AU520078B2 - Collagen drug delivery device - Google Patents

Collagen drug delivery device

Info

Publication number
AU520078B2
AU520078B2 AU40000/78A AU4000078A AU520078B2 AU 520078 B2 AU520078 B2 AU 520078B2 AU 40000/78 A AU40000/78 A AU 40000/78A AU 4000078 A AU4000078 A AU 4000078A AU 520078 B2 AU520078 B2 AU 520078B2
Authority
AU
Australia
Prior art keywords
delivery device
drug delivery
collagen drug
collagen
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU40000/78A
Other languages
English (en)
Other versions
AU4000078A (en
Inventor
A L Rubin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PIKOK INTERNATIONAL TRADING CO Ltd
Original Assignee
PIKOK IND TRADING CO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PIKOK IND TRADING CO filed Critical PIKOK IND TRADING CO
Publication of AU4000078A publication Critical patent/AU4000078A/en
Application granted granted Critical
Publication of AU520078B2 publication Critical patent/AU520078B2/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
AU40000/78A 1977-09-21 1978-09-20 Collagen drug delivery device Expired AU520078B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/835,302 US4164559A (en) 1977-09-21 1977-09-21 Collagen drug delivery device

Publications (2)

Publication Number Publication Date
AU4000078A AU4000078A (en) 1980-03-27
AU520078B2 true AU520078B2 (en) 1982-01-14

Family

ID=25269163

Family Applications (1)

Application Number Title Priority Date Filing Date
AU40000/78A Expired AU520078B2 (en) 1977-09-21 1978-09-20 Collagen drug delivery device

Country Status (6)

Country Link
US (1) US4164559A (OSRAM)
JP (1) JPS5446817A (OSRAM)
AU (1) AU520078B2 (OSRAM)
GB (1) GB1594805A (OSRAM)
NZ (1) NZ188435A (OSRAM)
PH (1) PH13977A (OSRAM)

