AU2016279096B2 - Composition containing carboplatin and use - Google Patents
Composition containing carboplatin and use Download PDFInfo
- Publication number
- AU2016279096B2 AU2016279096B2 AU2016279096A AU2016279096A AU2016279096B2 AU 2016279096 B2 AU2016279096 B2 AU 2016279096B2 AU 2016279096 A AU2016279096 A AU 2016279096A AU 2016279096 A AU2016279096 A AU 2016279096A AU 2016279096 B2 AU2016279096 B2 AU 2016279096B2
- Authority
- AU
- Australia
- Prior art keywords
- dcp
- leukemia
- subject
- pharmaceutical composition
- body weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/282—Platinum compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562182124P | 2015-06-19 | 2015-06-19 | |
| US62/182,124 | 2015-06-19 | ||
| PCT/US2016/038333 WO2016205782A1 (en) | 2015-06-19 | 2016-06-20 | Composition containing carboplatin and use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2016279096A1 AU2016279096A1 (en) | 2018-01-04 |
| AU2016279096B2 true AU2016279096B2 (en) | 2021-01-07 |
Family
ID=57546650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2016279096A Ceased AU2016279096B2 (en) | 2015-06-19 | 2016-06-20 | Composition containing carboplatin and use |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10980768B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3297440A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2018517759A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20180014834A (cg-RX-API-DMAC7.html) |
| CN (1) | CN108697093A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2016279096B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112017027277A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2988989A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016205782A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112017024727A2 (pt) | 2015-05-18 | 2018-07-31 | Syn Nat Products Entpr Llc | cocristal, composição farmacêutica, método de tratamento de uma doença em um indivíduo e processo de produção de um cocristal |
| BR112017027277A2 (pt) | 2015-06-19 | 2018-09-04 | Syn Nat Products Entpr Llc | ?método para o tratamento ou prevenção de uma doença e métodos para matar uma célula? |
| AU2016279099B2 (en) | 2015-06-19 | 2021-09-23 | Syn-Nat Products Enterprise LLC | Pharmaceutical composition of carboplatin based co-crystals and use thereof |
| CN107847521A (zh) | 2015-06-25 | 2018-03-27 | 新纳特产品公司 | 药物共晶组合物及其用途 |
| AU2018372753B2 (en) * | 2017-11-21 | 2024-03-21 | Medoncare Pharmaceutical Co., Ltd | Combination product comprising dicycloplatin and preparation method and use thereof |
| CN108884119A (zh) * | 2018-02-22 | 2018-11-23 | 昆明贵研药业有限公司 | 一种双二羧酸二氨络铂(ii)衍生物的制备方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1186610A1 (en) * | 2000-03-03 | 2002-03-13 | Yang, Xuqing | Dicarboxylato diammine platinum derivatives and compositions comprising them as anti-tumor agents |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5922689A (en) | 1995-09-11 | 1999-07-13 | Unitech Pharmaceuticals, Inc. | Cisplatin analogs for cancer treatment |
