AU508764B2 - Glucosamine derivatives - Google Patents

Glucosamine derivatives

Info

Publication number
AU508764B2
AU508764B2 AU20422/76A AU2042276A AU508764B2 AU 508764 B2 AU508764 B2 AU 508764B2 AU 20422/76 A AU20422/76 A AU 20422/76A AU 2042276 A AU2042276 A AU 2042276A AU 508764 B2 AU508764 B2 AU 508764B2
Authority
AU
Australia
Prior art keywords
glucosamine derivatives
glucosamine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU20422/76A
Other languages
English (en)
Other versions
AU2042276A (en
Inventor
G. Hartmann A. Stanek J. and Sele A Haichang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of AU2042276A publication Critical patent/AU2042276A/en
Application granted granted Critical
Publication of AU508764B2 publication Critical patent/AU508764B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU20422/76A 1975-12-10 1976-12-09 Glucosamine derivatives Expired AU508764B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CHCH16042/75 1975-12-10
CH1604275A CH613709A5 (en) 1975-12-10 1975-12-10 Process for the preparation of glucosamine derivatives

Publications (2)

Publication Number Publication Date
AU2042276A AU2042276A (en) 1978-06-15
AU508764B2 true AU508764B2 (en) 1980-04-03

Family

ID=4414012

Family Applications (1)

Application Number Title Priority Date Filing Date
AU20422/76A Expired AU508764B2 (en) 1975-12-10 1976-12-09 Glucosamine derivatives

Country Status (30)

Country Link
JP (1) JPS5273820A (no)
AR (2) AR224091A1 (no)
AT (1) AT365607B (no)
AU (1) AU508764B2 (no)
BE (1) BE849214A (no)
CA (1) CA1262400A (no)
CH (2) CH613709A5 (no)
CS (4) CS205026B2 (no)
DD (1) DD129781A5 (no)
DE (1) DE2655500A1 (no)
DK (1) DK154654C (no)
ES (2) ES454118A1 (no)
FI (1) FI64164C (no)
FR (1) FR2361902A1 (no)
GB (1) GB1570625A (no)
GR (1) GR61647B (no)
HK (1) HK32883A (no)
HU (1) HU177970B (no)
IE (1) IE44190B1 (no)
IL (1) IL51076A (no)
MY (1) MY8400123A (no)
NL (1) NL7613666A (no)
NO (1) NO144850C (no)
NZ (1) NZ182837A (no)
PL (4) PL110787B1 (no)
PT (1) PT65946B (no)
SE (1) SE445923B (no)
SG (1) SG11083G (no)
SU (3) SU660589A3 (no)
ZA (1) ZA767333B (no)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
US4370265A (en) * 1974-10-22 1983-01-25 Agence Nationale De Valorisation Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
GB1571133A (en) * 1976-04-26 1980-07-09 Syntex Inc Immuniological adjuvant peptidoglycans compounds and methods of preparation thereof
DE2862107D1 (en) 1977-12-02 1982-11-18 Takeda Chemical Industries Ltd Glucosamine-peptide derivatives and their pharmaceutical compositions
US4397844A (en) * 1978-02-24 1983-08-09 Ciba-Geigy Corporation Antigen derivatives and processes for their preparation
CA1138436A (en) * 1978-02-24 1982-12-28 Gerhard Baschang Process for the manufacture of novel antigens
FR2442241A2 (fr) * 1978-03-20 1980-06-20 Anvar Nouveaux composes esters de muramyl-peptide, leur preparation et les compositions pharmaceutiques les contenant, notamment sous forme de liposomes
FR2420545A1 (fr) * 1978-03-20 1979-10-19 Anvar Nouveaux esters de l'acide n-acetyl-muramyl-aminoacyl-glutamique ou des derives de substitution de celui-ci a proprietes anti-infectieuses et/ou d'adjuvants immunologiques
FR2428050A1 (fr) * 1978-06-05 1980-01-04 Anvar Oligomeres de composes du type muramyl-peptide et medicaments les contenant
FR2428051A1 (fr) * 1978-06-05 1980-01-04 Anvar Nouveaux composes du type muramyl-peptide et medicaments les contenant
FR2446292A1 (fr) * 1979-01-12 1980-08-08 Anvar Muramyl-peptides fixes sur polymeres peptidiques et medicaments les contenant
US4256735A (en) 1979-01-29 1981-03-17 Merck & Co., Inc. Immunologically active dipeptidyl saccharides and methods of preparation
FR2449697A1 (fr) 1979-02-20 1980-09-19 Anvar Nouveaux muramyl-peptides substitues sur un azote peptidique et medicaments les contenant
JPS55111499A (en) * 1979-02-21 1980-08-28 Takeda Chem Ind Ltd Glucosamine derivative and its preparation
JPS5618996A (en) * 1979-06-21 1981-02-23 Dai Ichi Seiyaku Co Ltd Muramyldipeptide derivative
FI75578C (fi) 1979-07-25 1988-07-11 Ciba Geigy Ag Analogifoerfarande foer framstaellning av farmakologiskt verkande lipofila fosfatidylmuramylpeptider.
JPS5649396A (en) * 1979-09-28 1981-05-02 Dai Ichi Seiyaku Co Ltd Novel muramyldipeptide derivative
EP0026746B1 (de) * 1979-10-02 1985-04-10 Ciba-Geigy Ag Kombinationspräparate zur Anwendung in einem Verfahren zur Steigerung der Wirkung von Antibiotika, antibiotische Präparate mit gesteigerter Wirksamkeit und Verfahren zu deren Herstellung
FI803077A (fi) 1979-10-12 1981-04-13 Ciba Geigy Ag Foerfarande foer framstaellning av myramylpeptider
US4409209A (en) * 1979-10-12 1983-10-11 Ciba-Geigy Corporation Novel phosphorylmuramyl peptides and processes for the manufacture thereof
US4406889A (en) * 1980-02-15 1983-09-27 Ciba-Geigy Corporation Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use
US4368190A (en) * 1980-04-17 1983-01-11 Merck & Co., Inc. Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation
US4310514A (en) 1980-05-05 1982-01-12 Merck & Co., Inc. Immunologically active dipeptidyl 5-0,6-0-acyl-2-amino-2-deoxy-D-glucofuranose derivatives and methods of preparation
EP0056560A1 (de) * 1981-01-19 1982-07-28 Ciba-Geigy Ag Antibiotische Präparate mit gesteigerter Wirksamkeit, Verfahren zu deren Herstellung und Verfahren zur Steigerung der antibiotischen Wirkung von Antibiotika
GR78246B (no) * 1981-01-23 1984-09-26 Ciba Geigy Ag
JPS6042398A (ja) * 1983-08-18 1985-03-06 Toshiyuki Hamaoka ムラミルジペプチド活性エステル誘導体
EP0541486A1 (de) * 1991-11-07 1993-05-12 Ciba-Geigy Ag Polycyclische Konjugate
WO2006118327A1 (ja) * 2005-04-27 2006-11-09 Oxygenix Co Ltd カチオン性アミノ酸型脂質
WO2016138286A1 (en) 2015-02-26 2016-09-01 Stc.Unm Irgm and precision autophagy controls for antimicrobial and inflammatory disease states and methods of detection of autophagy
US10927147B2 (en) 2015-12-10 2021-02-23 Bharat Biotech International Limited Muramyl peptide derivative compound, synthesis and uses thereof
US10576147B2 (en) * 2015-12-15 2020-03-03 Bharat Biotech International Limited Muramyl peptide derivative compound, synthesis and uses thereof
MX2020002010A (es) 2017-08-21 2020-07-13 Celgene Corp Procesos para la preparacion de 4,5-diamino-5-oxopentanoato de (s)-terc-butilo.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents

