AU3719997A - Hypoglycemic and hypolipidemic compounds - Google Patents

Hypoglycemic and hypolipidemic compounds

Info

Publication number
AU3719997A
AU3719997A AU37199/97A AU3719997A AU3719997A AU 3719997 A AU3719997 A AU 3719997A AU 37199/97 A AU37199/97 A AU 37199/97A AU 3719997 A AU3719997 A AU 3719997A AU 3719997 A AU3719997 A AU 3719997A
Authority
AU
Australia
Prior art keywords
hypoglycemic
hypolipidemic compounds
hypolipidemic
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU37199/97A
Other languages
English (en)
Inventor
Samuel J. Dominianni
Margaret M. Faul
Russell D. Stucky
Leonard L. Winneroski Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of AU3719997A publication Critical patent/AU3719997A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU37199/97A 1996-07-01 1997-06-30 Hypoglycemic and hypolipidemic compounds Abandoned AU3719997A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2101696P 1996-07-01 1996-07-01
US60021016 1996-07-01
PCT/US1997/011576 WO1998000137A1 (en) 1996-07-01 1997-06-30 Hypoglycemic and hypolipidemic compounds

Publications (1)

Publication Number Publication Date
AU3719997A true AU3719997A (en) 1998-01-21

Family

ID=21801854

Family Applications (1)

Application Number Title Priority Date Filing Date
AU37199/97A Abandoned AU3719997A (en) 1996-07-01 1997-06-30 Hypoglycemic and hypolipidemic compounds

Country Status (8)

Country Link
US (3) US6194446B1 (enExample)
EP (1) EP0925063A4 (enExample)
JP (1) JP2000515133A (enExample)
AU (1) AU3719997A (enExample)
CA (1) CA2259487A1 (enExample)
IL (1) IL121202A (enExample)
WO (1) WO1998000137A1 (enExample)
ZA (1) ZA975865B (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9604242D0 (en) * 1996-02-28 1996-05-01 Glaxo Wellcome Inc Chemical compounds
JP3215048B2 (ja) 1996-04-03 2001-10-02 日本たばこ産業株式会社 プロピオン酸誘導体及びその用途
SK21099A3 (en) * 1996-08-19 2000-05-16 Japan Tobacco Inc Propionic acid derivatives and applications thereof
US6005102A (en) 1997-10-15 1999-12-21 American Home Products Corporation Aryloxy-alkyl-dialkylamines
ATE355264T1 (de) * 1997-10-15 2006-03-15 Wyeth Corp Neue aryloxy-alkyl-dialkylamine
US6221902B1 (en) 1998-05-12 2001-04-24 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
DE69904041D1 (de) * 1998-05-12 2003-01-02 Wyeth Corp Biphenylsulfonylarylcarbonsäuren verwendbar zur behandlung von insulin resistenz und hyperglycemia
AR016257A1 (es) * 1998-05-14 2001-06-20 Merck & Co Inc Proceso para la sintesis estereoselectiva de ariloxi-4-aza-5alfa-androstan-3-onas, 16 alfa y 16 beta-sustituidas e insustituidas, e intermediariosobtenidos en dicho proceso.
US6589969B1 (en) * 1998-10-16 2003-07-08 Ono Pharmaceutical Co., Ltd. Carboxylic acid derivatives and drugs containing the same as the active ingredient
US6310081B1 (en) * 1999-05-10 2001-10-30 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
EP1078923B1 (en) 1999-08-02 2006-03-08 F. Hoffmann-La Roche Ag Process for the preparation of benzothiophene derivatives
TW200514783A (en) 1999-09-22 2005-05-01 Bristol Myers Squibb Co Substituted acid derivatives useful as antiodiabetic and antiobesity agents and method
US6414002B1 (en) 1999-09-22 2002-07-02 Bristol-Myers Squibb Company Substituted acid derivatives useful as antidiabetic and antiobesity agents and method
HUP0203431A3 (en) * 1999-12-03 2003-11-28 Kyoto Pharma Ind Novel heterocyclic compounds and salts thereof and pharmaceutical compositions containing and use of the same
KR20040030647A (ko) 2001-05-29 2004-04-09 교토 야쿠힝 고교 가부시키가이샤 신규 복소환 화합물 및 그 의약 용도
JP4279137B2 (ja) 2001-05-29 2009-06-17 京都薬品工業株式会社 新規複素環誘導体およびその医薬用途
EP1481965B1 (en) * 2002-02-07 2015-07-29 Hitoshi Endo Aromatic amino acid derivatives and medicinal compositions
US6716842B2 (en) 2002-04-05 2004-04-06 Warner-Lambert Company, Llc Antidiabetic agents
EP1656368A4 (en) 2002-07-09 2009-08-26 Bristol Myers Squibb Co SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS ANTIDIABETIC AGENTS AND ANTIABESITY AND THEIR MANUFACTURING PROCESS
CN100467456C (zh) * 2004-05-24 2009-03-11 北京摩力克科技有限公司 作为hPPARα和/或hPPARγ激活剂的α-哌嗪取代的苯丙酸衍生物
CN100436430C (zh) * 2004-05-24 2008-11-26 北京摩力克科技有限公司 作为hPPARα和hPPARγ激动剂的烷酰基取代的酪氨酸衍生物
WO2008081537A1 (ja) * 2006-12-28 2008-07-10 Human Cell Systems, Inc. Ｌａｔ１阻害活性を有する芳香族アミノ酸誘導体、それを含有するｌａｔ１阻害活性剤及びその製造方法
JP6883589B2 (ja) 2016-05-02 2021-06-09 カーディアック ペースメイカーズ， インコーポレイテッド 電池のリチウムクラスタ成長の制御
WO2018049068A1 (en) * 2016-09-07 2018-03-15 Pliant Therapeutics, Inc. N-acyl amino acid compounds and methods of use

