AU2018202623A1 - Oxalate salts of Teneligliptin and solvates thereof, intermediates, process of prepration and markers thereof - Google Patents
Oxalate salts of Teneligliptin and solvates thereof, intermediates, process of prepration and markers thereof Download PDFInfo
- Publication number
- AU2018202623A1 AU2018202623A1 AU2018202623A AU2018202623A AU2018202623A1 AU 2018202623 A1 AU2018202623 A1 AU 2018202623A1 AU 2018202623 A AU2018202623 A AU 2018202623A AU 2018202623 A AU2018202623 A AU 2018202623A AU 2018202623 A1 AU2018202623 A1 AU 2018202623A1
- Authority
- AU
- Australia
- Prior art keywords
- oxalate
- teneligliptin
- salt
- hydrate
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN201721004095 | 2017-02-03 | ||
IN201721004095 | 2017-02-03 | ||
PCT/IB2018/050652 WO2018142327A1 (en) | 2017-02-03 | 2018-02-02 | Oxalate salts of teneligliptin and solvates thereof, intermediates, process of preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2018202623A1 true AU2018202623A1 (en) | 2018-08-23 |
Family
ID=63039388
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2018202623A Abandoned AU2018202623A1 (en) | 2017-02-03 | 2018-02-02 | Oxalate salts of Teneligliptin and solvates thereof, intermediates, process of prepration and markers thereof |
AU2018202960A Abandoned AU2018202960A1 (en) | 2017-02-03 | 2018-02-02 | Formulations comprising oxalate salts of Teneligliptin and solvates thereof |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2018202960A Abandoned AU2018202960A1 (en) | 2017-02-03 | 2018-02-02 | Formulations comprising oxalate salts of Teneligliptin and solvates thereof |
Country Status (10)
Country | Link |
---|---|
JP (2) | JP2019512460A (pt) |
KR (2) | KR20180100554A (pt) |
CN (2) | CN108697707A (pt) |
AU (2) | AU2018202623A1 (pt) |
BR (2) | BR112018010759A2 (pt) |
EA (1) | EA039402B1 (pt) |
MX (2) | MX2018006006A (pt) |
RU (2) | RU2742418C1 (pt) |
TW (2) | TW201831473A (pt) |
WO (2) | WO2018142334A1 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPWO2020209350A1 (pt) * | 2019-04-12 | 2020-10-15 | ||
CN110028496A (zh) * | 2019-04-26 | 2019-07-19 | 梯尔希(南京)药物研发有限公司 | 一种特力利汀相关杂质的合成方法 |
WO2021053564A1 (en) * | 2019-09-17 | 2021-03-25 | Glenmark Pharmaceuticals Limited | Pharmaceutical composition comprising remogliflozin or salt or ester thereof and teneligliptin or salt thereof |
KR20210121421A (ko) | 2020-03-30 | 2021-10-08 | 코오롱생명과학 주식회사 | 테네리글리프틴 2.5브롬화수소산염 무정형의 제조방법 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI319322B (en) * | 2003-11-13 | 2010-01-11 | Ono Pharmaceutical Co | Frozen-dried preperation containing prostaglandin |
CN102372704B (zh) * | 2005-02-18 | 2014-10-08 | 田边三菱制药株式会社 | 脯氨酸衍生物的盐,其溶剂合物,及其生产方法 |
KR20160143897A (ko) * | 2009-02-13 | 2016-12-14 | 베링거 인겔하임 인터내셔날 게엠베하 | Dpp-4 억제제(리나글립틴)을 임의로 다른 당뇨병 치료제와 병용하여 포함하는 당뇨병 치료 약제 |
MX364651B (es) * | 2009-11-27 | 2019-05-03 | Boehringer Ingelheim Int Gmbh Star | Inhibidores de dpp-iv, tales como la linagliptina, y composiciones farmacéuticas o combinaciones que comprenden los mismos, para usarse en el tratamiento de pacientes diabéticos tipificados genéticamente. |
TWI418370B (zh) * | 2009-12-18 | 2013-12-11 | Mitsubishi Tanabe Pharma Corp | 溶出安定性製劑 |