Families Citing this family (205)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2843963A1 (de) * 1978-10-09 1980-04-24 Merck Patent Gmbh Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin
US4374121A (en) * 1979-09-12 1983-02-15 Seton Company Macromolecular biologically active collagen articles
JPS5767521A (en) * 1980-09-25 1982-04-24 Yamanouchi Pharmaceut Co Ltd Agent for improving circulation blood vessel
US4304765A (en) * 1980-10-14 1981-12-08 Alza Corporation Ocular insert housing steroid in two different therapeutic forms
US4432964A (en) * 1981-08-24 1984-02-21 Alza Corporation Topical composition containing steroid in two forms released independently from polymeric carrier
FR2524312B1 (fr) * 1982-04-01 1985-10-04 Tech Cuir Centre Nouvelles formes de micro-encapsulation de substances medicamenteuses par des couches homogenes de collagene natif
US4505855A (en) * 1982-09-30 1985-03-19 Massachusetts General Hospital Transparent non-fibrilized collagen material by ultracentrifugation
US4478818A (en) * 1982-12-27 1984-10-23 Alza Corporation Ocular preparation housing steroid in two different therapeutic forms
GB8306353D0 (en) * 1983-03-08 1983-04-13 Stuart J F B Monitoring of drug levels
JPS6025920A (ja) * 1983-07-22 1985-02-08 Japan Atom Energy Res Inst 薬物含有徐放性複合体及びその調製方法
JPS6028936A (ja) * 1983-07-27 1985-02-14 Koken:Kk アテロコラ−ゲン水溶液およびその製造方法
JPS6089418A (ja) * 1983-10-20 1985-05-20 Sumitomo Chem Co Ltd 徐放性制癌剤
JPS6084213A (ja) * 1983-10-14 1985-05-13 Sumitomo Chem Co Ltd 徐放性消炎鎮痛製剤
US4563184A (en) * 1983-10-17 1986-01-07 Bernard Korol Synthetic resin wound dressing and method of treatment using same
FR2559780B1 (fr) * 1984-02-21 1990-05-04 Tech Cuir Centre Systemes biocompatibles implantables a base de collagene permettant la conservation et/ou la culture cellulaires et/ou la liberation controlee de principes actifs
US4748152A (en) * 1985-01-22 1988-05-31 Opticol Corp. Succinylated atelocollagen solution for use in viscosurgery and as a vitreous substitute
US4851513A (en) * 1985-09-06 1989-07-25 Minnesota Mining And Manufacturing Company Viscoelastic collagen solution for opthalmic use and method of preparation
US4883864A (en) * 1985-09-06 1989-11-28 Minnesota Mining And Manufacturing Company Modified collagen compound and method of preparation
US4713446A (en) * 1985-09-06 1987-12-15 Minnesota Mining And Manufacturing Company Viscoelastic collagen solution for ophthalmic use and method of preparation
DE3688188T2 (de) * 1985-12-27 1993-10-14 Koken Kk Verfahren zur Herstellung einer Formulierung mit verzögerter Freisetzung.
FR2601371B1 (fr) * 1986-07-11 1989-05-12 Merieux Inst Procede de traitement du collagene en vue, notamment, d'en faciliter la reticulation et collagene obtenu par application dudit procede
US5128134A (en) * 1986-09-17 1992-07-07 Fyodorov Svyatoslav N Ophthalmological collagen coverings
US5989579A (en) * 1986-10-02 1999-11-23 Escalon Medical Corp. Ocular insert with anchoring protrusions
US5147647A (en) * 1986-10-02 1992-09-15 Sohrab Darougar Ocular insert for the fornix
US5322691A (en) * 1986-10-02 1994-06-21 Sohrab Darougar Ocular insert with anchoring protrusions
US5094855A (en) * 1986-10-13 1992-03-10 Moskovsky Nauchno-Teknichesky Compleks "Mikrochirurgija Glaza" Opthalmological collagen coverings
ES2058351T3 (es) * 1988-01-29 1994-11-01 Sumitomo Pharma Un procedimiento para producir una formulacion de liberacion sostenida que es adecuada para el uso humano y veterinario.
US4969912A (en) * 1988-02-18 1990-11-13 Kelman Charles D Human collagen processing and autoimplant use
WO1989008465A1 (fr) * 1988-03-09 1989-09-21 Terumo Kabushiki Kaisha Substance medicale dans laquelle les cellules peuvent penetrer et peau artificielle
US4882150A (en) * 1988-06-03 1989-11-21 Kaufman Herbert E Drug delivery system
US4923699A (en) * 1988-06-03 1990-05-08 Kaufman Herbert E Eye treatment suspension
US4865846A (en) * 1988-06-03 1989-09-12 Kaufman Herbert E Drug delivery system
US4923700A (en) * 1988-06-03 1990-05-08 Kaufman Herbert E Artificial tear suspension
US5565519A (en) * 1988-11-21 1996-10-15 Collagen Corporation Clear, chemically modified collagen-synthetic polymer conjugates for ophthalmic applications
