AU6291498A - Measurement device and its use - Google Patents
Measurement device and its useInfo
- Publication number
- AU6291498A AU6291498A AU62914/98A AU6291498A AU6291498A AU 6291498 A AU6291498 A AU 6291498A AU 62914/98 A AU62914/98 A AU 62914/98A AU 6291498 A AU6291498 A AU 6291498A AU 6291498 A AU6291498 A AU 6291498A
- Authority
- AU
- Australia
- Prior art keywords
- excitation radiation
- wave
- cavity
- layer
- guiding layer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000005259 measurement Methods 0.000 title 1
- 230000005855 radiation Effects 0.000 abstract 5
- 230000005284 excitation Effects 0.000 abstract 4
- 230000035515 penetration Effects 0.000 abstract 2
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 238000007789 sealing Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/05—Flow-through cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Optical Measuring Cells (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Inspection Of Paper Currency And Valuable Securities (AREA)
- Preliminary Treatment Of Fibers (AREA)
- Optical Couplings Of Light Guides (AREA)
- Optical Integrated Circuits (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96810807 | 1996-11-18 | ||
| EP96810808 | 1996-11-18 | ||
| EP96810808A EP0843173A1 (de) | 1996-11-18 | 1996-11-18 | Flusszelle sowie Vorrichtung zur Erzeugung evaneszent angeregter Strahlung |
| EP96810807A EP0843172A1 (de) | 1996-11-18 | 1996-11-18 | Flusszelle sowie Vorrichtung zur Erzeugung evaneszent angeregter Strahlung |
| PCT/EP1997/006443 WO1998022799A2 (de) | 1996-11-18 | 1997-11-18 | Messvorrichtung und deren verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU6291498A true AU6291498A (en) | 1998-06-10 |
Family
ID=26144278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU62914/98A Abandoned AU6291498A (en) | 1996-11-18 | 1997-11-18 | Measurement device and its use |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US6198869B1 (enExample) |
| EP (1) | EP0938656B1 (enExample) |
| JP (1) | JP3748571B2 (enExample) |
| AT (1) | ATE308039T1 (enExample) |
| AU (1) | AU6291498A (enExample) |
| DE (1) | DE59712460D1 (enExample) |
| WO (1) | WO1998022799A2 (enExample) |
Families Citing this family (77)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4662623B2 (ja) * | 1998-02-05 | 2011-03-30 | ノバルティス アーゲー | ルミネッセンスを測定する方法及び装置 |
| FR2783919A1 (fr) * | 1998-09-25 | 2000-03-31 | Suisse Electronique Microtech | Capteur optique integre pour detecter les composants d'un fluide |
| EP1131659A4 (en) * | 1998-10-29 | 2005-02-02 | Mark Stephen Braiman | GERMANIUM, QUASI PLANAIRES, A DECREASING SECTION WAVEGUIDES FOR MEDIUM INFRARED DETECTION |
| DE19856041A1 (de) * | 1998-12-04 | 2000-07-13 | Inst Chemo Biosensorik | Verfahren und Vorrichtung zur Durchführung von quantitativen Fluoreszenz markierten Affinitätstests |
| US6225109B1 (en) * | 1999-05-27 | 2001-05-01 | Orchid Biosciences, Inc. | Genetic analysis device |
| EP1192448B1 (en) | 1999-07-05 | 2006-09-27 | Novartis AG | Process of using a sensor platform |
| US6771376B2 (en) * | 1999-07-05 | 2004-08-03 | Novartis Ag | Sensor platform, apparatus incorporating the platform, and process using the platform |
| WO2001013096A1 (de) | 1999-08-13 | 2001-02-22 | Zeptosens Ag | Vorrichtung und verfahren zur multianalytbestimmung |
| JP2003507736A (ja) † | 1999-08-20 | 2003-02-25 | スティフチュンク フュル ディアグノスティシュ フォルシュンク | エバネッセンス場法を用いて物質を測定する方法 |
| DE19948087B4 (de) * | 1999-10-06 | 2008-04-17 | Evotec Ag | Verfahren zur Herstellung eines Reaktionssubstrats |
| US7167615B1 (en) | 1999-11-05 | 2007-01-23 | Board Of Regents, The University Of Texas System | Resonant waveguide-grating filters and sensors and methods for making and using same |
| US6592733B1 (en) * | 1999-11-12 | 2003-07-15 | Motorola, Inc. | Capillary electrophoresis devices incorporating optical waveguides |
