AU2020245614B2 - Serotonin 5-HT2B inhibitory compounds - Google Patents
Serotonin 5-HT2B inhibitory compounds Download PDFInfo
- Publication number
- AU2020245614B2 AU2020245614B2 AU2020245614A AU2020245614A AU2020245614B2 AU 2020245614 B2 AU2020245614 B2 AU 2020245614B2 AU 2020245614 A AU2020245614 A AU 2020245614A AU 2020245614 A AU2020245614 A AU 2020245614A AU 2020245614 B2 AU2020245614 B2 AU 2020245614B2
- Authority
- AU
- Australia
- Prior art keywords
- imidazol
- methanone
- piperidin
- phenyl
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962825051P | 2019-03-28 | 2019-03-28 | |
| US62/825,051 | 2019-03-28 | ||
| PCT/US2020/024969 WO2020198478A1 (en) | 2019-03-28 | 2020-03-26 | Serotonin 5-ht2b inhibitory compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2020245614A1 AU2020245614A1 (en) | 2021-10-14 |
| AU2020245614B2 true AU2020245614B2 (en) | 2023-01-19 |
Family
ID=70775466
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2020245614A Active AU2020245614B2 (en) | 2019-03-28 | 2020-03-26 | Serotonin 5-HT2B inhibitory compounds |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US12240827B2 (https=) |
| EP (1) | EP3947360B1 (https=) |
| JP (1) | JP7454589B2 (https=) |
| CN (1) | CN113631548B (https=) |
| AU (1) | AU2020245614B2 (https=) |
| BR (1) | BR112021019314A2 (https=) |
| CA (1) | CA3134952C (https=) |
| DK (1) | DK3947360T3 (https=) |
| ES (1) | ES2991167T3 (https=) |
| FI (1) | FI3947360T3 (https=) |
| PL (1) | PL3947360T3 (https=) |
| PT (1) | PT3947360T (https=) |
| WO (1) | WO2020198478A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240027076A (ko) * | 2021-07-26 | 2024-02-29 | 조에티스 서비시즈 엘엘씨 | 세로토닌 5-ht2b 억제 화합물 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010080357A1 (en) * | 2008-12-18 | 2010-07-15 | Boehringer Ingelheim International Gmbh | Serotonin 5-ht2b receptor inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0515995D0 (en) | 2005-08-03 | 2005-09-07 | Sandoz Ag | Organic compounds |
| WO2007097197A1 (ja) * | 2006-02-20 | 2007-08-30 | Astellas Pharma Inc. | アミド誘導体またはその塩 |
| TWI415845B (zh) | 2006-10-03 | 2013-11-21 | Arena Pharm Inc | 用於治療與５-ｈｔ2ａ血清素受體相關聯病症之作為５-ｈｔ2ａ血清素受體之調節劑的吡唑衍生物 |
| US8697739B2 (en) | 2010-07-29 | 2014-04-15 | Novartis Ag | Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof |
-
2020
- 2020-03-26 PL PL20726982.0T patent/PL3947360T3/pl unknown
- 2020-03-26 US US17/441,340 patent/US12240827B2/en active Active
- 2020-03-26 EP EP20726982.0A patent/EP3947360B1/en active Active
- 2020-03-26 JP JP2021557368A patent/JP7454589B2/ja active Active
- 2020-03-26 PT PT207269820T patent/PT3947360T/pt unknown
- 2020-03-26 ES ES20726982T patent/ES2991167T3/es active Active
- 2020-03-26 FI FIEP20726982.0T patent/FI3947360T3/fi active
- 2020-03-26 WO PCT/US2020/024969 patent/WO2020198478A1/en not_active Ceased
- 2020-03-26 AU AU2020245614A patent/AU2020245614B2/en active Active
- 2020-03-26 CN CN202080024800.0A patent/CN113631548B/zh active Active
- 2020-03-26 DK DK20726982.0T patent/DK3947360T3/da active
- 2020-03-26 BR BR112021019314A patent/BR112021019314A2/pt unknown
- 2020-03-26 CA CA3134952A patent/CA3134952C/en active Active
-
2025
- 2025-01-21 US US19/032,924 patent/US20250179046A1/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010080357A1 (en) * | 2008-12-18 | 2010-07-15 | Boehringer Ingelheim International Gmbh | Serotonin 5-ht2b receptor inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| US20220162183A1 (en) | 2022-05-26 |
| US12240827B2 (en) | 2025-03-04 |
| PL3947360T3 (pl) | 2024-11-04 |
| CA3134952A1 (en) | 2020-10-01 |
| EP3947360A1 (en) | 2022-02-09 |
| AU2020245614A1 (en) | 2021-10-14 |
| US20250179046A1 (en) | 2025-06-05 |
| JP2022527080A (ja) | 2022-05-30 |
| JP7454589B2 (ja) | 2024-03-22 |
| DK3947360T3 (da) | 2024-08-26 |
| WO2020198478A8 (en) | 2021-09-16 |
| ES2991167T3 (es) | 2024-12-02 |
| CA3134952C (en) | 2023-08-08 |
| BR112021019314A2 (pt) | 2021-12-14 |
| CN113631548A (zh) | 2021-11-09 |
| FI3947360T3 (fi) | 2024-10-07 |
| CN113631548B (zh) | 2023-06-06 |
| EP3947360B1 (en) | 2024-08-07 |
| WO2020198478A1 (en) | 2020-10-01 |
| PT3947360T (pt) | 2024-09-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) |