US5936035A (en) * 1988-11-21 1999-08-10 Cohesion Technologies, Inc. Biocompatible adhesive compositions
US5475052A (en) * 1988-11-21 1995-12-12 Collagen Corporation Collagen-synthetic polymer matrices prepared using a multiple step reaction
US5800541A (en) * 1988-11-21 1998-09-01 Collagen Corporation Collagen-synthetic polymer matrices prepared using a multiple step reaction
US4946450A (en) * 1989-04-18 1990-08-07 Biosource Genetics Corporation Glucan/collagen therapeutic eye shields
US4978352A (en) * 1989-06-07 1990-12-18 Fedorov Svjatoslav N Process for producing collagen-based cross-linked biopolymer, an implant from said biopolymer, method for producing said implant, and method for hermetization of corneal or scleral wounds involved in eye injuries, using said implant
US5138030A (en) * 1989-10-10 1992-08-11 Pachence James M Process for extracting type I collagen form an avian source, and applications therefor
JPH03121203U (OSRAM) * 1990-03-27 1991-12-12
US5103840A (en) * 1990-05-07 1992-04-14 Kavoussi Harold P Viscoelastic collagen gel for ophthalmic surgery
US5322648A (en) * 1991-08-26 1994-06-21 Vitaphore Corporation Process for forming shaped collagen devices
US5259998A (en) * 1991-10-04 1993-11-09 Chiron Ophthalmics, Inc. Method for casting dissolvable ophthalmic shields in a mold
CA2140053C (en) * 1994-02-09 2000-04-04 Joel S. Rosenblatt Collagen-based injectable drug delivery system and its use
US5466233A (en) * 1994-04-25 1995-11-14 Escalon Ophthalmics, Inc. Tack for intraocular drug delivery and method for inserting and removing same
DE4414755C2 (de) * 1994-04-27 2000-11-16 Lohmann Therapie Syst Lts Kollagenzubereitung zur gesteuerten Abgabe von Wirkstoffen, Verfahren und Verwendung
US5928667A (en) * 1994-06-24 1999-07-27 University Of Maryland Drug delivery device and method for employing the same
EP0713707A1 (en) * 1994-11-23 1996-05-29 Collagen Corporation In situ crosslinkable, injectable collagen composition for tissue augmention
US5518732A (en) * 1995-02-14 1996-05-21 Chiron Vision, Inc. Bio-erodible ophthalmic shield
JPH11501512A (ja) * 1995-03-03 1999-02-09 メタボレックス，インコーポレイティド ゲル化ポリマーによる新規の被包方法
US5916790A (en) * 1995-03-03 1999-06-29 Metabolex, Inc. Encapsulation compositions, and methods
DE19549506C2 (de) * 1995-03-07 1998-07-30 Richard Prof Dr Sueverkruep Darreichungsform zur äußerlichen Applikation und Verfahren zur Herstellung derselben
US6962979B1 (en) 1995-03-14 2005-11-08 Cohesion Technologies, Inc. Crosslinkable biomaterial compositions containing hydrophobic and hydrophilic crosslinking agents
US5788959A (en) * 1995-04-24 1998-08-04 University Of Maryland, Baltimore County Drug delivery device and method for employing the same
US5677284A (en) * 1995-06-06 1997-10-14 Regen Biologics, Inc. Charged collagen particle-based delivery matrix
EP2111876B1 (en) 1995-12-18 2011-09-07 AngioDevice International GmbH Crosslinked polymer compositions and methods for their use
US6458889B1 (en) 1995-12-18 2002-10-01 Cohesion Technologies, Inc. Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
US7883693B2 (en) 1995-12-18 2011-02-08 Angiodevice International Gmbh Compositions and systems for forming crosslinked biomaterials and methods of preparation of use
US6833408B2 (en) 1995-12-18 2004-12-21 Cohesion Technologies, Inc. Methods for tissue repair using adhesive materials
HUP9901821A2 (hu) * 1996-01-05 1999-09-28 Autoimmune, Inc. Eljárás II-es típusú kollagén előállítására
US6299895B1 (en) 1997-03-24 2001-10-09 Neurotech S.A. Device and method for treating ophthalmic diseases
US7435425B2 (en) * 2001-07-17 2008-10-14 Baxter International, Inc. Dry hemostatic compositions and methods for their preparation
US8303981B2 (en) 1996-08-27 2012-11-06 Baxter International Inc. Fragmented polymeric compositions and methods for their use
US6066325A (en) 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US8603511B2 (en) 1996-08-27 2013-12-10 Baxter International, Inc. Fragmented polymeric compositions and methods for their use
US6083522A (en) * 1997-01-09 2000-07-04 Neucoll, Inc. Devices for tissue repair and methods for preparation and use thereof
