ATE339400T1 - Verfahren zur herstellung von 1-(aminomethyl) cyclohexanessigsäure - Google Patents

Verfahren zur herstellung von 1-(aminomethyl) cyclohexanessigsäure

Info

Publication number
ATE339400T1
ATE339400T1 AT01990454T AT01990454T ATE339400T1 AT E339400 T1 ATE339400 T1 AT E339400T1 AT 01990454 T AT01990454 T AT 01990454T AT 01990454 T AT01990454 T AT 01990454T AT E339400 T1 ATE339400 T1 AT E339400T1
Authority
AT
Austria
Prior art keywords
gabapentin
hydrochloride
cyclohexanetic
aminomethyl
producing
Prior art date
Application number
AT01990454T
Other languages
German (de)
English (en)
Inventor
Massimo Ferrari
Marcello Ghezzi
Paolo Belotti
Original Assignee
Erregierre Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erregierre Spa filed Critical Erregierre Spa
Application granted granted Critical
Publication of ATE339400T1 publication Critical patent/ATE339400T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/38—Separation; Purification; Stabilisation; Use of additives
    • C07C227/40—Separation; Purification
    • C07C227/42—Crystallisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT01990454T 2000-12-01 2001-11-29 Verfahren zur herstellung von 1-(aminomethyl) cyclohexanessigsäure ATE339400T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2000MI002608A IT1319674B1 (it) 2000-12-01 2000-12-01 Processo per la preparazione dell'acido1-(aminometil)cicloesanacetico.

Publications (1)

Publication Number Publication Date
ATE339400T1 true ATE339400T1 (de) 2006-10-15

Family

ID=11446165

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01990454T ATE339400T1 (de) 2000-12-01 2001-11-29 Verfahren zur herstellung von 1-(aminomethyl) cyclohexanessigsäure

Country Status (19)

Country Link
US (1) US7393974B2 (enExample)
EP (1) EP1347951B1 (enExample)
JP (1) JP2004521875A (enExample)
AT (1) ATE339400T1 (enExample)
AU (2) AU2957502A (enExample)
BR (1) BR0115755A (enExample)
CA (1) CA2436908A1 (enExample)
DE (1) DE60123125T2 (enExample)
ES (1) ES2271102T3 (enExample)
HR (1) HRP20030438A2 (enExample)
HU (1) HU228047B1 (enExample)
IL (2) IL156185A0 (enExample)
IT (1) IT1319674B1 (enExample)
MX (1) MXPA03004775A (enExample)
NZ (1) NZ526370A (enExample)
PL (1) PL361886A1 (enExample)
RU (1) RU2289572C2 (enExample)
WO (1) WO2002044123A1 (enExample)
ZA (1) ZA200304484B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE418535T1 (de) 2002-11-18 2009-01-15 Nicholas Piramal India Ltd Verbessertes verfahren zur herstellung von gabapentin
ATE455089T1 (de) 2002-11-20 2010-01-15 Hikal Ltd Verfahren zur herstellung von aminomethylcycloalkan-essigsäuren
US7439387B2 (en) 2003-04-21 2008-10-21 Matrix Laboratories Ltd. Process for the preparation of Gabapentin form-II
WO2004101489A1 (en) * 2003-05-19 2004-11-25 Shasun Chemicals And Drugs Limited Process for the preparation of gabapentin
ITMI20042418A1 (it) * 2004-12-17 2005-03-17 Zambon Spa Processo per la purificazione della gabapentina
US7071356B1 (en) 2005-12-01 2006-07-04 Isp Investments Inc. Process for the preparation of 1-(aminomethyl) cyclohexaneacetic acid
EP2183211A1 (en) 2007-07-27 2010-05-12 Medichem, S.A. Method for preparing polymorph form ii of gabapentin
EP2368872A1 (en) 2010-03-25 2011-09-28 Serichim S.r.l. Process for the preparation of Gabapentin
ITMI20131757A1 (it) 2013-10-22 2015-04-23 Zach System Spa Processo di preparazione di gabapentina
EP3018131A1 (en) * 2014-11-07 2016-05-11 Bayer Pharma Aktiengesellschaft Synthesis of copanlisib and its dihydrochloride salt
EP3018127A1 (en) * 2014-11-07 2016-05-11 Bayer Pharma Aktiengesellschaft Synthesis of copanlisib and its dihydrochloride salt

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2460891C2 (de) 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US4960931A (en) 1988-05-02 1990-10-02 Warner-Lambert Company Gabapentin mohohydrate and a process for producing the same
DE3928184A1 (de) 1989-08-25 1991-02-28 Goedecke Ag Verfahren zur herstellung von cyclischen aminosaeurederivaten sowie zwischenprodukte
FI905584A7 (fi) * 1989-11-16 1991-05-17 Lonza Ag Menetelmä 1-(aminometyyli)sykloheksaanietikkahapon valmistamiseksi
US6255526B1 (en) * 1996-12-24 2001-07-03 Teva Pharmaceutical Industries Ltd. Preparation of gabapentin
IL119890A (en) * 1996-12-24 2002-03-10 Teva Pharma Gabapentin form iii and preparation of gabapentin form ii

Also Published As

Publication number Publication date
MXPA03004775A (es) 2004-12-03
AU2957502A (en) 2002-06-11
HU228047B1 (en) 2012-09-28
HUP0302642A3 (en) 2010-01-28
EP1347951A1 (en) 2003-10-01
DE60123125D1 (de) 2006-10-26
US7393974B2 (en) 2008-07-01
NZ526370A (en) 2003-08-29
IL156185A (en) 2008-08-07
HRP20030438A2 (en) 2004-08-31
DE60123125T2 (de) 2007-03-01
EP1347951B1 (en) 2006-09-13
PL361886A1 (en) 2004-10-04
IT1319674B1 (it) 2003-10-23
BR0115755A (pt) 2003-12-30
HUP0302642A2 (hu) 2003-11-28
WO2002044123A1 (en) 2002-06-06
US20050049432A1 (en) 2005-03-03
ITMI20002608A1 (it) 2002-06-01
CA2436908A1 (en) 2002-06-06
ZA200304484B (en) 2004-09-09
JP2004521875A (ja) 2004-07-22
IL156185A0 (en) 2003-12-23
ES2271102T3 (es) 2007-04-16
AU2002229575B2 (en) 2006-12-07
RU2289572C2 (ru) 2006-12-20

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Legal Events

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