AU600782B2 - New alkanesulfonanilide and alkylaminosulfonanilide derivatives, processes for their preparation and pharmaceutical compositions comprising the same - Google Patents

New alkanesulfonanilide and alkylaminosulfonanilide derivatives, processes for their preparation and pharmaceutical compositions comprising the same Download PDF

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Publication number
AU600782B2
AU600782B2 AU83152/87A AU8315287A AU600782B2 AU 600782 B2 AU600782 B2 AU 600782B2 AU 83152/87 A AU83152/87 A AU 83152/87A AU 8315287 A AU8315287 A AU 8315287A AU 600782 B2 AU600782 B2 AU 600782B2
Authority
AU
Australia
Prior art keywords
hydrogen
compound
difluorophenoxy
mixture
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU83152/87A
Other languages
English (en)
Other versions
AU8315287A (en
Inventor
Nobukiyo Konishi
Masaaki Matsuo
Kiyoshi Tsuji
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868631083A external-priority patent/GB8631083D0/en
Priority claimed from GB878712647A external-priority patent/GB8712647D0/en
Priority claimed from GB878724903A external-priority patent/GB8724903D0/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of AU8315287A publication Critical patent/AU8315287A/en
Application granted granted Critical
Publication of AU600782B2 publication Critical patent/AU600782B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
    • C07D213/20—Quaternary compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C07D271/07—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/40—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU83152/87A 1986-12-31 1987-12-30 New alkanesulfonanilide and alkylaminosulfonanilide derivatives, processes for their preparation and pharmaceutical compositions comprising the same Ceased AU600782B2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB868631083A GB8631083D0 (en) 1986-12-31 1986-12-31 2'-phenoxyalkanesulfonanilide derivatives
GB8631083 1986-12-31
GB878712647A GB8712647D0 (en) 1987-05-29 1987-05-29 2'-phenoxyalkanesulfonanilide derivatives
GB8712647 1987-05-29
GB8724903 1987-10-23
GB878724903A GB8724903D0 (en) 1987-10-23 1987-10-23 2-phenoxyalkanesulfonanilide derivatives

Publications (2)

Publication Number Publication Date
AU8315287A AU8315287A (en) 1988-07-07
AU600782B2 true AU600782B2 (en) 1990-08-23

Family

ID=27263273

Family Applications (1)

Application Number Title Priority Date Filing Date
AU83152/87A Ceased AU600782B2 (en) 1986-12-31 1987-12-30 New alkanesulfonanilide and alkylaminosulfonanilide derivatives, processes for their preparation and pharmaceutical compositions comprising the same

Country Status (15)

