AU4438601A - Therapeutic combinations of antihypertensive and antiangiogenic agents - Google Patents

Therapeutic combinations of antihypertensive and antiangiogenic agents

Info

Publication number
AU4438601A
AU4438601A AU4438601A AU4438601A AU4438601A AU 4438601 A AU4438601 A AU 4438601A AU 4438601 A AU4438601 A AU 4438601A AU 4438601 A AU4438601 A AU 4438601A AU 4438601 A AU4438601 A AU 4438601A
Authority
AU
Australia
Prior art keywords
antihypertensive
agent
therapeutic combinations
antiangiogenic agents
angiogenesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU4438601A
Other languages
English (en)
Inventor
Donald James Ogilvie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of AU4438601A publication Critical patent/AU4438601A/xx
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU4438601A 2000-04-05 2001-04-02 Therapeutic combinations of antihypertensive and antiangiogenic agents Pending AU4438601A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0008269.3A GB0008269D0 (en) 2000-04-05 2000-04-05 Combination chemotherapy
PCT/GB2001/001522 WO2001074360A1 (en) 2000-04-05 2001-04-02 Therapeutic combinations of antihypertensive and antiangiogenic agents

Publications (1)

Publication Number Publication Date
AU4438601A true AU4438601A (en) 2001-10-15

Family

ID=9889176

Family Applications (2)

Application Number Title Priority Date Filing Date
AU4438601A Pending AU4438601A (en) 2000-04-05 2001-04-02 Therapeutic combinations of antihypertensive and antiangiogenic agents
AU2001244386A Ceased AU2001244386B2 (en) 2000-04-05 2001-04-02 Therapeutic combinations of antihypertensive and antiangiogenic agents

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2001244386A Ceased AU2001244386B2 (en) 2000-04-05 2001-04-02 Therapeutic combinations of antihypertensive and antiangiogenic agents

Country Status (29)

Country Link
US (1) US7829573B2 (enExample)
EP (3) EP1790340A3 (enExample)
JP (1) JP2003528917A (enExample)
KR (2) KR20080034523A (enExample)
CN (1) CN1431902A (enExample)
AT (1) ATE355065T1 (enExample)
AU (2) AU4438601A (enExample)
BR (1) BR0109729A (enExample)
CA (1) CA2401854A1 (enExample)
CY (1) CY1107615T1 (enExample)
CZ (1) CZ299410B6 (enExample)
DE (1) DE60126923T2 (enExample)
DK (1) DK1272186T3 (enExample)
EE (1) EE200200578A (enExample)
ES (1) ES2280349T3 (enExample)
GB (1) GB0008269D0 (enExample)
HU (1) HUP0300426A2 (enExample)
IL (1) IL151503A0 (enExample)
IS (2) IS2455B (enExample)
MX (1) MXPA02009743A (enExample)
NO (2) NO323467B1 (enExample)
NZ (2) NZ520938A (enExample)
PL (1) PL357605A1 (enExample)
PT (1) PT1272186E (enExample)
RU (1) RU2002129353A (enExample)
SI (1) SI1272186T1 (enExample)
SK (1) SK14302002A3 (enExample)
WO (1) WO2001074360A1 (enExample)
ZA (1) ZA200206959B (enExample)