JPH1156897A (ja) * 1997-08-18 1999-03-02 Koken Co Ltd コラーゲン眼科手術補助剤
US6197934B1 (en) 1998-05-22 2001-03-06 Collagenesis, Inc. Compound delivery using rapidly dissolving collagen film
DE60027576T2 (de) * 1999-08-17 2007-05-03 Luminex Corp., Austin Verkapselung von fluoreszierenden partikeln
ES2383122T3 (es) 1999-08-27 2012-06-18 Angiodevice International Gmbh Dispositivo de polímero biocompatible
ES2621652T3 (es) 2001-01-16 2017-07-04 Vascular Therapies, Inc. Dispositivo implantable que contiene material de matriz reabsorbible y rapamicina para evitar o tratar enfermedades vasculoproliferativas
EP1404297B1 (en) 2001-06-12 2011-04-27 The Johns Hopkins University School Of Medicine Reservoir device for intraocular drug delivery
US20030181371A1 (en) * 2001-12-28 2003-09-25 Angiotech Pharmaceuticals, Inc. Compositions and methods of using collajolie
US20070225631A1 (en) * 2002-10-04 2007-09-27 Bowlin Gary L Sealants for Skin and Other Tissues
US20050013845A1 (en) * 2002-11-12 2005-01-20 Warren Stephen L. Adhesive bioerodible ocular drug delivery system
WO2004060346A2 (en) 2002-12-30 2004-07-22 Angiotech International Ag Drug delivery from rapid gelling polymer composition
EP1583561A3 (en) * 2002-12-30 2005-12-07 Angiotech International Ag Tissue reactive compounds and compositions and uses thereof
US8834864B2 (en) * 2003-06-05 2014-09-16 Baxter International Inc. Methods for repairing and regenerating human dura mater
PL1638624T3 (pl) 2003-06-19 2014-06-30 Vascular Therapies Llc Wyrób do zamykania naczyń krwionośnych
US7927626B2 (en) * 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
CA2536454C (en) 2003-08-26 2013-03-26 Vista Scientific Ocular drug delivery device
BRPI0510477B1 (pt) 2004-04-28 2023-01-17 Angiotech Biomaterials Corporation Método para formar um gel e dispositivo para uso em aplicações médicas
US8303973B2 (en) 2004-09-17 2012-11-06 Angiotech Pharmaceuticals (Us), Inc. Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use
WO2006041942A2 (en) * 2004-10-04 2006-04-20 Qlt Usa, Inc. Ocular delivery of polymeric delivery formulations
US8313763B2 (en) * 2004-10-04 2012-11-20 Tolmar Therapeutics, Inc. Sustained delivery formulations of rapamycin compounds
EP1861104A4 (en) * 2005-03-04 2011-12-14 Neurosystec Corp IMPROVED GACYCLIDINE FORMULATIONS
WO2006113845A1 (en) * 2005-04-19 2006-10-26 Therabit, Inc. Implantable tissue-reactive biomaterial compositions and systems, and methods of use thereof
US20060247776A1 (en) * 2005-05-02 2006-11-02 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for augmenting intervertebral discs
US20070005140A1 (en) * 2005-06-29 2007-01-04 Kim Daniel H Fabrication and use of biocompatible materials for treating and repairing herniated spinal discs
US20070233252A1 (en) * 2006-02-23 2007-10-04 Kim Daniel H Devices, systems and methods for treating intervertebral discs
KR20090006153A (ko) 2006-03-31 2009-01-14 큐엘티 플러그 딜리버리, 인코포레이티드 비루관계에 대한 약물 전달 방법, 구조, 및 조성물
BRPI0712088B8 (pt) * 2006-05-31 2021-06-22 Baxter Healthcare Sa uso de uma biomatriz de lâmina de colágeno de múltiplas camadas microscópicas não porosa e hermética a fluido
US7803148B2 (en) * 2006-06-09 2010-09-28 Neurosystec Corporation Flow-induced delivery from a drug mass
TWI436793B (zh) 2006-08-02 2014-05-11 Baxter Int 快速作用之乾密封膠及其使用和製造方法
WO2008035376A2 (en) * 2006-09-19 2008-03-27 Council Of Scientific & Industrial Research A novel bio-erodible insert for ophthalmic applications and a process for the preparation thereof
US20090054984A1 (en) 2007-08-20 2009-02-26 Histogenics Corporation Method For Use Of A Double-Structured Tissue Implant For Treatment Of Tissue Defects
US8685107B2 (en) 2007-07-03 2014-04-01 Histogenics Corporation Double-structured tissue implant and a method for preparation and use thereof
CL2008003219A1 (es) 2007-10-30 2009-10-09 Baxter Int Uso de una biomatriz de colageno biofuncional, multicapas y no porosa, que dirige el crecimiento celular dentro de los intersticios de la biomatriz de colageno, para tratar un defecto de una membrana visceral o parietal; y biomatriz utilizada.