Country Link
US (1) US4866091A (enExample)
EP (1) EP0273369B1 (enExample)
KR (1) KR910008138B1 (enExample)
CN (1) CN87108295A (enExample)
AR (1) AR243499A1 (enExample)
AU (1) AU600782B2 (enExample)
DE (1) DE3777122D1 (enExample)
DK (1) DK693587A (enExample)
ES (1) ES2033292T3 (enExample)
FI (1) FI875719A7 (enExample)
GR (1) GR3004051T3 (enExample)
HU (1) HU200322B (enExample)
IL (1) IL84913A0 (enExample)
NO (1) NO168299C (enExample)
PT (1) PT86407B (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL86462A (en) * 1987-05-29 1992-12-01 Fujisawa Pharmaceutical Co Alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical compositions comprising the same
JPH0753725B2 (ja) * 1987-10-08 1995-06-07 富山化学工業株式会社 ４ｈ―１―ベンゾピラン―４―オン誘導体およびその塩、それらの製造法並びにそれらを含有する抗炎症剤
FI911633A7 (fi) * 1990-04-27 1991-10-28 Fujisawa Pharmaceutical Co Menetelmä alkaanisulfoanilidijohdosten valmistamiseksi
CA2115242A1 (en) * 1991-08-08 1993-02-18 Kensei Yoshikawa 5-aminosulfonanilide compounds
US5449826A (en) * 1992-06-12 1995-09-12 Taisho Pharmaceutical Co., Ltd. 5-amino-2-phenoxysulfonanilide compound
US5604260A (en) * 1992-12-11 1997-02-18 Merck Frosst Canada Inc. 5-methanesulfonamido-1-indanones as an inhibitor of cyclooxygenase-2
WO1996023786A1 (en) * 1995-01-31 1996-08-08 Merck Frosst Canada Inc. 5-methanesulfonamido-3h-isobenzofuran-1-ones as inhibitors of cyclooxygenase-2
US5681842A (en) * 1996-11-08 1997-10-28 Abbott Laboratories Prostaglandin synthase-2 inhibitors
ATE289295T1 (de) * 1997-04-22 2005-03-15 Euro Celtique Sa Die verwendung von durch carbozyklische und heterozyklische reste substituierte semicarbazonen und thiosemicarbazonen als natriumkanalblocker
ES2158809B1 (es) * 1999-10-18 2002-03-16 Menarini Lab Nuevos derivados sulfonados como inhibidores de la ciclooxigenasa ii.
EP1635800A2 (en) * 2003-06-10 2006-03-22 Kalypsys, Inc. Carbonyl compounds as inhibitors of histone deacetylase for the treatment of disease
US7470722B2 (en) 2004-06-10 2008-12-30 Kalypsys, Inc. Multicyclic sulfonamide compounds as inhibitors of histone deacetylase for the treatment of disease
EP2493852B1 (en) * 2009-10-30 2014-04-09 Janssen Pharmaceutica NV 4-substituted-2-phenoxy-phenylamine delta opioid receptor modulators
JP6484555B2 (ja) * 2013-08-29 2019-03-13 京都薬品工業株式会社 新規芳香族化合物およびその用途
CN109912434B (zh) * 2017-12-13 2022-07-12 上海安谱实验科技股份有限公司 苯乙醇胺类β受体激动剂的合成方法
CN109608370A (zh) * 2019-01-22 2019-04-12 山西康斯亚森生物科技有限公司 尼美舒利衍生物和制备方法及用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3531523A (en) * 1967-07-18 1970-09-29 Upjohn Co N-(phenoxyphenyl)sulfamides
US3531522A (en) * 1967-07-18 1970-09-29 Upjohn Co 4'-phenoxyalkanesulfonanilides
US3840597A (en) * 1971-02-24 1974-10-08 Riker Laboratories Inc Substituted 2-phenoxy alkane-sulfonanilides
US3906024A (en) * 1971-02-24 1975-09-16 Minnesota Mining & Mfg Perfluoroalkanesulfonamidoaryl compounds
AR206496A1 (es) * 1972-07-03 1976-07-30 Riker Laboratories Inc Procedimiento para la preparacion de 2-fenoxi-4-nitro-alquil o haloalquilsulfonanilidas
US4465508A (en) * 1979-07-18 1984-08-14 Imperial Chemical Industries Plc Diphenyl ether herbicides
DE3114072A1 (de) * 1981-04-08 1982-11-04 Basf Ag, 6700 Ludwigshafen Herbizide diphenylether, deren herstellung und verwendung als herbizide
EP0149423B1 (de) * 1983-12-16 1987-10-28 Ciba-Geigy Ag Verfahren zum Schützen von Keratinmaterial vor dem Befall durch keratinfressende Insekten und neue Phenoxytrifluormethansulfonanilide

Also Published As

Publication number Publication date
NO168299C (no) 1992-02-05
AU8315287A (en) 1988-07-07
CN87108295A (zh) 1988-07-13
GR3004051T3 (enExample) 1993-03-31
DK693587A (da) 1988-07-01
AR243499A1 (es) 1993-08-31
KR880007447A (ko) 1988-08-27
IL84913A0 (en) 1988-06-30
HUT45971A (en) 1988-09-28
HU200322B (en) 1990-05-28
NO875488D0 (no) 1987-12-30
DK693587D0 (da) 1987-12-30
ES2033292T3 (es) 1993-03-16
DE3777122D1 (de) 1992-04-09
NO875488L (no) 1988-07-01
US4866091A (en) 1989-09-12
EP0273369B1 (en) 1992-03-04
EP0273369A2 (en) 1988-07-06
FI875719A0 (fi) 1987-12-28
NO168299B (no) 1991-10-28
EP0273369A3 (en) 1989-10-18
PT86407A (en) 1988-01-01
PT86407B (pt) 1990-11-20
KR910008138B1 (ko) 1991-10-10
FI875719L (fi) 1988-07-01
FI875719A7 (fi) 1988-07-01

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