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01139528A (ja) 1987-11-24 1989-06-01 Showa Denko Kk 抗潰瘍剤
US5036079A (en) 1989-12-07 1991-07-30 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
US5089514A (en) * 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
IL99537A (en) 1990-09-27 1995-11-27 Merck & Co Inc Fibrinogen receptor antagonists and pharmaceutical compositions containing them
NZ239846A (en) 1990-09-27 1994-11-25 Merck & Co Inc Sulphonamide derivatives and pharmaceutical compositions thereof
EP0543018B1 (en) 1991-06-07 1996-01-10 Otsuka Pharmaceutical Co., Ltd. Antidiabetic agent
US5204350A (en) 1991-08-09 1993-04-20 Merck & Co., Inc. Method of inhibiting osteoclast-mediated bone resorption by administration of n-heterocyclicalkyl-substituted phenyl derivatives
US5206373A (en) 1992-02-28 1993-04-27 Merck & Co., Inc. Process for preparing fibrinogen receptor antagonists
US5312923A (en) 1992-02-28 1994-05-17 Merck & Co., Inc. Process for preparing fibrinogen receptor antagonists
US5246943A (en) 1992-05-19 1993-09-21 Warner-Lambert Company Substituted 1,2,3,4-tetahydroisoquinolines with angiotensin II receptor antagonist properties
KR0185225B1 (ko) 1992-05-21 1999-05-15 오오쓰까 아끼히꼬 포스폰산 디에스테르 유도체
US5236934A (en) 1992-08-26 1993-08-17 E. I. Du Pont De Nemours And Company 1,2,3,4-tetrahydroisoquinolines useful in the treatment of CNS disorders
WO1994012181A1 (en) 1992-12-01 1994-06-09 Merck & Co., Inc. Fibrinogen receptor antagonists
GB9225386D0 (en) 1992-12-04 1993-01-27 Smithkline Beecham Plc Novel compounds
GB9311644D0 (en) 1993-06-05 1993-07-21 Smithkline Beecham Plc Novel compounds
GB9311661D0 (en) 1993-06-05 1993-07-21 Smithkline Beecham Plc Novel compounds
US5491159A (en) * 1994-08-30 1996-02-13 American Home Products Corporation 2-(3,5-di-tert-butyl-4-hydroxy-phenyl)-oxazoles as anti-atherosclerotic agents
JP3485375B2 (ja) 1995-02-17 2004-01-13 株式会社資生堂 皮膚外用剤
JPH08325263A (ja) * 1995-05-31 1996-12-10 Sumitomo Metal Ind Ltd 新規２−アミノ−３−フェニルプロピオン酸誘導体
GB9604242D0 (en) * 1996-02-28 1996-05-01 Glaxo Wellcome Inc Chemical compounds
SK21099A3 (en) * 1996-08-19 2000-05-16 Japan Tobacco Inc Propionic acid derivatives and applications thereof
US6059964A (en) * 1998-12-03 2000-05-09 Alpine Stormwater Management Company Collapsible catch basin grate filter assembly

Also Published As

Publication number Publication date
IL121202A (en) 2001-08-26
EP0925063A1 (en) 1999-06-30
US6194446B1 (en) 2001-02-27
CA2259487A1 (en) 1998-01-08
IL121202A0 (en) 1997-11-20
WO1998000137A1 (en) 1998-01-08
US6541497B1 (en) 2003-04-01
ZA975865B (en) 1999-01-04
JP2000515133A (ja) 2000-11-14
US6353027B1 (en) 2002-03-05
EP0925063A4 (en) 2000-12-27

Similar Documents

Publication Publication Date Title
AU3719997A (en) Hypoglycemic and hypolipidemic compounds
AU7533696A (en) New materials
AU3550197A (en) Syringes
AU9790198A (en) Compounds and methods
AU3731995A (en) Hypoglycemic agent from cryptolepis
AU2832295A (en) Cytoanalyzer
AU4261697A (en) Compounds and methods
AU3619095A (en) Pyrazolylmethyl-thiazolidines useful as hypoglycemic agents
AU2445995A (en) Compacting granulator
AU2837895A (en) Thiazine- or thiazepine-derivatives
AU2523897A (en) A circulator and components thereof
AU1753495A (en) Pushing unit
AU4309696A (en) Compacts
AU8695298A (en) Compounds and uses thereof
AU1963395A (en) Boom-structure
AU3372495A (en) Derivatized polyester compounds and uses thereof
AU8693198A (en) Compounds and uses thereof
AU2895097A (en) New thiazolopyridines
AU1603595A (en) Meso-azanoradamantanes
AU2411395A (en) Hydrocopter
AUPO071196A0 (en) Compress
AU3776495A (en) Aryloxycycloalkenyl and aryloxyiminocycloalkenylhydroxyureas
AUPO662097A0 (en) Compress
AU5460398A (en) Antikinin compounds and uses thereof
AU693819B2 (en) Syringe