EP2238163A1 (en) * 2008-01-31 2010-10-13 Sofradim Production Preparation of terminally-sterilized collagen that is soluble at neutral ph
EP2259803B2 (en) 2008-02-29 2019-03-13 Ferrosan Medical Devices A/S Device for promotion of hemostasis and/or wound healing
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
SG2014007389A (en) 2009-01-29 2014-04-28 Forsight Vision4 Inc Posterior segment drug delivery
US20100226962A1 (en) * 2009-03-03 2010-09-09 Rodstrom Theron R Peri-corneal drug delivery device
US9039783B2 (en) * 2009-05-18 2015-05-26 Baxter International, Inc. Method for the improvement of mesh implant biocompatibility
EP2442835B1 (en) * 2009-06-16 2014-12-10 Baxter International Inc Hemostatic sponge
EP2987487B1 (en) 2009-08-10 2020-10-07 Samumed, LLC Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof
NZ599399A (en) * 2009-10-07 2014-05-30 Kerecis Ehf A scaffold material for wound care and/or other tissue healing applications
CA2776748A1 (en) * 2009-10-08 2011-04-14 Neurotech Usa, Inc. Use of pedf in an encapsulated cell-based delivery system
CA2784432C (en) 2009-12-16 2019-01-15 Baxter Healthcare S.A. Hemostatic sponge
PL3001903T3 (pl) 2009-12-21 2018-03-30 Samumed, Llc 1H-pirazolo[3,4-b]pirydyny i ich zastosowania terapeutyczne
US8469934B2 (en) * 2010-01-27 2013-06-25 Alcon Research, Ltd. Pulsatile peri-corneal drug delivery device
WO2013022801A1 (en) 2011-08-05 2013-02-14 Forsight Vision4, Inc. Small molecule delivery with implantable therapeutic device
SA111320355B1 (ar) 2010-04-07 2015-01-08 Baxter Heathcare S A إسفنجة لايقاف النزف
KR101957625B1 (ko) 2010-06-01 2019-03-12 백스터 인터내셔널 인코포레이티드 건조 및 안정한 지혈 조성물의 제조 방법
JP5973997B2 (ja) 2010-06-01 2016-08-23 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ 乾燥した安定な止血用組成物を作製するためのプロセス
BR112012030457B1 (pt) 2010-06-01 2021-03-09 Baxter International Inc. processo para fabricar uma composição hemostática seca e estável, recipiente acabado final, método para prover uma composição hemostática pronta para uso, e, kit para administrar uma composição hemostática
AU2011285964A1 (en) * 2010-08-02 2013-02-28 Euclid Systems Corporation Collagen-based implants for sustained delivery of drugs
US9033911B2 (en) 2010-08-05 2015-05-19 Forsight Vision4, Inc. Injector apparatus and method for drug delivery
CA2807537C (en) 2010-08-05 2018-09-18 Forsight Vision4, Inc. Combined drug delivery methods and apparatus
HRP20211909T1 (hr) 2010-08-05 2022-03-18 Forsight Vision4, Inc. Uređaj za liječenja oka
PT3311666T (pt) 2010-08-18 2021-06-21 Biosplice Therapeutics Inc Dicetonas e hidroxicetonas como ativadores da via de sinalização de catenina
US20140031769A1 (en) 2010-11-19 2014-01-30 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
CN103492016A (zh) 2010-11-23 2014-01-01 普莱萨格生命科学公司 用于实体递送的治疗方法和组合物
EP4249059B1 (en) 2011-06-28 2025-07-30 ForSight Vision4, Inc. An apparatus for collecting a sample of fluid from a reservoir chamber of a therapeutic device for the eye
WO2013040238A2 (en) 2011-09-13 2013-03-21 Vista Scientific Llc Sustained release ocular drug delivery devices and methods of manufacture
DK2755483T3 (en) 2011-09-14 2019-03-11 Samumed Llc INDAZOL-3-CARBOXAMIDES AND ITS USE AS WNT / B-CATENIN SIGNAL INHIBITORS
EP4643921A3 (en) 2011-09-16 2026-01-07 ForSight Vision4, Inc. Fluid exchange apparatus
JP6195569B2 (ja) 2011-10-11 2017-09-13 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ 止血組成物
KR102135484B1 (ko) 2011-10-11 2020-07-20 백스터 인터내셔널 인코포레이티드 지혈 조성물
AR088531A1 (es) 2011-10-27 2014-06-18 Baxter Int Composiciones hemostaticas
WO2013063530A2 (en) 2011-10-28 2013-05-02 Presage Biosciences, Inc. Methods for drug delivery
US11109849B2 (en) 2012-03-06 2021-09-07 Ferrosan Medical Devices A/S Pressurized container containing haemostatic paste
PH12017500997A1 (en) 2012-04-04 2018-02-19 Samumed Llc Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof
CN104271133B (zh) 2012-05-04 2017-10-13 萨穆梅德有限公司 1H‑吡唑并[3,4‑b]吡啶及其治疗应用
RU2636240C2 (ru) 2012-06-12 2017-11-21 Ферросан Медикал Дивайсиз А/С Сухая гемостатическая композиция
WO2014110086A2 (en) 2013-01-08 2014-07-17 Samumed, Llc 3-(benzoimidazol-2-yl)-indazole inhibitors of the wnt signaling pathway and therapeutic uses thereof