Also Published As

Publication number Publication date
AR220686A1 (es) 1980-11-28
FI64164B (fi) 1983-06-30
ZA767333B (en) 1977-11-30
DK154654C (da) 1989-05-08
CH613709A5 (en) 1979-10-15
SU747430A3 (ru) 1980-07-23
FR2361902B1 (no) 1980-11-07
DK552476A (da) 1977-06-11
IE44190B1 (en) 1981-09-09
CS205028B2 (en) 1981-04-30
SG11083G (en) 1983-09-16
SE7613851L (sv) 1977-06-11
DD129781A5 (de) 1978-02-08
PL110353B1 (en) 1980-07-31
PT65946B (en) 1978-06-14
FR2361902A1 (fr) 1978-03-17
PL194291A1 (pl) 1978-10-23
MY8400123A (en) 1984-12-31
AT365607B (de) 1982-02-10
NL7613666A (nl) 1977-06-14
DE2655500C2 (no) 1988-12-22
FI763541A (no) 1977-06-11
ATA909276A (de) 1981-06-15
PL110787B1 (en) 1980-07-31
ES454118A1 (es) 1978-03-01
NO144850C (no) 1981-11-25
PL110794B1 (en) 1980-07-31
HK32883A (en) 1983-09-02
NZ182837A (en) 1978-07-28
CS205025B2 (en) 1981-04-30
CS205027B2 (en) 1981-04-30
CS205026B2 (en) 1981-04-30
DE2655500A1 (de) 1977-06-23
AR224091A1 (es) 1981-10-30
DK154654B (da) 1988-12-05
IL51076A (en) 1980-09-16
FI64164C (fi) 1983-10-10
IE44190L (en) 1977-06-10
CA1262400A (en) 1989-10-17
BE849214A (fr) 1977-06-09
JPS638118B2 (no) 1988-02-19
PL112672B1 (en) 1980-10-31
IL51076A0 (en) 1977-02-28
GB1570625A (en) 1980-07-02
GR61647B (en) 1978-12-05
JPS5273820A (en) 1977-06-21
SU660589A3 (ru) 1979-04-30
HU177970B (en) 1982-02-28
ES465514A1 (es) 1978-09-16
SE445923B (sv) 1986-07-28
AU2042276A (en) 1978-06-15
PT65946A (en) 1977-01-01
SU1060118A3 (ru) 1983-12-07
CH614718A5 (en) 1979-12-14
NO144850B (no) 1981-08-17
NO764191L (no) 1977-06-13

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