IL156185A0 - A process for the preparation of 1-(aminomethyl) cyclohexaneacetic acid - Google Patents
A process for the preparation of 1-(aminomethyl) cyclohexaneacetic acidInfo
- Publication number
- IL156185A0 IL156185A0 IL15618501A IL15618501A IL156185A0 IL 156185 A0 IL156185 A0 IL 156185A0 IL 15618501 A IL15618501 A IL 15618501A IL 15618501 A IL15618501 A IL 15618501A IL 156185 A0 IL156185 A0 IL 156185A0
- Authority
- IL
- Israel
- Prior art keywords
- gabapentin
- hydrochloride
- aminomethyl
- preparation
- cyclohexaneacetic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/38—Separation; Purification; Stabilisation; Use of additives
- C07C227/40—Separation; Purification
- C07C227/42—Crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2000MI002608A IT1319674B1 (it) | 2000-12-01 | 2000-12-01 | Processo per la preparazione dell'acido1-(aminometil)cicloesanacetico. |
PCT/EP2001/013953 WO2002044123A1 (en) | 2000-12-01 | 2001-11-29 | A process for the preparation of 1-(aminomethyl) cyclohexaneacetic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
IL156185A0 true IL156185A0 (en) | 2003-12-23 |
Family
ID=11446165
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15618501A IL156185A0 (en) | 2000-12-01 | 2001-11-29 | A process for the preparation of 1-(aminomethyl) cyclohexaneacetic acid |
IL156185A IL156185A (en) | 2000-12-01 | 2003-05-28 | Process for the preparation of 1-(aminomethyl) cyclohexaneacetic acid |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL156185A IL156185A (en) | 2000-12-01 | 2003-05-28 | Process for the preparation of 1-(aminomethyl) cyclohexaneacetic acid |
Country Status (19)
Country | Link |
---|---|
US (1) | US7393974B2 (xx) |
EP (1) | EP1347951B1 (xx) |
JP (1) | JP2004521875A (xx) |
AT (1) | ATE339400T1 (xx) |
AU (2) | AU2957502A (xx) |
BR (1) | BR0115755A (xx) |
CA (1) | CA2436908A1 (xx) |
DE (1) | DE60123125T2 (xx) |
ES (1) | ES2271102T3 (xx) |
HR (1) | HRP20030438A2 (xx) |
HU (1) | HU228047B1 (xx) |
IL (2) | IL156185A0 (xx) |
IT (1) | IT1319674B1 (xx) |
MX (1) | MXPA03004775A (xx) |
NZ (1) | NZ526370A (xx) |
PL (1) | PL361886A1 (xx) |
RU (1) | RU2289572C2 (xx) |
WO (1) | WO2002044123A1 (xx) |
ZA (1) | ZA200304484B (xx) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7196216B2 (en) | 2002-11-18 | 2007-03-27 | Nicholas Piramal India Limited | Process for preparation of Gabapentin |
ES2339756T3 (es) | 2002-11-20 | 2010-05-25 | Hikal Ltd. | Procedimiento mejorado para la preparacion de acidos aminometilcicloalcanaceticos. |
US7439387B2 (en) | 2003-04-21 | 2008-10-21 | Matrix Laboratories Ltd. | Process for the preparation of Gabapentin form-II |
AU2003259544A1 (en) * | 2003-05-19 | 2004-12-03 | Shasun Chemicals And Drugs Limited | Process for the preparation of gabapentin |
ITMI20042418A1 (it) * | 2004-12-17 | 2005-03-17 | Zambon Spa | Processo per la purificazione della gabapentina |
US7071356B1 (en) | 2005-12-01 | 2006-07-04 | Isp Investments Inc. | Process for the preparation of 1-(aminomethyl) cyclohexaneacetic acid |
EP2183211A1 (en) | 2007-07-27 | 2010-05-12 | Medichem, S.A. | Method for preparing polymorph form ii of gabapentin |
EP2368872A1 (en) | 2010-03-25 | 2011-09-28 | Serichim S.r.l. | Process for the preparation of Gabapentin |
ITMI20131757A1 (it) | 2013-10-22 | 2015-04-23 | Zach System Spa | Processo di preparazione di gabapentina |
