IT1219779B - Procedimento di purificazione per affinita' in cui si impiegano anticorpi monoclonali - Google Patents

Procedimento di purificazione per affinita' in cui si impiegano anticorpi monoclonali

Info

Publication number
IT1219779B
IT1219779B IT20550/83A IT2055083A IT1219779B IT 1219779 B IT1219779 B IT 1219779B IT 20550/83 A IT20550/83 A IT 20550/83A IT 2055083 A IT2055083 A IT 2055083A IT 1219779 B IT1219779 B IT 1219779B
Authority
IT
Italy
Prior art keywords
affinity
monoclonal antibodies
purifying process
purifying
monoclonal
Prior art date
Application number
IT20550/83A
Other languages
English (en)
Italian (it)
Other versions
IT8320550A0 (it
Inventor
Richard M Bartholomew
Daniel E Beidler
Gary S David
Original Assignee
Hybritech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybritech Inc filed Critical Hybritech Inc
Publication of IT8320550A0 publication Critical patent/IT8320550A0/it
Application granted granted Critical
Publication of IT1219779B publication Critical patent/IT1219779B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IT20550/83A 1982-04-12 1983-04-12 Procedimento di purificazione per affinita' in cui si impiegano anticorpi monoclonali IT1219779B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36778182A 1982-04-12 1982-04-12

Publications (2)

Publication Number Publication Date
IT8320550A0 IT8320550A0 (it) 1983-04-12
IT1219779B true IT1219779B (it) 1990-05-24

Family

ID=23448565

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20550/83A IT1219779B (it) 1982-04-12 1983-04-12 Procedimento di purificazione per affinita' in cui si impiegano anticorpi monoclonali

Country Status (11)