| JP4599019B2 (ja) | 1999-12-17 | 2010-12-15 | バイエル・テクノロジー・サービシーズ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | フローセル配列及び多重分析対象物測定のためのその利用 |
| US6580507B2 (en) * | 2000-03-02 | 2003-06-17 | Sd Acquisition Inc. | Single source, single detector chip, multiple-longitudinal channel electromagnetic radiation absorbance and fluorescence monitoring system |
| EP1281063A1 (de) * | 2000-05-06 | 2003-02-05 | Zeptosens AG | Gitter-wellenleiter-struktur für multianalytbestimmungen und deren verwendung |
| WO2001092870A2 (de) | 2000-06-02 | 2001-12-06 | Zeptosens Ag | Kit und verfahren zur multianalytbestimmung |
| US7158224B2 (en) * | 2000-06-25 | 2007-01-02 | Affymetrix, Inc. | Optically active substrates |
| DE10058095C2 (de) * | 2000-11-03 | 2003-12-18 | Fraunhofer Ges Forschung | Vorrichtung zur Bestimmung von Analyten durch Chemilumineszenz |
| EP1405056A1 (de) * | 2001-06-15 | 2004-04-07 | Zeptosens AG | Körper für durchflussküvetten und deren verwendung |
| GB0207944D0 (en) * | 2002-04-05 | 2002-05-15 | Univ Cambridge Tech | Method of detection |
| US20030232427A1 (en) * | 2002-06-18 | 2003-12-18 | Montagu Jean I. | Optically active substrates for examination of biological materials |
| DE10307802A1 (de) * | 2003-02-24 | 2004-09-09 | Advalytix Ag | Analyseverfahren und -Vorrichtung zur Analyse von spezifischen Bindungsreaktionen |
| US7545494B2 (en) * | 2003-07-23 | 2009-06-09 | Bayer Technology Services Gmbh | Analytical system and method for analyzing nonlinear optical signals |
| DE102004039564B4 (de) * | 2004-08-13 | 2006-06-29 | Institut für Lasertechnologien in der Medizin und Meßtechnik an der Universität Ulm | Vorrichtung zum optischen Screening von Oberflächen biologischer Proben in zweidimensionaler Anordnung |
| US7095941B2 (en) * | 2004-10-27 | 2006-08-22 | Schott Corporation | Fused optical fiber optical device system |
| JP2006162538A (ja) * | 2004-12-10 | 2006-06-22 | Seiko Instruments Inc | 微量質量測定装置 |
| GB0501944D0 (en) | 2005-01-31 | 2005-03-09 | Univ Cambridge Tech | Compounds for use in chemical detection and/or quantitation |
| JP4290128B2 (ja) * | 2005-02-25 | 2009-07-01 | キヤノン株式会社 | センサ |
| US20070196863A1 (en) * | 2006-02-17 | 2007-08-23 | Hanson Technologies, Inc. | Prion protein detection |
| US7951583B2 (en) * | 2006-03-10 | 2011-05-31 | Plc Diagnostics, Inc. | Optical scanning system |
| US9976192B2 (en) | 2006-03-10 | 2018-05-22 | Ldip, Llc | Waveguide-based detection system with scanning light source |
| US9528939B2 (en) | 2006-03-10 | 2016-12-27 | Indx Lifecare, Inc. | Waveguide-based optical scanning systems |
| US9423397B2 (en) | 2006-03-10 | 2016-08-23 | Indx Lifecare, Inc. | Waveguide-based detection system with scanning light source |
| US8288157B2 (en) * | 2007-09-12 | 2012-10-16 | Plc Diagnostics, Inc. | Waveguide-based optical scanning systems |
| US8207509B2 (en) | 2006-09-01 | 2012-06-26 | Pacific Biosciences Of California, Inc. | Substrates, systems and methods for analyzing materials |
| US7639355B2 (en) * | 2007-06-26 | 2009-12-29 | Hewlett-Packard Development Company, L.P. | Electric-field-enhancement structure and detection apparatus using same |
| DE102007033124B4 (de) * | 2007-07-16 | 2012-12-06 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Vorrichtung zur optischen Detektion von Substanzen in einem flüssigen oder gasförmigen Medium |
| JP2009133836A (ja) * | 2007-11-06 | 2009-06-18 | Toshiba Corp | 光学式センサ |
| US7860354B2 (en) * | 2007-11-06 | 2010-12-28 | Kabushiki Kaisha Toshiba | Optical sensor |
| EP2110694B1 (en) | 2008-04-18 | 2013-08-14 | Sony DADC Austria AG | Method for manufacturing an optical waveguide, optical waveguide, and sensor arrangement |
| GB2461026B (en) * | 2008-06-16 | 2011-03-09 | Plc Diagnostics Inc | System and method for nucleic acids sequencing by phased synthesis |
| CA3063032A1 (en) | 2008-09-16 | 2010-03-25 | Pacific Biosciences Of California, Inc. | Substrates and optical systems and methods of use thereof |
