AU506340B2 - Benzodiazepine derivatives - Google Patents

Benzodiazepine derivatives

Info

Publication number
AU506340B2
AU506340B2 AU86858/75A AU8685875A AU506340B2 AU 506340 B2 AU506340 B2 AU 506340B2 AU 86858/75 A AU86858/75 A AU 86858/75A AU 8685875 A AU8685875 A AU 8685875A AU 506340 B2 AU506340 B2 AU 506340B2
Authority
AU
Australia
Prior art keywords
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU86858/75A
Other languages
English (en)
Other versions
AU8685875A (en
Inventor
J. K. and Tupper D. E Chakrabarti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly Industries Ltd
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10459213&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU506340(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of AU8685875A publication Critical patent/AU8685875A/en
Application granted granted Critical
Publication of AU506340B2 publication Critical patent/AU506340B2/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU86858/75A 1974-11-26 1975-11-21 Benzodiazepine derivatives Expired AU506340B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB51240/74 1974-11-26
GB51240/74A GB1533235A (en) 1974-11-26 1974-11-26 Benzodiazepine derivatives

Publications (2)

Publication Number Publication Date
AU8685875A AU8685875A (en) 1977-05-26
AU506340B2 true AU506340B2 (en) 1979-12-20

Family

ID=10459213

Family Applications (1)

Application Number Title Priority Date Filing Date
AU86858/75A Expired AU506340B2 (en) 1974-11-26 1975-11-21 Benzodiazepine derivatives

Country Status (30)

Country Link
JP (1) JPS6044314B2 (enrdf_load_stackoverflow)
AR (1) AR221203A1 (enrdf_load_stackoverflow)
AT (1) AT351547B (enrdf_load_stackoverflow)
AU (1) AU506340B2 (enrdf_load_stackoverflow)
BE (1) BE835932A (enrdf_load_stackoverflow)
BG (1) BG29573A3 (enrdf_load_stackoverflow)
CA (1) CA1075687A (enrdf_load_stackoverflow)
CH (2) CH613455A5 (enrdf_load_stackoverflow)
CS (1) CS236753B2 (enrdf_load_stackoverflow)
DD (1) DD123343A5 (enrdf_load_stackoverflow)
DE (1) DE2552403C2 (enrdf_load_stackoverflow)
DK (1) DK146887C (enrdf_load_stackoverflow)
ES (1) ES443011A1 (enrdf_load_stackoverflow)
FR (1) FR2292479A1 (enrdf_load_stackoverflow)
GB (1) GB1533235A (enrdf_load_stackoverflow)
HK (1) HK58681A (enrdf_load_stackoverflow)
HU (1) HU172493B (enrdf_load_stackoverflow)
IE (1) IE42564B1 (enrdf_load_stackoverflow)
IL (1) IL48502A (enrdf_load_stackoverflow)
KE (1) KE3163A (enrdf_load_stackoverflow)
MY (1) MY8200149A (enrdf_load_stackoverflow)
NL (1) NL186088C (enrdf_load_stackoverflow)
NZ (1) NZ179335A (enrdf_load_stackoverflow)
PH (2) PH11669A (enrdf_load_stackoverflow)
PL (1) PL100135B1 (enrdf_load_stackoverflow)
RO (1) RO69912A (enrdf_load_stackoverflow)
SE (2) SE421209B (enrdf_load_stackoverflow)
SU (2) SU629879A3 (enrdf_load_stackoverflow)
YU (1) YU298375A (enrdf_load_stackoverflow)
ZA (1) ZA757344B (enrdf_load_stackoverflow)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL62792A (en) * 1980-05-07 1985-02-28 Byk Gulden Lomberg Chem Fab Acylated dihydrothienodiazepinone compounds,process for their preparation,and medicaments containing them
GB8819059D0 (en) * 1988-08-11 1988-09-14 Lilly Industries Ltd Benzodiazepine compounds & their use as pharmaceuticals
GB9009229D0 (en) 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
ATE198891T1 (de) * 1992-05-29 2001-02-15 Lilly Co Eli Thienobenzodiazepinderivate zur behandlung von störungen des zentralnervensystems
WO1997016430A1 (en) * 1995-11-01 1997-05-09 Merck & Co., Inc. Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
US6043358A (en) 1995-11-01 2000-03-28 Merck & Co., Inc. Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
DE69816102D1 (de) * 1997-09-02 2003-08-07 Mitsubishi Pharma Corp Kondensierte thiophenderivate und ihre medizinische anwendung
RU2185383C1 (ru) * 2001-05-22 2002-07-20 Институт молекулярной генетики РАН ВЫСОКОМЕЧЕННЫЙ ТРИТИЕМ 2-МЕТИЛ-4-(4-МЕТИЛ-1-ПИПЕРАЗИНИЛ)-10Н-ТИЕНО[2,3-b][1,5]БЕНЗОДИАЗЕПИН
PL199016B1 (pl) * 2002-06-20 2008-08-29 Adamed Sp Z Oo Sposób wytwarzania olanzapiny
SI21270A (sl) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
DE10301923B3 (de) * 2003-01-17 2004-09-16 Krka Tovarna Zdravil, D.D. Verfahren und Zwischenprodukte zur Herstellung von Olanzapin
AR047460A1 (es) * 2004-01-27 2006-01-18 Synthon Bv Proceso para la fabricacion de acetato de 2-metil-4-(4-metil-1-piperazinil)-10h-tieno[2,3-b][1,5]benzodiazepina (acetato de olanzapina)
AR048272A1 (es) 2004-03-18 2006-04-12 Lek Pharmaceuticals Sintesis de 2 metil - 4- (4- metil -1- piperazinil) - 10 h- tieno ( 2,3-b) (1,5) benzodiazepina y sus sales, metodos para su preparacion, composiciones farmaceuticas que la contienen y su uso en la fabricacion de medicamentos para el tratamiento de enfermedades mentales.
WO2006004931A2 (en) * 2004-06-30 2006-01-12 Athersys, Inc. Substituted azepine derivatives as serotonin receptor modulators
EP2292624A1 (en) 2009-07-20 2011-03-09 LEK Pharmaceuticals d.d. Process for the purification of olanzapine

