゾロ［５，４―ｂ］アゼピン誘導体

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3714175A (en) * 1970-08-14 1973-01-30 Tanabe Seiyaku Co Certain-1-aryl-3-substituted benzamido-2-pyrrolidinones
DE3211973A1 (de) * 1981-04-24 1982-11-11 CRC Compagnia di Ricerca Chimica S.p.A., S. Giovanni al Natisone, Udine Verfahren zur herstellung eines pyrido-(2,3-b)-(1,4)benzodiazepins

Also Published As

Publication number Publication date
NZ237187A (en) 1992-10-28
IL97249A (en) 1995-01-24
EP0443588B1 (en) 1999-06-23
IE910570A1 (en) 1991-08-28
DE69131359T2 (de) 1999-10-14
KR910021406A (ko) 1991-12-20
TW206970B (enExample) 1993-06-01
CA2036905A1 (en) 1991-08-24
CA2036905C (en) 2003-05-06
AU7124391A (en) 1991-08-29
EP0443588A1 (en) 1991-08-28
IL97249A0 (en) 1992-05-25
US5153201A (en) 1992-10-06
ATE181553T1 (de) 1999-07-15
DE69131359D1 (de) 1999-07-29

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