EP3018131A1 (en) * | 2014-11-07 | 2016-05-11 | Bayer Pharma Aktiengesellschaft | Synthesis of copanlisib and its dihydrochloride salt |
EP3018127A1 (en) * | 2014-11-07 | 2016-05-11 | Bayer Pharma Aktiengesellschaft | Synthesis of copanlisib and its dihydrochloride salt |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2460891C2 (de) | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
US4960931A (en) | 1988-05-02 | 1990-10-02 | Warner-Lambert Company | Gabapentin mohohydrate and a process for producing the same |
DE3928184A1 (de) | 1989-08-25 | 1991-02-28 | Goedecke Ag | Verfahren zur herstellung von cyclischen aminosaeurederivaten sowie zwischenprodukte |
US6255526B1 (en) * | 1996-12-24 | 2001-07-03 | Teva Pharmaceutical Industries Ltd. | Preparation of gabapentin |
IL119890A (en) * | 1996-12-24 | 2002-03-10 | Teva Pharma | Gabapentin form iii and preparation of gabapentin form ii |
-
2000
- 2000-12-01 IT IT2000MI002608A patent/IT1319674B1/it active
-
2001
- 2001-11-28 HU HU0302642A patent/HU228047B1/hu unknown
- 2001-11-29 CA CA002436908A patent/CA2436908A1/en not_active Abandoned
- 2001-11-29 DE DE60123125T patent/DE60123125T2/de not_active Expired - Fee Related
- 2001-11-29 RU RU2003119451/04A patent/RU2289572C2/ru not_active IP Right Cessation
- 2001-11-29 BR BR0115755-8A patent/BR0115755A/pt not_active IP Right Cessation
- 2001-11-29 PL PL36188601A patent/PL361886A1/xx not_active Application Discontinuation
- 2001-11-29 IL IL15618501A patent/IL156185A0/xx active IP Right Grant
- 2001-11-29 EP EP01990454A patent/EP1347951B1/en not_active Expired - Lifetime
- 2001-11-29 US US10/433,241 patent/US7393974B2/en not_active Expired - Fee Related
- 2001-11-29 WO PCT/EP2001/013953 patent/WO2002044123A1/en active IP Right Grant
- 2001-11-29 AT AT01990454T patent/ATE339400T1/de not_active IP Right Cessation
- 2001-11-29 NZ NZ526370A patent/NZ526370A/en unknown
- 2001-11-29 JP JP2002546493A patent/JP2004521875A/ja active Pending
- 2001-11-29 MX MXPA03004775A patent/MXPA03004775A/es active IP Right Grant
- 2001-11-29 AU AU2957502A patent/AU2957502A/xx active Pending
- 2001-11-29 AU AU2002229575A patent/AU2002229575B2/en not_active Ceased
- 2001-11-29 ES ES01990454T patent/ES2271102T3/es not_active Expired - Lifetime
-
2003
- 2003-05-28 IL IL156185A patent/IL156185A/en not_active IP Right Cessation
- 2003-05-30 HR HR20030438A patent/HRP20030438A2/hr not_active Application Discontinuation
- 2003-06-09 ZA ZA200304484A patent/ZA200304484B/en unknown
Also Published As
Publication number | Publication date |
---|---|
HU228047B1 (en) | 2012-09-28 |
NZ526370A (en) | 2003-08-29 |
IL156185A (en) | 2008-08-07 |
US7393974B2 (en) | 2008-07-01 |
US20050049432A1 (en) | 2005-03-03 |
AU2957502A (en) | 2002-06-11 |
HUP0302642A3 (en) | 2010-01-28 |
DE60123125T2 (de) | 2007-03-01 |
IT1319674B1 (it) | 2003-10-23 |
ITMI20002608A1 (it) | 2002-06-01 |
RU2289572C2 (ru) | 2006-12-20 |
HRP20030438A2 (en) | 2004-08-31 |
WO2002044123A1 (en) | 2002-06-06 |
EP1347951B1 (en) | 2006-09-13 |
AU2002229575B2 (en) | 2006-12-07 |
BR0115755A (pt) | 2003-12-30 |
HUP0302642A2 (hu) | 2003-11-28 |
CA2436908A1 (en) | 2002-06-06 |
ATE339400T1 (de) | 2006-10-15 |
DE60123125D1 (de) | 2006-10-26 |
JP2004521875A (ja) | 2004-07-22 |
ZA200304484B (en) | 2004-09-09 |
EP1347951A1 (en) | 2003-10-01 |
PL361886A1 (en) | 2004-10-04 |
MXPA03004775A (es) | 2004-12-03 |
ES2271102T3 (es) | 2007-04-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted |