AU622099B2 - Method of affinity purification employing monoclonal antibodies - Google Patents
Method of affinity purification employing monoclonal antibodies Download PDFInfo
- Publication number
- AU622099B2 AU622099B2 AU72569/87A AU7256987A AU622099B2 AU 622099 B2 AU622099 B2 AU 622099B2 AU 72569/87 A AU72569/87 A AU 72569/87A AU 7256987 A AU7256987 A AU 7256987A AU 622099 B2 AU622099 B2 AU 622099B2
- Authority
- AU
- Australia
- Prior art keywords
- environment
- antigen
- antibody
- process according
- antibodies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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- 238000001261 affinity purification Methods 0.000 title description 6
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- BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 description 1
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- HOVAGTYPODGVJG-VEIUFWFVSA-N methyl alpha-D-mannoside Chemical compound CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O HOVAGTYPODGVJG-VEIUFWFVSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36778182A | 1982-04-12 | 1982-04-12 | |
| US367781 | 1982-04-12 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU15507/83A Division AU1550783A (en) | 1982-04-12 | 1983-04-12 | Method of affinity purification employing monoclonal antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU7256987A AU7256987A (en) | 1987-09-03 |
| AU622099B2 true AU622099B2 (en) | 1992-04-02 |
Family
ID=23448565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU72569/87A Ceased AU622099B2 (en) | 1982-04-12 | 1987-05-06 | Method of affinity purification employing monoclonal antibodies |
Country Status (11)
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8328918D0 (en) * | 1983-10-28 | 1983-11-30 | Unilever Plc | Alkaline phosphatase |
| GB8331071D0 (en) * | 1983-11-22 | 1983-12-29 | Karayiannis P | Assay for dna/rna |
| US4666865A (en) * | 1984-01-13 | 1987-05-19 | Centocor, Inc. | Immunoassay for biologically active human interferon-gamma employing unique monoclonal antibodies |
| US4789631A (en) * | 1984-02-17 | 1988-12-06 | Synbiotics Corporation | Immunoassay for anti-dirofilaria immitis antibody |
| GB8426468D0 (en) * | 1984-10-19 | 1984-11-28 | Technology Licence Co Ltd | Monoclonal antibodies |
| AU5259786A (en) * | 1985-01-30 | 1986-08-07 | United States Of America, The | Monoclonal antibodies against chlamydial genes specific lipopolysaccharide |
| US4818687A (en) * | 1985-02-28 | 1989-04-04 | Massachusetts Institute Of Technology | Affinity column and process for detection of low molecular weight toxic substances |
| US4859611A (en) * | 1985-02-28 | 1989-08-22 | Massachusetts Institute Of Technology | Affinity column and process for detection of low molecular weight toxic substances |
| IL75828A (en) * | 1985-07-17 | 1991-06-10 | Univ Ramot | Immobilization by biologically active proteins |
| NZ218336A (en) * | 1985-12-09 | 1991-08-27 | Kirin Amgen Inc | Monoclonal antibodies to human pluripotent granulocyte colony stimulating factor (hpg-csf) |
| US5175255A (en) * | 1987-03-23 | 1992-12-29 | Amgen Inc. | Methods for purification of platelet-derived growth factor |
| US5190859A (en) * | 1987-02-26 | 1993-03-02 | Dana-Farber Cancer Institute, Inc. | Purification of LFA-3 |
| SE468653B (sv) * | 1987-03-06 | 1993-02-22 | Perstorp Biolytica | Adsorbent foer isokratisk affinitetskromatografi |
| JPS6463599A (en) * | 1987-05-01 | 1989-03-09 | Xoma Corp | Purification of immunoglobulin by selective anti-idiotype bond |
| DE3871799D1 (de) * | 1987-07-14 | 1992-07-09 | Univ Manchester | Verfahren zur diagnose von infektionen, bei welchem lipopolyscaccharidantigene bestimmt werden. |
| CA1323567C (en) * | 1987-10-05 | 1993-10-26 | Gene R. Nathans | Method for purification of antibodies |
| US5372812A (en) * | 1988-04-04 | 1994-12-13 | The General Hospital Corporation | Composition and method for acceleration of clot lysis |