| US6297245B1 (en) | 1998-08-04 | 2001-10-02 | Unitech Pharmaceuticals | Cisplatin and folic acid administered to treat breast cancer |
| KR100317473B1 (ko) | 1999-05-11 | 2001-12-22 | 이계호 | 신규의 백금(iv)착제 및 그 제조방법 |
| CN1314357A (zh) * | 2000-03-16 | 2001-09-26 | 杨旭清 | 双环酸铂抗癌药 |
| AUPQ641100A0 (en) | 2000-03-23 | 2000-04-15 | Australia Nuclear Science & Technology Organisation | Methods of synthesis and use of radiolabelled platinum chemotherapeutic ag ents |
| JP2004532260A (ja) | 2001-05-31 | 2004-10-21 | ザ チャイニーズ ユニバーシティ オブ ホンコン | デメチルカンタリジンをプラチナ含有抗がん剤と組み合わせて含む組成物およびその用途 |
| US7259270B2 (en) | 2001-11-30 | 2007-08-21 | Jingzun Wang | Supermolecular carboplatin derivatives, their preparation and pharmaceutical composition containing them as active ingredient and applications of the compositions |
| US7927613B2 (en) | 2002-02-15 | 2011-04-19 | University Of South Florida | Pharmaceutical co-crystal compositions |
| GEP20074134B (en) | 2002-08-19 | 2007-06-25 | Pfizer Prod Inc | Combination therapy for hyperproliferative diseases |
| WO2005016946A2 (en) | 2003-08-13 | 2005-02-24 | University Of South Florida | Platinum complexes for the treatment of tumors |
| DE602004025726D1 (de) * | 2003-11-14 | 2010-04-08 | Genvec Inc | Pharmazeutische verbindung zur behandlung von lokal fortgeschrittenem primär inoperablen pankreaskarzinom (lapc). |
| MX2007008810A (es) | 2005-01-21 | 2007-11-21 | Astex Therapeutics Ltd | Compuestos farmaceuticos. |
| CN100391437C (zh) * | 2005-09-12 | 2008-06-04 | 重庆医科大学附属第二医院 | 抗急性髓性白血病的gm-csf靶向药物脂质体及制备方法 |
| BRPI0708004A2 (pt) | 2006-01-30 | 2011-05-17 | Platco Technologies Proprietary Ltd | preparação de complexos de platina (ii) |
| CN1857221A (zh) * | 2006-04-14 | 2006-11-08 | 济南帅华医药科技有限公司 | 一种同载铂类化合物及其增效剂的抗癌缓释剂 |
| ES2556677T3 (es) * | 2006-08-02 | 2016-01-19 | Sunesis Pharmaceuticals, Inc. | Utilización combinada de ácido (+)-1,4-dihidro-7-[(3S,4S)-3-metoxi-4-(metilamino)-1-pirrolidinil]-4-oxo-1-(2-tiazolil)-1,8-naftiridin-3-carboxílico y citarabina (Ara-C) para el tratamiento de la leucemia |
| NZ591394A (en) * | 2008-09-15 | 2013-03-28 | Kasina Laila Innova Pharmaceuticals Private Ltd | Anti-cancer drugs and uses relating thereto for metastatic malignant melanoma and other cancers |
| CZ302618B6 (cs) | 2009-09-10 | 2011-08-03 | Univerzita Palackého | Cyklobutan-1,1-dikarboxylátokomplexy platiny s deriváty N6-benzyladeninu, zpusoby jejich prípravy a použití techto komplexu jako léciv v protinádorové terapii |
| US20110287110A1 (en) * | 2010-04-23 | 2011-11-24 | Mark Wesley Dewhirst | Combination cancer treatment |
| JP6091431B2 (ja) * | 2011-01-31 | 2017-03-15 | ルコラス−エム.ディー.リミテッド | 医薬的使用 |
| CN102924528B (zh) * | 2012-10-29 | 2015-04-15 | 东南大学 | 抗肿瘤二价铂配合物以及该配合物和其配体的制备方法 |
| EP2924044B1 (en) * | 2012-11-17 | 2018-10-31 | Beijing Shuobai Pharmaceutical Co., LTD | Platinum compound of malonic acid derivative having leaving group containing amino or alkylamino |
| CN103494838B (zh) | 2013-09-30 | 2016-05-11 | 武汉大学 | 一种化疗药物组合物 |