JP6401189B2 (ja) 2013-02-22 2018-10-03 サミュメッド リミテッド ライアビリティ カンパニー Ｗｎｔ／β−カテニンシグナル伝達経路活性化剤としてのγ−ジケトン
AU2014236455B2 (en) 2013-03-14 2018-07-12 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
WO2014160884A1 (en) 2013-03-28 2014-10-02 Forsight Vision4, Inc. Ophthalmic implant for delivering therapeutic substances
EP3010419B1 (en) 2013-06-21 2020-05-20 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
CN105828844B (zh) 2013-12-11 2019-09-27 弗罗桑医疗设备公司 包含挤出增强剂的干组合物
SG10201914111XA (en) 2014-03-20 2020-03-30 Samumed Llc 5-substituted indazole-3-carboxamides and preparation and use thereof
JP2017524034A (ja) 2014-08-08 2017-08-24 フォーサイト・ビジョン フォー・インコーポレーテッドＦｏｒｓｉｇｈｔ Ｖｉｓｉｏｎ４， Ｉｎｃ． 受容体型チロシンキナーゼ阻害剤の安定で可溶な製剤およびその調製の方法
MX368248B (es) 2014-08-20 2019-09-25 Samumed Llc Gamma-dicetonas para tratamiento y prevencion de piel envejecida y arrugas.
WO2016040180A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
WO2016040182A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 2-(1h-indazol-3-yl)-1h-imidazo[4,5-c]pyridine and therapeutic uses thereof
WO2016040190A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof
WO2016040184A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
WO2016040193A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof
WO2016040188A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(3h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
WO2016040185A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 2-(1h-indazol-3-yl)-3h-imidazo[4,5-b]pyridine and therapeutic uses thereof
WO2016040181A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
AU2015333206B2 (en) 2014-10-13 2019-07-11 Ferrosan Medical Devices A/S. Dry composition for use in haemostasis and wound healing
KR20170106298A (ko) 2014-11-10 2017-09-20 포사이트 비젼4, 인크. 확장 가능한 약물 전달 장치 및 이용 방법
AU2015371184B2 (en) 2014-12-24 2020-06-25 Ferrosan Medical Devices A/S Syringe for retaining and mixing first and second substances
WO2016187426A1 (en) 2015-05-19 2016-11-24 Amorphex Therapeutics Llc A device that delivers a sustained low-dose of a myopia-suppressing drug
WO2017005590A1 (en) 2015-07-03 2017-01-12 Ferrosan Medical Devices A/S Syringe for mixing two components and for retaining a vacuum in a storage condition
WO2017023987A1 (en) 2015-08-03 2017-02-09 Samumed, Llc. 3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof
WO2017023980A1 (en) 2015-08-03 2017-02-09 Samumed, Llc. 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof
US10206908B2 (en) 2015-08-03 2019-02-19 Samumed, Llc 3-(1H-pyrrolo[3,2-C]pyridin-2-YL)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof
US10188634B2 (en) 2015-08-03 2019-01-29 Samumed, Llc 3-(3H-imidazo[4,5-C]pyridin-2-yl)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
US10329309B2 (en) 2015-08-03 2019-06-25 Samumed, Llc 3-(3H-imidazo[4,5-B]pyridin-2-yl)-1H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
WO2017024003A1 (en) 2015-08-03 2017-02-09 Samumed, Llc 3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
WO2017024025A1 (en) 2015-08-03 2017-02-09 Sunil Kumar Kc 3-(1h-pyrrolo[2,3-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
US10206909B2 (en) 2015-08-03 2019-02-19 Samumed, Llc 3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
WO2017023993A1 (en) 2015-08-03 2017-02-09 Samumed, Llc. 3-(1h-indol-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
US10463651B2 (en) 2015-08-03 2019-11-05 Samumed, Llc 3-(1H-pyrrolo[3,2-C]pyridin-2-YL)-1H-indazoles and therapeutic uses thereof
WO2017023996A1 (en) 2015-08-03 2017-02-09 Samumed, Llc. 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof
WO2017023989A1 (en) 2015-08-03 2017-02-09 Samumed, Llc. 3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
WO2017023972A1 (en) 2015-08-03 2017-02-09 Samumed, Llc. 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
US10383861B2 (en) 2015-08-03 2019-08-20 Sammumed, LLC 3-(1H-pyrrolo[2,3-C]pyridin-2-yl)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof
WO2017024021A1 (en) 2015-08-03 2017-02-09 Samumed, Llc 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof
WO2017024026A1 (en) 2015-08-03 2017-02-09 Samumed, Llc 3-(1h-indol-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof
