ZA975865B - Hypoglycemic and hypolipidemic compounds - Google Patents

Hypoglycemic and hypolipidemic compounds

Info

Publication number
ZA975865B
ZA975865B ZA975865A ZA975865A ZA975865B ZA 975865 B ZA975865 B ZA 975865B ZA 975865 A ZA975865 A ZA 975865A ZA 975865 A ZA975865 A ZA 975865A ZA 975865 B ZA975865 B ZA 975865B
Authority
ZA
South Africa
Prior art keywords
hypoglycemic
hypolipidemic compounds
hypolipidemic
compounds
Prior art date
Application number
ZA975865A
Other languages
English (en)
Inventor
Samuel James Dominianni
Margaret Mary Faul
Russell Dean Stucky
Leonard Larry Winneroski Jr
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA975865B publication Critical patent/ZA975865B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA975865A 1996-07-01 1997-07-01 Hypoglycemic and hypolipidemic compounds ZA975865B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2101696P 1996-07-01 1996-07-01

Publications (1)

Publication Number Publication Date
ZA975865B true ZA975865B (en) 1999-01-04

Family

ID=21801854

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA975865A ZA975865B (en) 1996-07-01 1997-07-01 Hypoglycemic and hypolipidemic compounds

Country Status (8)

Country Link
US (3) US6194446B1 (xx)
EP (1) EP0925063A4 (xx)
JP (1) JP2000515133A (xx)
AU (1) AU3719997A (xx)
CA (1) CA2259487A1 (xx)
IL (1) IL121202A (xx)
WO (1) WO1998000137A1 (xx)
ZA (1) ZA975865B (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9604242D0 (en) * 1996-02-28 1996-05-01 Glaxo Wellcome Inc Chemical compounds
CZ53699A3 (cs) 1996-08-19 1999-07-14 Japan Tobacco Inc. Deriváty propionové kyseliny a jejich použití
CA2306343C (en) * 1997-10-15 2010-08-03 American Home Products Corporation Novel aryloxy-alkyl-dialkylamines
US6005102A (en) * 1997-10-15 1999-12-21 American Home Products Corporation Aryloxy-alkyl-dialkylamines
CN1308620A (zh) * 1998-05-12 2001-08-15 美国家用产品公司 用于治疗胰岛素抗性和高血糖的联苯基磺酰基芳基羧酸
US6221902B1 (en) 1998-05-12 2001-04-24 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
AR016257A1 (es) * 1998-05-14 2001-06-20 Merck & Co Inc Proceso para la sintesis estereoselectiva de ariloxi-4-aza-5alfa-androstan-3-onas, 16 alfa y 16 beta-sustituidas e insustituidas, e intermediariosobtenidos en dicho proceso.
US6589969B1 (en) 1998-10-16 2003-07-08 Ono Pharmaceutical Co., Ltd. Carboxylic acid derivatives and drugs containing the same as the active ingredient
US6310081B1 (en) * 1999-05-10 2001-10-30 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
ES2258431T3 (es) 1999-08-02 2006-09-01 F. Hoffmann-La Roche Ag Proceso para la preparacion de derivados de benzotiofeno.
TWI260321B (en) 1999-09-22 2006-08-21 Bristol Myers Squibb Co Substituted acid derivatives useful as antidiabetic and antiobesity agents and method
US6414002B1 (en) 1999-09-22 2002-07-02 Bristol-Myers Squibb Company Substituted acid derivatives useful as antidiabetic and antiobesity agents and method
CN1215059C (zh) * 1999-12-03 2005-08-17 京都药品工业株式会社 新的杂环化合物及其盐和它们的医药用途
CZ20033450A3 (cs) 2001-05-29 2004-05-12 Kyotoápharmaceuticaláindustriesźáltd Heterocyklická sloučenina a její lékařské použití
PL367676A1 (en) 2001-05-29 2005-03-07 Kyoto Pharmaceutical Industries, Ltd. Novel heterocyclic derivatives and medicinal use thereof
CN1293042C (zh) * 2002-02-07 2007-01-03 远藤仁 芳香族氨基酸衍生物及其药物组合物
US6716842B2 (en) 2002-04-05 2004-04-06 Warner-Lambert Company, Llc Antidiabetic agents
PL374860A1 (en) 2002-07-09 2005-11-14 Bristol-Myers Squibb Company Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method
CN100467456C (zh) * 2004-05-24 2009-03-11 北京摩力克科技有限公司 作为hPPARα和/或hPPARγ激活剂的α-哌嗪取代的苯丙酸衍生物
CN100436430C (zh) * 2004-05-24 2008-11-26 北京摩力克科技有限公司 作为hPPARα和hPPARγ激动剂的烷酰基取代的酪氨酸衍生物
WO2008081537A1 (ja) * 2006-12-28 2008-07-10 Human Cell Systems, Inc. Ｌａｔ１阻害活性を有する芳香族アミノ酸誘導体、それを含有するｌａｔ１阻害活性剤及びその製造方法
EP4050694A1 (en) 2016-05-02 2022-08-31 Cardiac Pacemakers, Inc. Battery lithium cluster growth control
TW201823208A (zh) * 2016-09-07 2018-07-01 美商普萊恩醫療公司 N－醯基胺基酸化合物及其使用方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01139528A (ja) 1987-11-24 1989-06-01 Showa Denko Kk 抗潰瘍剤
US5036079A (en) 1989-12-07 1991-07-30 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
US5089514A (en) * 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
NZ239846A (en) 1990-09-27 1994-11-25 Merck & Co Inc Sulphonamide derivatives and pharmaceutical compositions thereof
IL99537A (en) 1990-09-27 1995-11-27 Merck & Co Inc Fibrinogen receptor antagonists and pharmaceutical preparations containing them
WO1992021342A1 (en) 1991-06-07 1992-12-10 Otsuka Pharmaceutical Co., Ltd. Antidiabetic
US5204350A (en) 1991-08-09 1993-04-20 Merck & Co., Inc. Method of inhibiting osteoclast-mediated bone resorption by administration of n-heterocyclicalkyl-substituted phenyl derivatives
US5312923A (en) * 1992-02-28 1994-05-17 Merck & Co., Inc. Process for preparing fibrinogen receptor antagonists
US5206373A (en) 1992-02-28 1993-04-27 Merck & Co., Inc. Process for preparing fibrinogen receptor antagonists
US5246943A (en) 1992-05-19 1993-09-21 Warner-Lambert Company Substituted 1,2,3,4-tetahydroisoquinolines with angiotensin II receptor antagonist properties
WO1993023409A1 (en) 1992-05-21 1993-11-25 Otsuka Pharmaceutical Factory, Inc. Phosphonic diester derivative
US5236934A (en) 1992-08-26 1993-08-17 E. I. Du Pont De Nemours And Company 1,2,3,4-tetrahydroisoquinolines useful in the treatment of CNS disorders
WO1994012181A1 (en) 1992-12-01 1994-06-09 Merck & Co., Inc. Fibrinogen receptor antagonists
GB9225386D0 (en) 1992-12-04 1993-01-27 Smithkline Beecham Plc Novel compounds
GB9311644D0 (en) 1993-06-05 1993-07-21 Smithkline Beecham Plc Novel compounds
GB9311661D0 (en) 1993-06-05 1993-07-21 Smithkline Beecham Plc Novel compounds
US5491159A (en) * 1994-08-30 1996-02-13 American Home Products Corporation 2-(3,5-di-tert-butyl-4-hydroxy-phenyl)-oxazoles as anti-atherosclerotic agents
JP3485375B2 (ja) 1995-02-17 2004-01-13 株式会社資生堂 皮膚外用剤
JPH08325263A (ja) * 1995-05-31 1996-12-10 Sumitomo Metal Ind Ltd 新規２−アミノ−３−フェニルプロピオン酸誘導体
GB9604242D0 (en) * 1996-02-28 1996-05-01 Glaxo Wellcome Inc Chemical compounds
CZ53699A3 (cs) * 1996-08-19 1999-07-14 Japan Tobacco Inc. Deriváty propionové kyseliny a jejich použití
US6059964A (en) * 1998-12-03 2000-05-09 Alpine Stormwater Management Company Collapsible catch basin grate filter assembly

