AU515038B2 - Preparation of alpha-l-asparty-l-phenyl alanine methyl ester - Google Patents

Preparation of alpha-l-asparty-l-phenyl alanine methyl ester

Info

Publication number
AU515038B2
AU515038B2 AU32014/77A AU3201477A AU515038B2 AU 515038 B2 AU515038 B2 AU 515038B2 AU 32014/77 A AU32014/77 A AU 32014/77A AU 3201477 A AU3201477 A AU 3201477A AU 515038 B2 AU515038 B2 AU 515038B2
Authority
AU
Australia
Prior art keywords
asparty
alpha
preparation
methyl ester
alanine methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU32014/77A
Other languages
English (en)
Other versions
AU3201477A (en
Inventor
G. L. and Vineyard B. D Bachman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Co
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of AU3201477A publication Critical patent/AU3201477A/en
Application granted granted Critical
Publication of AU515038B2 publication Critical patent/AU515038B2/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06104Dipeptides with the first amino acid being acidic
    • C07K5/06113Asp- or Asn-amino acid
    • C07K5/06121Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Seasonings (AREA)
AU32014/77A 1976-12-27 1977-12-23 Preparation of alpha-l-asparty-l-phenyl alanine methyl ester Expired AU515038B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75429776A 1976-12-27 1976-12-27
USUS754297 1976-12-27

Publications (2)

Publication Number Publication Date
AU3201477A AU3201477A (en) 1979-06-28
AU515038B2 true AU515038B2 (en) 1981-03-12

Family

ID=25034194

Family Applications (1)

Application Number Title Priority Date Filing Date
AU32014/77A Expired AU515038B2 (en) 1976-12-27 1977-12-23 Preparation of alpha-l-asparty-l-phenyl alanine methyl ester

Country Status (18)

Country Link
JP (1) JPS6050200B2 (nl)
AU (1) AU515038B2 (nl)
BE (1) BE862258A (nl)
BR (1) BR7708632A (nl)
CA (1) CA1100487A (nl)
CH (1) CH631435A5 (nl)
DE (1) DE2757771A1 (nl)
DK (1) DK149432C (nl)
FR (1) FR2375194A1 (nl)
GB (1) GB1546979A (nl)
HU (1) HU179735B (nl)
IT (1) IT1088938B (nl)
MX (1) MX4704E (nl)
NL (1) NL185211C (nl)
NO (1) NO148069C (nl)
SE (1) SE440506B (nl)
SU (1) SU884564A3 (nl)
ZA (1) ZA777614B (nl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU586669B2 (en) * 1985-03-29 1989-07-20 Mitsui Toatsu Chemicals Inc. Preparation process of ```-L-aspartyl-L-phenylalanine methyl ester or hydrochloride thereof

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59219258A (ja) * 1983-05-28 1984-12-10 Ajinomoto Co Inc α−L−アスパルチル−L−フエニルアラニンメチルエステル又はその塩酸塩の製法
US4618695A (en) * 1983-06-02 1986-10-21 Ajinomoto Co., Inc. Method of preparing methyl ester and its hydrochloride
JPS59225152A (ja) * 1983-06-02 1984-12-18 Ajinomoto Co Inc α−L−アスパルチル−L−フエニルアラニンメチルエステル又はその塩酸塩の製法
GB8321802D0 (en) * 1983-08-12 1983-09-14 Erba Farmitalia Aspartame synthesis
JPH07636B2 (ja) * 1984-12-17 1995-01-11 三井東圧化学株式会社 N−ホルミル−α−アスパルチルフエニルアラニンの製造法
CA1277098C (en) * 1984-12-27 1990-11-27 Mitsui Toatsu Chemicals, Inc. Preparation process of -l-aspartyl-l-phenylalanine methyl ester
AU561384B2 (en) * 1985-03-26 1987-05-07 Mitsui Toatsu Chemicals Inc. Preparation of -l-aspartyl-l-phenylalanine methyl ester or hydrochloride thereof
DE3600731A1 (de) * 1986-01-13 1987-07-16 Green Cross Korea Verfahren zur herstellung von (alpha)-l-aspartyl-l-phenylalaninmethylester
JPS6383098A (ja) * 1986-09-27 1988-04-13 Ajinomoto Co Inc α−L−アスパルチル−L−フエニルアラニン又はその誘導体の製造方法
DE3780585T2 (de) * 1986-12-05 1993-03-18 Mitsui Toatsu Chemicals Herstellung von alpha-l-aspartyl-l-phenylalanin-methylester oder deren hydrohalide.
JPH0832719B2 (ja) * 1986-12-19 1996-03-29 三井東圧化学株式会社 吸湿性の小さいα−L−アスパルチル−L−フエニルアラニンメチルエステルの製造法
JPS6411999U (nl) * 1987-07-13 1989-01-23

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5232371B2 (nl) * 1972-07-20 1977-08-20
US3933781A (en) * 1973-11-05 1976-01-20 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters
JPS5223001A (en) * 1975-08-14 1977-02-21 Ajinomoto Co Inc Process for elimination of formyl group

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU586669B2 (en) * 1985-03-29 1989-07-20 Mitsui Toatsu Chemicals Inc. Preparation process of ```-L-aspartyl-L-phenylalanine methyl ester or hydrochloride thereof

Also Published As

Publication number Publication date
NO148069C (no) 1983-08-03
SE7714709L (sv) 1978-06-28
IT1088938B (it) 1985-06-10
FR2375194A1 (fr) 1978-07-21
AU3201477A (en) 1979-06-28
MX4704E (es) 1982-08-04
DK577977A (da) 1978-06-28
JPS5382752A (en) 1978-07-21
NL7714351A (nl) 1978-06-29
ZA777614B (en) 1978-10-25
BR7708632A (pt) 1978-08-22
NO774440L (no) 1978-06-28
BE862258A (fr) 1978-06-23
CA1100487A (en) 1981-05-05
JPS6050200B2 (ja) 1985-11-07
GB1546979A (en) 1979-06-06
DK149432C (da) 1987-04-21
NO148069B (no) 1983-04-25
DE2757771A1 (de) 1978-07-06
HU179735B (en) 1982-12-28
NL185211B (nl) 1989-09-18
DK149432B (da) 1986-06-09
NL185211C (nl) 1990-02-16
SU884564A3 (ru) 1981-11-23
CH631435A5 (en) 1982-08-13
DE2757771C2 (nl) 1988-08-25
SE440506B (sv) 1985-08-05
FR2375194B1 (nl) 1984-04-13

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