DK149432C - Fremgangsmaade til fremstilling af alfa-l-aspartyl-l-phenylalanin-methylester - Google Patents

Fremgangsmaade til fremstilling af alfa-l-aspartyl-l-phenylalanin-methylester

Info

Publication number
DK149432C
DK149432C DK577977A DK577977A DK149432C DK 149432 C DK149432 C DK 149432C DK 577977 A DK577977 A DK 577977A DK 577977 A DK577977 A DK 577977A DK 149432 C DK149432 C DK 149432C
Authority
DK
Denmark
Prior art keywords
aspartyl
procedure
methyl ester
phenylalanine methyl
alfa
Prior art date
Application number
DK577977A
Other languages
English (en)
Other versions
DK149432B (da
DK577977A (da
Inventor
Gerald Lee Bachman
Billy Dale Vineyard
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of DK577977A publication Critical patent/DK577977A/da
Publication of DK149432B publication Critical patent/DK149432B/da
Application granted granted Critical
Publication of DK149432C publication Critical patent/DK149432C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06104Dipeptides with the first amino acid being acidic
    • C07K5/06113Asp- or Asn-amino acid
    • C07K5/06121Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Seasonings (AREA)
DK577977A 1976-12-27 1977-12-23 Fremgangsmaade til fremstilling af alfa-l-aspartyl-l-phenylalanin-methylester DK149432C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75429776A 1976-12-27 1976-12-27
US75429776 1976-12-27

Publications (3)

Publication Number Publication Date
DK577977A DK577977A (da) 1978-06-28
DK149432B DK149432B (da) 1986-06-09
DK149432C true DK149432C (da) 1987-04-21

Family

ID=25034194

Family Applications (1)

Application Number Title Priority Date Filing Date
DK577977A DK149432C (da) 1976-12-27 1977-12-23 Fremgangsmaade til fremstilling af alfa-l-aspartyl-l-phenylalanin-methylester

Country Status (18)

Country Link
JP (1) JPS6050200B2 (da)
AU (1) AU515038B2 (da)
BE (1) BE862258A (da)
BR (1) BR7708632A (da)
CA (1) CA1100487A (da)
CH (1) CH631435A5 (da)
DE (1) DE2757771A1 (da)
DK (1) DK149432C (da)
FR (1) FR2375194A1 (da)
GB (1) GB1546979A (da)
HU (1) HU179735B (da)
IT (1) IT1088938B (da)
MX (1) MX4704E (da)
NL (1) NL185211C (da)
NO (1) NO148069C (da)
SE (1) SE440506B (da)
SU (1) SU884564A3 (da)
ZA (1) ZA777614B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59219258A (ja) * 1983-05-28 1984-12-10 Ajinomoto Co Inc α−L−アスパルチル−L−フエニルアラニンメチルエステル又はその塩酸塩の製法
US4618695A (en) * 1983-06-02 1986-10-21 Ajinomoto Co., Inc. Method of preparing methyl ester and its hydrochloride
JPS59225152A (ja) * 1983-06-02 1984-12-18 Ajinomoto Co Inc α−L−アスパルチル−L−フエニルアラニンメチルエステル又はその塩酸塩の製法
GB8321802D0 (en) * 1983-08-12 1983-09-14 Erba Farmitalia Aspartame synthesis
JPH07636B2 (ja) * 1984-12-17 1995-01-11 三井東圧化学株式会社 N−ホルミル−α−アスパルチルフエニルアラニンの製造法
ES8703487A1 (es) * 1984-12-27 1987-03-01 Mitsui Toatsu Chemicals Procedimiento para la preparacion de a-l-aspartil-l-fenila- lanina metil ester
AU561384B2 (en) * 1985-03-26 1987-05-07 Mitsui Toatsu Chemicals Inc. Preparation of -l-aspartyl-l-phenylalanine methyl ester or hydrochloride thereof
AU586669B2 (en) * 1985-03-29 1989-07-20 Mitsui Toatsu Chemicals Inc. Preparation process of ```-L-aspartyl-L-phenylalanine methyl ester or hydrochloride thereof
DE3600731A1 (de) * 1986-01-13 1987-07-16 Green Cross Korea Verfahren zur herstellung von (alpha)-l-aspartyl-l-phenylalaninmethylester
JPS6383098A (ja) * 1986-09-27 1988-04-13 Ajinomoto Co Inc α−L−アスパルチル−L−フエニルアラニン又はその誘導体の製造方法
DE3780585T2 (de) * 1986-12-05 1993-03-18 Mitsui Toatsu Chemicals Herstellung von alpha-l-aspartyl-l-phenylalanin-methylester oder deren hydrohalide.
JPH0832719B2 (ja) * 1986-12-19 1996-03-29 三井東圧化学株式会社 吸湿性の小さいα−L−アスパルチル−L−フエニルアラニンメチルエステルの製造法
JPS6411999U (da) * 1987-07-13 1989-01-23

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5232371B2 (da) * 1972-07-20 1977-08-20
US3933781A (en) * 1973-11-05 1976-01-20 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters
JPS5223001A (en) * 1975-08-14 1977-02-21 Ajinomoto Co Inc Process for elimination of formyl group

Also Published As

Publication number Publication date
DK149432B (da) 1986-06-09
BE862258A (fr) 1978-06-23
CA1100487A (en) 1981-05-05
CH631435A5 (en) 1982-08-13
FR2375194B1 (da) 1984-04-13
HU179735B (en) 1982-12-28
SE440506B (sv) 1985-08-05
NO148069C (no) 1983-08-03
JPS5382752A (en) 1978-07-21
NL7714351A (nl) 1978-06-29
ZA777614B (en) 1978-10-25
DE2757771A1 (de) 1978-07-06
AU515038B2 (en) 1981-03-12
NO774440L (no) 1978-06-28
GB1546979A (en) 1979-06-06
SE7714709L (sv) 1978-06-28
FR2375194A1 (fr) 1978-07-21
NO148069B (no) 1983-04-25
DK577977A (da) 1978-06-28
IT1088938B (it) 1985-06-10
BR7708632A (pt) 1978-08-22
AU3201477A (en) 1979-06-28
NL185211C (nl) 1990-02-16
DE2757771C2 (da) 1988-08-25
MX4704E (es) 1982-08-04
NL185211B (nl) 1989-09-18
JPS6050200B2 (ja) 1985-11-07
SU884564A3 (ru) 1981-11-23

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PUP Patent expired