Also Published As

Publication number Publication date
SE429045B (sv) 1983-08-08
AR221203A1 (es) 1981-01-15
CH613454A5 (en) 1979-09-28
IL48502A (en) 1980-01-31
HU172493B (hu) 1978-09-28
BE835932A (fr) 1976-05-25
IE42564L (en) 1976-05-26
YU298375A (en) 1982-10-31
CS236753B2 (en) 1985-05-15
DK146887B (da) 1984-01-30
CH613455A5 (en) 1979-09-28
SE7513185L (sv) 1976-05-27
AU8685875A (en) 1977-05-26
DK146887C (da) 1984-07-09
MY8200149A (en) 1982-12-31
PH11669A (en) 1978-05-19
NL186088C (nl) 1990-09-17
FR2292479B1 (enrdf_load_stackoverflow) 1978-07-28
CA1075687A (en) 1980-04-15
SU626702A3 (ru) 1978-09-30
PH24534A (en) 1990-08-03
ATA898275A (de) 1979-01-15
JPS6044314B2 (ja) 1985-10-02
ZA757344B (en) 1976-11-24
DE2552403C2 (de) 1986-06-19
DE2552403A1 (de) 1976-08-12
RO69912A (ro) 1980-08-15
SE421209B (sv) 1981-12-07
IE42564B1 (en) 1980-09-10
GB1533235A (en) 1978-11-22
BG29573A3 (en) 1980-12-12
PL100135B1 (pl) 1978-09-30
ES443011A1 (es) 1977-07-01
HK58681A (en) 1981-12-04
NL7513833A (nl) 1976-05-31
SE7812194L (sv) 1978-11-27
KE3163A (en) 1981-10-16
SU629879A3 (ru) 1978-10-25
JPS5176296A (en) 1976-07-01
FR2292479A1 (fr) 1976-06-25
DK524175A (da) 1976-05-27
NZ179335A (en) 1978-11-13
IL48502A0 (en) 1976-01-30
AT351547B (de) 1979-07-25
NL186088B (nl) 1990-04-17
DD123343A5 (enrdf_load_stackoverflow) 1976-12-12

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