US10604512B2 (en) 2015-08-03 2020-03-31 Samumed, Llc 3-(1H-indol-2-yl)-1H-indazoles and therapeutic uses thereof
KR20180080262A (ko) 2015-11-06 2018-07-11 사뮤메드, 엘엘씨 골관절염의 치료
EP3377009B1 (en) 2015-11-20 2020-10-28 ForSight Vision4, Inc. Porous structures for extended release drug delivery devices
CN113017981B (zh) 2016-04-05 2023-07-25 弗赛特影像4股份有限公司 药物递送装置
AR108325A1 (es) 2016-04-27 2018-08-08 Samumed Llc Isoquinolin-3-il carboxamidas y preparación y uso de las mismas
AR108326A1 (es) 2016-04-27 2018-08-08 Samumed Llc Isoquinolin-3-il carboxamidas y preparación y uso de las mismas
SMT202200486T1 (it) 2016-06-01 2023-01-13 Biosplice Therapeutics Inc Processo per la preparazione di n-(5-(3-(7-(3- fluorofen il)-3h-imidaz0[4,5-c]piridin-2-il)-1h-indazol-5- il)piridin-3-il)-3-metilbutanammide
KR102593742B1 (ko) 2016-10-21 2023-10-24 사뮤메드, 엘엘씨 인다졸-3-카복사마이드를 사용하는 방법 및 wnt/b-카테닌 신호전달 경로 억제제로서의 그들의 용도
MA46696A (fr) 2016-11-07 2019-09-11 Samumed Llc Formulations injectables à dose unique prêtes à l'emploi
WO2019079626A1 (en) 2017-10-19 2019-04-25 Samumed, Llc 6- (HETEROARYL 5-CHAIN) ISOQUINOLIN-3-YL CARBOXAMIDES, THEIR PREPARATION AND THEIR USE
US10413537B2 (en) 2017-10-27 2019-09-17 Samumed, Llc 6-(5-membered heteroaryl)isoquinolin-3-yl-(5-membered heteroaryl) carboxamides and preparation and use thereof
US10653688B2 (en) 2017-10-27 2020-05-19 Samumed, Llc 6-(6-membered heteroaryl and aryl)isoquinolin-3-yl carboxamides and preparation and use thereof
WO2019089835A1 (en) 2017-10-31 2019-05-09 Samumed, Llc Diazanaphthalen-3-yl carboxamides and preparation and use thereof
EP3713528A1 (en) 2017-11-21 2020-09-30 ForSight Vision4, Inc. Fluid exchange apparatus for expandable port delivery system and methods of use
MA51908A (fr) 2018-02-23 2021-06-02 Samumed Llc Indazole-3-carboxamides substitués par hétéroaryle en position 5, préparation et utilisation associées
WO2019215274A1 (en) 2018-05-09 2019-11-14 Ferrosan Medical Devices A/S Method for preparing a haemostatic composition
WO2019241540A1 (en) 2018-06-15 2019-12-19 Samumed, Llc Indazole containing macrocycles and therapeutic uses thereof
US10654833B2 (en) 2018-06-28 2020-05-19 Hepatikos Therapeutics, Llc ASK1 isoindolin-1-one inhibitors and methods of use thereof
WO2020150545A1 (en) 2019-01-17 2020-07-23 Samumed, Llc Pyrazole derivatives as modulators of the wnt/b-catenin signaling pathway
BR112022007332A2 (pt) 2019-10-24 2022-07-05 E Labombard Denis Dispositivo ocular, métodos, composição, caixa para conter e dispensar um dispositivo ocular e kit
WO2021168341A1 (en) 2020-02-21 2021-08-26 Samumed, Llc Solid forms of 1-(5-(3-(7-(3-fluorophenyl)-3h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridin-5-yl)pyridin-3-yl)-n,n-dimethylmethanamine
WO2023030435A1 (en) 2021-09-01 2023-03-09 Shanghai Qisheng Biological Preparation Co., Ltd. Cartilage regeneration using injectable, in situ polymerizable collagen compositions containing chondrocytes or stem cells
EP4415817A1 (en) 2021-10-12 2024-08-21 BioSplice Therapeutics, Inc. 1h-pyrrolo[2,3-b]pyridines as dyrk1a inhibitors
CA3234831A1 (en) 2021-10-12 2023-04-20 Biosplice Therapeutics, Inc. Pyrrolo[2,1-f][1,2,4]triazines derivatives as inhibitors of dyrk1a
CN118434792A (zh) 2021-12-28 2024-08-02 上海其胜生物制剂有限公司 透明质酸-胶原共聚物组合物及其医学应用
USD1033637S1 (en) 2022-01-24 2024-07-02 Forsight Vision4, Inc. Fluid exchange device
CN119604506A (zh) 2022-06-23 2025-03-11 拜斯丽治疗有限公司 4-烷氧基吡咯并[2,1-f][1,2,4]三嗪以及其制备和用途
US20240199649A1 (en) 2022-11-03 2024-06-20 Biosplice Therapeutics, Inc. 4-aminopyrrolo[2,1-f][1,2,4]triazines and preparation and uses thereof
WO2024211797A1 (en) 2023-04-07 2024-10-10 Biosplice Therapeutics, Inc. Pyrrolo[2,1-f][1,2,4]triazines and preparation and uses thereof
US20250206746A1 (en) 2023-12-22 2025-06-26 Biosplice Therapeutics, Inc. 4-alkoxypyrrolo[2,1-f][1,2,4]triazines and preparation and uses thereof
WO2025231425A1 (en) 2024-05-03 2025-11-06 Biosplice Therapeutics, Inc. 4-aminopyrrolo[2,l-f][l,2,4]triazines and preparation and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5325006B2 (OSRAM) * 1973-08-17 1978-07-24