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PT1592423E (pt) * 2003-02-13 2011-06-16 Astrazeneca Ab Terapia de combinação de zd6474 com 5-fu e/ou cpt-11
GB0310401D0 (en) * 2003-05-07 2003-06-11 Astrazeneca Ab Therapeutic agent
GB0316127D0 (en) 2003-07-10 2003-08-13 Astrazeneca Ab Combination therapy
GB0316123D0 (en) * 2003-07-10 2003-08-13 Astrazeneca Ab Combination therapy
ATE478671T1 (de) * 2003-07-10 2010-09-15 Astrazeneca Ab Verwendung des chinazolin-derivats zd6474 in kombination mit platinverbindungen und optional ionisierender strahlung bei der behandlung von erkrankungen im zusammenhang mit angiogenese und/oder erhöhter gefässpermeabilität
US20080113039A1 (en) 2004-03-23 2008-05-15 Stephen Robert Wedge Combination Therapy
GB0406445D0 (en) 2004-03-23 2004-04-28 Astrazeneca Ab Combination therapy
GB0406446D0 (en) 2004-03-23 2004-04-28 Astrazeneca Ab Combination therapy
JP2008514577A (ja) * 2004-09-27 2008-05-08 アストラゼネカ アクチボラグ Ｚｄ６４７４及びイマチニブを含んでなる組合せ
KR20070073813A (ko) * 2004-09-27 2007-07-10 아스트라제네카 아베 Ａｚｄ2171 및 이마티닙을 포함하는 암의 병합 요법
GB0424339D0 (en) 2004-11-03 2004-12-08 Astrazeneca Ab Combination therapy
NZ564189A (en) * 2005-07-06 2011-04-29 Astrazeneca Ab Combination therapy of cancer with AZD2171 and gemcitabine
CA2633211A1 (en) 2005-12-15 2007-06-21 Astrazeneca Ab Combination of angiopoietin-2 antagonist and of vegf-a, kdr and/or flt1 antagonist for treating cancer
DK1971338T3 (da) * 2005-12-22 2011-05-23 Astrazeneca Ab Kombination af ZD6474 og pemetrexed
CA2631676A1 (en) 2005-12-22 2007-06-28 Astrazeneca Ab Combination of azd2171 and pemetrexed
JP2010504949A (ja) 2006-09-29 2010-02-18 アストラゼネカ アクチボラグ Ｚｄ６４７４とベバシズマブの癌療法のための組合せ
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KR20080034523A (ko) 2008-04-21
EP1790340A2 (en) 2007-05-30
PL357605A1 (en) 2004-07-26
RU2002129353A (ru) 2004-03-20
NO20024814D0 (no) 2002-10-04
JP2003528917A (ja) 2003-09-30
CN1431902A (zh) 2003-07-23
EP1272186B1 (en) 2007-02-28
ES2280349T3 (es) 2007-09-16
NO326277B1 (no) 2008-10-27
EE200200578A (et) 2004-06-15
NZ534455A (en) 2007-01-26
CY1107615T1 (el) 2013-03-13
SK14302002A3 (sk) 2003-05-02
DE60126923T2 (de) 2007-10-31
IS6557A (is) 2002-09-20
DK1272186T3 (da) 2007-05-21
US7829573B2 (en) 2010-11-09
AU2001244386B2 (en) 2005-01-27
MXPA02009743A (es) 2003-03-27
EP1790340A3 (en) 2009-03-18
IL151503A0 (en) 2003-04-10
US20030144298A1 (en) 2003-07-31
KR100849149B1 (ko) 2008-07-31
SI1272186T1 (sl) 2007-06-30
NO323467B1 (no) 2007-05-21
BR0109729A (pt) 2003-02-04
NZ520938A (en) 2005-08-26
IS2455B (is) 2008-11-15
WO2001074360A1 (en) 2001-10-11
GB0008269D0 (en) 2000-05-24
CZ299410B6 (cs) 2008-07-16
KR20030007491A (ko) 2003-01-23
EP1658849A3 (en) 2009-02-18
IS8726A (is) 2008-04-16
CA2401854A1 (en) 2001-10-11
HUP0300426A2 (hu) 2003-06-28
NO20062050L (no) 2001-10-08
EP1658849A2 (en) 2006-05-24
EP1272186A1 (en) 2003-01-08
PT1272186E (pt) 2007-04-30
NO20024814L (no) 2002-11-12
DE60126923D1 (de) 2007-04-12
ATE355065T1 (de) 2006-03-15
ZA200206959B (en) 2003-12-01

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