AU2957502A - A process for the preparation of 1-(aminomethyl) cyclohexaneacetic acid - Google Patents

A process for the preparation of 1-(aminomethyl) cyclohexaneacetic acid

Info

Publication number
AU2957502A
AU2957502A AU2957502A AU2957502A AU2957502A AU 2957502 A AU2957502 A AU 2957502A AU 2957502 A AU2957502 A AU 2957502A AU 2957502 A AU2957502 A AU 2957502A AU 2957502 A AU2957502 A AU 2957502A
Authority
AU
Australia
Prior art keywords
gabapentin
hydrochloride
aminomethyl
preparation
cyclohexaneacetic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2957502A
Other languages
English (en)
Inventor
Massimo Ferrari
Marcello Ghezzi
Paolo Belotti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Erregierre SpA
Original Assignee
Erregierre SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erregierre SpA filed Critical Erregierre SpA
Publication of AU2957502A publication Critical patent/AU2957502A/xx
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/38—Separation; Purification; Stabilisation; Use of additives
    • C07C227/40—Separation; Purification
    • C07C227/42—Crystallisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2957502A 2000-12-01 2001-11-29 A process for the preparation of 1-(aminomethyl) cyclohexaneacetic acid Pending AU2957502A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000MI002608A IT1319674B1 (it) 2000-12-01 2000-12-01 Processo per la preparazione dell'acido1-(aminometil)cicloesanacetico.
PCT/EP2001/013953 WO2002044123A1 (en) 2000-12-01 2001-11-29 A process for the preparation of 1-(aminomethyl) cyclohexaneacetic acid

Publications (1)

Publication Number Publication Date
AU2957502A true AU2957502A (en) 2002-06-11

Family

ID=11446165

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2957502A Pending AU2957502A (en) 2000-12-01 2001-11-29 A process for the preparation of 1-(aminomethyl) cyclohexaneacetic acid
AU2002229575A Ceased AU2002229575B2 (en) 2000-12-01 2001-11-29 A process for the preparation of 1-(aminomethyl) cyclohexaneacetic acid

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2002229575A Ceased AU2002229575B2 (en) 2000-12-01 2001-11-29 A process for the preparation of 1-(aminomethyl) cyclohexaneacetic acid

Country Status (19)

Country Link
US (1) US7393974B2 (enExample)
EP (1) EP1347951B1 (enExample)
JP (1) JP2004521875A (enExample)
AT (1) ATE339400T1 (enExample)
AU (2) AU2957502A (enExample)
BR (1) BR0115755A (enExample)
CA (1) CA2436908A1 (enExample)
DE (1) DE60123125T2 (enExample)
ES (1) ES2271102T3 (enExample)
HR (1) HRP20030438A2 (enExample)
HU (1) HU228047B1 (enExample)
IL (2) IL156185A0 (enExample)
IT (1) IT1319674B1 (enExample)
MX (1) MXPA03004775A (enExample)
NZ (1) NZ526370A (enExample)
PL (1) PL361886A1 (enExample)
RU (1) RU2289572C2 (enExample)
WO (1) WO2002044123A1 (enExample)
ZA (1) ZA200304484B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7196216B2 (en) 2002-11-18 2007-03-27 Nicholas Piramal India Limited Process for preparation of Gabapentin
DE60235128D1 (de) 2002-11-20 2010-03-04 Hikal Ltd Verfahren zur herstellung von aminomethylcycloalkan-essigsäuren
US7439387B2 (en) 2003-04-21 2008-10-21 Matrix Laboratories Ltd. Process for the preparation of Gabapentin form-II
EP1636163A4 (en) * 2003-05-19 2006-08-09 Shasun Chemicals And Drugs Ltd PROCESS FOR THE PREPARATION OF GABAPENTIN
ITMI20042418A1 (it) * 2004-12-17 2005-03-17 Zambon Spa Processo per la purificazione della gabapentina
US7071356B1 (en) 2005-12-01 2006-07-04 Isp Investments Inc. Process for the preparation of 1-(aminomethyl) cyclohexaneacetic acid
EP2183211A1 (en) 2007-07-27 2010-05-12 Medichem, S.A. Method for preparing polymorph form ii of gabapentin
EP2368872A1 (en) 2010-03-25 2011-09-28 Serichim S.r.l. Process for the preparation of Gabapentin
ITMI20131757A1 (it) 2013-10-22 2015-04-23 Zach System Spa Processo di preparazione di gabapentina
EP3018131A1 (en) * 2014-11-07 2016-05-11 Bayer Pharma Aktiengesellschaft Synthesis of copanlisib and its dihydrochloride salt
EP3018127A1 (en) * 2014-11-07 2016-05-11 Bayer Pharma Aktiengesellschaft Synthesis of copanlisib and its dihydrochloride salt

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2460891C2 (de) 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US4960931A (en) 1988-05-02 1990-10-02 Warner-Lambert Company Gabapentin mohohydrate and a process for producing the same
DE3928184A1 (de) 1989-08-25 1991-02-28 Goedecke Ag Verfahren zur herstellung von cyclischen aminosaeurederivaten sowie zwischenprodukte
FI905584L (fi) * 1989-11-16 1991-05-17 Lonza Ag Foerfarande foer framstaellning av 1-(aminometyl)cyklohexanaettikssyra.
IL119890A (en) * 1996-12-24 2002-03-10 Teva Pharma Gabapentin form iii and preparation of gabapentin form ii
US6255526B1 (en) * 1996-12-24 2001-07-03 Teva Pharmaceutical Industries Ltd. Preparation of gabapentin

Also Published As

Publication number Publication date
WO2002044123A1 (en) 2002-06-06
MXPA03004775A (es) 2004-12-03
DE60123125D1 (de) 2006-10-26
JP2004521875A (ja) 2004-07-22
DE60123125T2 (de) 2007-03-01
ITMI20002608A1 (it) 2002-06-01
BR0115755A (pt) 2003-12-30
NZ526370A (en) 2003-08-29
PL361886A1 (en) 2004-10-04
RU2289572C2 (ru) 2006-12-20
IT1319674B1 (it) 2003-10-23
IL156185A0 (en) 2003-12-23
IL156185A (en) 2008-08-07
HUP0302642A3 (en) 2010-01-28
HU228047B1 (en) 2012-09-28
EP1347951B1 (en) 2006-09-13
HUP0302642A2 (hu) 2003-11-28
ES2271102T3 (es) 2007-04-16
HRP20030438A2 (en) 2004-08-31
AU2002229575B2 (en) 2006-12-07
ATE339400T1 (de) 2006-10-15
CA2436908A1 (en) 2002-06-06
US20050049432A1 (en) 2005-03-03
US7393974B2 (en) 2008-07-01
ZA200304484B (en) 2004-09-09
EP1347951A1 (en) 2003-10-01

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