Country Link
EP (1) EP0105359A4 (enrdf_load_stackoverflow)
AT (1) AT393386B (enrdf_load_stackoverflow)
AU (1) AU622099B2 (enrdf_load_stackoverflow)
CA (1) CA1209907A (enrdf_load_stackoverflow)
CH (1) CH672028A5 (enrdf_load_stackoverflow)
DK (1) DK192191D0 (enrdf_load_stackoverflow)
ES (3) ES521371A0 (enrdf_load_stackoverflow)
FI (1) FI88403C (enrdf_load_stackoverflow)
GB (1) GB2128630B (enrdf_load_stackoverflow)
IT (1) IT1219779B (enrdf_load_stackoverflow)
WO (1) WO1983003678A1 (enrdf_load_stackoverflow)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8328918D0 (en) * 1983-10-28 1983-11-30 Unilever Plc Alkaline phosphatase
GB8331071D0 (en) * 1983-11-22 1983-12-29 Karayiannis P Assay for dna/rna
US4666865A (en) * 1984-01-13 1987-05-19 Centocor, Inc. Immunoassay for biologically active human interferon-gamma employing unique monoclonal antibodies
US4789631A (en) * 1984-02-17 1988-12-06 Synbiotics Corporation Immunoassay for anti-dirofilaria immitis antibody
GB8426468D0 (en) * 1984-10-19 1984-11-28 Technology Licence Co Ltd Monoclonal antibodies
AU5259786A (en) * 1985-01-30 1986-08-07 United States Of America, The Monoclonal antibodies against chlamydial genes specific lipopolysaccharide
US4818687A (en) * 1985-02-28 1989-04-04 Massachusetts Institute Of Technology Affinity column and process for detection of low molecular weight toxic substances
US4859611A (en) * 1985-02-28 1989-08-22 Massachusetts Institute Of Technology Affinity column and process for detection of low molecular weight toxic substances
IL75828A (en) * 1985-07-17 1991-06-10 Univ Ramot Immobilization by biologically active proteins
NZ218336A (en) * 1985-12-09 1991-08-27 Kirin Amgen Inc Monoclonal antibodies to human pluripotent granulocyte colony stimulating factor (hpg-csf)
US5175255A (en) * 1987-03-23 1992-12-29 Amgen Inc. Methods for purification of platelet-derived growth factor
US5190859A (en) * 1987-02-26 1993-03-02 Dana-Farber Cancer Institute, Inc. Purification of LFA-3
SE468653B (sv) * 1987-03-06 1993-02-22 Perstorp Biolytica Adsorbent foer isokratisk affinitetskromatografi
JPS6463599A (en) * 1987-05-01 1989-03-09 Xoma Corp Purification of immunoglobulin by selective anti-idiotype bond
DE3871799D1 (de) * 1987-07-14 1992-07-09 Univ Manchester Verfahren zur diagnose von infektionen, bei welchem lipopolyscaccharidantigene bestimmt werden.
CA1323567C (en) * 1987-10-05 1993-10-26 Gene R. Nathans Method for purification of antibodies
US5372812A (en) * 1988-04-04 1994-12-13 The General Hospital Corporation Composition and method for acceleration of clot lysis
US5582862A (en) 1988-04-04 1996-12-10 General Hospital Corporation Antibodies that bind to α2-antiplasmin crosslinked to fibrin which do not inhibit plasma α2-antiplasmin
JP2001515345A (ja) * 1996-09-20 2001-09-18 ザ・ジェネラル・ホスピタル・コーポレイション アルファ―２―抗プラスミンに対する抗体を用いてフィブリン溶解を増進するための組成物と方法
SG189775A1 (en) * 2008-04-11 2013-05-31 Chugai Pharmaceutical Co Ltd Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
CA2819356C (en) 2010-11-30 2023-01-24 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly
EP3604330A1 (en) 2011-02-25 2020-02-05 Chugai Seiyaku Kabushiki Kaisha Fcgammariib-specific fc antibody
EP2762493B1 (en) 2011-09-30 2021-06-09 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule promoting disappearance of antigens having plurality of biological activities
SG11201402750SA (en) 2011-11-30 2014-10-30 Chugai Pharmaceutical Co Ltd Drug containing carrier into cell for forming immune complex
JP6227191B1 (ja) 2014-12-19 2017-11-08 中外製薬株式会社 抗ミオスタチン抗体、変異Ｆｃ領域を含むポリペプチド、および使用方法
UA128712C2 (uk) 2014-12-19 2024-10-09 Чугаі Сейяку Кабусікі Кайся Антитіла проти c5 та способи застосування
US11359009B2 (en) 2015-12-25 2022-06-14 Chugai Seiyaku Kabushiki Kaisha Anti-myostatin antibodies and methods of use
KR20250008966A (ko) 2016-08-05 2025-01-16 추가이 세이야쿠 가부시키가이샤 Il-8 관련 질환의 치료용 또는 예방용 조성물
EP3574010A4 (en) 2017-01-30 2020-12-16 Chugai Seiyaku Kabushiki Kaisha ANTI-SCLEROSTIN ANTIBODIES AND METHOD OF USE
CN110724204B (zh) * 2019-11-18 2021-10-22 广东菲鹏制药股份有限公司 Fc融合蛋白的纯化方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172124A (en) * 1978-04-28 1979-10-23 The Wistar Institute Method of producing tumor antibodies
ATE14269T1 (de) * 1981-02-26 1985-08-15 Unilever Nv Verfahren und vorrichtung zur rueckgewinnung von immunoglobulinen.
US4474893A (en) * 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
US4361509A (en) * 1981-12-14 1982-11-30 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies

Also Published As

Publication number Publication date
EP0105359A4 (en) 1984-08-20
ES8706964A1 (es) 1987-07-01
CA1209907A (en) 1986-08-19
ES528000A0 (es) 1985-08-01
GB8332644D0 (en) 1984-01-11
ES8404858A1 (es) 1984-05-16
GB2128630A (en) 1984-05-02
WO1983003678A1 (en) 1983-10-27
EP0105359A1 (en) 1984-04-18
FI834530L (fi) 1983-12-09
ATA901983A (de) 1991-03-15
ES8506902A1 (es) 1985-08-01
GB2128630B (en) 1986-08-28
FI88403C (fi) 1993-05-10
IT8320550A0 (it) 1983-04-12
FI834530A0 (fi) 1983-12-09
CH672028A5 (enrdf_load_stackoverflow) 1989-10-13
AT393386B (de) 1991-10-10
AU622099B2 (en) 1992-04-02
AU7256987A (en) 1987-09-03
ES521371A0 (es) 1984-05-16
FI88403B (fi) 1993-01-29
ES528001A0 (es) 1987-07-01
DK192191A (da) 1991-11-26
DK192191D0 (da) 1991-11-26

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