US9518048B2 (en) * | 2012-08-31 | 2016-12-13 | Glenmark Pharmaceuticals Limited | Process for the preparation of teneligliptin |
JP6088872B2 (ja) * | 2013-03-22 | 2017-03-01 | サラヤ株式会社 | ラクトン型ソホロリピッドの分解が抑制されたソホロリピッド粉末 |
WO2015012365A1 (ja) * | 2013-07-25 | 2015-01-29 | 株式会社 三和化学研究所 | 医薬製剤 |
WO2015019238A1 (en) * | 2013-08-06 | 2015-02-12 | Ranbaxy Laboratories Limited | Process for the preparation of n-protected (5s)-5-(1,3-thiazolidin-3-ylcarbonyl)pyrrolidin-3-one |
CN104650065A (zh) * | 2013-11-22 | 2015-05-27 | 天津市汉康医药生物技术有限公司 | 一种替格列汀化合物 |
WO2015132679A1 (en) * | 2014-03-05 | 2015-09-11 | Glenmark Pharmaceuticals Ltd | Teneligliptin compositions |
WO2015173779A1 (en) * | 2014-05-16 | 2015-11-19 | Micro Labs Limited | Process for the preparation of teneligliptin and its novel intermediates |
CN105294673B (zh) * | 2014-06-18 | 2018-04-13 | 四川科伦药物研究院有限公司 | 一种氢溴酸替格列汀的合成方法 |
WO2016051368A1 (en) * | 2014-10-01 | 2016-04-07 | Mylan Laboratories Ltd | Complex of amorphous empagliflozin and a cyclodextrin |
JP6027710B1 (ja) * | 2014-12-25 | 2016-11-16 | 田辺三菱製薬株式会社 | 糖尿病治療用固形製剤 |
-
2018
- 2018-02-02 MX MX2018006006A patent/MX2018006006A/es unknown
- 2018-02-02 JP JP2018537629A patent/JP2019512460A/ja active Pending
- 2018-02-02 WO PCT/IB2018/050662 patent/WO2018142334A1/en active Application Filing
- 2018-02-02 BR BR112018010759A patent/BR112018010759A2/pt not_active IP Right Cessation
- 2018-02-02 TW TW107103863A patent/TW201831473A/zh unknown
- 2018-02-02 BR BR112018010748A patent/BR112018010748A2/pt not_active IP Right Cessation
- 2018-02-02 KR KR1020187016406A patent/KR20180100554A/ko not_active Application Discontinuation
- 2018-02-02 KR KR1020187013773A patent/KR20180099635A/ko not_active IP Right Cessation
- 2018-02-02 CN CN201880000703.0A patent/CN108697707A/zh active Pending
- 2018-02-02 CN CN201880000427.8A patent/CN108884089A/zh active Pending
- 2018-02-02 MX MX2018006005A patent/MX2018006005A/es unknown
- 2018-02-02 RU RU2018120214A patent/RU2742418C1/ru active
- 2018-02-02 JP JP2018536796A patent/JP2019508385A/ja active Pending
- 2018-02-02 AU AU2018202623A patent/AU2018202623A1/en not_active Abandoned
- 2018-02-02 RU RU2018120216A patent/RU2018120216A/ru unknown
- 2018-02-02 EA EA201992376A patent/EA039402B1/ru unknown
- 2018-02-02 WO PCT/IB2018/050652 patent/WO2018142327A1/en active Application Filing
- 2018-02-02 AU AU2018202960A patent/AU2018202960A1/en not_active Abandoned
- 2018-02-05 TW TW107104026A patent/TW201834655A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
JP2019508385A (ja) | 2019-03-28 |
KR20180099635A (ko) | 2018-09-05 |
WO2018142327A1 (en) | 2018-08-09 |
JP2019512460A (ja) | 2019-05-16 |
CN108697707A (zh) | 2018-10-23 |
MX2018006006A (es) | 2019-05-16 |
BR112018010748A2 (pt) | 2018-12-04 |
KR20180100554A (ko) | 2018-09-11 |
TW201831473A (zh) | 2018-09-01 |
RU2742418C1 (ru) | 2021-02-05 |
BR112018010759A2 (pt) | 2018-12-04 |
WO2018142334A1 (en) | 2018-08-09 |
EA201992376A1 (ru) | 2020-03-23 |
RU2018120216A (ru) | 2021-05-07 |
MX2018006005A (es) | 2019-05-16 |
EA039402B1 (ru) | 2022-01-24 |
TW201834655A (zh) | 2018-10-01 |
CN108884089A (zh) | 2018-11-23 |
AU2018202960A1 (en) | 2018-08-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK5 | Application lapsed section 142(2)(e) - patent request and compl. specification not accepted |