| US5582862A (en) | 1988-04-04 | 1996-12-10 | General Hospital Corporation | Antibodies that bind to α2-antiplasmin crosslinked to fibrin which do not inhibit plasma α2-antiplasmin |
| JP2001515345A (ja) * | 1996-09-20 | 2001-09-18 | ザ・ジェネラル・ホスピタル・コーポレイション | アルファ―２―抗プラスミンに対する抗体を用いてフィブリン溶解を増進するための組成物と方法 |
| SG189775A1 (en) * | 2008-04-11 | 2013-05-31 | Chugai Pharmaceutical Co Ltd | Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly |
| CA2819356C (en) | 2010-11-30 | 2023-01-24 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly |
| EP3604330A1 (en) | 2011-02-25 | 2020-02-05 | Chugai Seiyaku Kabushiki Kaisha | Fcgammariib-specific fc antibody |
| EP2762493B1 (en) | 2011-09-30 | 2021-06-09 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule promoting disappearance of antigens having plurality of biological activities |
| SG11201402750SA (en) | 2011-11-30 | 2014-10-30 | Chugai Pharmaceutical Co Ltd | Drug containing carrier into cell for forming immune complex |
| JP6227191B1 (ja) | 2014-12-19 | 2017-11-08 | 中外製薬株式会社 | 抗ミオスタチン抗体、変異Ｆｃ領域を含むポリペプチド、および使用方法 |
| UA128712C2 (uk) | 2014-12-19 | 2024-10-09 | Чугаі Сейяку Кабусікі Кайся | Антитіла проти c5 та способи застосування |
| US11359009B2 (en) | 2015-12-25 | 2022-06-14 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies and methods of use |
| KR20250008966A (ko) | 2016-08-05 | 2025-01-16 | 추가이 세이야쿠 가부시키가이샤 | Il-8 관련 질환의 치료용 또는 예방용 조성물 |
| EP3574010A4 (en) | 2017-01-30 | 2020-12-16 | Chugai Seiyaku Kabushiki Kaisha | ANTI-SCLEROSTIN ANTIBODIES AND METHOD OF USE |
| CN110724204B (zh) * | 2019-11-18 | 2021-10-22 | 广东菲鹏制药股份有限公司 | Fc融合蛋白的纯化方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4172124A (en) * | 1978-04-28 | 1979-10-23 | The Wistar Institute | Method of producing tumor antibodies |
| ATE14269T1 (de) * | 1981-02-26 | 1985-08-15 | Unilever Nv | Verfahren und vorrichtung zur rueckgewinnung von immunoglobulinen. |
| US4474893A (en) * | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
| US4361509A (en) * | 1981-12-14 | 1982-11-30 | Scripps Clinic And Research Foundation | Ultrapurification of factor VIII using monoclonal antibodies |
-
1983
- 1983-04-11 ES ES521371A patent/ES521371A0/es active Granted
- 1983-04-11 CA CA000425555A patent/CA1209907A/en not_active Expired
- 1983-04-12 CH CH6699/83A patent/CH672028A5/de not_active IP Right Cessation
- 1983-04-12 IT IT20550/83A patent/IT1219779B/it active
- 1983-04-12 EP EP19830901671 patent/EP0105359A4/en not_active Withdrawn
- 1983-04-12 GB GB08332644A patent/GB2128630B/en not_active Expired
- 1983-04-12 AT AT9019/83A patent/AT393386B/de not_active IP Right Cessation
- 1983-04-12 WO PCT/US1983/000524 patent/WO1983003678A1/en not_active Application Discontinuation
- 1983-12-09 FI FI834530A patent/FI88403C/fi not_active IP Right Cessation
- 1983-12-13 ES ES528001A patent/ES8706964A1/es not_active Expired
- 1983-12-13 ES ES528000A patent/ES8506902A1/es not_active Expired
-
1987
- 1987-05-06 AU AU72569/87A patent/AU622099B2/en not_active Ceased
-
1991
- 1991-11-26 DK DK911921A patent/DK192191D0/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0105359A4 (en) | 1984-08-20 |
| ES8706964A1 (es) | 1987-07-01 |
| CA1209907A (en) | 1986-08-19 |
| IT1219779B (it) | 1990-05-24 |
| ES528000A0 (es) | 1985-08-01 |
| GB8332644D0 (en) | 1984-01-11 |
| ES8404858A1 (es) | 1984-05-16 |
| GB2128630A (en) | 1984-05-02 |
| WO1983003678A1 (en) | 1983-10-27 |
| EP0105359A1 (en) | 1984-04-18 |
| FI834530L (fi) | 1983-12-09 |
| ATA901983A (de) | 1991-03-15 |
| ES8506902A1 (es) | 1985-08-01 |
| GB2128630B (en) | 1986-08-28 |
| FI88403C (fi) | 1993-05-10 |
| IT8320550A0 (it) | 1983-04-12 |
| FI834530A0 (fi) | 1983-12-09 |
| CH672028A5 (enrdf_load_stackoverflow) | 1989-10-13 |
| AT393386B (de) | 1991-10-10 |
| AU7256987A (en) | 1987-09-03 |
| ES521371A0 (es) | 1984-05-16 |
| FI88403B (fi) | 1993-01-29 |
| ES528001A0 (es) | 1987-07-01 |
| DK192191A (da) | 1991-11-26 |
| DK192191D0 (da) | 1991-11-26 |
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