| JP2010151510A (ja) * | 2008-12-24 | 2010-07-08 | Tdk Corp | 液性測定装置 |
| US8300993B2 (en) * | 2009-03-02 | 2012-10-30 | Mbio Diagnostics, Inc. | Waveguide with integrated lens |
| US9658222B2 (en) | 2009-03-02 | 2017-05-23 | Mbio Diagnostics, Inc. | Planar waveguide based cartridges and associated methods for detecting target analyte |
| US8331751B2 (en) * | 2009-03-02 | 2012-12-11 | mBio Diagnositcs, Inc. | Planar optical waveguide with core of low-index-of-refraction interrogation medium |
| US9212995B2 (en) | 2009-03-02 | 2015-12-15 | Mbio Diagnostics, Inc. | System and method for detecting multiple molecules in one assay |
| JP5757535B2 (ja) * | 2009-04-29 | 2015-07-29 | ピーエルシー ダイアグノスティクス, インコーポレイテッド | 走査光源による導波管に基づく検出システム |
| JP5272965B2 (ja) * | 2009-08-19 | 2013-08-28 | 株式会社島津製作所 | 蛍光検出器 |
| US9410891B2 (en) | 2010-02-19 | 2016-08-09 | Pacific Biosciences Of California, Inc. | Optics collection and detection system and method |
| US8994946B2 (en) | 2010-02-19 | 2015-03-31 | Pacific Biosciences Of California, Inc. | Integrated analytical system and method |
| BR112013000210A8 (pt) * | 2010-07-09 | 2016-09-06 | Koninklijke Philips Eletronics N V | Cartucho para exames óticos de amostra, método de produção de cartucho e aparelho de exame para exames de amostra em cartucho |
| EP2616797B1 (en) | 2010-09-15 | 2017-01-11 | MBIO Diagnostics Inc. | System and method for detecting multiple molecules in one assay |
| US8750652B2 (en) * | 2010-10-12 | 2014-06-10 | The Board Of Trustees Of The Leland Stanford Junior University | Microfluidic waveguide detector |
| WO2012068499A2 (en) | 2010-11-19 | 2012-05-24 | The Regents Of The University Of California | Hybrid, planar optofluidic integration |
| WO2013035028A1 (en) * | 2011-09-06 | 2013-03-14 | Koninklijke Philips Electronics N.V. | Method and device for coupling a light beam into a foil |
| US20140379299A1 (en) * | 2012-01-18 | 2014-12-25 | Jawaharlal Nehru Centre For Advanced Scientific Research | System and a method to detect hydrogen leakage using nano-crystallized palladium gratings |
| JP6673843B2 (ja) | 2013-11-17 | 2020-03-25 | クアンタム−エスアイ インコーポレイテッドQuantum−Si Incorporated | 分子をプローブし、検出し、分析するための光学システム及びアッセイ・チップ |
| US10018566B2 (en) | 2014-02-28 | 2018-07-10 | Ldip, Llc | Partially encapsulated waveguide based sensing chips, systems and methods of use |
| EP2916125A1 (en) * | 2014-03-07 | 2015-09-09 | One Drop Diagnostics Sàrl | Fluorescence-detected assays on microfluidic chips |
| CA2957546A1 (en) * | 2014-08-08 | 2016-02-11 | Quantum-Si Incorporated | Integrated device with external light source for probing, detecting, and analyzing molecules |
| US10174363B2 (en) | 2015-05-20 | 2019-01-08 | Quantum-Si Incorporated | Methods for nucleic acid sequencing |
| MX383892B (es) | 2014-08-08 | 2025-03-14 | Quantum Si Inc | Sistema optico y circuito integrado de valoración para sondear, detectar y analizar moleculas. |
| EP3194935B1 (en) | 2014-08-08 | 2018-10-31 | Quantum-si Incorporated | Integrated device for temporal binning of received photons |
| WO2016138427A1 (en) | 2015-02-27 | 2016-09-01 | Indx Lifecare, Inc. | Waveguide-based detection system with scanning light source |
| EP3292220B1 (en) | 2015-05-07 | 2022-07-13 | Pacific Biosciences of California, Inc. | Multiprocessor pipeline architecture |
| EP3317641B1 (en) * | 2015-06-30 | 2019-03-06 | IMEC vzw | Radiation carrier and use thereof in an optical sensor |
| US10441174B2 (en) | 2016-02-17 | 2019-10-15 | Tesseract Health, Inc. | Sensor and device for lifetime imaging and detection applications |
| TWI836905B (zh) | 2016-12-22 | 2024-03-21 | 美商寬騰矽公司 | 具有直接合併像素之整合式光電偵測器 |
| JP7343875B2 (ja) | 2017-02-28 | 2023-09-13 | ザ リージェンツ オブ ザ ユニヴァーシティ オブ カリフォルニア | マルチモード干渉導波路を用いるオプトフルイディックアナライト検出システム |
| TW201915473A (zh) | 2017-07-24 | 2019-04-16 | 美商寬騰矽公司 | 手持,大量平行之生物光電裝置 |