Also Published As

Publication number Publication date
US6541497B1 (en) 2003-04-01
WO1998000137A1 (en) 1998-01-08
US6194446B1 (en) 2001-02-27
JP2000515133A (ja) 2000-11-14
CA2259487A1 (en) 1998-01-08
US6353027B1 (en) 2002-03-05
IL121202A0 (en) 1997-11-20
AU3719997A (en) 1998-01-21
EP0925063A4 (en) 2000-12-27
EP0925063A1 (en) 1999-06-30
IL121202A (en) 2001-08-26

Similar Documents

Publication Publication Date Title
IL121202A0 (en) Hypoglycemic and hypolipidemic compounds
PL318496A1 (en) Hypolipidemic compounds
GB9415926D0 (en) New materials
PL331901A1 (en) Syringe
PL331209A1 (en) Syringe
HUP0000432A3 (en) Insulin c-peptides
GB9411045D0 (en) Compounds and use
AU4309696A (en) Compacts
AU3372495A (en) Derivatized polyester compounds and uses thereof
GB9519235D0 (en) File
GB9607263D0 (en) File
GB9605272D0 (en) File
GB9901108D0 (en) Anti-reuse syringe
ZA988492B (en) Substituted tetrahydro-naphthalenes and analogous compounds
EP0799225A4 (en) COMPOUNDS AND RELATED METHODS
HUP0000089A3 (en) Syringe
GB9616563D0 (en) Compounds and methods
ZA978146B (en) Compound and process
GB9702178D0 (en) Constructional materials
EP0934345A4 (en) CONNECTIONS AND PROCEDURE
GB9612230D0 (en) Contsructional materials
GB9423171D0 (en) Hypolipidemic compounds
TW326757U (en) File (1)
GB9602513D0 (en) Compounds and process
CA73893S (en) Brief