ES2991167T3 - Compuestos inhibidores de la serotonina 5-ht2b - Google Patents

Compuestos inhibidores de la serotonina 5-ht2b Download PDF

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Publication number
ES2991167T3
ES2991167T3 ES20726982T ES20726982T ES2991167T3 ES 2991167 T3 ES2991167 T3 ES 2991167T3 ES 20726982 T ES20726982 T ES 20726982T ES 20726982 T ES20726982 T ES 20726982T ES 2991167 T3 ES2991167 T3 ES 2991167T3
Authority
ES
Spain
Prior art keywords
imidazol
methanone
piperidin
methyl
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES20726982T
Other languages
English (en)
Spanish (es)
Inventor
Richard Ewin
Govindan Subramanian
Jinxia Deng (Nancy)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zoetis Services LLC
Original Assignee
Zoetis Services LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zoetis Services LLC filed Critical Zoetis Services LLC
Application granted granted Critical
Publication of ES2991167T3 publication Critical patent/ES2991167T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES20726982T 2019-03-28 2020-03-26 Compuestos inhibidores de la serotonina 5-ht2b Active ES2991167T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962825051P 2019-03-28 2019-03-28
PCT/US2020/024969 WO2020198478A1 (en) 2019-03-28 2020-03-26 Serotonin 5-ht2b inhibitory compounds

Publications (1)

Publication Number Publication Date
ES2991167T3 true ES2991167T3 (es) 2024-12-02

Family

ID=70775466

Family Applications (1)

Application Number Title Priority Date Filing Date
ES20726982T Active ES2991167T3 (es) 2019-03-28 2020-03-26 Compuestos inhibidores de la serotonina 5-ht2b

Country Status (13)

Country Link
US (2) US12240827B2 (https=)
EP (1) EP3947360B1 (https=)
JP (1) JP7454589B2 (https=)
CN (1) CN113631548B (https=)
AU (1) AU2020245614B2 (https=)
BR (1) BR112021019314A2 (https=)
CA (1) CA3134952C (https=)
DK (1) DK3947360T3 (https=)
ES (1) ES2991167T3 (https=)
FI (1) FI3947360T3 (https=)
PL (1) PL3947360T3 (https=)
PT (1) PT3947360T (https=)
WO (1) WO2020198478A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240027076A (ko) * 2021-07-26 2024-02-29 조에티스 서비시즈 엘엘씨 세로토닌 5-ht2b 억제 화합물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0515995D0 (en) 2005-08-03 2005-09-07 Sandoz Ag Organic compounds
WO2007097197A1 (ja) * 2006-02-20 2007-08-30 Astellas Pharma Inc. アミド誘導体またはその塩
TWI415845B (zh) 2006-10-03 2013-11-21 Arena Pharm Inc 用於治療與５-ｈｔ2ａ血清素受體相關聯病症之作為５-ｈｔ2ａ血清素受體之調節劑的吡唑衍生物
JP2012512877A (ja) * 2008-12-18 2012-06-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング セロトニン５−ｈｔ２ｂ受容体阻害剤
US8697739B2 (en) 2010-07-29 2014-04-15 Novartis Ag Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof

Also Published As

Publication number Publication date
US20220162183A1 (en) 2022-05-26
US12240827B2 (en) 2025-03-04
PL3947360T3 (pl) 2024-11-04
CA3134952A1 (en) 2020-10-01
EP3947360A1 (en) 2022-02-09
AU2020245614A1 (en) 2021-10-14
US20250179046A1 (en) 2025-06-05
JP2022527080A (ja) 2022-05-30
JP7454589B2 (ja) 2024-03-22
DK3947360T3 (da) 2024-08-26
WO2020198478A8 (en) 2021-09-16
CA3134952C (en) 2023-08-08
BR112021019314A2 (pt) 2021-12-14
CN113631548A (zh) 2021-11-09
FI3947360T3 (fi) 2024-10-07
CN113631548B (zh) 2023-06-06
EP3947360B1 (en) 2024-08-07
WO2020198478A1 (en) 2020-10-01
AU2020245614B2 (en) 2023-01-19
PT3947360T (pt) 2024-09-20

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