| CA3108295A1 (en) | 2018-06-22 | 2019-12-26 | Quantum-Si Incorporated | Integrated photodetector with charge storage bin of varied detection time |
| US11994504B2 (en) | 2020-09-18 | 2024-05-28 | Salvus, Llc | Interferometric detection and quantification system and methods of use in food processing and food supply chain |
| US20220091031A1 (en) * | 2020-09-18 | 2022-03-24 | Salvus, Llc | Interferometric Detection and Quantification System and Methods of Use in Chemical Processing |
| US12399172B2 (en) | 2020-09-18 | 2025-08-26 | Salvus, Llc | Interferometric detection and quantification system and methods of use in healthcare |
| US11740177B2 (en) | 2020-09-18 | 2023-08-29 | Salvus, Llc | Interferometric detection and quantification system and methods of use in aquatics |
| DE102020133924A1 (de) | 2020-12-17 | 2022-06-23 | Carl Zeiss Jena Gmbh | Chiplabor-system mit funktionalisiertem wellenleiter |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3481644D1 (de) * | 1984-12-10 | 1990-04-19 | Prutec Ltd | Verfahren zum optischen nachweis von parametern von substanzen in einem fluessigen analyt. |
| SE462408B (sv) * | 1988-11-10 | 1990-06-18 | Pharmacia Ab | Optiskt biosensorsystem utnyttjande ytplasmonresonans foer detektering av en specific biomolekyl, saett att kalibrera sensoranordningen samt saett att korrigera foer baslinjedrift i systemet |
| US5830766A (en) * | 1990-05-23 | 1998-11-03 | Ares-Serono Research & Development Ltd. Partnership | Enhanced signal-to-noise ratio and sensitivity optical immunoassay |
| US5512492A (en) * | 1993-05-18 | 1996-04-30 | University Of Utah Research Foundation | Waveguide immunosensor with coating chemistry providing enhanced sensitivity |
| US5677196A (en) * | 1993-05-18 | 1997-10-14 | University Of Utah Research Foundation | Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays |
| DE69505370T2 (de) | 1994-05-27 | 1999-04-01 | Novartis Ag, Basel | Verfahren und sensor zum nachweis abklingend angeregter lumineszenz |
| MX9708698A (es) | 1995-05-12 | 1998-02-28 | Novartis Ag | Plataforma de sensor y metodo para la deteccion paralela de una pluralidad de analitos utilizando luminescencia evanescentemente excitada. |
| WO1997001087A1 (en) * | 1995-06-23 | 1997-01-09 | Novartis Ag | Flow cell |
| JP3886153B2 (ja) * | 1996-03-19 | 2007-02-28 | ユニバーシティー オブ ユタ リサーチ ファンデーション | レンズおよび連結可能なフローセル |
| JP3266041B2 (ja) * | 1996-05-22 | 2002-03-18 | 株式会社島津製作所 | 部材接合法及びこの方法により製造した光学測定装置 |
| DE19628002C1 (de) * | 1996-07-11 | 1997-12-18 | Inst Chemo Biosensorik | Vorrichtung und Verfahren zur Durchführung von Fluoreszenzimmunotests |
| US5832165A (en) * | 1996-08-28 | 1998-11-03 | University Of Utah Research Foundation | Composite waveguide for solid phase binding assays |
-
1997
- 1997-11-18 WO PCT/EP1997/006443 patent/WO1998022799A2/de not_active Ceased
- 1997-11-18 AT AT97954883T patent/ATE308039T1/de not_active IP Right Cessation
- 1997-11-18 AU AU62914/98A patent/AU6291498A/en not_active Abandoned
- 1997-11-18 EP EP97954883A patent/EP0938656B1/de not_active Expired - Lifetime
- 1997-11-18 DE DE59712460T patent/DE59712460D1/de not_active Expired - Lifetime
- 1997-11-18 JP JP52320998A patent/JP3748571B2/ja not_active Expired - Fee Related
- 1997-11-18 US US09/308,096 patent/US6198869B1/en not_active Expired - Lifetime
-
2000
- 2000-12-22 US US09/742,391 patent/US6384912B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE308039T1 (de) | 2005-11-15 |
| DE59712460D1 (de) | 2005-12-01 |
| WO1998022799A2 (de) | 1998-05-28 |
| US6198869B1 (en) | 2001-03-06 |
| US20010001021A1 (en) | 2001-05-10 |
| JP2001504230A (ja) | 2001-03-27 |
| EP0938656A2 (de) | 1999-09-01 |
| US6384912B2 (en) | 2002-05-07 |
| EP0938656B1 (de) | 2005-10-26 |
| WO1998022799A3 (de) | 1998-08-20 |
| JP3748571B2 (ja) | 2006-02-22 |
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