TW206970B - - Google Patents

Info

Publication number
TW206970B
TW206970B TW080101248A TW80101248A TW206970B TW 206970 B TW206970 B TW 206970B TW 080101248 A TW080101248 A TW 080101248A TW 80101248 A TW80101248 A TW 80101248A TW 206970 B TW206970 B TW 206970B
Authority
TW
Taiwan
Prior art keywords
compound
formula
salt
optionally substituted
hydrogen atom
Prior art date
Application number
TW080101248A
Other languages
English (en)
Original Assignee
Takeda Pharm Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharm Industry Co Ltd filed Critical Takeda Pharm Industry Co Ltd
Application granted granted Critical
Publication of TW206970B publication Critical patent/TW206970B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
TW080101248A 1990-02-23 1991-02-20 TW206970B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4409590 1990-02-23
JP25965690 1990-09-27

Publications (1)

Publication Number Publication Date
TW206970B true TW206970B (zh) 1993-06-01

Family

ID=26383943

Family Applications (1)

Application Number Title Priority Date Filing Date
TW080101248A TW206970B (zh) 1990-02-23 1991-02-20

Country Status (11)

Country Link
US (1) US5153201A (zh)
EP (1) EP0443588B1 (zh)
KR (1) KR910021406A (zh)
AT (1) ATE181553T1 (zh)
AU (1) AU640449B2 (zh)
CA (1) CA2036905C (zh)
DE (1) DE69131359T2 (zh)
IE (1) IE910570A1 (zh)
IL (1) IL97249A (zh)
NZ (1) NZ237187A (zh)
TW (1) TW206970B (zh)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0743064A1 (en) * 1995-05-17 1996-11-20 Eli Lilly And Company Leukotriene antagonists for use in the treatment or prevention of alzheimer's disease
US5653903A (en) * 1995-06-27 1997-08-05 Ppg Industries, Inc. L-shaped heating element with radiused end for a windshield
US5886321A (en) * 1996-12-19 1999-03-23 Ppg Industries, Inc. Arrangement for heating the wiper rest area of a vehicle windshield
GB2418427A (en) 2004-09-02 2006-03-29 Univ Cambridge Tech Ligands for G-protein coupled receptors
US7361766B2 (en) 2005-01-12 2008-04-22 Bristol-Myers Squibb Company Bicyclic heterocycles as cannabinoid receptor modulators
US7662967B2 (en) 2007-08-02 2010-02-16 Cambridge Enterprise Limited Anti-inflammatory compounds and compositions
GB2452696B (en) 2007-08-02 2009-09-23 Cambridge Entpr Ltd 3-(2',2'-dimethylpropanoylamino)-tetrahydropyridin-2-one and its use in pharmaceutical compositions
AU2011222531B2 (en) 2010-03-05 2015-03-26 Karyopharm Therapeutics, Inc. Nuclear transport modulatiors and uses thereof
AU2012207565B2 (en) 2011-01-17 2016-04-07 Karyopharm Therapeutics Inc. Olefin containing nuclear transport modulators and uses thereof
PL2736887T3 (pl) 2011-07-29 2018-03-30 Karyopharm Therapeutics, Inc. Modulatory transportu jądrowego zawierające ugrupowanie hydrazydu i ich zastosowania
WO2013019561A1 (en) * 2011-07-29 2013-02-07 Karyopharm Therapeutics, Inc. Nuclear transport modulators and uses thereof
LT2858991T (lt) 2012-05-09 2018-11-26 Biogen Ma Inc. Branduolinio transporto moduliatoriai ir jų panaudojimas
EP2968278B8 (en) 2013-03-15 2019-05-22 Karyopharm Therapeutics Inc. Methods of promoting wound healing using crm1 inhibitors
BR112015032071B1 (pt) 2013-06-21 2022-06-14 Karyopharm Therapeutics Inc Modulares do transporte nuclear e suas utilizações
CN111481553B (zh) 2014-08-15 2023-09-01 卡尔约药物治疗公司 赛灵克斯的多晶型物
EP3397634A1 (en) 2015-12-31 2018-11-07 Karyopharm Therapeutics, Inc. Nuclear transport modulators and uses thereof
MA43529A (fr) 2015-12-31 2018-11-07 Karyopharm Therapeutics Inc Modulateurs de transport nucléaire et leurs utilisations
WO2018098472A1 (en) 2016-11-28 2018-05-31 Karyopharm Therapeutics Inc. Crm1 inhibitors for treating epilepsy
CN109134510A (zh) * 2018-11-13 2019-01-04 井冈山大学 制备2-氨基-5-cbz-4,5,6,7-四氢噻唑并[5，4-c]吡啶的新方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4924916B1 (zh) * 1970-08-14 1974-06-26
IT1211027B (it) * 1981-04-24 1989-09-29 Crc Ricerca Chim Pina procedimento per la preparazione di _ una pirido-[2,3-b][1,4]benzodiaze
DE3545097A1 (de) * 1985-12-19 1987-07-02 Bayer Ag 1-h-pyrido-(3,2-b)(1,4)-thiazine
DE3701737A1 (de) * 1987-01-22 1988-08-04 Bayer Ag 1h-pyrido-(2,3-b)(1,4)-thiazine zur therapeutischen behandlung
DK196688A (da) * 1987-04-28 1988-10-29 Fujisawa Pharmaceutical Co Bicykliske forbindelser og fremgangsmaade til fremstilling deraf
FI91859C (fi) * 1987-06-17 1994-08-25 Eisai Co Ltd Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi
MX13484A (es) * 1987-10-19 1993-05-01 Pfizer Procedimiento para la obtencion de tetralinas, cromanos y compuestos relacionados, sustituidos
US4859776A (en) * 1988-03-11 1989-08-22 Abbott Laboratories (S)-7-(3-aminopyrrolidin-1-yl)-1-(ortho, para-difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid and method for its preparation
JP3054738B2 (ja) * 1988-07-22 2000-06-19 武田薬品工業株式会社 チアゾロ［５，４―ｂ］アゼピン誘導体

Also Published As

Publication number Publication date
IL97249A (en) 1995-01-24
DE69131359T2 (de) 1999-10-14
CA2036905A1 (en) 1991-08-24
EP0443588A1 (en) 1991-08-28
EP0443588B1 (en) 1999-06-23
KR910021406A (ko) 1991-12-20
CA2036905C (en) 2003-05-06
AU640449B2 (en) 1993-08-26
AU7124391A (en) 1991-08-29
IE910570A1 (en) 1991-08-28
ATE181553T1 (de) 1999-07-15
IL97249A0 (en) 1992-05-25
DE69131359D1 (de) 1999-07-29
US5153201A (en) 1992-10-06
NZ237187A (en) 1992-10-28

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