BR112013002553A2 - implantes à base de colágeno para distribuição sustentada de drogas - Google Patents

implantes à base de colágeno para distribuição sustentada de drogas

Info

Publication number
BR112013002553A2
BR112013002553A2 BR112013002553A BR112013002553A BR112013002553A2 BR 112013002553 A2 BR112013002553 A2 BR 112013002553A2 BR 112013002553 A BR112013002553 A BR 112013002553A BR 112013002553 A BR112013002553 A BR 112013002553A BR 112013002553 A2 BR112013002553 A2 BR 112013002553A2
Authority
BR
Brazil
Prior art keywords
collagen
drug delivery
sustained drug
based implants
implants
Prior art date
Application number
BR112013002553A
Other languages
English (en)
Inventor
Bruce H Dewoolfson
Dale P Devore
Eliot Lazar
Original Assignee
Euclid Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euclid Systems Corp filed Critical Euclid Systems Corp
Publication of BR112013002553A2 publication Critical patent/BR112013002553A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts, ocular implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

implantes à base de colágeno para distribuição sustentada de drogas. a revelação provê constructos baseados em colágeno para uso em distribuição de droga.
BR112013002553A 2010-08-02 2011-08-01 implantes à base de colágeno para distribuição sustentada de drogas BR112013002553A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36999610P 2010-08-02 2010-08-02
PCT/US2011/046098 WO2012018715A1 (en) 2010-08-02 2011-08-01 Collagen-based implants for sustained delivery of drugs

Publications (1)

Publication Number Publication Date
BR112013002553A2 true BR112013002553A2 (pt) 2016-05-31

Family

ID=45559775

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013002553A BR112013002553A2 (pt) 2010-08-02 2011-08-01 implantes à base de colágeno para distribuição sustentada de drogas

Country Status (11)

Country Link
US (1) US9289396B2 (pt)
EP (1) EP2600834A4 (pt)
JP (1) JP2013535485A (pt)
KR (1) KR20130108269A (pt)
CN (1) CN103189047A (pt)
AU (1) AU2011285964A1 (pt)
BR (1) BR112013002553A2 (pt)
CA (1) CA2807376A1 (pt)
MX (1) MX2013001310A (pt)
SG (1) SG187664A1 (pt)
WO (1) WO2012018715A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5137841B2 (ja) 2005-10-13 2013-02-06 シンセス ゲーエムベーハー 薬物含浸容器
US11033624B2 (en) 2010-06-02 2021-06-15 Novaflux Inc. Medical item for prevention and treatment of ear infection
US9622911B2 (en) 2010-09-30 2017-04-18 Cxl Ophthalmics, Llc Ophthalmic treatment device, system, and method of use
TWI590843B (zh) * 2011-12-28 2017-07-11 信迪思有限公司 膜及其製造方法
EP2830627B1 (en) 2012-03-29 2024-05-01 Epion Therapeutics, Inc. Ocular treatment solutions, delivery devices and delivery augmentation methods
US9566301B2 (en) 2012-03-29 2017-02-14 Cxl Ophthalmics, Llc Compositions and methods for treating or preventing diseases associated with oxidative stress
DE102012111808B4 (de) * 2012-12-05 2022-11-17 Universität Rostock Bioabbaubare Kombination zur Behandlung eines Glaukoms
MX370217B (es) 2013-03-04 2019-12-05 Shanghai Haohai Biological Tech Co Ltd Composicion inyectable de colageno polimerizable in situ.
US20160144067A1 (en) 2013-06-21 2016-05-26 DePuy Synthes Products, Inc. Films and methods of manufacture
US10285865B2 (en) * 2014-05-02 2019-05-14 Novaflux Inc. Drug-releasing device usable in mucosal body cavities
CN105266952A (zh) * 2014-07-09 2016-01-27 首都医科大学附属北京同仁医院 一种抗青光眼手术中所用防术后结膜粘连的器材
PL3305339T3 (pl) * 2015-06-03 2021-09-27 Sewon Cellontech Co., Ltd Sposób wytwarzania filmu kolagenowego z użyciem światła nadfioletowego, film kolagenowy wytworzony z jego użyciem oraz biomateriał wytworzony z użyciem filmu kolagenowego
CN118750585A (zh) 2017-04-06 2024-10-11 莎思坦控股有限责任公司 基于胶原的药物组合物和装置和生产方法及其用途
JP7554484B2 (ja) * 2018-05-14 2024-09-20 ルースターバイオ,インコーポレイテッド 細胞の高張液に由来する細胞外物質に関連する方法及び組成物
EP3958889A4 (en) 2019-04-22 2022-12-28 Sustain Holdings, LLC PEPTIDE COLLAGEN DRUG COMPOSITIONS AND DEVICES AND METHODS FOR PRODUCING THEM AND USING THEM
CN111297723A (zh) * 2020-03-25 2020-06-19 宁波赛缪斯生物科技有限公司 一种胶原蛋白的制备方法及其应用的制备方法
CN111374940A (zh) * 2020-04-13 2020-07-07 宁波赛缪斯生物科技有限公司 一种可原位聚合的胶原注射剂及其使用方法
US20240252446A1 (en) * 2023-01-31 2024-08-01 Sustained Drug Delivery Llc Derivatized collagen-hyaluronic acid based implants for sustained delivery of ophthalmic drugs

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4164559A (en) * 1977-09-21 1979-08-14 Cornell Research Foundation, Inc. Collagen drug delivery device
US4851513A (en) * 1985-09-06 1989-07-25 Minnesota Mining And Manufacturing Company Viscoelastic collagen solution for opthalmic use and method of preparation
US5219895A (en) 1991-01-29 1993-06-15 Autogenesis Technologies, Inc. Collagen-based adhesives and sealants and methods of preparation and use thereof
US5259998A (en) * 1991-10-04 1993-11-09 Chiron Ophthalmics, Inc. Method for casting dissolvable ophthalmic shields in a mold
IL105529A0 (en) * 1992-05-01 1993-08-18 Amgen Inc Collagen-containing sponges as drug delivery for proteins
US6261547B1 (en) * 1998-04-07 2001-07-17 Alcon Manufacturing, Ltd. Gelling ophthalmic compositions containing xanthan gum
JP2011520805A (ja) 2008-05-09 2011-07-21 キューエルティー プラグ デリバリー,インク. 緑内障および高眼圧症治療のための活性剤の持続送達

Also Published As

Publication number Publication date
EP2600834A1 (en) 2013-06-12
JP2013535485A (ja) 2013-09-12
CN103189047A (zh) 2013-07-03
US9289396B2 (en) 2016-03-22
CA2807376A1 (en) 2012-02-09
MX2013001310A (es) 2013-03-18
WO2012018715A1 (en) 2012-02-09
US20130129807A1 (en) 2013-05-23
SG187664A1 (en) 2013-03-28
KR20130108269A (ko) 2013-10-02
EP2600834A4 (en) 2013-12-25
AU2011285964A1 (en) 2013-02-28

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]