Also Published As

Publication number Publication date
JPS6145608B2 (OSRAM) 1986-10-08
NZ188435A (en) 1981-03-16
AU4000078A (en) 1980-03-27
US4164559A (en) 1979-08-14
PH13977A (en) 1980-11-20
GB1594805A (en) 1981-08-05
JPS5446817A (en) 1979-04-13

Similar Documents

Publication Publication Date Title
AU520078B2 (en) Collagen drug delivery device
YU101478A (en) Medicine delivering device
GB2005538B (en) Pharmaceutical compositsions
GB2010681B (en) Syringe
YU80178A (en) Medicine inhalating device
YU39670B (en) Device for drug spraying
JPS5445993A (en) Pump for medical injection device
JPS5439991A (en) Medical operational stand
JPS54490A (en) Dental therapic device
ZA777060B (en) Medicament deliver means
GB1557151A (en) Conveying device
GB2008101B (en) Pharmaceutical preperations
ZA783232B (en) Device for administering medicinal substances
GB1550016A (en) Syringes
JPS5492617A (en) Medicine sending apparatus
JPS5389725A (en) Programmable rhythm device
JPS53126787A (en) Medical device
JPS5463099A (en) Medicine
ZA782139B (en) Device for dispensing medicaments
JPS5439994A (en) Device for administering delivery inducing medicine
JPS5486604A (en) Antiiinflammatory medicine
JPS5473126A (en) Antiicancer medicine
JPS5424484A (en) Device for administering medicine
GB2006161B (en) Liqiud delivery system
JPS5387081A (en) Tape delivery device