| MX361488B (es) | 2013-10-17 | 2018-12-07 | Vertex Pharma | Cocristales de (s)-n-metil-8-(1-((2'-metil-[4,5'-bipirimidin]-6-il ) amino)propan-2-il)quinolina-4-carboxamida y sus derivados deuterados como inhibidores de proteínas cinasa dependientes de adn (adn-pk). |
| CN111638234B (zh) * | 2014-08-13 | 2024-09-03 | 北京默加农生物技术发展有限公司 | 一种以双环铂为有效成分的药物的检测方法 |
| CN104127402B (zh) * | 2014-08-15 | 2019-08-30 | 北京默加农生物技术发展有限公司 | 双环铂在制备抗病毒药物和抗菌药物中的应用 |
| CN104693245A (zh) * | 2015-03-13 | 2015-06-10 | 卓越同达医药科技开发(苏州)有限公司 | 超分子抗癌药物双环铂的制备方法 |
| KR102432526B1 (ko) | 2015-04-10 | 2022-08-12 | 신-낫 프로덕츠 엔터프라이즈 엘엘씨 | 디시클로플라틴의 제조방법 |
| KR102569221B1 (ko) | 2015-04-22 | 2023-08-21 | 신-낫 프로덕츠 엔터프라이즈 엘엘씨 | 공결정 조성물 및 그의 약제학적 용도 |
| BR112017024727A2 (pt) | 2015-05-18 | 2018-07-31 | Syn Nat Products Entpr Llc | cocristal, composição farmacêutica, método de tratamento de uma doença em um indivíduo e processo de produção de um cocristal |
| AU2016279099B2 (en) | 2015-06-19 | 2021-09-23 | Syn-Nat Products Enterprise LLC | Pharmaceutical composition of carboplatin based co-crystals and use thereof |
| BR112017027277A2 (pt) | 2015-06-19 | 2018-09-04 | Syn Nat Products Entpr Llc | ?método para o tratamento ou prevenção de uma doença e métodos para matar uma célula? |
| CN107847521A (zh) | 2015-06-25 | 2018-03-27 | 新纳特产品公司 | 药物共晶组合物及其用途 |
-
2016
- 2016-06-20 BR BR112017027277A patent/BR112017027277A2/pt not_active IP Right Cessation
- 2016-06-20 US US15/736,170 patent/US10980768B2/en active Active
- 2016-06-20 CA CA2988989A patent/CA2988989A1/en not_active Abandoned
- 2016-06-20 KR KR1020187001614A patent/KR20180014834A/ko not_active Ceased
- 2016-06-20 CN CN201680035788.7A patent/CN108697093A/zh active Pending
- 2016-06-20 WO PCT/US2016/038333 patent/WO2016205782A1/en not_active Ceased
- 2016-06-20 JP JP2017566021A patent/JP2018517759A/ja active Pending
- 2016-06-20 EP EP16812606.8A patent/EP3297440A4/en not_active Withdrawn
- 2016-06-20 AU AU2016279096A patent/AU2016279096B2/en not_active Ceased
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1186610A1 (en) * | 2000-03-03 | 2002-03-13 | Yang, Xuqing | Dicarboxylato diammine platinum derivatives and compositions comprising them as anti-tumor agents |
Non-Patent Citations (2)
| Title |
|---|
| LI SU ET AL, "Phase I clinical trial of the novel platin complex dicycloplatin: clinical and pharmacokinetic results", INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS (2013), Vol. 51, No. 2, pp. 96 - 105 * |
| YU JJ ET AL, "Dicycloplatin, a Novel Platinum Analog in Chemotherapy: Synthesis of Chinese Pre-clinical and Clinical Profile and Emerging Mechanistic Studies", ANTICANCER RESEARCH,, (2014-01-01), vol. 34, no. 1, pages 455 - 463 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3297440A1 (en) | 2018-03-28 |
| CN108697093A (zh) | 2018-10-23 |
| BR112017027277A2 (pt) | 2018-09-04 |
| US20180169055A1 (en) | 2018-06-21 |
| US10980768B2 (en) | 2021-04-20 |
| WO2016205782A1 (en) | 2016-12-22 |
| EP3297440A4 (en) | 2019-04-10 |
| JP2018517759A (ja) | 2018-07-05 |
| AU2016279096A1 (en) | 2018-01-04 |
| CA2988989A1 (en) | 2016-12-22 |
| KR20180014834A (ko) | 2018-02-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |